Yan‐Tuan Li - Publications, H-index & Citations

Yan‐Tuan Li

Ocean University of China

28H指数

247论文数

2.8K被引数

收录论文 81

发表时间

The first dual-drug nanococrystal formulation of antiheart failure drug milrinone exhibiting enhanced in vitro/vivo pharmaceutical features: theoretical and experimental insights into interactions of excipient and cocrystal 首次展示增强体外/体内药理学特性的抗心力衰竭药物米力农双药纳米共晶制剂：辅料与共晶相互作用的实验与理论见解

Journal of Molecular Structure

IF4.7

2026-06-01

PREAI

Yu, Yue-Ming; Wu, Zhi-Yong; Li, Xue-Jie; Bu, Fan-Zhi; Li, Yan-Tuan

Design and self-assembly of nanomicelles loading 5-fluorouracil-ferulic acid cocrystal with synergistic antitumor activity: toward efficient encapsulation and sustained-release effect

DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY

IF2.2

2025-11-01

PREAI

Yu, Yue-Ming; Li, Xue-Jie; Zhao, Zhi-Long; Bu, Fan-Zhi; Wu, Zhi-Yong; Li, Yan-Tuan

Cocrystallization-driven bidirectional optimization tactic towards realizing the perfect combination of clinical drugs milrinone with furosemide at the molecular level 共结晶驱动的双向优化策略，旨在实现临床药物米力农与呋塞米在分子层面的完美组合

Journal of Molecular Structure

IF4.7

2025-08-05

PREAI

Yue-Ming Yu; Lu Liu; Fan-Zhi Bu; Zhi-Long Zhao; Zhi-Yong Wu; Yan-Tuan Li

Phenforminium fenbufenate as the first dual-drug molecular salt of phenformin with NSAIDs towards tuning dissolution behavior and enhancing synergic anticancer activity in vitro 苯乙双胍fenbufenate作为第一个与NSAIDs结合的苯乙双胍双药分子盐，用于调节溶解行为并增强体外协同抗癌活性。

Journal of Molecular Structure

IF4.7

2025-07-07

PREAI

Yu Song; Ming-Qing Wang; Li-Na Yu; Yuan Gao; Jie Bi; Lu-Hui Wang; Fan-Zhi Bu; Zhi-Yong Wu; Yan-Tuan Li

Effects of conformation of excipients succinic acid and maleic acid in molecular salts on in vitro/in vivo properties of marine drug cytarabine 分子盐中辅料琥珀酸和马来酸的构象对海洋药物阿糖胞苷体内外特性的影响

JOURNAL OF MOLECULAR STRUCTURE

IF4.7

2025-07-01

PREAI

Yu, Yue-Ming; Li, Xue-Jie; Zhao, Zhi-Long; Chen, Qiu-Tong; Bu, Fan-Zhi; Wu, Zhi-Yong; Li, Yan-Tuan

Cocrystallization of amantadine hydrochloride with nutrient: Insights into directed self- assembly and optimized biopharmaceutical character by integrating theory and experiment 盐酸金刚烷胺与营养物的共结晶：通过整合理论与实验，深入探讨定向自组装及优化生物药剂学特性

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

IF4.6

2025-05-23

PREAI

Bu, Fan-Zhi; Zhao, Ming-Yu; Wang, Ling-Yang; Wu, Zhi-Yong; Li, Yan-Tuan

An overview of polymeric nanomicelles in clinical trials and on the market (vol 32, pg 243, 2021)

CHINESE CHEMICAL LETTERS

IF8.9

2025-02-01

PREAI

Zheng, Xue; Xie, Jizhen; Zhang, Xing; Sun, Weiting; Zhao, Heyang; Li, Yantuan; Wang, Cheng

Bifonazole caffeate: The first molecular salt of bifonazole with enhanced biopharmaceutical property based on experiments and quantum chemistry research

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

IF4.6

2024-09-01

PREAI

Bu, Fan-Zhi; Meng, Su-Su; Wang, Ling-Yang; Wu, Zhi-Yong; Li, Yan-Tuan

Integrating Theory with Experimental Studies on the Directed Assembly of Phenforminium 5-Fluorouracilate toward Enhanced In Vitro/Vivo Properties and Synergistic Antitumor Efficacy

CRYSTAL GROWTH & DESIGN

IF3.4

2024-07-04

PREAI

Yu, Min; Yan, Jian-Qin; Wang, Ling-Yang; Wu, Zhi-Yong; Wu, Meng-Yao; Sun, Yong; Li, Yan-Tuan

Metforminium 5-fluorouracilate: The first codrug molecular salt of 5-fluorouracil demonstrating perfected in vitro/vivo characteristics and synergic antitumor effects

JOURNAL OF MOLECULAR STRUCTURE

IF4.7

2024-07-01

PREAI

Wang, Ling -Yang; Yu, Min; Liu, Chao-Long; Wu, Zhi-Yong; Wu, Meng-Yao; Sun, Yong; Li, Yan-Tuan

An integrated experimental and theoretical research on ternary salt-cocrystal of anti-heart failure medicine milrinone with different substituted benzoic acids

JOURNAL OF MOLECULAR STRUCTURE

IF4.7

2024-05-01

PREAI

Bu, Fan-Zhi; Meng, Su -Su; Wang, Ling -Yang; Wu, Zhi-Yong; Li, Yan-Tuan

Directed Self-Assembly with Gallic Acid Provides First Phenolic Acid Cocrystals for the Antiviral Drug Acyclovir toward Increasing Pharmaceutical Features and Synergy: A Theoretical and Experimental Integration Research (vol 23, pg 5868, 2023)

CRYSTAL GROWTH & DESIGN

IF3.4

2023-11-22

PREAI

Bu, Fan-Zhi; Yu, Yue-Ming; Zhang, Min; Yan, Cui-Wei; Wu, Zhi-Yong; Li, Yan-Tuan

The first nano-cocrystal formulation of marine drug cytarabine with uracil based on cocrystal nanonization strategy for long-acting injection exhibiting enhanced antitumor activity

INTERNATIONAL JOURNAL OF PHARMACEUTICS

IF5.2

2023-09-01

PREAI

Yu, Yue-Ming; Bu, Fan-Zhi; Meng, Su-Su; Yan, Cui-Wei; Wu, Zhi-Yong; Li, Yan-Tuan

First cocrystal of esculetin: Simultaneously optimized in vitro/vivo properties and antioxidant effect

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

IF4.7

2023-08-01

OAAI

Liu, Fang; Li, Jin-Yang; Han, Cai-Bei; Wang, Jun-Hao; Tong, Si-Yi; Wang, Xue-Kun; Li, Yan-Tuan; Sun, Wen-Jun

CRYSTAL GROWTH & DESIGN

IF3.4

2023-07-18

PREAI

Bu, Fan-Zhi; Yu, Yue-Ming; Zhang, Min; Yan, Cui-Wei; Wu, Zhi-Yong; Li, Yan-Tuan

The molecular salt of pyrimethamine and fenbufen for enhancing dissolubility via an assisted efficacy-increasing approach of dual-drug salt formation: A combined study including theory analysis and experiment validation

JOURNAL OF MOLECULAR STRUCTURE

IF4.7

2023-07-01

PREAI

Shen, Yu-Li; Bu, Fan-Zhi; Yu, Yue-Ming; Meng, Su-Su; Wu, Zhi-Yong; Yan, Cui-Wei; Li, Yan-Tuan

Cocrystallization with nutrient ferulic acid towards reducing the dissolubility behaviors of antifungal drug 5-fluorocytosine: An integrated theoretical and experimental case research

JOURNAL OF MOLECULAR STRUCTURE

IF4.7

2023-03-01

PREAI

Bu, Fan-Zhi; Yu, Yue-Ming; Shen, Yu-Li; Wu, Zhi-Yong; Li, Yan-Tuan

Hepatoprotective Pyrazinamide-Baicalein Cocrystal with a Rare Ratio of 7:3

CRYSTAL GROWTH & DESIGN

IF3.4

2023-01-03

PREAI

Hao, Shu-Yun; Li, Jin-Yang; Mu, Chong-Qiang; Liu, Deng-Shuo; Yang, Yu; Li, Yan-Tuan; Liu, Tie-Min; Wang, Xue-Kun; Liu, Fang

Supramolecular self-assembly of amantadine hydrochloride with ferulic acid via dual optimization strategy establishes a precedent of synergistic antiviral drug-phenolic acid nutraceutical cocrystal(vol 146, pg 3988, 2021)

ANALYST

IF3.3

2023-01-01

OAAI

Wang, Ling-Yang; Niu, Yuan-Yuan; Zhao, Ming-Yu; Yu, Yue-Ming; Li, Yan-Tuan; Wu, Zhi-Yong; Yan, Cui-Wei

Comparative study of the cocrystals with layered/cavity structure in regulating in vitro pharmaceutical properties of diuretic acetazolamide

JOURNAL OF MOLECULAR STRUCTURE

IF4.7

2023-01-01

PREAI

Bai, Guang-Yao; Wu, Zhi-Yong; Xing, Jin-Lei; Li, Yan-Tuan

研究方向