未登录 Deficient synaptic neurotransmission results in a persistent sleep-like cortical activity across vigilance states in mice 突触神经传递功能缺陷会导致小鼠在不同警觉状态下出现持续性的类睡眠样皮层活动。 Guillaumin, Mathilde C. C.; Harding, Christian D.; Krone, Lukas B.; Yamagata, Tomoko; Kahn, Martin C.; Blanco-Duque, Cristina; Banks, Gareth T.; Achermann, Peter; Behn, Cecilia Diniz; Nolan, Patrick M.; Peirson, Stuart N.; Vyazovskiy, Vladyslav V. 分享 收藏
A missense mutation in zinc finger homeobox-3 (ZFHX3) impedes growth and alters metabolism and hypothalamic gene expression in mice Nolan, Patrick M.; Banks, Gareth; Bourbia, Nora; Wilcox, Ashleigh G.; Bentley, Liz; Moir, Lee; Kent, Lee; Hillier, Rosie; Wilson, Dana; Barrett, Perry; Dumbell, Rebecca 分享 收藏
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Comprehensive phenotypic analysis of the Dp1Tyb mouse strain reveals a broad range of Down syndrome-related phenotypes Lana-Elola, Eva; Cater, Heather; Watson-Scales, Sheona; Greenaway, Simon; Mueller-Winkler, Jennifer; Gibbins, Dorota; Nemes, Mihaela; Slender, Amy; Hough, Tertius; Keskivali-Bond, Piia; Scudamore, Cheryl L.; Herbert, Eleanor; Banks, Gareth T.; Mobbs, Helene; Canonica, Tara; Tosh, Justin; Noy, Suzanna; Llorian, Miriam; Nolan, Patrick M.; Griffin, Julian L.; Good, Mark; Simon, Michelle; Mallon, Ann-Marie; Wells, Sara; Fisher, Elizabeth M. C.; Tybulewicz, Victor L. J. 分享 收藏
Zfhx3 modulates retinal sensitivity and circadian responses to light Hughes, Steven; Edwards, Jessica K.; Wilcox, Ashleigh G.; Pothecary, Carina A.; Barnard, Alun R.; Joynson, Russell; Joynson, Greg; Hankins, Mark W.; Peirson, Stuart N.; Banks, Gareth; Nolan, Patrick M. 分享 收藏
Forward genetics identifies a novel sleep mutant with sleep state inertia and REM sleep deficits Banks, Gareth T.; Guillaumin, Mathilde C. C.; Heise, Ines; Lau, Petrina; Yin, Minghui; Bourbia, Nora; Aguilar, Carlos; Bowl, Michael R.; Esapa, Chris; Brown, Laurence A.; Hasan, Sibah; Tagliatti, Erica; Nicholson, Elizabeth; Bains, Rasneer Sonia; Wells, Sara; Vyazovskiy, Vladyslav V.; Volynski, Kirill; Peirson, Stuart N.; Nolan, Patrick M. 分享 收藏
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Loss of Frrs1l disrupts synaptic AMPA receptor function, and results in neurodevelopmental, motor, cognitive and electrographical abnormalities Frrs1l的缺失会破坏突触AMPA受体的功能，并导致神经发育，运动，认知和电描记异常 Stewart, Michelle; Lau, Petrina; Banks, Gareth; Bains, Rasneer Sonia; Castroflorio, Enrico; Oliver, Peter L.; Dixon, Christine L.; Kruer, Michael C.; Kullmann, Dimitri M.; Acevedo-Arozena, Abraham; Wells, Sara E.; Corrochano, Silvia; Nolan, Patrick M. 分享 收藏
Differential roles for cryptochromes in the mammalian retinal clock Wong, Jovi C. Y.; Smyllie, Nicola J.; Banks, Gareth T.; Pothecary, Carina A.; Barnard, Alun R.; Maywood, Elizabeth S.; Jagannath, Aarti; Hughes, Steven; van der Horst, Gijsbertus T. J.; MacLaren, Robert E.; Hankins, Mark W.; Hastings, Michael H.; Nolan, Patrick M.; Foster, Russell G.; Peirson, Stuart N. 分享 收藏
The after-hours circadian mutant has reduced phenotypic plasticity in behaviors at multiple timescales and in sleep homeostasis 小时后昼夜节律突变体在多个时间尺度和睡眠稳态下的行为中降低了表型可塑性 Maggi, Silvia; Balzani, Edoardo; Lassi, Glenda; Garcia-Garcia, Celina; Plano, Andrea; Espinoza, Stefano; Mus, Liudmila; Tinarelli, Federico; Nolan, Patrick M.; Gainetdinov, Raul R.; Balci, Fuat; Nieus, Thierry; Tucci, Valter 分享 收藏
Disruption of the homeodomain transcription factor orthopedia homeobox (Otp) is associated with obesity and anxiety Moir, Lee; Bochukova, Elena G.; Dumbell, Rebecca; Banks, Gareth; Bains, Rasneer S.; Nolan, Patrick M.; Scudamore, Cheryl; Simon, Michelle; Watson, Kimberly A.; Keogh, Julia; Henning, Elena; Hendricks, Audrey; O'Rahilly, Stephen; Barroso, Ines; Sullivan, Adrienne E.; Bersten, David C.; Whitelaw, Murray L.; Kirsch, Susan; Bentley, Elizabeth; Farooqi, I. Sadaf; Cox, Roger D. 分享 收藏
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A missense mutation in Katnal1 underlies behavioural, neurological and ciliary anomalies Banks, G.; Lassi, G.; Hoerder-Suabedissen, A.; Tinarelli, F.; Simon, M. M.; Wilcox, A.; Lau, P.; Lawson, T. N.; Johnson, S.; Rutman, A.; Sweeting, M.; Chesham, J. E.; Barnard, A. R.; Horner, N.; Westerberg, H.; Smith, L. B.; Molnar, Z.; Hastings, M. H.; Hirst, R. A.; Tucci, V.; Nolan, P. M. 分享 收藏
Novel gene function revealed by mouse mutagenesis screens for models of age-related disease Potter, Paul K.; Bowl, Michael R.; Jeyarajan, Prashanthini; Wisby, Laura; Blease, Andrew; Goldsworthy, Michelle E.; Simon, Michelle M.; Greenaway, Simon; Michel, Vincent; Barnard, Alun; Aguilar, Carlos; Agnew, Thomas; Banks, Gareth; Blake, Andrew; Chessum, Lauren; Dorning, Joanne; Falcone, Sara; Goosey, Laurence; Harris, Shelley; Haynes, Andy; Heise, Ines; Hillier, Rosie; Hough, Tertius; Hoslin, Angela; Hutchison, Marie; King, Ruairidh; Kumar, Saumya; Lad, Heena V.; Law, Gemma; MacLaren, Robert E.; Morse, Susan; Nicol, Thomas; Parker, Andrew; Pickford, Karen; Sethi, Siddharth; Starbuck, Becky; Stelma, Femke; Cheeseman, Michael; Cross, Sally H.; Foster, Russell G.; Jackson, Ian J.; Peirson, Stuart N.; Thakker, Rajesh V.; Vincent, Tonia; Scudamore, Cheryl; Wells, Sara; El-Amraoui, Aziz; Petit, Christine; Acevedo-Arozena, Abraham; Nolan, Patrick M.; Cox, Roger; Mallon, Anne-Marie; Brown, Steve D. M. 分享 收藏
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Analysis of Individual Mouse Activity in Group Housed Animals of Different Inbred Strains Using a Novel Automated Home Cage Analysis System Bains, Rasneer S. i; Cater, Heather L.; Sillito, Rowland R.; Chartsias, Agisilaos; Sneddon, Duncan; Concas, Danilo; Keskivali-Bond, Piia; Lukins, Timothy C.; Wells, Sara; Arozena, Abraham Acevedo; Nolan, Patrick M.; Armstrong, J. Douglas 分享 收藏
Loss-of-Function Mutations in FRRS1L Lead to an Epileptic-Dyskinetic Encephalopathy Madeo, Marianna; Stewart, Michelle; Sun, Yuyang; Sahir, Nadia; Wiethoff, Sarah; Chandrasekar, Indra; Yarrow, Anna; Rosenfeld, Jill A.; Yang, Yaping; Cordeiro, Dawn; McCormick, Elizabeth M.; Muraresku, Colleen C.; Jepperson, Tyler N.; McBeth, Lauren J.; Seidahmed, Mohammed Zain; El Khashab, Heba Y.; Hamad, Muddathir; Azzedine, Hamid; Clark, Karl; Corrochano, Silvia; Wells, Sara; Elting, Mariet W.; Weiss, Marjan M.; Burn, Sabrina; Myers, Angela; Landsverk, Megan; Crotwell, Patricia L.; Waisfisz, Quinten; Wolf, Nicole I.; Nolan, Patrick M.; Padilla-Lopez, Sergio; Houlden, Henry; Lifton, Richard; Mane, Shrikant; Singh, Brij B.; Falk, Marni J.; Mercimek-Mahmutoglu, Saadet; Bilguvar, Kaya; Salih, Mustafa A.; Acevedo-Arozena, Abraham; Kruer, Michael C. 分享 收藏
Early doors (Edo) mutant mouse reveals the importance of period 2 (PER2) PAS domain structure for circadian pacemaking Militi, Stefania; Maywood, Elizabeth S.; Sandate, Colby R.; Chesham, Johanna E.; Barnard, Alun R.; Parsons, Michael J.; Vibert, Jennifer L.; Joynson, Greg M.; Partch, Carrie L.; Hastings, Michael H.; Nolan, Patrick M. 分享 收藏
Eye diseases identified in the ENU-Ageing Screen Jackson, I.; Starbuck, B.; McKie, L.; Banks, G.; Blease, A.; Simon, M.; Wisby, L.; Cross, S.; Nolan, P.; Brown, S.; Potter, P. 分享 收藏
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