Jean‐Sébastien Frenel - Publications, H-index & Citations

Jean‐Sébastien Frenel

institut de cancerologie de l'ouest

38H指数

409论文数

8.1K被引数

收录论文 155

发表时间

Chemotherapy outcomes in human epidermal growth factor receptor 2-low, hormone receptor-positive metastatic breast cancer: Insights from the French multicenter ESME database 人表皮生长因子受体2低表达、激素受体阳性转移性乳腺癌的化疗结局：来自法国多中心ESME数据库的见解

Breast

IF7.9

2026-09-27

OAAI

William Jacot; Pauline Macouillard; Suyuan Zhang; Danalyn Byng; Shannon Hunter; Vincent Massard; Jean-Sébastien Frenel; David Pérol; Etienne Brain; Audrey Mailliez; Thomas Bachelot; Monica Arnedos; Lise Bosquet; Véronique Diéras

Combined prognostic value of age at onset and socioeconomic status for long-term survival in metastatic breast cancer 发病年龄和社会经济地位对转移性乳腺癌长期生存的联合预后价值

Scientific Reports

IF3.9

2026-09-05

OAAI

Ke Zhou; German Cano-Sancho; Caroline Goupille; Vincent Bessonneau; Eva Gorrochategui Matas; Christine Bobin-Dubigeon; Jean-Sébastien Frenel; Martine Bellanger

Efficacy and safety of immune checkpoint inhibitor rechallenge in cervical and endometrial cancer: a multi-center retrospective study (RICE study)

International Journal of Gynecological Cancer

IF4.7

2026-07-15

PREAI

Rayan Kabirian; Mathilde de Saint Ghislain; Olivia Le Saux; Laurent Mathiot; Jean-Sébastien Frenel; Paule Augereau; Alexandra Forestier; Jean David Fumet; Lauriane Eberst; Stanislas Quesada; Elsa Kalbacher; Céline Lescure; Thibault De La Motte Rouge; Juan Francisco Grau Bejar; Solenn Barraud; Thomas Genevee; Diana Bello Roufai; Manuel Rodrigues; Alexandra Leary

Risk stratification and relapse pattern in triple-negative breast cancer with pathological complete response after neoadjuvant treatment: the European GAMBIT real-world study

Nature Communications

IF15.7

2026-06-24

OAAI

Davide Massa; Theodoros Foukakis; Sylvie Giacchetti; Christine Desmedt; Jean-Sebastien Frenel; Elisa Gasparini; Marleen Kok; Paolo Vigneri; William Jacot; Claudio Vernieri; Matteo Lambertini; Francesca Patanè; Federico Piacentini; Emilio Bria; Alberto Zambelli; Dario Trapani; Andrea Botticelli; Ornella Garrone; Stefania Lando; Alexios Matikas; Laetitia Someil; Giuseppe Floris; Mario Campone; Moira Ragazzi; Esther Lips; Federica Martorana; Giorgio Bonomi; Andri Papakonstantinou; Lorenzo Nicolè; Ioannis Zerdes; Patrick Neven; Martina Rotolo; Hugo Horlings; Sabrina Nucera; Amélie Gudin-De-Vallerin; Andrea Vingiani; Angelo Paolo Dei Tos; Valentina Guarneri; Maria Vittoria Dieci

Tucatinib in patients with HER2-positive advanced/metastatic breast cancer: a systematic literature review of real-world evidence 曲拉曲坦在HER2阳性晚期/转移性乳腺癌患者中的应用：一项真实世界证据的系统文献综述

The Breast

IF0

2026-06-09

OAAI

Rodrigo Sanchez-Bayona; Carey Anders; Rupert Bartsch; David A. Cameron; Eva M. Ciruelos; Carmen Criscitiello; Francois P. Duhoux; Theodoros Foukakis; Jean-Sebastien Frenel; Joseph Gligorov; Peter A. Kaufman; Matteo Lambertini; Nathalie LeVasseur; Alicia Okines; Frédérique Penault-Llorca; Volkmar Müller; Matthew T. Blahna; Edward Neuberger; Sofia Simon; Emanuele Zanucco

Characteristics, treatment and survival of older patients with metastatic triple negative breast cancer from the ESME mBC real-world national cohort: a comparison with younger women 老年转移性三阴性乳腺癌患者的特征、治疗及生存情况：基于ESME mBC真实世界全国队列研究，并与年轻女性进行比较

The Breast

IF0

2026-05-22

OAAI

Mathilde Mairé; Fanny Bouteiller; Camille Chakiba; William Jacot; Romain Geiss; Mony Ung; Anthony Goncalves; Jean-Sébastien Frenel; Caroline Bailleux; Christophe Perrin; Vincent Massard; Audrey Mailliez; Christelle Jouannaud; François Cherifi; Thierry Petit; Catherine Terret; Alessandro Viansone; Lise Bosquet; Angéline Galvin

Characteristics and outcomes of patients with HER2-negative metastatic breast cancers with low expression of estrogen and progesterone receptors in the multicenter ESME cohort.HER2阴性低表达雌激素和孕激素受体转移性乳腺癌患者的特征和结局：多中心ESME队列研究

The Breast

IF0

2026-05-18

OAAI

Marie Alexandre; Eva Teruel; Florence Dalenc; Thibaut de la Motte Rouge; Etienne Brain; Vincent Massard; Monica Arnedos; Audrey Mailliez; Jean-Marc Ferrero; Thomas Bachelot; Isabelle Desmoulins; Marie-Ange Mouret-Reynier; Christelle Levy; Antony Gonçalves; Anca Berghian; Thierry Petit; Jean-Sébastien Frenel; Anne-Laure Martin; Thomas Grinda; William Jacot

Deep Learning-based Prediction of Homologous Recombination Deficiency from Histopathological Whole Slide Images in Ovarian Cancer 基于深度学习的卵巢癌组织病理学全切片图像同源重组缺陷预测

International Journal of Gynecological Cancer

IF4.7

2026-04-18

PREAI

J.-S. Frenel; P.-E. Heudel; E. Guinaudeau; C. Bossard; G. Lindahl; J. Rynkiewicz; S. Salhi; Y. Salhi; J. Chetritt; E. Pujade-Lauraine; I. Ray-Coquard

BRCA1/2, PALB2 mutations and first-line CDK4/6 inhibitor efficacy in HR+ metastatic breast cancer BRCA1/2、PALB2基因突变与HR+转移性乳腺癌中一线CDK4/6抑制剂疗效

The Breast

IF0

2026-02-16

OAAI

Timothé Guinel; Amélie Lusque; Audrey Mailliez; Vincent Massard; William Jacot; Severine Guiu; Thibault de la Motte Rouge; Etienne Brain; Isabelle Desmoulins; Monica Arnedos; Caroline Bailleux; Anthony Goncalves; Christelle Levy; Thomas Bachelot; Lise Bosquet; Suzette Delaloge; Jean-Sébastien Frénel

Favourable long-term outcomes in selected HER2-Positive early breast cancer patients without pathological complete response after neoadjuvant chemotherapy and trastuzumab: A pre-T-DM1 era cohort study 在未获得病理完全缓解的HER2阳性早期乳腺癌患者中，新辅助化疗联合曲妥珠单抗治疗后的长期预后良好：一项预T-DM1时代的队列研究

Cancer Treatment and Research Communications

IF2.4

2026-01-01

OAAI

Doucet, Ludovic; Moreau-Bachelard, Camille; Mathiot, Laurent; Kerdraon, Olivier; Robert, Marie; Quintin, Julie; Bocquet, Francois; Zenatri, Morgan; Campone, Mario; Frenel, Jean-Sebastien

Recent treatment and survival trends in older versus younger women with HR-positive HER2-negative metastatic breast cancer in the real-life multicenter French ESME cohort 老年与年轻HR阳性HER2阴性转移性乳腺癌女性患者真实世界多中心法国ESME队列中的近期治疗与生存趋势

European Journal of Cancer

IF7.1

2025-12-05

PREAI

Fanny Bouteiller; Sophie Gourgou; Michaël Bringuier; Angéline Galvin; Audrey Mailliez; Nicolas Bertrand; Mony Hung; Jean-Sébastien Frenel; Vincent Massard; Thomas Bachelot; Carole Plumio; Anthony Gonçalves; Christelle Levy; Lise Bosquet; William Jacot; Suzette Delaloge; Thomas Grinda; Carine Bellera

PROMENADE: pembrolizumab for early ER-low/HER2-negative breast cancer, real-world French cohort PROMENADE研究：早期ER低表达/HER2阴性乳腺癌患者接受pembrolizumab治疗的真实世界法国队列研究

ESMO Open

IF8.3

2025-11-25

OAAI

F. Cherifi; L. Cabel; C. Bousrih; E. Volant; F. Dalenc; B. Mery; M. Auvray Kuentz; A. Mailliez; S. Ladoire; A. Tassin de Nonneville; M. Alexandre; L. Benistant; M. Leheurteur; C. Bailleux; M. Debled; J.-S. Frenel; D. Loirat; E. Bastien; Q. Aussedat; F.C. Bidard

Nivolumab in combination with ipilimumab versus capecitabine as post-operative treatment for triple negative breast cancer patients with residual disease after neoadjuvant chemotherapy: a multicentre, randomized, open-label phase II trial – BREASTIMMUNE-03 纳武利尤单抗联合伊匹木单抗与卡培他滨作为新辅助化疗后仍有残留病灶的三阴性乳腺癌患者的术后治疗：一项多中心、随机、开放标签的II期试验——BREASTIMMUNE-03

The Breast

IF0

2025-11-21

OAAI

Olivier Trédan; Delphine Loirat; Sylvie Chabaud; Philippe Toussaint; Thierry Petit; Frédéric Viret; Christelle Levy; Aurélien Robert; Julien Grenier; Laura Mansi; Jean-Philippe Spano; Anne Patsouris; Olfa Derbel; Christelle Jouannaud; Jean Marc Ferrero; Jean Sébastien Frenel; Yann Molin; Louis Doublet; Pierre-Etienne Heudel; Jean-Yves Pierga

Association between molecular classification and overall survival in patients with metastatic endometrial carcinoma: ancillary results of the UTOLA phase II GINECO trial.转移性子宫内膜癌患者中分子分型与总生存期的关联：UTOLA II期GINECO试验的辅助结果。

International Journal of Gynecological Cancer

IF4.7

2025-11-21

PREAI

Guillaume Beinse; Karen Leroy; Pierre-Alexandre Just; Corinne Jeanne; François Cherifi; Alexandra Leary; Olivia Le Saux; Benoît You; Manuel Rodrigues; Laurence Gladieff; Sophie Abadie-Lacourtoisie; Leïla Bengrine Lefevre; Pierre-Emmanuel Brachet; Coriolan Lebreton; Guillaume Meynard; Pierre Fournel; Jean-Sébastien Frenel; Frédéric Selle; Rémy Largillier; Cyril Foa

Blood Sample Preparation for Human Chemical Exposomics: Insights from Large-Scale Applications 人体化学暴露组学的血液样本制备：大规模应用的经验与启示

Environmental Science & Technology

IF11.3

2025-09-30

PREAI

Jade Chaker; Eva Gorrochategui Matas; Cécile Chevrier; Mario Campone; Jean-Sébastien Frenel; Frédéric Bigot; Vincent Bessonneau; Arthur David

Real-world analysis of HER2-ultralow in HR+/HER2– metastatic breast cancer: prevalence and first-line chemotherapy outcomes HR2-ultra-low 在HR+/HER2–转移性乳腺癌中的真实世界分析：患病率及一线化疗疗效

Therapeutic Advances in Medical Oncology

IF4.2

2025-09-28

OAAI

Laurent Mathiot; Olivier Kerdraon; Florent Le Borgne; Véronique Verriele; Anne Patsouris; Marie Robert; Jérôme Chetritt; Delphine Loussouarn; Mario Campone; François Bocquet; Jean-Sébastien Frenel

Real-world treatment patterns and effectiveness after disease progression on CDK4/6 inhibitors for HR-positive/HER2-negative metastatic breast cancer in the ESME-MBC cohort CDK4/6抑制剂治疗后疾病进展的HR阳性/HER2阴性转移性乳腺癌患者中真实世界的治疗模式与疗效：ESME-MBC队列研究

ESMO Open

IF8.3

2025-09-17

PREAI

R. Varnier; D. Pérol; W. Jacot; A. Mailliez; V. Diéras; F. Dalenc; A. Gonçalves; C. Levy; M. Arnedos; J.-S. Frenel; C. Bailleux; V. Massard; E. Brain; B. Sauterey; A.-M. Savoye; L. Bosquet; J.-C. Thery; T. Petit; T. Bachelot; T. Grinda; I. Ray-Coquard

Selective disruption of DNMT1/ELK1 interactions induces DGKI re-expression and promotes temozolomide sensitivity of MGMTmethylated/DGKImethylated glioblastoma 选择性破坏DNMT1/ELK1相互作用可诱导DGKI再表达，并增强MGMT甲基化/DGKI甲基化胶质母细胞瘤对替莫唑胺的敏感性。

Clinical Epigenetics

IF4.4

2025-09-01

OAAI

Jean-Maxime Besson; Amandine Etcheverry; Arulraj Nadaradjane; Gwenola Bougras-Cartron; Marc Aubry; Jean-Sebastien Frenel; Alain Chevanieu; Marie Lopez; Jean Mosser; Pierre-François Cartron

Maintenance olaparib after platinum-based chemotherapy for advanced/metastatic endometrial cancer: GINECO randomized phase IIb UTOLA trial 奥拉帕利维持治疗在铂类为基础化疗后的晚期/转移性子宫内膜癌中的应用：GINECO随机IIb期UTOLA试验

Nature Communications

IF15.7

2025-08-26

OAAI

Florence Joly; Alexandra Leary; Isabelle Ray-Coquard; Bernard Asselain; Manuel Rodrigues; Laurence Gladieff; Guillaume Meynard; Sophie Abadie-Lacourtoisie; Coriolan Lebreton; Leïla Bengrine Lefevre; Pierre Fournel; Rémy Largillier; Frédéric Selle; Jean-Sébastian Frenel; Yolanda Fernandez Diez; Cyril Foa; Philippe Follana; Jérôme Meunier; Michel Fabbro; Anne-Claire Hardy Bessard; Isabelle Cojean-Zelek; Emilie Kaczmarek; Elise Bonnet; Antoine Arnaud; Sophie Roche; Karen Leroy; Pierre-Alexandre Just; Raphaël Leman; Corinne Jeanne; Céline Callens; Benoit You; Jérôme Alexandre

Immune landscape and TAM density in endometrial cancer: implications for immune checkpoint inhibitors efficacy 子宫内膜癌的免疫景观和肿瘤相关巨噬细胞密度：对免疫检查点抑制剂疗效的启示

Therapeutic Advances in Medical Oncology

IF4.2

2025-08-08

OAAI

Olivia Le Saux; Renaud Sabatier; Isabelle Treilleux; Léa-Isabelle Renaud; Pierre-Emmanuel Brachet; Alejandra Martinez; Jean-Sébastien Frenel; Cyril Abdeddaim; Justine Berthet; Sarah Barrin; Amélie Colombe-Vermorel; Laetitia Odeyer; Alexandra Lainé; Christophe Caux; Bertrand Dubois; Isabelle Ray-Coquard

研究方向