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J

James J. Cai

texas a&m university

39H指数
226论文数
5.6K被引数
收录论文 83
发表时间
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Single-cell gene regulatory networks characterize colonic stem and immune cell homeostasis in Nr4a1 knockout mice单细胞基因调控网络表征Nr4a1基因敲除小鼠结肠干细胞和免疫细胞稳态
erriScience
IF4.1
err2026-09-09
err0
errOAAI
errSelim Romero; Shreyan Gupta; Michael L. Salinas; Destiny A. Mullens; Jennifer Goldsby; Yang Y. Fan; Laurie A. Davidson; Jaileen Rivera-Rodriguez; Gus A. Wright; Stephen H. Safe; James J. Cai; Robert S. Chapkin
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High-fat diet remodels plasma membrane rigidity to potentiate colonocyte stemness in mice高脂饮食重塑血浆膜刚度以增强小鼠结肠细胞干细胞特性
errCellular and Molecular Gastroenterology and Hepatology
IF7.4
err2026-09-04
err0
errOAAI
errMichael L. Salinas; Natividad R. Fuentes; Xiaoli Wang; Ellen Ruth Alexander Morris; Yang-Yi Fan; Madison E. Edwards; Xin Yan; Evelyn S. Callaway; Kerstin K. Landrock; James J. Cai; Robert S. Chapkin
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Digit regeneration in mice is stimulated by sequential treatment with FGF2 and BMP2通过FGF2和BMP2的顺序治疗刺激小鼠的手指再生
errNature Communications
IF15.7
err2026-04-17
err0
errOAAI
errLing Yu; Mingquan Yan; Katherine Zimmel Scaturro; Osama Qureshi; Yu-Lieh Lin; Benjamin B. Bartelle; C. Addison Smith; Daniel Osorio Hurtado; James J. Cai; Lindsay A. Dawson; Regina Brunauer; Larry J. Suva; Manjong Han; Connor P. Dolan; Ken Muneoka
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Brewed Coffee and Its Components Act Through Orphan Nuclear Receptor 4A1 (NR4A1)咖啡及其成分通过孤核受体4A1（NR4A1）发挥作用
errNutrients
IF5
err2026-03-10
err0
errOAAI
errAmanuel Hailemariam; Srijana Upadhyay; Arafat Rahman Oany; Wai Ning Tiffany Tsui; Vinod Srivastava; Gargi Sivaram; Kelly Churion; Robert S. Chapkin; Laurie A. Davidson; Shoshana Eitan; James J. Cai; Roger Norton; Stephen Safe
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Modeling spastic paraplegia 4 with corticospinal motor neuron-enriched cortical organoids reveals genotype-phenotype and HDAC6-targetable pathology利用富含皮质脊髓运动神经元的皮质类器官模拟痉挛性截瘫4型，揭示了基因型-表型关联及可被HDAC6靶向的病理机制
errCell Reports
IF6.9
err2026-02-24
err0
errOAAI
errNeha Mohan; Skandha Ramakrishnan; Xiaohuan Sun; Ying Sun; Theresa Connors; Victor Chai; Emanuela Piermarini; Peter W. Baas; James Cai; Mei Liu; Liang Qiang
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Intranasal Human NSC-Derived EVs Therapy Can Restrain Inflammatory Microglial Transcriptome, and NLRP3 and cGAS-STING Signalling, in Aged Hippocampus鼻内注射人NSC衍生的外泌体疗法可抑制衰老海马体中炎症小胶质细胞的转录组、NLRP3和cGAS-STING信号通路
errJournal of Extracellular Vesicles
IF14.5
err2026-02-08
err0
errOAAI
errLeelavathi N. Madhu; Maheedhar Kodali; Shama Rao; Sahithi Attaluri; Raghavendra Upadhya; Goutham Shankar; Bing Shuai; Yogish Somayaji; Shruthi V. Ganesh; Vignesh S. Kumar; Jeswin E. James; Padmashri A. Shetty; Avery LeMaire; Xiaolan Rao; James J Cai; Ashok K. Shetty
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Pesco-vegetarian food components promote colonocyte ferroptosis in preclinical mouse models and a randomized crossover trial in healthy human adultsPesco-vegetarian food components在临床前小鼠模型和健康成人随机交叉试验中促进结肠细胞铁死亡。
errThe Journal of Nutrition
IF0
err2025-12-27
err0
PREAI
errYang-Yi Fan; Michael L. Salinas; Destiny A. Mullens; Laurie A. Davidson; Jennifer S. Goldsby; Ivan V. Ivanov; Arul Jayaraman; James J. Cai; Lisa Levy; Meredith A. Hullar; Sandi L. Navarro; Johanna W. Lampe; Robert S. Chapkin
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Quantum annealing for enhanced feature selection in single-cell RNA sequencing data analysis量子退火在单细胞RNA测序数据分析中用于增强特征选择
errQuantum Machine Intelligence
IF4.4
err2025-12-01
err0
errOAAI
errSelim Romero; Shreyan Gupta; Victoria Gatlin; Robert S. Chapkin; James J. Cai
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LILRB4 regulates circadian disruption-induced mammary tumorigenesis via non-canonical WNT signaling pathwayLILRB4通过非经典WNT信号通路调控昼夜节律紊乱诱导的乳腺肿瘤发生
errOncogene
IF7.3
err2025-10-16
err0
errOAAI
errOlajumoke Ogunlusi; Mrinmoy Sarkar; Kayla Carter; Arhit Chakrabarti; Devon J. Boland; Tristan Nguyen; James Sampson; Christian Nguyen; Danielle Fails; Yava Jones-Hall; Loning Fu; Gus Wright; Da Mi Kim; James J. Cai; Bani Mallick; Alex C. Keene; Jeff R. Jones; Tapasree Roy Sarkar
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FGF8 induces bone and joint regeneration at digit amputation wounds in neonate miceFGF8诱导新生小鼠断指伤口处的骨和关节再生。
errBone
IF3.6
err2025-10-02
err0
PREAI
errLing Yu; Mingquan Yan; Sarah M. Wolff; Joseph D. Knue; Hannah M. Smith; Connor P. Dolan; Ken Muneoka; Selim Romero; James J. Cai; Carissa Yun; Devon J. Boland; Regina Brunauer; Lindsay A. Dawson
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scTenifoldNet and scTenifoldKnk: A package suite for single-cell gene regulatory network construction, comparison, and perturbation analysisscTenifoldNet和scTenifoldKnk：用于单细胞基因调控网络构建、比较和扰动分析的软件包套件
errSTATISTICAL THEORY AND RELATED FIELDS
IF0
err2025-09-01
err0
errOAAI
errZhong, Yan; Osorio, Daniel; Li, Guanxun; Xu, Qian; Yang, Yongjian; Huang, Jianhua Z.; Cai, James J.
err分享
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scPOEM: robust co-embedding of peaks and genes revealing peak-gene regulationscPOEM：峰值和基因的鲁棒共嵌入揭示峰值-基因调控
errBIOINFORMATICS
IF5.4
err2025-09-01
err0
errOAAI
errZhong, Yan; Hou, Yuntong; Yang, Yongjian; Zheng, Xinyue; Cai, James J.
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Biosynthetic rule-guided theoretical chemical space mapping strategy for enhanced analysis of plant metabolomes: application to the geographical profiling of goji berry基于生物合成规则指导的理论化学空间映射策略，用于增强植物代谢组分析：在枸杞地理特征分析中的应用
errScience Bulletin
IF21.1
err2025-04-29
err0
PREAI
errWan-Yang Sun; Zhi-Hui Luo; Jie-Qi Cai; Qian Guo; Guo-Tao Chen; Guo-Dong Chen; Dan Hu; Hai-Guang Gong; Xue Li; Wei Bi; Ying Wang; Kwok-Fai So; Xin-Sheng Yao; Zheng-Qun Zhou; Rong-Rong He; Hao Gao
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Single-cell transcriptomics reveals that human milk feeding shapes neonatal immune cell interleukin signaling pathways in a nonrandomized clinical trial单细胞转录组学揭示，在非随机化临床试验中，母乳喂养塑造了新生儿免疫细胞白介素信号通路。
errThe American Journal of Clinical Nutrition
IF0
err2025-04-26
err0
PREAI
errMichael L Salinas; Bharath Kumar Mulakala; Laurie A Davidson; James J Cai; Sharon M Donovan; Robert S Chapkin; Laxmi Yeruva
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Expression of Prooncogenic Nuclear Receptor 4A (NR4A)-Regulated Genes β1-Integrin and G9a Inhibited by Dual NR4A1/2 Ligands原癌核受体4A (NR4A)-调控基因β1-整合素和G9a的表达受双重NR4A1/2配体的抑制
errINTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
IF4.9
err2025-04-21
err0
errOAAI
errZhang, Lei; Gatlin, Victoria; Gupta, Shreyan; Salinas, Michael L.; Romero, Selim; Cai, James J.; Chapkin, Robert S.; Safe, Stephen
err分享
err收藏
Extracellular vesicles from hiPSC-derived NSCs protect human neurons against Aβ-42 oligomers induced neurodegeneration, mitochondrial dysfunction and tau phosphorylation人源诱导多能干细胞（hiPSC）来源的神经干细胞（NSCs）分泌的外泌体能够保护人神经元免受Aβ-42寡聚体诱导的神经退行性变、线粒体功能障碍和tau蛋白磷酸化的影响。
errSTEM CELL RESEARCH & THERAPY
IF7.3
err2025-04-18
err1
errOAAI
errRao, Shama; Madhu, Leelavathi N.; Babu, Roshni Sara; Shankar, Goutham; Kotian, Sanya; Nagarajan, Advaidhaa; Upadhya, Raghavendra; Narvekar, Esha; Cai, James J.; Shetty, Ashok K.
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Exploring cell-to-cell variability and functional insights through differentially variable gene analysis
errNPJ SYSTEMS BIOLOGY AND APPLICATIONS
IF3.5
err2025-03-20
err0
errOAAI
errGatlin, Victoria; Gupta, Shreyan; Romero, Selim; Chapkin, Robert S.; Cai, James J.
err分享
err收藏
Machine learning identifies clinical tumor mutation landscape pathways of resistance to checkpoint inhibitor therapy in NSCLC机器学习识别NSCLC中针对检查点抑制剂疗法的临床肿瘤突变景观耐药通路
errJOURNAL FOR IMMUNOTHERAPY OF CANCER
IF10.6
err2025-03-03
err1
errOAAI
errFomin, Vitalay; So, WeiQing Venus; Barbieri, Richard Alex; Hiller-Bittrolff, Kenley; Koletou, Elina; Tu, Tiffany; Gomes, Bruno; Cai, James
err分享
err收藏
Single-Cell RNA Sequencing Reveals Extensive Heterogeneity and Unique Gene Trajectories in Non-Transformed and Transformed Human Lung Epithelial Cells: Insights into the Role of LncRNAs in Tumor Heterogeneity单细胞RNA测序揭示非转化和转化人肺上皮细胞中广泛的异质性和独特的基因轨迹：对长链非编码RNA在肿瘤异质性中作用的见解
errINTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
IF4.9
err2025-02-16
err1
errOAAI
errMoeng, Sokviseth; Chamorro-Parejo, Andres D.; Jeon, Minsun S.; Cai, James J.; Ramos, Kenneth S.
err分享
err收藏
Gene function revealed at the moment of sitochastic gene silencing
errCOMMUNICATIONS BIOLOGY
IF5.1
err2025-01-19
err0
errOAAI
errGupta, Shreyan; Cai, James J.
err分享
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研究方向

暂无研究方向
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