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H

Hirokazu Hirai

initiative for advanced research

49H指数
346论文数
8.8K被引数
收录论文 70
发表时间
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A compact GAD67 promoter enables inhibitory neuron-targeted AAV gene therapy for seizure suppression紧凑型GAD67启动子实现靶向抑制性神经元AAV基因疗法以抑制癫痫发作
errMolecular Therapy
IF12
err2026-06-25
err0
errOAAI
errYuuki Fukai; Ayumu Konno; Nobutake Hosoi; Karin Miyakawa; Ryosuke Kaneko; Hirokazu Hirai
err分享
err收藏
Establishment of spinocerebellar ataxia type 34 model mice accompanied by early glial activation and degeneration of cerebellar neurons建立伴有早期胶质细胞活化和小脑神经元变性的脊髓小脑共济失调34型模型小鼠
errJournal of Pharmacological Sciences
IF2.9
err2026-04-24
err0
errOAAI
errYuri Morikawa-Yujiri; Kensuke Motomura; Ayumu Konno; Natsuko Hitora-Imamura; Yuki Kurauchi; Satohiro Masuda; Hirokazu Hirai; Hiroshi Katsuki; Takahiro Seki
err分享
err收藏
Age-Progressive Synaptic and Axonal Dysregulation Induced by Purkinje Cell-Targeted AAV Expression of SCA14 PKCγ in Mice由靶向普肯耶细胞的AAV表达SCA14 PKCγ诱导的小鼠年龄进展性突触和轴突功能失调
errJOURNAL OF NEUROCHEMISTRY
IF4
err2025-11-01
err0
PREAI
errAdachi, Naoko; Koganemaru, Izumi; Wanying, Feng; Matsushita, Naoya; Nakayama, Tomoyoshi; Seki, Takahiro; Konno, Ayumu; Hirai, Hirokazu; Saito, Naoaki; Ueyama, Takehiko
err分享
err收藏
Blood-brain barrier-penetrant AAV vectors for cell type-specific gene expression in the mouse brain血脑屏障穿透性AAV载体用于小鼠脑内细胞类型特异性基因表达
errANATOMICAL SCIENCE INTERNATIONAL
IF1.7
err2025-09-01
err0
PREAI
errHirai, Hirokazu; Iwazaki, Shu; Hoshino, Reona; Maruyama, Tokuzo; Aoki, Ryo; Radhiyanti, Putri T.; Konno, Ayumu
err分享
err收藏
AAV vectors for specific and efficient gene expression in microglia
errCell Reports Methods
IF4.5
err2025-07-30
err0
errOAAI
errRyo Aoki; Ayumu Konno; Nobutake Hosoi; Hayato Kawabata; Hirokazu Hirai
err分享
err收藏
A hyper-activatable CAMK2A variant associated with intellectual disability causes exaggerated long-term potentiation and learning impairments与智力障碍相关的超活化CAMK2A变体导致长时程增强过度增强和学习障碍
errTRANSLATIONAL PSYCHIATRY
IF6.2
err2025-03-26
err0
errOAAI
errPan, Miao; Liu, Pin-Wu; Ozawa, Yukihiro; Arima-Yoshida, Fumiko; Dong, Geyao; Sawahata, Masahito; Mori, Daisuke; Nagase, Masashi; Fujii, Hajime; Ueda, Shuhei; Yabuuchi, Yurie; Liu, Xinzi; Narita, Hajime; Konno, Ayumu; Hirai, Hirokazu; Ozaki, Norio; Yamada, Kiyofumi; Kidokoro, Hiroyuki; Bito, Haruhiko; Mizoguchi, Hiroyuki; M. Watabe, Ayako; Horigane, Shin-ichiro; Takemoto-Kimura, Sayaka
err分享
err收藏
Critical factors for flow cytometry analysis of the brain
errFEBS JOURNAL
IF4.2
err2025-03-14
err0
errOAAI
errSadakata, Mizuki; Konno, Ayumu; Takase, Akinori; Kasamatsu, Tetsuhiro; Iijima, Takatoshi; Hirai, Hirokazu; Sadakata, Tetsushi
err分享
err收藏
Contribution of thyrotropin-releasing hormone to cerebellar long-term depression and motor learning (vol 12, 490, 2018)
errFRONTIERS IN CELLULAR NEUROSCIENCE
IF4
err2024-09-26
err0
errOAAI
errWatanave, Masashi; Matsuzaki, Yasunori; Nakajima, Yasuyo; Ozawa, Atsushi; Yamada, Masanobu; Hirai, Hirokazu
err分享
err收藏
Nurr1 overexpression in the primary motor cortex alleviates motor dysfunction induced by intracerebral hemorrhage in the striatum in mice
errNEUROTHERAPEUTICS
IF6.9
err2024-07-01
err0
errOAAI
errKinoshita, Keita; Motomura, Kensuke; Ushida, Keisuke; Hirata, Yuma; Konno, Ayumu; Hirai, Hirokazu; Kotani, Shunsuke; Hitora-Imamura, Natsuko; Kurauchi, Yuki; Seki, Takahiro; Katsuki, Hiroshi
err分享
err收藏
Protein kinase Cγ negatively regulates the intrinsic excitability in zebrin-negative cerebellar Purkinje cells
errFRONTIERS IN CELLULAR NEUROSCIENCE
IF4
err2024-02-16
err0
errOAAI
errWatanave, Masashi; Kawachi, Mika; Konno, Ayumu; Aoki, Ryo; Fukai, Yuuki; Matsuzaki, Yasunori; Kaneko, Ryosuke; Hirai, Hirokazu
err分享
err收藏
Excitatory subtypes of the lateral amygdala neurons are differentially involved in regulation of synaptic plasticity and excitation/inhibition balance in aversive learning in mice
errFRONTIERS IN CELLULAR NEUROSCIENCE
IF4
err2023-12-14
err0
errOAAI
errMorishima, Mieko; Matsumura, Sohta; Tohyama, Suguru; Nagashima, Takashi; Konno, Ayumu; Hirai, Hirokazu; Watabe, Ayako M.
err分享
err收藏
State-dependent modulation of positive and negative affective valences by a parabrachial nucleus-to-ventral tegmental area pathway in mice
errFRONTIERS IN NEURAL CIRCUITS
IF3
err2023-11-29
err0
errOAAI
errNagashima, Takashi; Mikami, Kaori; Tohyama, Suguru; Konno, Ayumu; Hirai, Hirokazu; Watabe, Ayako M.
err分享
err收藏
Interstitial-fluid shear stresses induced by vertically oscillating head motion lower blood pressure in hypertensive rats and humans (Jul, 10.1038/s41551-023-01061-x, 2023)
errNATURE BIOMEDICAL ENGINEERING
IF26.6
err2023-11-07
err0
errOAAI
errMurase, Shuhei; Sakitani, Naoyoshi; Maekawa, Takahiro; Yoshino, Daisuke; Takano, Kouji; Konno, Ayumu; Hirai, Hirokazu; Saito, Taku; Tanaka, Sakae; Shinohara, Keisuke; Kishi, Takuya; Yoshikawa, Yuki; Sakai, Takamasa; Ayaori, Makoto; Inanami, Hirohiko; Tomiyasu, Koji; Takashima, Atsushi; Ogata, Toru; Tsuchimochi, Hirotsugu; Sato, Shinya; Saito, Shigeyoshi; Yoshino, Kohzoh; Matsuura, Yuiko; Funamoto, Kenichi; Ochi, Hiroki; Shinohara, Masahiro; Nagao, Motoshi; Sawada, Yasuhiro
err分享
err收藏
Interstitial-fluid shear stresses induced by vertically oscillating head motion lower blood pressure in hypertensive rats and humans
errNATURE BIOMEDICAL ENGINEERING
IF26.6
err2023-07-06
err5
errOAAI
errMurase, Shuhei; Sakitani, Naoyoshi; Maekawa, Takahiro; Yoshino, Daisuke; Takano, Kouji; Konno, Ayumu; Hirai, Hirokazu; Saito, Taku; Tanaka, Sakae; Shinohara, Keisuke; Kishi, Takuya; Yoshikawa, Yuki; Sakai, Takamasa; Ayaori, Makoto; Inanami, Hirohiko; Tomiyasu, Koji; Takashima, Atsushi; Ogata, Toru; Tsuchimochi, Hirotsugu; Sato, Shinya; Saito, Shigeyoshi; Yoshino, Kohzoh; Matsuura, Yuiko; Funamoto, Kenichi; Ochi, Hiroki; Shinohara, Masahiro; Nagao, Motoshi; Sawada, Yasuhiro
err分享
err收藏
Interaction between Teneurin-2 and microtubules via EB proteins provides a platform for GABAA receptor exocytosis
errELIFE
IF0
err2023-06-05
err2
errOAAI
errIchinose, Sotaro; Susuki, Yoshihiro; Hosoi, Nobutake; Kaneko, Ryosuke; Ebihara, Mizuho; Hirai, Hirokazu; Iwasaki, Hirohide; Ori-McKenney, Kassandra M.
err分享
err收藏
CD3 and immunoglobulin G Fc receptor regulate cerebellar functions
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err51
errOAAI
errNakamura, Kazuhiro; Hirai, Hirokazu; Torashima, Takashi; Miyazaki, Taisuke; Tsurui, Hiromichi; Xiu, Yan; Ohtsuji, Mareki; Lin, Qing Shun; Tsukamoto, Kazuyuki; Nishimura, Hiroyuki; Ono, Masao; Watanabe, Masahiko; Hirose, Sachiko
err分享
err收藏
Shp2 in Forebrain Neurons Regulates Synaptic Plasticity, Locomotion, and Memory Formation in Mice
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-20
err33
errOAAI
errKusakari, Shinya; Saitow, Fumihito; Ago, Yukio; Shibasaki, Koji; Sato-Hashimoto, Miho; Matsuzaki, Yasunori; Kotani, Takenori; Murata, Yoji; Hirai, Hirokazu; Matsuda, Toshio; Suzuki, Hidenori; Matozaki, Takashi; Ohnishi, Hiroshi
err分享
err收藏
DOPAnization of tyrosine in α-synuclein by tyrosine hydroxylase leads to the formation of oligomers
errNATURE COMMUNICATIONS
IF15.7
err2022-11-12
err11
errOAAI
errJin, Mingyue; Matsumoto, Sakiko; Ayaki, Takashi; Yamakado, Hodaka; Taguchi, Tomoyuki; Togawa, Natsuko; Konno, Ayumu; Hirai, Hirokazu; Nakajima, Hiroshi; Komai, Shoji; Ishida, Ryuichi; Chiba, Syuhei; Takahashi, Ryosuke; Takao, Toshifumi; Hirotsune, Shinji
err分享
err收藏
Development of microglia-targeting adeno-associated viral vectors as tools to study microglial behavior in vivo
errCOMMUNICATIONS BIOLOGY
IF5.1
err2022-11-11
err23
errOAAI
errOkada, Yukihiro; Hosoi, Nobutake; Matsuzaki, Yasunori; Fukai, Yuuki; Hiraga, Akito; Nakai, Junichi; Nitta, Keisuke; Shinohara, Yoichiro; Konno, Ayumu; Hirai, Hirokazu
err分享
err收藏
Long-term depression-inductive stimulation causes long-term potentiation in mouse Purkinje cells with a mutant thyroid hormone receptor
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2022-11-02
err8
errOAAI
errNinomiya, Ayane; Amano, Izuki; Kokubo, Michifumi; Takatsuru, Yusuke; Ishii, Sumiyasu; Hirai, Hirokazu; Hosoi, Nobutake; Koibuchi, Noriyuki
err分享
err收藏

研究方向

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合作学者
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