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P

Paolo L. Manfredi

mggm therapeutics

22H指数
102论文数
2.4K被引数
收录论文 41
发表时间
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Pharmacokinetics and safety of a modified-release psilocybin formulation: A SAD Phase I trial in normal-weight and overweight/obese participants一种改良释放型裸盖菇素制剂的药代动力学与安全性：一项在正常体重和超重/肥胖受试者中进行的SAD I期试验
errBritish Journal of Clinical Pharmacology
IF3
err2026-09-22
err0
errOAAI
errAnna Signor; Stefano Comai; Gianfranco Pasut; Franco Folli; Marco Gentilucci; Negar Gharavi; Sofia Raitsin; Thuy Van Nguyen; Marco Pappagallo; Andrea Mattarei; Paolo L. Manfredi; Sara De Martin
err分享
err收藏
Design; Synthesis; and Pharmacokinetic Profiling of Fluorinated Reversible N-Alkyl Carbamate Derivatives of Psilocin for Sub-Hallucinogenic Brain Exposure
errJournal of Medicinal Chemistry
IF6.8
err2026-01-26
err0
errOAAI
errMarco Banzato; Martina Colognesi; Lorena Lucatello; Stefano Comai; Gianfranco Pasut; Francesca Capolongo; Laura Orian; Lucia Biasutto; Anna Signor; Daniela Gabbia; Paolo L. Manfredi; Sara De Martin; Andrea Mattarei
err分享
err收藏
Esmethadone (REL-1017) in Patients With Major Depressive Disorder and Antidepressant Tachyphylaxis: An Exploratory Post Hoc Analysis From a Phase 3 Randomized Controlled TrialEsmethadone (REL-1017) 在伴有抗抑郁药快速耐受性的重度抑郁症患者中的探索性事后分析：一项来自3期随机对照试验的研究
errJournal of Clinical Psychiatry
IF4.6
err2025-12-01
err0
PREAI
errGuidetti, Clotilde; Papakostas, George I.; Pani, Luca; De Martin, Sara; Serra, Giulia; Apicella, Massimo; Kroger, Cornelia; Champasa, Paggard; Comai, Stefano; Mattarei, Andrea; Folli, Franco; Pappagallo, Marco; Manfredi, Paolo L.; Fava, Maurizio
err分享
err收藏
Reasons for Maintaining the Classification of Esmethadone as an Investigational Uncompetitive NMDAR Antagonist Rapid Antidepressant: Reply to Ferré and Michaelides维持将Esmethadone归类为 investigational uncompetitive NMDAR antagonist rapid antidepressant 的原因：回复Ferré和Michaelides
errJournal of Clinical Psychiatry
IF4.6
err2025-12-01
err0
PREAI
errDe Martin, Sara; Comai, Stefano; Mattarei, Andrea; Kosten, Thomas R.; Vocci, Frank J.; Gorodetzky, Charles W.; Pappagallo, Marco; Manfredi, Paolo L.
err分享
err收藏
A novel artificial intelligence-based methodology to predict non-specific response to treatment一种基于人工智能的新型方法学，用于预测对治疗的非特异性反应
errPSYCHIATRY RESEARCH
IF3.9
err2025-06-01
err0
PREAI
errGuidetti, Clotilde; Fava, Maurizio; Manfredi, Paolo L.; Pappagallo, Marco; Gomeni, Roberto
err分享
err收藏
ANXIOLYTIC- AND PROCOGNITIVE-LIKE EFFECTS OF A 30-DAY CHRONIC TREATMENT WITH A LOW NON-PSYCHEDELIC DOSE OF PSILOCYBIN IN C57BL/6J MICE30天慢性低剂量非致幻性裸盖菇素处理对C57BL/6J小鼠的镇静和促认知样作用
errINTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
IF3.7
err2025-02-12
err0
errOAAI
errNasini, Sofia; Tidei, Sara; Barzon, Benedetta; De Martin, Sara; Banzato, Marco; Mattarei, Andrea; Folli, Franco; Pappagallo, Marco; Manfredi, Paolo L.; Comai, Stefano
err分享
err收藏
N-methyl-D-aspartate Receptors and Depression: Linking Psychopharmacology, Pathology and Physiology in a Unifying Hypothesis for the Epigenetic Code of Neural Plasticity
errPHARMACEUTICALS
IF4.8
err2024-11-30
err2
errOAAI
errComai, Stefano; De Martin, Sara; Mattarei, Andrea; Guidetti, Clotilde; Pappagallo, Marco; Folli, Franco; Alimonti, Andrea; Manfredi, Paolo L.
err分享
err收藏
Letter to the Editor regarding 'Unique pharmacodynamic properties and low abuse liability of the μ-opioid receptor ligand (S)-methadone'
errMOLECULAR PSYCHIATRY
IF10.1
err2024-05-28
err2
errOAAI
errPappagallo, Marco; Kosten, Thomas R.; Gorodetzky, Charles W.; Vocci, Frank J.; Sapienza, Frank L.; De Martin, Sara; Comai, Stefano; Mattarei, Andrea; Inturrisi, Charles E.; Manfredi, Paolo L.
err分享
err收藏
Non-psychedelic doses of psilocybin as a novel therapeutic approach for MASLD
errDIGESTIVE AND LIVER DISEASE
IF3.8
err2024-02-01
err0
PREAI
errDe Martin, S.; Gabbia, D.; Colognesi, M.; Rinaldi, A.; Cascione, L.; Zanotto, I.; Sayaf, K.; Comai, S.; Mattarei, A.; Banzato, M.; Pasut, G.; Folli, F.; Centofanti, L.; Traversa, S.; Pappagallo, M.; Manfredi, P. L.
err分享
err收藏
The novel uncompetitive NMDA receptor antagonist esmethadone (REL-1017) has no meaningful abuse potential in recreational drug users
errTRANSLATIONAL PSYCHIATRY
IF6.2
err2023-06-07
err7
errOAAI
errShram, Megan J. J.; Henningfield, Jack E. E.; Apseloff, Glen; Gorodetzky, Charles W. W.; De Martin, Sara; Vocci, Frank L. L.; Sapienza, Frank L. L.; Kosten, Thomas R. R.; Huston, Jeff; Buchhalter, August; Ashworth, Judy; Lanier, Ryan; Folli, Franco; Mattarei, Andrea; Guidetti, Clotilde; Comai, Stefano; O'Gorman, Cedric; Traversa, Sergio; Inturrisi, Charles E. E.; Manfredi, Paolo L. L.; Pappagallo, Marco
err分享
err收藏
Esmethadone-HCl (REL-1017): a promising rapid antidepressant
errEUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE
IF3.7
err2023-03-08
err20
errOAAI
errFava, Maurizio; Stahl, Stephen M. M.; De Martin, Sara; Mattarei, Andrea; Bettini, Ezio; Comai, Stefano; Alimonti, Andrea; Bifari, Francesco; Pani, Luca; Folli, Franco; Guidetti, Clotilde; Furlan, Alberto; Sgrignani, Jacopo; Locatelli, Patrizia; Cavalli, Andrea; O'Gorman, Cedric; Traversa, Sergio; Inturrisi, Charles E. E.; Pappagallo, Marco; Manfredi, Paolo L. L.
err分享
err收藏
Pharmacological Comparative Characterization of REL-1017 (Esmethadone-HCl) and Other NMDAR Channel Blockers in Human Heterodimeric N-Methyl-D-Aspartate Receptors
errPHARMACEUTICALS
IF4.8
err2022-08-13
err23
errOAAI
errBettini, Ezio; Stahl, Stephen M.; De Martin, Sara; Mattarei, Andrea; Sgrignani, Jacopo; Carignani, Corrado; Nola, Selena; Locatelli, Patrizia; Pappagallo, Marco; Inturrisi, Charles E.; Bifari, Francesco; Cavalli, Andrea; Alimonti, Andrea; Pani, Luca; Fava, Maurizio; Traversa, Sergio; Folli, Franco; Manfredi, Paolo L.
err分享
err收藏
The N-Methyl-D-Aspartate Receptor Blocker REL-1017 (Esmethadone) Reduces Calcium Influx Induced by Glutamate, Quinolinic Acid, and Gentamicin
errPHARMACEUTICALS
IF4.8
err2022-07-17
err11
errOAAI
errBettini, Ezio; De Martin, Sara; Mattarei, Andrea; Pappagallo, Marco; Stahl, Stephen M.; Bifari, Francesco; Inturrisi, Charles E.; Folli, Franco; Traversa, Sergio; Manfredi, Paolo L.
err分享
err收藏
REL-1017 (esmethadone; d-methadone) does not cause reinforcing effect, physical dependence and withdrawal signs in Sprague Dawley rats
errSCIENTIFIC REPORTS
IF3.9
err2022-07-06
err9
errOAAI
errHenningfield, Jack; Gauvin, David; Bifari, Francesco; Fant, Reginald; Shram, Megan; Buchhalter, August; Ashworth, Judy; Lanier, Ryan; Pappagallo, Marco; Inturrisi, Charles; Folli, Franco; Traversa, Sergio; Manfredi, Paolo L.
err分享
err收藏
REL-1017 (Esmethadone) as Adjunctive Treatment in Patients With Major Depressive Disorder: A Phase 2a Randomized Double-Blind Trial
errAMERICAN JOURNAL OF PSYCHIATRY
IF14.7
err2022-02-01
err60
PREAI
errFava, Maurizio; Stahl, Stephen; Pani, Luca; De Martin, Sara; Pappagallo, Marco; Guidetti, Clotilde; Alimonti, Andrea; Bettini, Ezio; Mangano, Richard M.; Wessel, Thomas; de Somer, Marc; Caron, Judy; Vitolo, Ottavio V.; DiGuglielmo, Gina R.; Gilbert, Adam; Mehta, Hiren; Kearney, Morgan; Mattarei, Andrea; Gentilucci, Marco; Folli, Franco; Traversa, Sergio; Inturrisi, Charles E.; Manfredi, Paolo L.
err分享
err收藏
Comment on Novel Glutamatergic Modulators for the Treatment of Mood Disorders: Current Status
errCNS DRUGS
IF7.4
err2022-01-11
err3
errOAAI
errPappagallo, Marco; Inturrisi, Charles E.; Manfredi, Paolo L.
err分享
err收藏
REL-1017 (esmethadone) did not produce initial or cumulative neurotoxic effects or other evidence of damage to cortical neurons
errFASEB JOURNAL
IF4.2
err2021-05-14
err0
errOAAI
errPappagallo, Marco; Bifari, Francesco; Bleavins, Michael; Folli, Franco; Manfredi, Paolo
err分享
err收藏
A pilot trial of intravenous pamidronate for chronic low back pain
errPAIN
IF5.5
err2014-01-01
err14
errOAAI
errPappagallo, Marco; Breuer, Brenda; Lin, Hung-Mo; Moberly, James B.; Tai, Julia; Noto, Christopher; Sanchez, Angela; Manfredi, Paolo L.
err分享
err收藏
QTc interval prolongation associated with intravenous methadone
errPAIN
IF5.5
err2003-10-01
err163
PREAI
errKornick, CA; Kilborn, MJ; Santiago-Palma, J; Schulman, G; Thaler, HT; Keefe, DL; Katchman, AN; Pezzullo, JC; Ebert, SN; Woosley, RL; Payne, R; Manfredi, PL
err分享
err收藏
Parenteral methadone: An essential medication for the treatment of pain
errJOURNAL OF PAIN AND SYMPTOM MANAGEMENT
IF3.5
err2003-08-01
err10
errOAAI
errManfredi, PL; Foley, KM; Payne, R; Houde, R; Inturrisi, CE
err分享
err收藏

研究方向

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合作学者
合作期刊
M
Maurizio Fava
H 指数: 137 · 论文数: 1.2K
P
Peter C. O’Brien
H 指数: 117 · 论文数: 572
M
M. Pappagallo
H 指数: 94 · 论文数: 826
T
Thomas R. Kosten
H 指数: 93 · 论文数: 796
S
Stephen D. Weigand
H 指数: 92 · 论文数: 354
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