Clélia Akiko Hiruma-Lima

Universidade Estadual Paulista

46H指数

179论文数

5.7K被引数

收录论文 34

发表时间

The methanolic extract of Byrsonima intermedia mitigates colonic injury in experimental colitis through redox restoration, cytokine modulation, and tissue repair 甲醇提取的Byrsonima intermedia通过氧化还原恢复、细胞因子调节和组织修复减轻实验性结肠炎中的结肠损伤

Inflammopharmacology

IF5.3

2026-07-14

OAAI

Karla Stella Figueiredo Romano; Felipe Leonardo Fagundes; Quélita Cristina Pereira; Maycon Tavares Emílio-Silva; Larissa Lucena Périco; Vinicius Peixoto Rodrigues; Gabriela Bueno; Mateus Magami Yoshitani; Giovana Pacciulli Pereira; José Aires Pereira; Carlos Augusto Real Martinez; Alessandra Gambero; Clélia Akiko Hiruma-Lima; Raquel de Cássia dos Santos

Early-life cardiovascular programming by maternal protein restriction: Electrophysiological, structural, and molecular alterations in female rats 母体蛋白质限制对雌性大鼠早期生命心血管编程的影响：电生理学、结构和分子改变

Experimental Cell Research

IF3.5

2026-07-01

PREAI

Gomes, Luisa Correia; Fioretto, Matheus Naia; Lemos, Lucas Sobrinho; Barata, Luisa Annibal; Maciel, Flavia Alessandra; Ribeiro, Isabelle Tenori; de Abreu, Ana Luiza Silva; Portela, Luiz Marcos Frediani; Bravo, Isabella Lopes; Stoppa, Erick Guilherme; Willmann, Raffael Greggio; Emilio-Silva, Maycon Tavares; Lima, Clelia Akiko Hiruma; Miranda, Jose Ricardo de Arruda; Scarano, Wellerson Rodrigo; Justulin, Luis Antonio

Citral exerts a more pronounced antinociceptive effect in obese adult male C57BL/6J mice mediated through the CB2 receptor 柠檬醛通过CB2受体在肥胖成年雄性C57BL/6J小鼠中表现出更显著的镇痛作用

European Journal of Pharmacology

IF4.7

2026-05-04

OAAI

Felipe Lima Dario; Maria Luiza Alves Aquino; Maycon Tavares Emílio-Silva; Felipe Leonardo Fagundes; Laura Vitória Fortunato de Oliveira; Isabela Galende Guidolin; Mariana Moraes Fioravanti; Renata Assunção; Vinícius Peixoto Rodrigues; Gabriela Bueno; Catarine Massucato Nishijima; Clelia Akiko Hiruma-Lima

Citral impairs intestinal changes caused by ulcerative colitis through modulation of antioxidant, anti-inflammatory and healing activities 香叶醇通过调节抗氧化、抗炎和愈合活性来抑制溃疡性结肠炎引起的肠道变化。

Inflammopharmacology

IF5.3

2025-12-03

PREAI

Maycon T. Emílio-Silva; Vinícius P. Rodrigues; Antonio J. Ruiz-Malagon; Isabela G. Guidolin; Felipe L. Dario; Mariana M. Fioravanti; Alba Rodriguez-Nogales; Julio Gálvez; Clelia A. Hiruma-Lima

The Anthocyanidins Malvidin and Cyanidin Alleviate Irinotecan-Triggered Intestinal Mucositis by Modulating Oxidative Stress and Cytokine Release 矢车菊素和飞燕草素通过调节氧化应激和细胞因子释放来缓解伊立替康诱导的肠道黏膜炎

International Journal of Molecular Sciences 2025, Vol. 26, Page 10747

IF4.9

2025-11-05

OAAI

Giovana Filócomo Machado; Quélita Cristina Pereira; Felipe Leonardo Fagundes; Maycon Tavares Emílio-Silva; Vinícius Peixoto Rodrigues; Mariana de Almeida Patiño; Giulia Izzo Jorge; José Aires Pereira; Carlos Augusto Real Martinez; Clélia Akiko Hiruma-Lima; Raquel de Cássia dos Santos

Maternal Protein Restriction promotes Cardiac Disorders by Disrupting Heart Developmental Morphophysiology in Young Male Offspring Rats 母体蛋白质限制通过破坏幼年雄性大鼠后代心脏发育的形态生理学而促进心脏疾病

Experimental Cell Research

IF3.5

2025-10-15

PREAI

Lucas Sobrinho Lemos; Matheus Naia Fioretto; Isabelle Tenori Ribeiro; Luísa Annibal Barata; Flávia Alessandra Maciel; Felipe Leonardo Fagundes; Renato Mattos; Luiz Marcos Frediani Portela; João Miguel Barboza; Beatriz Souza de Oliveira; Keila Emílio de Almeida; Sérgio Alexandre Alcantara dos Santos; Clélia Akiko Hiruma Lima; José Ricardo de Arruda Miranda; Elena Zambrano; Luis Antonio Justulin

Maternal protein restriction compromises hepatic phenotype and antioxidant defense in postweaning male rats, while females exhibit resilience 母体蛋白质限制会损害断奶后雄性大鼠的肝脏表型及抗氧化防御能力，而雌性则表现出抗性。

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

IF2.2

2025-06-01

PREAI

Franzolin, Andre Matheus Leandro; Fioretto, Matheus Naia; Ribeiro, Isabelle Tenori; Maciel, Flavia Alessandra; Barata, Luisa Annibal; Vitali, Pedro Menchini; Magosso, Natalia; Fagundes, Felipe Leonardo; Emilio-Silva, Maycon Tavares; Lima, Clelia Akiko Hiruma; Scarano, Wellerson Rodrigo; Justulin, Luis Antonio

Citral protects against metabolic endotoxemia, and systemic disorders caused by high-fat diet-induced obesity via intestinal modulation 柠檬醛通过肠道调节可保护机体免受高脂饮食诱导肥胖引起的代谢性内毒素血症及系统性紊乱。

FRONTIERS IN PHARMACOLOGY

IF4.8

2025-04-07

OAAI

Emilio-Silva, Maycon Tavares; Rodrigues, Vinicius Peixoto; Fioravanti, Mariana Moraes; Ruiz-Malagon, Antonio Jesus; Fioretto, Matheus Naia; Raimundo, Priscila Romano; Ohara, Rie; Assuncao, Renata; Bueno, Gabriela; Dario, Felipe Lima; Justulin, Luis Antonio; Rodriguez-Nogales, Alba; da Rocha, Lucia Regina Machado; Galvez, Julio; Hiruma-Lima, Clelia Akiko

Maternal protein restriction and postnatal sugar consumption increases inflammatory response and deregulates metabolic pathways in the liver of male offspring rats with aging

MOLECULAR AND CELLULAR ENDOCRINOLOGY

IF3.6

2025-04-01

PREAI

Ribeiro, Isabelle Tenori; Fioretto, Matheus Naia; dos Santos, Sergio Alexandre Alcantara; Alvarez, Marcus Vinicius Niz; Portela, Luiz Marcos Frediani; Mattos, Renato; Sebastian, Hecttor Baptista; Vitali, Pedro Menchini; Seiva, Fabio Rodrigues Ferreira; Barbisan, Luis Fernando; Lima, Clelia Akiko Hiruma; Damasceno, Debora Cristina; Zambrano, Elena; Justulin, Luis Antonio

Maternal protein restriction impairs intestinal morphophysiology and antioxidant system in young male offspring rats

EXPERIMENTAL CELL RESEARCH

IF3.5

2025-03-01

PREAI

dos Santos, Isabela Baptista Leal; Fioretto, Matheus Naia; Jorge, Miguel Silingardi; Barata, Luisa Annibal; Ribeiro, Isabelle Tenori; Franzolin, Andre Matheus Leandro; Stoppa, Erick Guilherme; Mattos, Renato; Portela, Luiz Marcos Frediane; Silva, Maycon Tavares Emilio; dos Santos, Sergio Alexandre Alcantara; Miranda, Jose Ricardo de Arruda; Lima, Clelia Akiko Hiruma; Justulin, Luis Antonio

Long-term effects of maternal protein restriction on adrenal proteomic profile and steroidogenesis in male offspring rats

CELLULAR SIGNALLING

IF3.7

2025-03-01

PREAI

Fioretto, Matheus Naia; Barata, Luisa Annibal; Felipe, Vinicius Alexandre de Andrade; dos Santos, Sergio Alexandre Alcantara; Maciel, Flavia Alessandra; Ribeiro, Isabelle Tenori; Mattos, Renato; Baptista, Hecttor Sebastian; Bueno, Gabriela; Fagundes, Felipe Leonardo; Portela, Luiz Marcos Frediane; Scarano, Wellerson Rodrigo; Seiva, Fabio Rodrigues Ferreira; Lima, Clelia Akiko Hiruma; Justulin, Luis Antonio

Increased oxidative stress and cancer biomarkers in the ventral prostate of older rats submitted to maternal malnutrition

MOLECULAR AND CELLULAR ENDOCRINOLOGY

IF3.6

2021-03-01

PREAI

Portela, Luiz M. F.; Santos, Sergio A. A.; Constantino, Flavia B.; Camargo, Ana C. L.; Colombelli, Ketlin T.; Fioretto, Matheus N.; Barquilha, Caroline N.; Perico, Larissa L.; Hiruma-Lima, Clelia A.; Scarano, Wellerson R.; Zambrano, Elena; Justulin, Luis A.

Intestinal Anti-Inflammatory Activity of Terpenes in Experimental Models (2010-2020): A Review

MOLECULES

IF4.6

2020-11-20

OAAI

Araruna, Maria Elaine; Serafim, Catarina; Alves Junior, Edvaldo; Hiruma-Lima, Clelia; Diniz, Margareth; Batista, Leonia

A Review of the Role of Flavonoids in Peptic Ulcer (2010-2020)黄酮类化合物在消化性溃疡中的作用综述 (2010-2020)

MOLECULES

IF4.6

2020-11-20

OAAI

Serafim, Catarina; Araruna, Maria Elaine; Junior, Edvaldo Alves; Diniz, Margareth; Hiruma-Lima, Clelia; Batista, Leonia

Organic Selenium Reaches the Central Nervous System and Downmodulates Local Inflammation: A Complementary Therapy for Multiple Sclerosis?有机硒到达中枢神经系统并下调局部炎症: 多发性硬化症的补充疗法？

FRONTIERS IN IMMUNOLOGY

IF5.9

2020-10-30

OAAI

de Toledo, Juliana Helena dos Santos; Fraga-Silva, Thais Fernanda de Campos; Borim, Patricia Aparecida; de Oliveira, Larissa Ragozo Cardoso; Oliveira, Evelyn da Silva; Perico, Larissa Lucena; Hiruma-Lima, Clelia Akiko; de Souza, Adriana Aparecida Lopes; de Oliveira, Carlos Alberto Ferreira; Padilha, Pedro de Magalhaes; Pinatto-Botelho, Marcos Felipe; dos Santos, Alcindo Aparecido; Sartori, Alexandrina; Zorzella-Pezavento, Sofia Fernanda Goncalves

Byrsonima intermedia A. Juss partitions promote gastroprotection against peptic ulcers and improve healing through antioxidant and anti-inflammatory activities

BIOMEDICINE & PHARMACOTHERAPY

IF7.5

2019-03-01

OAAI

dos Santos, Raquel de Cassia; Bonamin, Flavia; Perico, Larissa Lucena; Peixoto Rodrigues, Vinicius; Zanatta, Ana Caroline; Rodrigues, Clenilson Martins; Sannomiya, Miriam; dos Santos Ramos, Matheus Aparecido; Bonifacio, Bruna Vidal; Bauab, This Maria; Tamashiro, Jorge; Machado da Rocha, Lucia Regina; Vilegas, Wagner; Hiruma-Lima, Clelia Akiko

Sex-specific effects of Eugenia punicifolla extract on gastric ulcer healing in rats

WORLD JOURNAL OF GASTROENTEROLOGY

IF5.4

2018-10-14

OAAI

Perico, Larissa Lucena; Rodrigues, Vinicius Peixoto; Ohara, Rie; Bueno, Gabriela; Alfieri Nunes, Vania Vasti; dos Santos, Raquel de Cassia; Lima Camargo, Ana Carolina; Justulin Junior, Luis Antonio; de Andrade, Sergio Faloni; Bispo Steimbach, Viviane Miranda; da Silva, Luisa Mota; Machado da Rocha, Lucia Regina; Vilegas, Wagner; dos Santos, Catarina; Hiruma-Lima, Clelia Akiko

New steroidal saponins and antiulcer activity from Solanum paniculatum L. (vol 186, pg 160, 2015)

FOOD CHEMISTRY

IF9.8

2017-01-01

PREAI

Vieira Junior, Gerardo M.; da Rocha, Claudia Quintino; Rodrigues, Tamires de Souza; Hiruma-Lima, Clelia Akiko; Vilegas, Wagner

New steroidal saponins and antiulcer activity from Solanum paniculatum L.

FOOD CHEMISTRY

IF9.8

2015-11-01

PREAI

Vieira Junior, Gerardo Magela; da Rocha, Claudia Quintino; Rodrigues, Tamires de Souza; Hiruma-Lima, Clelia Akiko; Vilegas, Wagner

Citral: A monoterpene with prophylactic and therapeutic anti-nociceptive effects in experimental models of acute and chronic pain

EUROPEAN JOURNAL OF PHARMACOLOGY

IF4.7

2014-08-01

PREAI

Nishijima, Catarine M.; Ganev, Ellen G.; Mazzardo-Martins, Leidiane; Martins, Daniel E.; Rocha, Lucia R. M.; Santos, Adair R. S.; Hiruma-Lima, Clelia A.

研究方向