未登录Disrupted glucocorticoid rhythms selectively induce severe skeletal muscle insulin resistance and uncouple obesity from hepatic steatosis糖皮质激素节律紊乱可选择性诱导严重骨骼肌胰岛素抵抗,并使肥胖与脂肪肝解偶联
Agas, Agnieszka; Sharma, Sanjeev; Narciso, Anthony; Saavedra, Lucas Paulo Jacinto; Wilson, Jijo; Lungstrum, Jack; Yammine, Lucie; Arzeno, Anna S.; Lantier, Louise; Kilkenny, Erin; Uddin, Ahsan; Echeverria, Carolina E.; Ferrick, Katherine R.; Nathoo, Isaac; Gao, Jonathan; Kapelczak, Edmund D.; Jacobo, Rashel; Patel, Roma; TeSlaa, Tara; Goncalves, Marcus D.; McGraw, Timothy E.; Teruel, Mary N.
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收藏Rab10 inactivation promotes AMPAR trafficking and spine enlargement during long-term potentiationRab10失活促进AMPA受体运输和树突棘增大,发生于长期增强过程中
Wang, Jie; Nishiyama, Jun; Parra-Bueno, Paula; Okaz, Elwy; Oz, Goksu; Liu, Xiaodan; Watabe, Tetsuya; Suponitsky-Kroyter, Irena; McGraw, Timothy E.; Szatmari, Erzsebet M.; Yasuda, Ryohei
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收藏Multiple beta cell-independent mechanisms drive hypoglycemia in Timothy syndrome
Matsui, Maiko; Lynch, Lauren E.; Distefano, Isabella; Galante, Allison; Gade, Aravind R.; Wang, Hong-Gang; Gomez-Banoy, Nicolas; Towers, Patrick; Sinden, Daniel S.; Wei, Eric Q.; Barnett, Adam S.; Johnson, Kenneth; Lima, Renan; Rubio-Navarro, Alfonso; Li, Ang K.; Marx, Steven O.; McGraw, Timothy E.; Thornton, Paul S.; Timothy, Katherine W.; Lo, James C.; Pitt, Geoffrey S.
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收藏Deficiency of metabolic regulator PKM2 activates the pentose phosphate pathway and generates TCF1+ progenitor CD8+ T cells to improve immunotherapy
Markowitz, Geoffrey J.; Ban, Yi; Tavarez, Diamile A.; Yoffe, Liron; Podaza, Enrique; He, Yongfeng; Martin, Mitchell T.; Crowley, Michael J. P.; Sandoval, Tito A.; Gao, Dingcheng; Martin, M. Laura; Elemento, Olivier; Cubillos-Ruiz, Juan R.; Mcgraw, Timothy E.; Altorki, Nasser K.; Mittal, Vivek
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收藏A signature of enhanced proliferation associated with response and survival to anti-PD-L1 therapy in early-stage non-small cell lung cancer
Altorki, Nasser K.; Bhinder, Bhavneet; Borczuk, Alain C.; Elemento, Olivier; Mittal, Vivek; Mcgraw, Timothy E.; Mcgraw, Timothy E.; Altorki, Nasser K.; Bhinder, Bhavneet; Borczuk, Alain C.; Elemento, Olivier; Mittal, Vivek
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收藏Neoadjuvant durvalumab plus radiation versus durvalumab alone in stages I-III non-small cell lung cancer: survival outcomes and molecular correlates of a randomized phase II trial (vol 19, 8435, 2023)
Altorki, Nasser K.; Walsh, Zachary H.; Melms, Johannes C.; Port, Jeffery L.; Lee, Benjamin E.; Nasar, Abu; Spinelli, Cathy; Caprio, Lindsay; Rogava, Meri; Ho, Patricia; Christos, Paul J.; Saxena, Ashish; Elemento, Olivier; Bhinder, Bhavneet; Ager, Casey; Amin, Amit Dipak; Sanfilippo, Nicholas J.; Mittal, Vivek; Borczuk, Alain C.; Formenti, Silvia C.; Izar, Benjamin; McGraw, Timothy E.
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收藏Regulated dynamic subcellular GLUT4 localization revealed by proximal proteome mapping in human muscle cells
Ray, Anuttoma; Wen, Jennifer; Yammine, Lucie; Culver, Jeff; Parida, Isabella Supardi; Garren, Jeonifer; Xue, Liang; Hales, Katherine; Xiang, Qing; Birnbaum, Morris J.; Zhang, Bei B.; Monetti, Mara; Mcgraw, Timothy E.
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收藏Neoadjuvant durvalumab plus radiation versus durvalumab alone in stages I-III non-small cell lung cancer: survival outcomes and molecular correlates of a randomized phase II trial
Altorki, Nasser K.; Walsh, Zachary H.; Melms, Johannes C.; Port, Jeffery L.; Lee, Benjamin E.; Nasar, Abu; Spinelli, Cathy; Caprio, Lindsay; Rogava, Meri; Ho, Patricia; Christos, Paul J.; Saxena, Ashish; Elemento, Olivier; Bhinder, Bhavneet; Ager, Casey; Amin, Amit Dipak; Sanfilippo, Nicholas J.; Mittal, Vivek; Borczuk, Alain C.; Formenti, Sylvia C.; Izar, Benjamin; Mcgraw, Timothy E.
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收藏Spatiotemporal regulation of GIPR signaling impacts glucose homeostasis as revealed in studies of a common GIPR variantGIPR信号的时空调控会影响葡萄糖稳态,如对常见GIPR变体的研究中所揭示的那样
Yammine, Lucie; Picatoste, Belen; Abdullah, Nazish; Leahey, Rosemary A.; Johnson, Emma F.; Gomez-Banoy, Nicolas; Rosselot, Carolina; Wen, Jennifer; Hossain, Tahmina; Goncalves, Marcus D.; Lo, James C.; Garcia-Ocana, Adolfo; McGraw, Timothy E.
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收藏TIMP1 is an early biomarker for detection and prognosis of lung cancer
Dantas, Ezequiel; Murthy, Anirudh; Ahmed, Tanvir; Ahmed, Mujmmail; Ramsamooj, Shakti; Hurd, Maurice A.; Lam, Tiffany; Malbari, Murtaza; Agrusa, Christopher; Elemento, Olivier; Zhang, Chen; Pappin, Darryl J.; McGraw, Timothy E.; Stiles, Brendon M.; Altorki, Nasser K.; Goncalves, Marcus D.
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收藏Deficiency of metabolic regulator PKM2 activates the pentose phosphate pathway to generate TCF1+progenitor CD8+T cells to improve checkpoint blockade
Markowitz, Geoffrey J.; Ban, Yi; Tavarez, Diamile A.; Crowley, Michael J.; Yoffe, Liron; Martin, Mitchell T.; Sandoval, Tito A.; Gao, Dingcheng; Cubillos-Ruiz, Juan R.; McGraw, Timothy E.; Altorki, Nasser K.; Mittal, Vivek
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收藏Tumor-intrinsic IRE1α signaling controls protective immunity in lung cancer
Crowley, Michael J. P.; Bhinder, Bhavneet; Markowitz, Geoffrey J.; Martin, Mitchell; Verma, Akanksha; Sandoval, Tito A.; Chae, Chang-Suk; Yomtoubian, Shira; Hu, Yang; Chopra, Sahil; Tavarez, Diamile A.; Giovanelli, Paolo; Gao, Dingcheng; McGraw, Timothy E.; Altorki, Nasser K.; Elemento, Olivier; Cubillos-Ruiz, Juan R.; Mittal, Vivek
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收藏Expression of the mono-ADP-ribosyltransferase ART1 by tumor cells mediates immune resistance in non-small cell lung cancer
Wennerberg, Erik; Mukherjee, Sumit; Spada, Sheila; Hung, Clarey; Agrusa, Christopher J.; Chen, Chuang; Valeta-Magara, Amanda; Rudqvist, Nils-Petter; Van Nest, Samantha J.; Kamel, Mohamed K.; Nasar, Abu; Narula, Navneet; Mittal, Vivek; Markowitz, Geoffrey J.; Zhou, Xi Kathy; Adusumilli, Prasad S.; Borczuk, Alain C.; White, Thomas E.; Khan, Abdul G.; Balderes, Paul J.; Lorenz, Ivo C.; Altorki, Nasser; Demaria, Sandra; McGraw, Timothy E.; Stiles, Brendon M.
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