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Advancing Personalized Medicine in Alzheimer's Disease: Liquid Biopsy Epigenomics Unveil APOE ε4-Linked Methylation Signatures 推进阿尔茨海默病个性化医学：液体活检表观基因组学揭示APOE ε4相关甲基化特征 Macias, Monica; Alba-Linares, Juan Jose; Acha, Blanca; Blanco-Luquin, Idoia; Fernandez, Agustin F.; Alvarez-Jimenez, Johana; Urdanoz-Casado, Amaya; Roldan, Miren; Robles, Maitane; Cabezon-Arteta, Eneko; Alcolea, Daniel; de Gordoa, Javier Sanchez Ruiz; Corroza, Jon; Cabello, Carolina; Erro, Maria Elena; Jerico, Ivonne; Fraga, Mario F.; Mendioroz, Maite 分享 收藏
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A multiomic atlas of the aging hippocampus reveals molecular changes in response to environmental enrichment 衰老海马的多体图谱揭示了响应环境富集的分子变化 Perez, Raul F.; Tezanos, Patricia; Penarroya, Alfonso; Gonzalez-Ramon, Alejandro; Urdinguio, Rocio G.; Gancedo-Verdejo, Javier; Tejedor, Juan Ramon; Santamarina-Ojeda, Pablo; Alba-Linares, Juan Jose; Sainz-Ledo, Lidia; Roberti, Annalisa; Lopez, Virginia; Mangas, Cristina; Moro, Maria; Reyes, Elisa Cintado; Martinez, Pablo Muela; Rodriguez-Santamaria, Mar; Ortea, Ignacio; Iglesias-Rey, Ramon; Castilla-Silgado, Juan; Tomas-Zapico, Cristina; Iglesias-Gutierrez, Eduardo; Fernandez-Garcia, Benjamin; Sanchez-Mut, Jose Vicente; Trejo, Jose Luis; Fernandez, Agustin F.; Fraga, Mario F. 分享 收藏
Novel 14q32.2 paternal deletion encompassing the whole DLK1 gene associated with Temple syndrome Baena, Neus; Monk, David; Aguilera, Cinthia; Fraga, Mario F.; Fernandez, Agustin F.; Gabau, Elisabeth; Corripio, Raquel; Capdevila, Nuria; Trujillo, Juan Pablo; Ruiz, Anna; Guitart, Miriam 分享 收藏
A personalized medicine approach identifies enasidenib as an efficient treatment for IDH2 mutant chondrosarcoma Rey, Veronica; Tornin, Juan; Alba-Linares, Juan Jose; Robledo, Cristina; Murillo, Dzohara; Rodriguez, Aida; Gallego, Borja; Huergo, Carmen; Viera, Cristina; Brana, Alejandro; Astudillo, Aurora; Heymann, Dominique; Szuhai, Karoly; Bovee, Judith V. M. G.; Fernandez, Agustin F.; Fraga, Mario F.; Alonso, Javier; Rodriguez, Rene 分享 收藏
A FokI-driven signal amplification platform for the simultaneous detection of multiple viral RNA pathogens Tejedor, Juan R.; Roberti, Annalisa; Mangas, Cristina; Alvarez-Arguelles, Marta E.; Rojo-Alba, Susana; Boga, Jose A.; Fernandez, Agustin F.; Melon, Santiago; Rodriguez, Mercedes; Fraga, Mario F. 分享 收藏
CRISPR/dCAS9-mediated DNA demethylation screen identifies functional epigenetic determinants of colorectal cancer CRISPR/dCAS9-mediated DNA去甲基化筛选鉴定结直肠癌的功能性表观遗传决定因素 Tejedor, Juan Ramon; Penarroya, Alfonso; Gancedo-Verdejo, Javier; Santamarina-Ojeda, Pablo; Perez, Raul F.; Lopez-Tamargo, Sara; Diez-Borge, Ana; Alba-Linares, Juan J.; Gonzalez-del-Rey, Nerea; Urdinguio, Rocio G.; Mangas, Cristina; Roberti, Annalisa; Lopez, Virginia; Morales-Ruiz, Teresa; Ariza, Rafael R.; Roldan-Arjona, Teresa; Meijon, Monica; Valledor, Luis; Canal, Maria Jesus; Fernandez-Martinez, Daniel; Fernandez-Hevia, Maria; Jimenez-Fonseca, Paula; Garcia-Florez, Luis J.; Fernandez, Agustin F.; Fraga, Mario F. 分享 收藏
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Nicotinamide N-methyltransferase (NNMT) regulates the glucocorticoid signaling pathway during the early phase of adipogenesis Roberti, Annalisa; Tejedor, Juan Ramon; Diaz-Moreno, Irene; Lopez, Virginia; Santamarina-Ojeda, Pablo; Perez, Raul F.; Urdinguio, Rocio G.; Concellon, Carmen; Martinez-Chantar, Maria Luz; Fernandez-Morera, Juan Luis; Diaz-Quintana, Antonio; del Amo, Vicente; Fernandez, Agustin F.; Fraga, Mario F. 分享 收藏
The TINCR ubiquitin-like microprotein is a tumor suppressor in squamous cell carcinoma Morgado-Palacin, Lucia; Brown, Jessie A.; Martinez, Thomas F.; Garcia-Pedrero, Juana M.; Forouhar, Farhad; Quinn, S. Aidan; Reglero, Clara; Vaughan, Joan; Heydary, Yasamin Hajy; Donaldson, Cynthia; Rodriguez-Perales, Sandra; Allonca, Eva; Granda-Diaz, Rocio; Fernandez, Agustin F.; Fraga, Mario F.; Kim, Arianna L.; Santos-Juanes, Jorge; Owens, David M.; Rodrigo, Juan P.; Saghatelian, Alan; Ferrando, Adolfo A. 分享 收藏
Maternal obesity and gestational diabetes reprogram the methylome of offspring beyond birth by inducing epigenetic signatures in metabolic and developmental pathways Alba-Linares, Juan Jose; Perez, Raul F.; Tejedor, Juan Ramon; Bastante-Rodriguez, David; Ponce, Francisco; Carbonell, Nuria Garcia; Zafra, Rafael Gomez; Fernandez, Agustin F.; Fraga, Mario F.; Lurbe, Empar 分享 收藏
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Classification of follicular-patterned thyroid lesions using a minimal set of epigenetic biomarkers Rodriguez-Rodero, Sandra; Morales-Sanchez, Paula; Tejedor, Juan Ramon; Coca-Pelaz, Andres; Mangas, Cristina; Penarroya, Alfonso; Fernandez-Vega, Ivan; Fernandez-Fernandez, Luis; Alvarez-Lopez, Carmen M.; Fernandez, Agustin F.; Alvarez, Marina Arranz; Astudillo, Aurora; Alarcon, Pedro Pujante; Ragnarsson, Cecilia; Alonso, Alberto Colina; Rivas, Hector Enrique Torres; Rodrigo Tapia, Juan Pablo; Torrero, Sandra Nieto; Pedroche-Just, Yaiza; Zapata, Rita Maria Regojo; Rodriguez-Garcia, Ana M.; Abo, Anabel; Balbin, Milagros; Menendez, Edelmiro; Delgado, Elias; Fraga, Mario F. 分享 收藏
Enhanced Detection of Viral RNA Species Using Fokl-Assisted Digestion of DNA Duplexes and DNA/RNA Hybrids Tejedor, Juan R.; Martin, Gabriel; Roberti, Annalisa; Mangas, Cristina; Santamarina-Ojeda, Pablo; Fernandez Perez, Raul; Lopez, Virginia; Gonzalez Urdinguio, Rocio; Alba-Linares, Juan J.; Penarroya, Alfonso; Alvarez-Arguelles, Marta E.; Boga, Jose A.; Fernandez Fernandez, Agustin; Rojo-Alba, Susana; Fernandez Fraga, Mario 分享 收藏
Blood DNA Methylation Patterns in Older Adults With Evolving Dementia Fernandez Perez, Raul; Jose Alba-Linares, Juan; Ramon Tejedor, Juan; Fernandez Fernandez, Agustin; Calero, Miguel; Roman-Dominguez, Aurora; Borras, Consuelo; Vina, Jose; Avila, Jesus; Medina, Miguel; Fernandez Fraga, Mario 分享 收藏
Physical exercise shapes the mouse brain epigenome Urdinguio, Rocio G.; Tejedor, Juan Ramon; Fernandez-Sanjurjo, Manuel; Perez, Raul F.; Penarroya, Alfonso; Ferrero, Cecilia; Codina-Martinez, Helena; Diez-Planelles, Carlos; Pinto-Hernandez, Paola; Castilla-Silgado, Juan; Coto-Vilcapoma, Almudena; Diez-Robles, Sergio; Blanco-Agudin, Noelia; Tomas-Zapico, Cristina; Iglesias-Gutierrez, Eduardo; Fernandez-Garcia, Benjamin; Fernandez, Agustin F.; Fraga, Mario F. 分享 收藏
Conservation of Aging and Cancer Epigenetic Signatures across Human and Mouse (vol 38, pg 3415, 2021) Perez, Raul F.; Tejedor, Juan Ramon; Santamarina-Ojeda, Pablo; Martinez, Virginia Lopez; Urdinguio, Rocio G.; Villamanan, Lucia; Candiota, Ana Paula; Sarro, Noemi Vidal; Barradas, Marta; Fernandez-Marcos, Pablo Jose; Serrano, Manuel; Fernandez, Agustin F.; Fraga, Mario F. 分享 收藏
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