Seung-Hwan Lee - Publications, H-index & Citations

Seung-Hwan Lee

University of Ottawa

4H指数

14论文数

142被引数

收录论文 9

发表时间

AMPKα regulates glycolytic reprogramming to sustain NK cell proliferation and effector function AMPKα调节糖酵解重编程以维持NK细胞增殖和效应功能

Cell Death & Disease

IF9.6

2026-09-11

OAAI

Abrar Ul Haq Khan; Jannat Pervin; Safa Ghaziasgar; Claire Fong-McMaster; Haytham Msallak; Min Du; Marc Foretz; Benoit Viollet; Lisheng Wang; Mary-Ellen Harper; Morgan D. Fullerton; Seung-Hwan Lee

Development of Genetically Modified ARH-77 Feeder Cells for Efficient Expansion of Natural Killer Cells with Potent Anti-Tumor Activity 利用基因改造的ARH-77饲养细胞高效扩增具有强抗肿瘤活性的自然杀伤细胞

Cancers

IF4.4

2026-06-03

OAAI

Yu-Jin Lim; Bryan Marr; Safa Ghaziasgar; Cheol-Jung Kim; Yeon-Ju Baek; Geun-Seop Kim; Je-Jung Lee; Yu-Jin Park; Yurim An; Seung-Hwan Lee; Sang-Ki Kim

BaEV-pseudotyped lentiviral vectors enable stable CAR expression and cytotoxic function in NK cells BaEV假型化慢病毒载体使NK细胞中CAR稳定表达并发挥细胞毒性功能

PLoS One

IF2.6

2026-05-01

PREAI

Park, Minji; Lim, Yuree; Jo, Yujung; Jo, Dong-Hyeon; Kim, Sang-Ki; Kim, Hyun-Young; Lee, Seung-Hwan; Lee, Mijeong; Cho, Duck

Natural Killer Cell-Derived Extracellular Vesicles Exhibit Cytotoxicity Against Bulk Tumor Cells and Cancer Stem Cells in Triple-Negative Breast Cancer 自然杀伤细胞来源的细胞外囊泡对三阴性乳腺癌中的肿瘤细胞群和癌症干细胞表现出细胞毒性

Nanomaterials

IF4.3

2026-04-27

OAAI

Melanie Kirkby; Frederic St-Denis-Bissonnette; Marena D. Diab; Karan Mediratta; Anna Korobkow; James Humber; Peter Han; Gauri Muradia; Michele Ardolino; Seung-Hwan Lee; Derrick J. Gibbings; Dylan Burger; Lisheng Wang; Jessie R. Lavoie

Rapid CAR screening and circRNA-driven CAR-NK cells for persistent shed-resistant immunotherapy 快速CAR筛查及环状RNA驱动的CAR-NK细胞用于持久性脱落抗性免疫治疗

Signal Transduction and Targeted Therapy

IF52.7

2026-04-10

OAAI

Joo-Yoon Chung; Jisu Hong; Su-Min Yee; Hye Won Lim; Dahye Lee; Sangwon Yoon; Seung-Hwan Lee; Yujin Jung; Seung Hun Shin; Song Cheol Kim; Chang-Han Lee; Mihue Jang

Anti-BCMA-CAR-IL15 natural killer cells prevent multiple myeloma growth in the bone marrow but allow subsequent emergence of extramedullary disease 抗BCMA-CAR-IL15自然杀伤细胞可抑制骨髓中的多发性骨髓瘤生长，但允许随后出现髓外病变。

Cancer Letters

IF10.1

2025-12-24

OAAI

Shelby Kaczmarek; Donghyeon Jo; Safa Ghaziasgar; Bryan Marr; Stefania Berton; Lisheng Wang; Mehdi Arbabi Ghahroudi; Mihue Jang; Alissa Visram; Scott McComb; Seung-Hwan Lee

The impact of low-dose gamma radiation on immune modulation in a mouse model of spontaneous mammary gland tumorigenesis 低剂量伽马辐射对自发性乳腺肿瘤发生小鼠模型中免疫调节的影响

Frontiers in Immunology

IF5.9

2025-11-03

OAAI

Abrar Ul Haq Khan; Melinda Blimkie; Bryan Marr; Jin Wu; Tyler Pack; Shelby Kaczmarek; Dong-Hyeon Jo; Holly Laakso; Seung-Hwan Lee

Can Engineering IL-2Rα Expression Improve NK Cell Immunotherapy?

JOURNAL OF IMMUNOLOGY

IF3.4

2023-05-01

OAAI

Lee, Seung-Hwan; Marr, Bryan; Jo, Donghyeon; McComb, Scott