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收藏PYX-201, a stroma-targeting ADC composed of an anti-EDB plus FN antibody conjugated to Auristatin0101, demonstrates strong anti-tumor efficacy across multiple human cancer indications in pre-clinical PDX tumor models
Severe, Nicolas; Facklam, Amanda; McMichael, Liz; Das, Biplab; Lewandowski, Sara; Trickett, Justin; Diao, Liyang; Merriman, Chengfeng; Shen, Chuan; Feng, Jianwen; Harriman, Shawn; Crochiere, Marsha; Steiner, Philipp; Pinkas, Jan
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收藏Quantitation of total antibody (tAb) from antibody drug conjugate (ADC) PYX-201 in rat and monkey plasma using an enzyme-linked immunosorbent assay (ELISA) and its application in preclinical studies
Yin, Feng; DeCiantis, Chris; Pinkas, Jan; Das, Biplab; Wang, Frank; Zheng, Nancy; Hahn, David; Amrite, Aniruddha; Feng, Jianwen; Adhikari, Diana; Kane, Cheikh; Sikora, Jack; Pittman, Justin; Wates, Rebecca; Shaheen, Elizabeth; Harriman, Shawn
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