未登录 Mitochondrial Ca2+uniporter haploinsufficiency leads to sexually dimorphic redox imbalance and metabolic remodelling in the mouse brain 线粒体Ca2+uniporter单倍剂量不足会导致小鼠脑部出现性二态性的氧化还原失衡和代谢重塑。 Gray, Jenna; Halemirle, Girish; Ferran, Beatriz; Rose, Hadyn; Redwine, Traci L.; Pham, Sophia; Hagy, Bo; Pranay, Atul; Giorgione, Jennifer; Hussong, Stacy A.; Galvan, Veronica; Humphries, Kenneth; Van Remmen, Holly; Kinter, Mike; Sonntag, William E.; Singh, Pankaj K.; Diaz-Garcia, Carlos Manlio 分享 收藏
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Impaired Neurovascular Coupling and Increased Functional Connectivity in the Frontal Cortex Predict Age-Related Cognitive Dysfunction Mukli, Peter; Pinto, Camila B.; Owens, Cameron D.; Csipo, Tamas; Lipecz, Agnes; Szarvas, Zsofia; Peterfi, Anna; Langley, Ana Clara da Costa Pinaffi; Hoffmeister, Jordan; Racz, Frigyes Samuel; Perry, Jonathan W.; Tarantini, Stefano; Nyul-Toth, Adam; Sorond, Farzaneh A.; Yang, Yuan; James, Judith A.; Kirkpatrick, Angelia C.; Prodan, Calin I.; Toth, Peter; Galindo, Juliette; Gardner, Andrew W.; Sonntag, William E.; Csiszar, Anna; Ungvari, Zoltan; Yabluchanskiy, Andriy 分享 收藏
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Elimination of senescent cells by treatment with Navitoclax/ABT263 reverses whole brain irradiation-induced blood-brain barrier disruption in the mouse brain Gulej, Rafal; Nyul-Toth, Adam; Ahire, Chetan; Delfavero, Jordan; Balasubramanian, Priya; Kiss, Tamas; Tarantini, Stefano; Benyo, Zoltan; Pacher, Pal; Csik, Boglarka; Yabluchanskiy, Andriy; Mukli, Peter; Kuan-Celarier, Anna; Krizbai, Istvan A.; Campisi, Judith; Sonntag, William E.; Csiszar, Anna; Ungvari, Zoltan 分享 收藏
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Cognitive heterogeneity reveals molecular signatures of age-related impairment Logan, Sreemathi; Baier, Matthew P.; Owen, Daniel B.; Peasari, John; Jones, Kenneth L.; Ranjit, Rojina; Yarbrough, Hannah P.; Masingale, Anthony M.; Bhandari, Suyesha; Rice, Heather C.; Kinter, Michael T.; Sonntag, William E. 分享 收藏
Measurements of cerebral microvascular blood flow, oxygenation, and morphology in a mouse model of whole-brain irradiation-induced cognitive impairment by two-photon microscopy and optical coherence tomography: evidence for microvascular injury in the cerebral white matter 通过双光子显微镜和光学相干断层扫描测量全脑照射诱发的认知障碍小鼠模型中的脑微血管血流，氧合作用和形态: 脑白质中微血管损伤的证据 Li, Baoqiang; Yabluchanskiy, Andriy; Tarantini, Stefano; Allu, Srinivasa Rao; Sencan-Egilmez, Ikbal; Leng, Ji; Alfadhel, Mohammed Ali H.; Porter, Jason E.; Fu, Buyin; Ran, Chongzhao; Erdener, Sefik Evren; Boas, David A.; Vinogradov, Sergei A.; Sonntag, William E.; Csiszar, Anna; Ungvari, Zoltan; Sakadzic, Sava 分享 收藏
Decreased lifespan in female Munchkin actors from the cast of the 1939 film version of The Wizard of Oz does not support the hypothesis linking hypopituitary dwarfism to longevity Fazekas-Pongor, Vince; Peterfi, Anna; Major, David; Szarvas, Zsofia; Fekete, Monika; Tabak, Adam G.; Csiszar, Anna; Sonntag, William E.; Austad, Steven N.; Ungvari, Zoltan, I 分享 收藏
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Increased Susceptibility to Cerebral Microhemorrhages Is Associated With Imaging Signs of Microvascular Degeneration in the Retina in an Insulin-Like Growth Factor 1 Deficient Mouse Model of Accelerated Aging 在胰岛素样生长因子1缺乏的加速衰老小鼠模型中，对脑微出血的易感性增加与视网膜微血管变性的影像学征象有关 Miller, Lauren R. R.; Tarantini, Stefano; Nyul-Toth, Adam; Johnston, Morgan P. P.; Martin, Teryn; Bullen, Elizabeth C. C.; Bickel, Marisa A. A.; Sonntag, William E. E.; Yabluchanskiy, Andriy; Csiszar, Anna; Ungvari, Zoltan I. I.; Elliott, Michael H. H.; Conley, Shannon M. M. 分享 收藏
Sleep deprivation impairs cognitive performance, alters task-associated cerebral blood flow and decreases cortical neurovascular coupling-related hemodynamic responses 睡眠剥夺会损害认知能力，改变与任务相关的脑血流量，并降低与皮质神经血管耦合相关的血液动力学反应 Csipo, Tamas; Lipecz, Agnes; Owens, Cameron; Mukli, Peter; Perry, Jonathan W.; Tarantini, Stefano; Balasubramanian, Priya; Nyul-Toth, Adam; Yabluchanska, Valeriya; Sorond, Farzaneh A.; Kellawan, J. Mikhail; Purebl, Gyorgy; Sonntag, William E.; Csiszar, Anna; Ungvari, Zoltan; Yabluchanskiy, Andriy 分享 收藏
Oklahoma Nathan Shock Aging Center - assessing the basic biology of aging from genetics to protein and function Van Remmen, Holly; Freeman, Willard M.; Miller, Benjamin F.; Kinter, Michael; Wren, Jonathan D.; Chiao, Ann; Towner, Rheal A.; Snider, Timothy A.; Sonntag, William E.; Richardson, Arlan 分享 收藏
Endothelial deficiency of insulin-like growth factor-1 receptor (IGF1R) impairs neurovascular coupling responses in mice, mimicking aspects of the brain aging phenotype 胰岛素样生长因子-1受体 (IGF1R) 的内皮缺陷会损害小鼠的神经血管偶联反应，模仿大脑衰老表型的各个方面 Tarantini, Stefano; Nyul-Toth, Adam; Yabluchanskiy, Andriy; Csipo, Tamas; Mukli, Peter; Balasubramanian, Priya; Ungvari, Anna; Toth, Peter; Benyo, Zoltan; Sonntag, William E.; Ungvari, Zoltan; Csiszar, Anna 分享 收藏
Sleep deprivation alters task-related changes in functional connectivity of the frontal cortex: A near-infrared spectroscopy study Mukli, Peter; Csipo, Tamas; Lipecz, Agnes; Stylianou, Orestis; Racz, Frigyes Samuel; Owens, Cameron D.; Perry, Jonathan W.; Tarantini, Stefano; Sorond, Farzaneh A.; Kellawan, Jeremy M.; Purebl, Gyorgy; Yang, Yuan; Sonntag, William E.; Csiszar, Anna; Ungvari, Zoltan, I; Yabluchanskiy, Andriy 分享 收藏
IGF1R signaling regulates astrocyte-mediated neurovascular coupling in mice: implications for brain aging Tarantini, Stefano; Balasubramanian, Priya; Yabluchanskiy, Andriy; Ashpole, Nicole M.; Logan, Sreemathi; Kiss, Tamas; Ungvari, Anna; Nyul-Toth, Adam; Schwartzman, Michal L.; Benyo, Zoltan; Sonntag, William E.; Csiszar, Anna; Ungvari, Zoltan 分享 收藏
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Pharmacological or genetic depletion of senescent astrocytes prevents whole brain irradiation-induced impairment of neurovascular coupling responses protecting cognitive function in mice Yabluchanskiy, Andriy; Tarantini, Stefano; Fulop, Gabor; Kiss, Tamas; Balasubramanian, Priya; DelFavero, Jordan; Ahire, Chetan; Csipo, Tamas; Nyul-Toth, Adam; Lipecz, Agnes; Sonntag, William; Schwartzman, Michal; Campisi, Judith; Csiszar, Anna; Ungvari, Zoltan 分享 收藏
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