logo
科言猫学术研究的AI总结
language
手机端手机端
  • Phone Feature微信小程序
简体中文简体中文
notice消息通知
博客博客
delete
arrow
返回
T

Toshiyuki Shimizu

university of tokyo

61H指数
346论文数
1.3W被引数
收录论文 124
发表时间
logo
The pyrin domain of IFI16 forms a distinct filament structure important for IFI16-mediated enhancement of STING activationIFI16的PYRIN结构域形成一种独特的丝状结构，该结构对IFI16介导的STING激活增强至关重要。
errStructure
IF4.3
err2026-02-19
err0
PREAI
errRyuichi Takahashi; Zhikuan Zhang; Akiko Fujimura; Umeharu Ohto; Toshiyuki Shimizu
err分享
err收藏
2′-O-Methyl-guanosine RNA fragments antagonize TLR7 and TLR8 to limit autoimmunity2 ′-O-甲基-鸟苷RNA片段拮抗TLR7和TLR8以限制自身免疫
errNature Immunology
IF27.6
err2026-02-10
err0
errOAAI
errArwaf S. Alharbi; Sunil Sapkota; Zhikuan Zhang; Ruitao Jin; Erandi Rupasinghe; W. Samantha N. Jayasekara; Dingyi Yu; Mary Speir; Lorna Wilkinson-White; Liza Cubeddu; Julia I. Ellyard; Refaya Rezwan; Daniel S. Wenholz; Alexandra L. McAllan; Rui Gao; Le Ying; Rasan M. Sathiqu; Hani Hosseini Far; Josiah Bones; Sitong He; Marina R. Alexander; Kim A. Lennox; Paul J. Hertzog; Claudia A. Nold-Petry; Cameron R. Stewart; Carola G. Vinuesa; Mark A. Behlke; Umeharu Ohto; Olivier F. Laczka; Roland Gamsjaeger; Ben Corry; Toshiyuki Shimizu; Michael P. Gantier
err分享
err收藏
Mechanistic insights into single-stranded DNA degradation by lysosomal exonucleases PLD3 and PLD4 from structural snapshots通过溶酶体外切核酸酶PLD3和PLD4的结构快照揭示单链DNA降解的机制性见解
errNature Communications
IF15.7
err2025-12-11
err0
errOAAI
errYoshinori Hirano; Wakiko Ezaki; Ryota Sato; Umeharu Ohto; Kensuke Miyake; Toshiyuki Shimizu
err分享
err收藏
Effects of Tetracycline on Growth and Nutrient Removal by Lemna aoukikusa and Spirodela polyrhiza Under Short-Term Cultivation
errAPPLIED SCIENCES-BASEL
IF2.5
err2025-10-30
err0
errOAAI
errDinh, Uyen Thi To; Nakagawa, Shoki; Shimizu, Toshiyuki; Soda, Satoshi
err分享
err收藏
Structural insights into Wnt/β-catenin signaling regulation by LGR4, R-spondin, and ZNRF3LGR4、R-spondin和ZNRF3对Wnt/β-catenin信号传导调控的结构洞察
errNature Communications
IF15.7
err2025-10-01
err0
errOAAI
errYuxuan Peng; Akiko Fujimura; Jinta Asami; Zhikuan Zhang; Toshiyuki Shimizu; Umeharu Ohto
err分享
err收藏
Anti-human TLR7 antibody for therapeutic intervention in systemic lupus erythematosus抗人TLR7抗体用于系统性红斑狼疮的疗法干预
errInternational Immunology
IF3.2
err2025-09-01
err2
errOAAI
errFukui, Ryutaro; Murakami, Yusuke; Kanno, Atsuo; Motoi, Yuji; Manno, Atsushi; Honda, Tomohiro; Yamada, Shinnosuke; Ishiguro, Jun; Kagari, Takashi; Nakamura, Kensuke; Kadokura, Michinori; Isobe, Takashi; Tomimori, Yoshiaki; Tanaka, Jun; Senaldi, Giorgio; Shimizu, Toshiyuki; Miyake, Kensuke
err分享
err收藏
Recent advances in structural studies of NLRP3 and NLRP1 inflammasome regulationNLRP3和NLRP1炎症小体调控的结构研究最新进展
errCURRENT OPINION IN STRUCTURAL BIOLOGY
IF7
err2025-06-01
err0
PREAI
errZhang, Zhikuan; Shimizu, Toshiyuki
err分享
err收藏
Targeting toll-like receptor 7 as a therapeutic development strategy for systemic lupus erythematosus
errACTA PHARMACEUTICA SINICA B
IF14.6
err2024-11-01
err0
errOAAI
errWang, Meng; Chen, Hekai; Zhang, Tuan; Zhang, Zhikuan; Xiang, Xuwen; Gao, Meng; Guo, Yilan; Jiang, Shuangshuang; Yin, Kejun; Chen, Mintao; Huang, Jian; Zhong, Xincheng; Ohto, Umeharu; Li, Jing; Shimizu, Toshiyuki; Yin, Hang
err分享
err收藏
Cryo-EM structures of the zinc transporters ZnT3 and ZnT4 provide insights into their transport mechanisms锌转运蛋白ZnT3和ZnT4的cryo-em结构提供了对其转运机制的见解
errFEBS LETTERS
IF3
err2024-10-30
err0
errOAAI
errIshida, Hanako; Yo, Riri; Zhang, Zhikuan; Shimizu, Toshiyuki; Ohto, Umeharu
err分享
err收藏
RNA recognition in toll-like receptor signaling
errCURRENT OPINION IN STRUCTURAL BIOLOGY
IF7
err2024-10-01
err0
errOAAI
errShimizu, Toshiyuki
err分享
err收藏
Cryo-EM analysis reveals human SID-1 transmembrane family member 1 dynamics underlying lipid hydrolytic activity
errCOMMUNICATIONS BIOLOGY
IF5.1
err2024-05-29
err3
errOAAI
errHirano, Yoshinori; Ohto, Umeharu; Ichi, Ikuyo; Sato, Ryota; Miyake, Kensuke; Shimizu, Toshiyuki
err分享
err收藏
Structural basis of hepatitis B virus receptor binding
errNATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
err2024-01-17
err10
PREAI
errAsami, Jinta; Park, Jae-Hyun; Nomura, Yayoi; Kobayashi, Chisa; Mifune, Junki; Ishimoto, Naito; Uemura, Tomoko; Liu, Kehong; Sato, Yumi; Zhang, Zhikuan; Muramatsu, Masamichi; Wakita, Takaji; Drew, David; Iwata, So; Shimizu, Toshiyuki; Watashi, Koichi; Park, Sam-Yong; Nomura, Norimichi; Ohto, Umeharu
err分享
err收藏
A novel Toll-like receptor 7/8-specific antagonist E6742 ameliorates clinically relevant disease parameters in murine models of lupus
errEUROPEAN JOURNAL OF PHARMACOLOGY
IF4.7
err2023-10-01
err7
errOAAI
errIshizaka, Sally T.; Hawkins, Lynn; Chen, Qian; Tago, Fumitoshi; Yagi, Takuya; Sakaniwa, Kentaro; Zhang, Zhikuan; Shimizu, Toshiyuki; Shirato, Manabu
err分享
err收藏
Discovery of a cystathionine γ-lyase (CSE) selective inhibitor targeting active-site pyridoxal 5′-phosphate (PLP) via Schiff base formation
errSCIENTIFIC REPORTS
IF3.9
err2023-09-30
err4
errOAAI
errEchizen, Honami; Hanaoka, Kenjiro; Shimamoto, Kazuhito; Hibi, Ryota; Toma-Fukai, Sachiko; Ohno, Hisashi; Sasaki, Eita; Komatsu, Toru; Ueno, Tasuku; Tsuchiya, Yukihiro; Watanabe, Yasuo; Otsuka, Takao; Saito, Hiroaki; Nagatoishi, Satoru; Tsumoto, Kouhei; Kojima, Hirotatsu; Okabe, Takayoshi; Shimizu, Toshiyuki; Urano, Yasuteru
err分享
err收藏
TLR7/8 stress response drives histiocytosis in SLC29A3 disordersTLR7/8应激反应驱动SLC29A3疾病中的组织细胞增生症
errJOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
err2023-07-18
err8
errOAAI
errShibata, Takuma; Sato, Ryota; Taoka, Masato; Saitoh, Shin-Ichiroh; Komine, Mayumi; Yamaguchi, Kiyoshi; Goyama, Susumu; Motoi, Yuji; Kitaura, Jiro; Izawa, Kumi; Yamauchi, Yoshio; Tsukamoto, Yumiko; Ichinohe, Takeshi; Fujita, Etsuko; Hiranuma, Ryosuke; Fukui, Ryutaro; Furukawa, Yoichi; Kitamura, Toshio; Takai, Toshiyuki; Tojo, Arinobu; Ohtsuki, Mamitaro; Ohto, Umeharu; Shimizu, Toshiyuki; Ozawa, Manabu; Yoshida, Nobuaki; Isobe, Toshiaki; Latz, Eicke; Mukai, Kojiro; Taguchi, Tomohiko; Hemmi, Hiroaki; Akira, Shizuo; Miyake, Kensuke
err分享
err收藏
TLR3 forms a laterally aligned multimeric complex along double-stranded RNA for efficient signal transductionTLR3沿着双链RNA形成横向排列的多聚体复合物，用于有效的信号转导
errNATURE COMMUNICATIONS
IF15.7
err2023-01-11
err14
errOAAI
errSakaniwa, Kentaro; Fujimura, Akiko; Shibata, Takuma; Shigematsu, Hideki; Ekimoto, Toru; Yamamoto, Masaki; Ikeguchi, Mitsunori; Miyake, Kensuke; Ohto, Umeharu; Shimizu, Toshiyuki
err分享
err收藏
Frontiers on innate immunity and intercellular communication
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2022-12-19
err1
errOAAI
errXiao, Yu; Zhang, Ying; Yin, Hang; Shimizu, Toshiyuki
err分享
err收藏
Structural insight into the activation of an Arabidopsis organellar C-to-U RNA editing enzyme by active site complementation
errPLANT CELL
IF11.6
err2022-11-07
err12
errOAAI
errToma-Fukai, Sachiko; Sawada, Yuto; Maeda, Ayako; Shimizu, Hikaru; Shikanai, Toshiharu; Takenaka, Mizuki; Shimizu, Toshiyuki
err分享
err收藏
Structure of SARS-CoV-2 membrane protein essential for virus assembly
errNATURE COMMUNICATIONS
IF15.7
err2022-08-05
err115
errOAAI
errZhang, Zhikuan; Nomura, Norimichi; Muramoto, Yukiko; Ekimoto, Toru; Uemura, Tomoko; Liu, Kehong; Yui, Moeko; Kono, Nozomu; Aoki, Junken; Ikeguchi, Mitsunori; Noda, Takeshi; Iwata, So; Ohto, Umeharu; Shimizu, Toshiyuki
err分享
err收藏
Discovery of a lectin domain that regulates enzyme activity in mouse N-acetylglucosaminyltransferase-IVa (MGAT4A)
errCOMMUNICATIONS BIOLOGY
IF5.1
err2022-07-19
err10
errOAAI
errNagae, Masamichi; Hirata, Tetsuya; Tateno, Hiroaki; Mishra, Sushil K.; Manabe, Noriyoshi; Osada, Naoko; Tokoro, Yuko; Yamaguchi, Yoshiki; Doerksen, Robert J.; Shimizu, Toshiyuki; Kizuka, Yasuhiko
err分享
err收藏

研究方向

暂时未获取到该数据
合作学者
合作期刊
S
Shizuo Akira
H 指数: 269 · 论文数: 1.5K
M
M. Aoki
H 指数: 137 · 论文数: 2.4K
K
Kozo Kaibuchi
H 指数: 135 · 论文数: 690
E
Eicke Latz
H 指数: 128 · 论文数: 508
A
Akira Isogai
H 指数: 102 · 论文数: 866
查看更多