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收藏Rational optimization of a transcription factor activation domain inhibitor转录因子激活域抑制剂的合理优化
Basu, Shaon; Martinez-Cristobal, Paula; Frigole-Vivas, Marta; Pesarrodona, Mireia; Lewis, Michael; Szulc, Elzbieta; Banuelos, C. Adriana; Sanchez-Zarzalejo, Carolina; Bielskute, Stase; Zhu, Jiaqi; Pombo-Garcia, Karina; Garcia-Cabau, Carla; Zodi, Levente; Dockx, Hannes; Smak, Jordann; Kaur, Harpreet; Batlle, Cristina; Mateos, Borja; Biesaga, Mateusz; Escobedo, Albert; Bardia, Lidia; Verdaguer, Xavier; Ruffoni, Alessandro; Mawji, Nasrin R.; Wang, Jun; Obst, Jon K.; Tam, Teresa; Brun-Heath, Isabelle; Ventura, Salvador; Meierhofer, David; Garcia, Jesus; Robustelli, Paul; Stracker, Travis H.; Sadar, Marianne D.; Riera, Antoni; Hnisz, Denes; Salvatella, Xavier 分享 收藏 Histone H3 serine-57 is a CHK1 substrate whose phosphorylation affects DNA repairParisis, Nikolaos; Dans, Pablo D.; Jbara, Muhammad; Singh, Balveer; Schausi-Tiffoche, Diane; Molina-Serrano, Diego; Brun-Heath, Isabelle; Hendrychova, Denisa; Maity, Suman Kumar; Buitrago, Diana; Lema, Rafael; Achour, Thiziri Nait; Giunta, Simona; Girardot, Michael; Talarek, Nicolas; Rofidal, Valerie; Danezi, Katerina; Coudreuse, Damien; Prioleau, Marie-Noelle; Feil, Robert; Orozco, Modesto; Brik, Ashraf; Wu, Pei-Yun Jenny; Krasinska, Liliana; Fisher, Daniel 分享 收藏 Characterization of p38α autophosphorylation inhibitors that target the non-canonical activation pathwayGonzalez, Lorena; Diaz, Lucia; Pous, Joan; Baginski, Blazej; Duran-Corbera, Anna; Scarpa, Margherita; Brun-Heath, Isabelle; Igea, Ana; Martin-Malpartida, Pau; Ruiz, Lidia; Pallara, Chiara; Esguerra, Mauricio; Colizzi, Francesco; Mayor-Ruiz, Cristina; Biondi, Ricardo M.; Soliva, Robert; Macias, Maria J.; Orozco, Modesto; Nebreda, Angel R. 分享 收藏 Controlled sulfur-based engineering confers mouldability to phosphorothioate antisense oligonucleotidesGenna, Vito; Iglesias-Fernandez, Javier; Reyes-Fraile, Laura; Villegas, Nuria; Guckian, Kevin; Seth, Punit; Wan, Brad; Cabrero, Cristina; Terrazas, Montserrat; Brun-Heath, Isabelle; Gonzalez, Carlos; Sciabola, Simone; Villalobos, Anabella; Orozco, Modesto 分享 收藏 MiOS, an integrated imaging and computational strategy to model gene folding with nucleosome resolutionVictoria Neguembor, Maria; Pablo Arcon, Juan; Buitrago, Diana; Lema, Rafael; Walther, Jurgen; Garate, Ximena; Martin, Laura; Romero, Pablo; Abed, Jumana AlHaj; Gut, Marta; Blanc, Julie; Lakadamyali, Melike; Wu, Chao-ting; Brun Heath, Isabelle; Orozco, Modesto; Dans, Pablo D.; Cosma, Maria Pia 分享 收藏 A method for multiplexed full-length single-molecule sequencing of the human mitochondrial genomeKeraite, Ieva; Becker, Philipp; Canevazzi, Davide; Frias-Lopez, Cristina; Dabad, Marc; Tonda-Hernandez, Raul; Paramonov, Ida; Ingham, Matthew John; Brun-Heath, Isabelle; Leno, Jordi; Abuli, Anna; Garcia-Arumi, Elena; Heath, Simon Charles; Gut, Marta; Gut, Ivo Glynne 分享 收藏 分享 收藏 Bioactivity descriptors for uncharacterized chemical compounds未表征化合物的生物活性描述符Bertoni, Martino; Duran-Frigola, Miquel; Badia-i-Mompel, Pau; Pauls, Eduardo; Orozco-Ruiz, Modesto; Guitart-Pla, Oriol; Alcalde, Victor; Diaz, Victor M.; Berenguer-Llergo, Antoni; Brun-Heath, Isabelle; Villegas, Nuria; Garcia de Herreros, Antonio; Aloy, Patrick 分享 收藏 Impact of DNA methylation on 3D genome structureDNA甲基化对三维基因组结构的影响Buitrago, Diana; Labrador, Mireia; Arcon, Juan Pablo; Lema, Rafael; Flores, Oscar; Esteve-Codina, Anna; Blanc, Julie; Villegas, Nuria; Bellido, David; Gut, Marta; Dans, Pablo D.; Heath, Simon C.; Gut, Ivo G.; Heath, Isabelle Brun; Orozco, Modesto 分享 收藏 分享 收藏 Bioactivity Profile Similarities to Expand the Repertoire of COVID-19 DrugsDuran-Frigola, Miquel; Bertoni, Martino; Blanco, Roi; Martinez, Victor; Pauls, Eduardo; Alcalde, Victor; Turon, Gemma; Villegas, Nuria; Fernandez-Torras, Adria; Pons, Carles; Mateo, Lidia; Guitart-Pla, Oriol; Badia-i-Mompel, Pau; Gimeno, Aleix; Soler, Nicolas; Brun-Heath, Isabelle; Zaragoza, Hugo; Aloy, Patrick 分享 收藏 分享 收藏 分享 收藏 Hsp70 and Hsp40 inhibit an inter-domain interaction necessary for transcriptional activity in the androgen receptor (vol 10, 3562, 2019)Eftekharzadeh, Bahareh; Banduseela, Varuna C.; Chiesa, Giulio; Martinez-Cristobal, Paula; Rauch, Jennifer N.; Nath, Samir R.; Schwarz, Daniel M. C.; Shao, Hao; Marin-Argany, Marta; Di Sanza, Claudio; Giorgetti, Elisa; Yu, Zhigang; Pierattelli, Roberta; Felli, Isabella C.; Brun-Heath, Isabelle; Garcia, Jesus; Nebreda, Angel R.; Gestwicki, Jason E.; Lieberman, Andrew P.; Salvatella, Xavier 分享 收藏 Nucleosome Dynamics: a new tool for the dynamic analysis of nucleosome positioningBuitrago, Diana; Codo, Laia; Illa, Ricard; de Jorge, Pau; Battistini, Federica; Flores, Oscar; Bayarri, Genis; Royo, Romina; Del Pino, Marc; Heath, Simon; Hospital, Adam; Lluis Gelpi, Josep; Brun Heath, Isabelle; Orozco, Modesto 分享 收藏 Hsp70 and Hsp40 inhibit an inter-domain interaction necessary for transcriptional activity in the androgen receptorEftekharzadeh, Bahareh; Banduseela, Varuna C.; Chiesa, Giulio; Martinez-Cristobal, Paula; Rauch, Jennifer N.; Nath, Samir R.; Schwarz, Daniel M. C.; Shao, Hao; Marin-Argany, Marta; Di Sanza, Claudio; Giorgetti, Elisa; Yu, Zhigang; Pieratelli, Roberta; Felli, Isabella C.; Brun-Heath, Isabelle; Garcia, Jesus; Nebreda, Angel R.; Gestwicki, Jason E.; Lieberman, Andrew P.; Salvatella, Xavier 分享 收藏 The Origins and the Biological Consequences of the Pur/Pyr DNA•RNA AsymmetryTerrazas, Montserrat; Genna, Vito; Portella, Guillem; Villegas, Nuria; Sanchez, Dani; Arnan, Carme; Pulido-Quetglas, Carlos; Johnson, Rory; Guigo, Roderic; Brun-Heath, Isabelle; Avino, Anna; Eritja, Ramon; Orozco, Modesto 分享 收藏 分享 收藏 Oncogenic mutations at the EGFR ectodomain structurally converge to remove a steric hindrance on a kinase-coupled cryptic epitopeOrellana, Laura; Thorne, Amy H.; Lema, Rafael; Gustavsson, Johan; Parisian, Alison D.; Hospital, Adam; Cordeiro, Tiago N.; Bernado, Pau; Scott, Andrew M.; Brun-Heath, Isabelle; Lindahl, Erik; Cavenee, Webster K.; Furnari, Frank B.; Orozco, Modesto 分享 收藏 
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