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Mechanism of action deconvolution of the small-molecule pathological tau aggregation inhibitor Anle138b Hosseini-Gerami, Layla; Ficulle, Elena; Humphryes-Kirilov, Neil; Airey, David C.; Scherschel, James; Kananathan, Sarubini; Eastwood, Brian J.; Bose, Suchira; Collier, David A.; Laing, Emma; Evans, David; Broughton, Howard; Bender, Andreas 分享 收藏
A human tau seeded neuronal cell model recapitulates molecular responses associated with Alzheimer's disease Ficulle, Elena; Kananathan, Sarubini; Airey, David; Gharbi, Severine, I; Humphryes-Kirilov, Neil; Scherschel, James; Dunbar, Charlotte; Eastwood, Brian J.; Laing, Emma; Collier, David A.; Bose, Suchira 分享 收藏
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Cross-Sectional Exploration of Plasma Biomarkers of Alzheimer's Disease in Down Syndrome: Early Data from the Longitudinal Investigation for Enhancing Down Syndrome Research (LIFE-DSR) Study Hendrix, James A.; Airey, David C.; Britton, Angela; Burke, Anna D.; Capone, George T.; Chavez, Ronelyn; Chen, Jacqueline; Chicoine, Brian; Costa, Alberto C. S.; Dage, Jeffrey L.; Doran, Eric; Esbensen, Anna; Evans, Casey L.; Faber, Kelley M.; Foroud, Tatiana M.; Hart, Sarah; Haugen, Kelsey; Head, Elizabeth; Hendrix, Suzanne; Hillerstrom, Hampus; Kishnani, Priya S.; Krell, Kavita; Ledesma, Duvia Lara; Lai, Florence; Lott, Ira; Ochoa-Lubinoff, Cesar; Mason, Jennifer; Nicodemus-Johnson, Jessie; Proctor, Nicholas Kyle; Pulsifer, Margaret B.; Revta, Carolyn; Rosas, H. Diana; Rosser, Tracie C.; Santoro, Stephanie; Schafer, Kim; Scheidemantel, Thomas; Schmitt, Frederick; Skotko, Brian G.; Stasko, Melissa R.; Talboy, Amy; Torres, Amy; Wilmes, Kristi; Woodward, Jason; Zimmer, Jennifer A.; Feldman, Howard H.; Mobley, William 分享 收藏
Plasma p-tau181, p-tau217, and other blood-based Alzheimer's disease biomarkers in a multi-ethnic, community study Brickman, Adam M.; Manly, Jennifer J.; Honig, Lawrence S.; Sanchez, Danurys; Reyes-Dumeyer, Dolly; Lantigua, Rafael A.; Lao, Patrick J.; Stern, Yaakov; Vonsattel, Jean Paul; Teich, Andrew F.; Airey, David C.; Proctor, Nicholas Kyle; Dage, Jeffrey L.; Mayeux, Richard 分享 收藏
Meta-Analysis of the Alzheimer's Disease Human Brain Transcriptome and Functional Dissection in Mouse Models 阿尔茨海默病小鼠模型人脑转录组和功能解剖的Meta分析 Wan, Ying-Wooi; Al-Ouran, Rami; Mangleburg, Carl G.; Perumal, Thanneer M.; Lee, Tom, V; Allison, Katherine; Swarup, Vivek; Funk, Cory C.; Gaiteri, Chris; Allen, Mariet; Wang, Minghui; Neuner, Sarah M.; Kaczorowski, Catherine C.; Philip, Vivek M.; Howell, Gareth R.; Martini-Stoica, Heidi; Zheng, Hui; Mei, Hongkang; Zhong, Xiaoyan; Kim, Jungwoo Wren; Dawson, Valina L.; Dawson, Ted M.; Pao, Ping-Chieh; Tsai, Li-Huei; Haure-Mirande, Jean-Vianney; Ehrlich, Michelle E.; Chakrabarty, Paramita; Levites, Yona; Wang, Xue; Dammer, Eric B.; Srivastava, Gyan; Mukherjee, Sumit; Sieberts, Solveig K.; Omberg, Larsson; Dang, Kristen D.; Eddy, James A.; Snyder, Phil; Chae, Yooree; Amberkar, Sandeep; Wei, Wenbin; Hide, Winston; Preuss, Christoph; Ergun, Ayla; Ebert, Phillip J.; Airey, David C.; Mostafavi, Sara; Yu, Lei; Klein, Hans-Ulrich; Carter, Gregory W.; Collier, David A.; Golde, Todd E.; Levey, Allan, I; Bennett, David A.; Estrada, Karol; Townsend, T. Matthew; Zhang, Bin; Schadt, Eric; De Jager, Philip L.; Price, Nathan D.; Ertekin-Taner, Nilufer; Liu, Zhandong; Shulman, Joshua M.; Mangravite, Lara M.; Logsdon, Benjamin A. 分享 收藏
Cerebrospinal fluid p-tau217 performs better than p-tau181 as a biomarker of Alzheimer's disease Janelidze, Shorena; Stomrud, Erik; Smith, Ruben; Palmqvist, Sebastian; Mattsson, Niklas; Airey, David C.; Proctor, Nicholas K.; Chai, Xiyun; Shcherbinin, Sergey; Sims, John R.; Triana-Baltzer, Gallen; Theunis, Clara; Slemmon, Randy; Mercken, Marc; Kolb, Hartmuth; Dage, Jeffrey L.; Hansson, Oskar 分享 收藏
Diagnostic value of plasma phosphorylated tau181 in Alzheimer's disease and frontotemporal lobar degeneration 血浆磷酸化tau181在阿尔茨海默病和额颞叶变性中的诊断价值 Thijssen, Elisabeth H.; La Joie, Renaud; Wolf, Amy; Strom, Amelia; Wang, Ping; Iaccarino, Leonardo; Bourakova, Viktoriya; Cobigo, Yann; Heuer, Hilary; Spina, Salvatore; VandeVrede, Lawren; Chai, Xiyun; Proctor, Nicholas K.; Airey, David C.; Shcherbinin, Sergey; Duggan Evans, Cynthia; Sims, John R.; Zetterberg, Henrik; Blennow, Kaj; Karydas, Anna M.; Teunissen, Charlotte E.; Kramer, Joel H.; Grinberg, Lea T.; Seeley, William W.; Rosen, Howie; Boeve, Bradley F.; Miller, Bruce L.; Rabinovici, Gil D.; Dage, Jeffrey L.; Rojas, Julio C.; Boxer, Adam L. 分享 收藏
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Genome-wide RNAseq study of the molecular mechanisms underlying microglia activation in response to pathological tau perturbation in the rTg4510 tau transgenic animal model Wang, Hong; Li, Yupeng; Ryder, John W.; Hole, Justin T.; Ebert, Philip J.; Airey, David C.; Qian, Hui-Rong; Logsdon, Benjamin; Fisher, Alice; Ahmed, Zeshan; Murray, Tracey K.; Cavallini, Annalisa; Bose, Suchira; Eastwood, Brian J.; Collier, David A.; Dage, Jeffrey L.; Miller, Bradley B.; Merchant, Kalpana M.; O'Neill, Michael J.; Demattos, Ronald B. 分享 收藏
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Plasma phospho-tau181 increases with Alzheimer's disease clinical severity and is associated with tau- and amyloid-positron emission tomography 血浆phospho-tau181随着阿尔茨海默病临床严重程度的增加而增加，并与tau和淀粉样蛋白正电子发射断层扫描相关 Mielke, Michelle M.; Hagen, Clinton E.; Xu, Jing; Chai, Xiyun; Vemuri, Prashanthi; Lowe, Val J.; Airey, David C.; Knopman, David S.; Roberts, Rosebud O.; Machulda, Mary M.; Jack, Clifford R., Jr.; Petersen, Ronald C.; Dage, Jeffrey L. 分享 收藏
Gene Expression and Pharmacodynamic Changes in 1,760 Systemic Lupus Erythematosus Patients From Two Phase III Trials of BAFF Blockade With Tabalumab Hoffman, Robert W.; Merrill, Joan T.; Alarcon-Riquelme, Marta M. E.; Petri, Michelle; Dow, Ernst R.; Nantz, Eric; Nisenbaum, Laura K.; Schroeder, Krista M.; Komocsar, Wendy J.; Perumal, Narayanan B.; Linnik, Matthew D.; Airey, David C.; Liu, Yushi; Rocha, Guilherme V.; Higgs, Richard E. 分享 收藏
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Levels of tau protein in plasma are associated with neurodegeneration and cognitive function in a population-based elderly cohort 基于人群的老年人群血浆tau蛋白水平与神经退行性变和认知功能相关 Dage, Jeffrey L.; Wennberg, Alexandra M. V.; Airey, David C.; Hagen, Clinton E.; Knopmand, David. S.; Machulda, Mary M.; Roberts, Rosebud O.; Jack, Clifford R., Jr.; Petersen, Ronald C.; Mielke, Michelle M. 分享 收藏
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BrainSeq: Neurogenomics to Drive Novel Target Discovery for Neuropsychiatric Disorders Schubert, Christian R.; O'Donnell, Patricio; Quan, Jie; Wendland, Jens R.; Xi, Hualin S.; Winslow, Ashley R.; Domenici, Enrico; Essioux, Laurent; Kam-Thong, Tony; Airey, David C.; Calley, John N.; Collier, David A.; Wang, Hong; Eastwood, Brian; Ebert, Philip; Liu, Yushi; Nisenbaum, Laura; Ruble, Cara; Scherschel, James; Smith, Ryan Matthew; Qian, Hui-Rong; Merchant, Kalpana; Didriksen, Michael; Matsumoto, Mitsuyuki; Saito, Takeshi; Brandon, Nicholas J.; Cross, Alan J.; Wang, Qi; Manji, Husseini; Kolb, Hartmuth; Furey, Maura; Drevets, Wayne C.; Shin, Joo Heon; Jaffe, Andrew E.; Jia, Yankai; Straub, Richard E.; Deep-Soboslay, Amy; Hyde, Thomas M.; Kleinman, Joel E.; Weinberger, Daniel R. 分享 收藏
Neuronal ablation of p-Akt at Ser473 leads to altered 5-HT1A/2A receptor function Saunders, Christine; Siuta, Michael; Robertson, Sabrina D.; Davis, Adeola R.; Sauer, Jennifer; Matthies, Heinrich J. G.; Gresch, Paul J.; Airey, David C.; Lindsley, Craig W.; Schetz, John A.; Niswender, Kevin D.; Veenstra-Vanderweele, Jeremy M.; Galli, Aurelio 分享 收藏
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