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Role of WISP1 in Stellate Cell Migration and Liver Fibrosis WISP1在星状细胞迁移和肝纤维化中的作用 Gonzalez, Daniela; Campos, Gisela; Puetter, Larissa; Friebel, Adrian; Holland, Christian H.; Hollaender, Leonhard; Ghallab, Ahmed; Hobloss, Zaynab; Myllys, Maiju; Hoehme, Stefan; Meindl-Beinker, Nadja M.; Dooley, Steven; Marchan, Rosemarie; Weiss, Thomas S.; Hengstler, Jan G.; Godoy, Patricio 分享 收藏
EDI3 knockdown in ER-HER2+breast cancer cells reduces tumor burden and improves survival in two mouse models of experimental metastasis 在两种实验性转移小鼠模型中，ER-HER2乳腺癌细胞中的EDI3基因敲除可降低肿瘤负荷并提高生存率 Glotzbach, Annika; Rohlf, Katharina; Gonscharow, Anastasia; Lueke, Simon; Demirci, Ozlem; Begher-Tibbe, Brigitte; Overbeck, Nina; Reinders, Jorg; Cadenas, Cristina; Hengstler, Jan G.; Edlund, Karolina; Marchan, Rosemarie 分享 收藏
Inhibition of the renal apical sodium dependent bile acid transporter prevents cholemic nephropathy in mice with obstructive cholestasis Ghallab, Ahmed; Gonzalez, Daniela; Straengberg, Ellen; Hofmann, Ute; Myllys, Maiju; Hassan, Reham; Hobloss, Zaynab; Brackhagen, Lisa; Begher-Tibbe, Brigitte; Duda, Julia C.; Drenda, Carolin; Kappenberg, Franziska; Reinders, Joerg; Friebel, Adrian; Vucur, Mihael; Turajski, Monika; Seddek, Abdel-latief; Abbas, Tahany; Abdelmageed, Noha; Morad, Samy A. F.; Morad, Walaa; Hamdy, Amira; Albrecht, Wiebke; Kittana, Naim; Assali, Mohyeddin; Vartak, Nachiket; Thriel, Christoph van; Sous, Ansam; Nell, Patrick; Villar-Fernandez, Maria; Cadenas, Cristina; Genc, Erhan; Marchan, Rosemarie; Luedde, Tom; Akerblad, Peter; Mattsson, Jan; Marschall, Hanns-Ulrich; Hoehme, Stefan; Stirnimann, Guido; Schwab, Matthias; Boor, Peter; Amann, Kerstin; Schmitz, Jessica; Braesen, Jan H.; Rahnenfuehrer, Joerg; Edlund, Karolina; Karpen, Saul J.; Simbrunner, Benedikt; Reiberger, Thomas; Mandorfer, Mattias; Trauner, Michael; Dawson, Paul A.; Lindstroem, Erik; Hengstler, Jan G. 分享 收藏
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Basic concepts of mixture toxicity and relevance for risk evaluation and regulation Bloch, Denise; Diel, Patrick; Epe, Bernd; Hellwig, Michael; Lampen, Alfonso; Mally, Angela; Marko, Doris; Villar Fernandez, Maria A.; Guth, Sabine; Roth, Angelika; Marchan, Rosemarie; Ghallab, Ahmed; Cadenas, Cristina; Nell, Patrick; Vartak, Nachiket; van Thriel, Christoph; Luch, Andreas; Schmeisser, Sebastian; Herzler, Matthias; Landsiedel, Robert; Leist, Marcel; Marx-Stoelting, Philip; Tralau, Tewes; Hengstler, Jan G. 分享 收藏
Inhibiting the glycerophosphodiesterase EDI3 in ER-HER2+breast cancer cells resistant to HER2-targeted therapy reduces viability and tumour growth Keller, Magdalena; Rohlf, Katharina; Glotzbach, Annika; Leonhardt, Gregor; Lueke, Simon; Derksen, Katharina; Demirci, Oezlem; Goecener, Defne; AlWahsh, Mohammad; Lambert, Joerg; Lindskog, Cecilia; Schmidt, Marcus; Brenner, Walburgis; Baumann, Matthias; Zent, Eldar; Zischinsky, Mia-Lisa; Hellwig, Birte; Madjar, Katrin; Rahnenfuehrer, Joerg; Overbeck, Nina; Reinders, Joerg; Cadenas, Cristina; Hengstler, Jan. G. G.; Edlund, Karolina; Marchan, Rosemarie 分享 收藏
Identification of an FXR-modulated liver-intestine hybrid state in iPSC-derived hepatocyte-like cells Nell, Patrick; Kattler, Kathrin; Feuerborn, David; Hellwig, Birte; Rieck, Adrian; Salhab, Abdulrahman; Lepikhov, Konstantin; Gasparoni, Gilles; Thomitzek, Antonia; Belgasmi, Katharina; Bluethgen, Nils; Morkel, Markus; Kueppers-Munther, Barbara; Godoy, Patricio; Hay, David C.; Cadenas, Cristina; Marchan, Rosemarie; Vartak, Nachiket; Edlund, Karolina; Rahnenfuehrer, Joerg; Walter, Joern; Hengstler, Jan G. 分享 收藏
High Accuracy Classification of Developmental Toxicants by In Vitro Tests of Human Neuroepithelial and Cardiomyoblast Differentiation Seidel, Florian; Cherianidou, Anna; Kappenberg, Franziska; Marta, Miriam; Dreser, Nadine; Blum, Jonathan; Waldmann, Tanja; Bluthgen, Nils; Meisig, Johannes; Madjar, Katrin; Henry, Margit; Rotshteyn, Tamara; Scholtz-Illigens, Andreas; Marchan, Rosemarie; Edlund, Karolina; Leist, Marcel; Rahnenfuehrer, Joerg; Sachinidis, Agapios; Hengstler, Jan Georg 分享 收藏
Inhibition of cytochrome P450 enhances the nephro- and hepatotoxicity of ochratoxin A Hassan, Reham; Gonzalez, Daniela; Hobloss, Zaynab; Brackhagen, Lisa; Myllys, Maiju; Friebel, Adrian; Seddek, Abdel-Latif; Marchan, Rosemarie; Cramer, Benedikt; Humpf, Hans-Ulrich; Hoehme, Stefan; Degen, Gisela H.; Hengstler, Jan G.; Ghallab, Ahmed 分享 收藏
Colchicine overdose impairs the capacity of Kupffer cells to clear foreign particles and endotoxins Hassan, Reham; Myllys, Maiju; Brackhagen, Lisa; Hobloss, Zaynab; Gonzalez, Daniela; Seddek, Abdel-latif; Friebel, Adrian; Hoehme, Stefan; Marchan, Rosemarie; Trauner, Michael; Hengstler, Jan G.; Ghallab, Ahmed 分享 收藏
In vitro/in silico prediction of drug induced steatosis in relation to oral doses and blood concentrations by the Nile Red assay Brecklinghaus, Tim; Albrecht, Wiebke; Duda, Julia; Kappenberg, Franziska; Gruendler, Lisa; Edlund, Karolina; Marchan, Rosemarie; Ghallab, Ahmed; Cadenas, Cristina; Rieck, Adrian; Vartak, Nachiket; Tolosa, Laia; Castell, Jose, V; Gardner, Iain; Halilbasic, Emina; Trauner, Michael; Ullrich, Anett; Zeigerer, Anja; Turgunbayer, Oezlem Demirci; Damm, Georg; Seehofer, Daniel; Rahnenfuhrer, Joerg; Hengstler, Jan G. 分享 收藏
Hypoalbuminemia affects the spatio-temporal tissue distribution of ochratoxin A in liver and kidneys: consequences for organ toxicity Hassan, Reham; Friebel, Adrian; Brackhagen, Lisa; Hobloss, Zaynab; Myllys, Maiju; Gonzalez, Daniela; Albrecht, Wiebke; Mohammed, Elsayed S., I; Seddek, Abdel-Latif; Marchan, Rosemarie; Cadenas, Cristina; Cramer, Benedikt; Humpf, Hans-Ulrich; Hartl, Lukas; Simbrunner, Benedikt; Reiberger, Thomas; Trauner, Michael; Hoehme, Stefan; Degen, Gisela H.; Hengstler, Jan G.; Ghallab, Ahmed 分享 收藏
Interruption of bile acid uptake by hepatocytes after acetaminophen overdose ameliorates hepatotoxicity Ghallab, Ahmed; Hassan, Reham; Hofmann, Ute; Friebel, Adrian; Hobloss, Zaynab; Brackhagen, Lisa; Begher-Tibbe, Brigitte; Myllys, Maiju; Reinders, Joerg; Overbeck, Nina; Sezgin, Selahaddin; Zuehlke, Sebastian; Seddek, Abdel-Latif; Murad, Walaa; Brecklinghaus, Tim; Kappenberg, Franziska; Rahnenfuehrer, Joerg; Gonzalez, Daniela; Goldring, Christopher; Copple, Ian M.; Marchan, Rosemarie; Longerich, Thomas; Vucur, Mihael; Luedde, Tom; Urban, Stephan; Canbay, Ali; Schreiter, Thomas; Trauner, Michael; Akakpo, Jephte Y.; Olyaee, Mojtaba; Curry, Steven C.; Sowa, Jan-Peter; Jaeschke, Hartmut; Hoehme, Stefan; Hengstler, Jan G. 分享 收藏
Classification of Developmental Toxicants in a Human iPSC Transcriptomics-Based Test Cherianidou, Anna; Seidel, Florian; Kappenberg, Franziska; Dreser, Nadine; Blum, Jonathan; Waldmann, Tanja; Bluethgen, Nils; Meisig, Johannes; Madjar, Katrin; Henry, Margit; Rotshteyn, Tamara; Marchan, Rosemarie; Edlund, Karolina; Leist, Marcel; Rahnenfuhrer, Joerg; Sachinidis, Agapios; Hengstler, Jan G. 分享 收藏
Impact of Biological and Lifestyle Factors on Cognitive Aging and Work Ability in the Dortmund Vital Study: Protocol of an Interdisciplinary, Cross-sectional, and Longitudinal Study Gajewski, Patrick D.; Getzmann, Stephan; Brode, Peter; Burke, Michael; Cadenas, Cristina; Capellino, Silvia; Claus, Maren; Genc, Erhan; Golka, Klaus; Hengstler, Jan G.; Kleinsorge, Thomas; Marchan, Rosemarie; Nitsche, Michael A.; Reinders, Jorg; van Thriel, Christoph; Watzl, Carsten; Wascher, Edmund 分享 收藏
Toxicogenomics directory of chemically exposed human hepatocytes (vol 88, pg 2261, 2014) 化学暴露的人类肝细胞的毒理基因组学目录 (第88卷，2261页，2014) Grinberg, Marianna; Stoeber, Regina M.; Edlund, Karolina; Rempel, Eugen; Godoy, Patricio; Reif, Raymond; Widera, Agata; Madjar, Katrin; Schmidt-Heck, Wolfgang; Marchan, Rosemarie; Sachinidis, Agapios; Spitkovsky, Dimitry; Hescheler, Juergen; Carmo, Helena; Arbo, Marcelo D.; van de Water, Bob; Wink, Steven; Vinken, Mathieu; Rogiers, Vera; Escher, Sylvia; Hardy, Barry; Mitic, Dragana; Apic, Gordana; Myatt, Glenn; Waldmann, Tanja; Mardinoglu, Adil; Damm, Georg; Seehofer, Daniel; Nuessler, Andreas; Weiss, Thomas S.; Oberemm, Axel; Lampen, Alfons; Schaap, Mirjam M.; Luijten, Mirjam; van Steeg, Harry; Thasler, Wolfgang E.; Kleinjans, Jos C. S.; Stierum, Rob H.; Leist, Marcel; Rahnenfuehrer, Joerg; Hengstler, Jan G. 分享 收藏
The hepatocyte export carrier inhibition assay improves the separation of hepatotoxic from non-hepatotoxic compounds Brecklinghaus, Tim; Albrecht, Wiebke; Kappenberg, Franziska; Duda, Julia; Vartak, Nachiket; Edlund, Karolina; Marchan, Rosemarie; Ghallab, Ahmed; Cadenas, Cristina; Gunther, Georgia; Leist, Marcel; Zhang, Mian; Gardner, Iain; Reinders, Jorg; Russel, Frans G. M.; Foster, Alison J.; Williams, Dominic P.; Damle-Vartak, Amruta; Grandits, Melanie; Ecker, Gerhard; Kittana, Naim; Rahnenfuehrer, Jorg; Hengstler, Jan G. 分享 收藏
Spatio-Temporal Multiscale Analysis of Western Diet-Fed Mice Reveals a Translationally Relevant Sequence of Events during NAFLD Progression Ghallab, Ahmed; Myllys, Maiju; Friebel, Adrian; Duda, Julia; Edlund, Karolina; Halilbasic, Emina; Vucur, Mihael; Hobloss, Zaynab; Brackhagen, Lisa; Begher-Tibbe, Brigitte; Hassan, Reham; Burke, Michael; Genc, Erhan; Frohwein, Lynn Johann; Hofmann, Ute; Holland, Christian H.; Gonzalez, Daniela; Keller, Magdalena; Seddek, Abdel-latif; Abbas, Tahany; Mohammed, Elsayed S. I.; Teufel, Andreas; Itzel, Timo; Metzler, Sarah; Marchan, Rosemarie; Cadenas, Cristina; Watzl, Carsten; Nitsche, Michael A.; Kappenberg, Franziska; Luedde, Tom; Longerich, Thomas; Rahnenfuehrer, Joerg; Hoehme, Stefan; Trauner, Michael; Hengstler, Jan G. 分享 收藏
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