Rodrigo Ochoa - Publications, H-index & Citations

Rodrigo Ochoa

Novo Nordisk A/S

16H指数

87论文数

656被引数

收录论文 22

发表时间

Peptide cheminformatics tools: making computational tasks accessible in peptide drug discovery

Drug Discovery Today

IF7.5

2026-01-21

OAAI

Vanessa Erckes; Massina Abderrahmane; Maud Jusot; Christian Steuer; Rodrigo Ochoa

Trimerization domain-interfering peptide inhibits EML4-ALK condensate formation, fusion-dependent signaling, and cell growth 三聚化结构域干扰肽抑制EML4-ALK凝聚体形成、融合依赖性信号传导和细胞生长

MOLECULAR BIOLOGY OF THE CELL

IF2.7

2025-10-01

OAAI

Scheller, Kyle; Zhou, Xin; Li, Kun; Jiang, Lan; Ochoa, Rodrigo; Cossio, Pilar; Wu, Lizi; Guan, Juan

Targeting 7KCh-Induced Cell Death Response Mediated by p38, P2X7 and GSDME in Retinal Pigment Epithelium Cells with Sterculic Acid

PHARMACEUTICS

IF5.5

2023-11-05

OAAI

Pariente, Ana; Pelaez, Rafael; Ochoa, Rodrigo; Perez-Sala, Alvaro; Villanueva-Martinez, Angela; Bobadilla, Miriam; Larrayoz, Ignacio M.

pyPept: a python library to generate atomistic 2D and 3D representations of peptides pyPept: 一个python库，用于生成肽的原子2D和3D表示

JOURNAL OF CHEMINFORMATICS

IF5.7

2023-09-12

OAAI

Ochoa, Rodrigo; Brown, J. B.; Fox, Thomas

In vitro and in silico study of an exclusive insertion in the nicotinamide/nicotinate mononucleotide adenylyltransferase from Leishmania braziliensis

HELIYON

IF3.6

2022-12-01

OAAI

Ortiz-Joya, Lesly Johanna; Contreras Rodriguez, Luis Ernesto; Ochoa, Rodrigo; Ramirez Hernandez, Maria Helena

Protocol for iterative optimization of modified peptides bound to protein targets

JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

IF3.1

2022-10-19

OAAI

Ochoa, Rodrigo; Cossio, Pilar; Fox, Thomas

BILN: A Human-Readable Line Notation for Complex Peptides

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2022-08-19

PREAI

Fox, Thomas; Bieler, Michael; Haebel, Peter; Ochoa, Rodrigo; Peters, Stefan; Weber, Alexander

In Silico, In Vitro, and Pharmacokinetic Studies of UBMC-4, a Potential Novel Compound for Treating against Trypanosoma cruzi

PATHOGENS

IF3.3

2022-05-24

OAAI

Bustamante, Christian; Diez-Mejia, Andres Felipe; Arbelaez, Natalia; Soares, Maurilio Jose; Robledo, Sara M.; Ochoa, Rodrigo; Varela-M., Ruben E.; Marin-Villa, Marcel

Multiple-Allele MHC Class II Epitope Engineering by a Molecular Dynamics-Based Evolution Protocol

FRONTIERS IN IMMUNOLOGY

IF5.9

2022-04-27

OAAI

Ochoa, Rodrigo; Lunardelli, Victoria Alves Santos; Rosa, Daniela Santoro; Laio, Alessandro; Cossio, Pilar

Predictive Biomarkers of Age-Related Macular Degeneration Response to Anti-VEGF Treatment

JOURNAL OF PERSONALIZED MEDICINE

IF3

2021-12-08

OAAI

Oca, Ana I.; Perez-Sala, Alvaro; Pariente, Ana; Ochoa, Rodrigo; Velilla, Sara; Pelaez, Rafael; Larrayoz, Ignacio M.

Impact of Structural Observables From Simulations to Predict the Effect of Single-Point Mutations in MHC Class II Peptide Binders 模拟的结构可观察量对预测MHC II类肽结合物单点突变影响的影响

FRONTIERS IN MOLECULAR BIOSCIENCES

IF4

2021-03-30

OAAI

Ochoa, Rodrigo; Laskowski, Roman A.; Thornton, Janet M.; Cossio, Pilar

PepFun: Open Source Protocols for Peptide-Related Computational Analysis

MOLECULES

IF4.6

2021-03-16

OAAI

Ochoa, Rodrigo; Cossio, Pilar

PARCE: Protocol for Amino acid Refinement through Computational Evolution

COMPUTER PHYSICS COMMUNICATIONS

IF3.4

2021-03-01

OAAI

Ochoa, Rodrigo; Soler, Miguel A.; Laio, Alessandro; Cossio, Pilar

Genome-Wide Transcriptomic Analysis Identifies Pathways Regulated by Sterculic Acid in Retinal Pigmented Epithelium Cells

CELLS

IF5.2

2020-05-11

OAAI

Pariente, Ana; Perez-Sala, Alvaro; Ochoa, Rodrigo; Pelaez, Rafael; Larrayoz, Ignacio M.

Repurposing of known drugs for leishmaniasis treatment using bioinformatic predictions, in vitro validations and pharmacokinetic simulations

JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

IF3.1

2019-10-14

PREAI

Bustamante, Christian; Ochoa, Rodrigo; Asela, Claudia; Muskus, Carlos

Predicting the Affinity of Peptides to Major Histocompatibility Complex Class II by Scoring Molecular Dynamics Simulations

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2019-07-10

OAAI

Ochoa, Rodrigo; Laio, Alessandro; Cossio, Pilar

Anti-Herpetic, Anti-Dengue and Antineoplastic Activities of Simple and Heterocycle-Fused Derivatives of Terpenyl-1,4-Naphthoquinone and 1,4-Anthraquinone

MOLECULES

IF4.6

2019-04-02

OAAI

Roa-Linares, Vicky C.; Miranda-Brand, Yaneth; Tangarife-Castano, Veronica; Ochoa, Rodrigo; Garcia, Pablo A.; Angeles Castro, M.; Betancur-Galvis, Liliana; San Feliciano, Arturo

Toxic Activity, Molecular Modeling and Docking Simulations of Bacillus thuringiensis Cry11 Toxin Variants Obtained via DNA Shuffling

FRONTIERS IN MICROBIOLOGY

IF4.5

2018-10-17

OAAI

Mauricio Florez, Alvaro; Orlando Suarez-Barrera, Miguel; Morales, Gloria M.; Viviana Rivera, Karen; Orduz, Sergio; Ochoa, Rodrigo; Guerra, Diego; Muskus, Carlos

Identification of a RAC/AKT-like gene in Leishmania parasites as a putative therapeutic target in leishmaniasis

PARASITES & VECTORS

IF3.5

2017-10-10

OAAI

Varela-M, Ruben E.; Ochoa, Rodrigo; Muskus, Carlos E.; Muro, Antonio; Mollinedo, Faustino

Drug search for leishmaniasis: a virtual screening approach by grid computing

JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

IF3.1

2016-07-20

PREAI

Ochoa, Rodrigo; Watowich, Stanley J.; Florez, Andres; Mesa, Carol V.; Robledo, Sara M.; Muskus, Carlos

研究方向