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N

Naomi Nakagata

kumamoto university
H指数:53
被引数:9,973

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Inability of α-cyclodextrins to accommodate cholesterol potentially underlies their lack of efficacy and ototoxicity in Niemann-Pick disease type C treatment

α-环糊精无法容纳胆固醇，这可能是其治疗尼曼-匹克C型病缺乏疗效和具有耳毒性的潜在原因。

Scientific Reports
IF3.9
2025-08-220
OAAI
Yusei Yamada; Mayuko Tanaka; Yusei Ikeda; Yuki Kondo; Toru Takeo; Naomi Nakagata; Toru Miwa; Hiroki Takeda; Yorihisa Orita; Keiichi Motoyama; Taishi Higashi; Hidetoshi Arima; Takahiro Seki; Yuki Kurauchi; Hiroshi Katsuki; Katsumi Higaki; Kotaro Matsusaka; Kentaro Minami; Naoki Yoshikawa; Ryuji Ikeda; Muneaki Matsuo; Tetsumi Irie; Yoichi Ishitsuka
GDE5/Gpcpd1 activity determines phosphatidylcholine composition in skeletal muscle and regulates contractile force in mice
COMMUNICATIONS BIOLOGY
IF5.1
2024-05-203
OAAI
Aisyah, Rahmawati; Ohshima, Noriyasu; Watanabe, Daiki; Nakagawa, Yoshiko; Sakuma, Tetsushi; Nitschke, Felix; Nakamura, Minako; Sato, Koji; Nakahata, Kaori; Yokoyama, Chihiro; Marchioni, Charlotte R.; Kumrungsee, Thanutchaporn; Shimizu, Takahiko; Sotomaru, Yusuke; Takeo, Toru; Nakagata, Naomi; Izumi, Takashi; Miura, Shinji; Minassian, Berge A.; Yamamoto, Takashi; Wada, Masanobu; Yanaka, Noriyuki
Different solubilizing ability of cyclodextrin derivatives for cholesterol in Niemann-Pick disease type C treatment
CLINICAL AND TRANSLATIONAL MEDICINE
IF6.8
2023-08-246
OAAI
Yamada, Yusei; Fukaura-Nishizawa, Madoka; Nishiyama, Asami; Ishii, Akira; Kawata, Tatsuya; Shirakawa, Aina; Tanaka, Mayuko; Kondo, Yuki; Takeo, Toru; Nakagata, Naomi; Miwa, Toru; Takeda, Hiroki; Orita, Yorihisa; Motoyama, Keiichi; Higashi, Taishi; Arima, Hidetoshi; Seki, Takahiro; Kurauchi, Yuki; Katsuki, Hiroshi; Higaki, Katsumi; Minami, Kentaro; Yoshikawa, Naoki; Ikeda, Ryuji; Matsuo, Muneaki; Irie, Tetsumi; Ishitsuka, Yoichi
Fine-tuned cholesterol solubilizer, mono-6-O-α-D-maltosyl-γ-cyclodextrin, ameliorates experimental Niemann-Pick disease type C without hearing loss
BIOMEDICINE & PHARMACOTHERAPY
IF7.5
2022-11-015
OAAI
Yamada, Yusei; Miwa, Toru; Nakashima, Masaki; Shirakawa, Aina; Ishii, Akira; Namba, Nanami; Kondo, Yuki; Takeo, Toru; Nakagata, Naomi; Motoyama, Keiichi; Higashi, Taishi; Arima, Hidetoshi; Kurauchi, Yuki; Seki, Takahiro; Katsuki, Hiroshi; Okada, Yasuyo; Ichikawa, Atsushi; Higaki, Katsumi; Hayashi, Ken; Minami, Kentaro; Yoshikawa, Naoki; Ikeda, Ryuji; Ishikawa, Yoshihide; Kajii, Tomohito; Tachii, Kyoko; Takeda, Hiroki; Orita, Yorihisa; Matsuo, Muneaki; Irie, Tetsumi; Ishitsuka, Yoichi
RUNX1-ETO (RUNX1-RUNX1T1) induces myeloid leukemia in mice in an age-dependent manner
LEUKEMIA
IF13.4
2021-06-198
OAAI
Abdallah, Mohamed Gaber; Niibori-Nambu, Akiko; Morii, Mariko; Yokomizo, Takako; Yokomizo, Tomomasa; Ideue, Takako; Kubota, Sho; Teoh, Vania Swee Imm; Mok, Michelle Meng Huang; Wang, Chelsia Qiuxia; Omar, Abdellah Ali; Tokunaga, Kenji; Iwanaga, Eisaku; Matsuoka, Masao; Asou, Norio; Nakagata, Naomi; Araki, Kimi; AboElenin, Mabrouk; Madboly, Sayed Hamada; Sashida, Goro; Osato, Motomi
Differential mode of cholesterol inclusion with 2-hydroxypropyl-cyclodextrins increases safety margin in treatment of Niemann-Pick disease type C

胆固醇与2-羟丙基-环糊精的差异模式增加了C型niemann-pick疾病治疗的安全范围

BRITISH JOURNAL OF PHARMACOLOGY
IF7.7
2021-05-1212
OAAI
Yamada, Yusei; Ishitsuka, Yoichi; Kondo, Yuki; Nakahara, Shuichi; Nishiyama, Asami; Takeo, Toru; Nakagata, Naomi; Motoyama, Keiichi; Higashi, Taishi; Arima, Hidetoshi; Kamei, Shunsuke; Shuto, Tsuyoshi; Kai, Hirofumi; Hayashino, Yuji; Sugita, Masatake; Kikuchi, Takeshi; Hirata, Fumio; Miwa, Toru; Takeda, Hiroki; Orita, Yorihisa; Seki, Takahiro; Ohta, Tomoko; Kurauchi, Yuki; Katsuki, Hiroshi; Matsuo, Muneaki; Higaki, Katsumi; Ohno, Kousaku; Matsumoto, Shirou; Era, Takumi; Irie, Tetsumi
Dysfunction of the proteoglycan Tsukushi causes hydrocephalus through altered neurogenesis in the subventricular zone in mice
SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2021-03-3116
PRE
Ito, Naofumi; Riyadh, M. Asrafuzzaman; Ahmad, Shah Adil Ishtiyaq; Hattori, Satoko; Kanemura, Yonehiro; Kiyonari, Hiroshi; Abe, Takaya; Furuta, Yasuhide; Shinmyo, Yohei; Kaneko, Naoko; Hirota, Yuki; Lupo, Giuseppe; Hatakeyama, Jun; Abdulhaleem, Felemban Athary M.; Anam, Mohammad Badrul; Yamaguchi, Masahiro; Takeo, Toru; Takebayashi, Hirohide; Takebayashi, Minoru; Oike, Yuichi; Nakagata, Naomi; Shimamura, Kenji; Holtzman, Michael J.; Takahashi, Yoshiko; Guillemot, Francois; Miyakawa, Tsuyoshi; Sawamoto, Kazunobu; Ohta, Kunimasa

研究方向

暂未获取到该数据
T
Takeo, Toru
H 指数:0论文数:1被引数:1
G
Gen Yamada
H 指数:54论文数:269被引数:1.0万
H
Hiroki Kurihara
H 指数:80论文数:430被引数:3.2万
T
Tetsumi Irie
H 指数:44论文数:383被引数:1.0万
K
Kentaro Suzuki
H 指数:34论文数:123被引数:4,582
S
Satohiro Nakao
H 指数:8论文数:33被引数:191
N
Naoaki Harada
H 指数:31论文数:155被引数:2,697
K
Kenji Okajima
H 指数:45论文数:341被引数:7,305
Y
Yoichi Ishitsuka
H 指数:22论文数:117被引数:1,393
T
Toshio Suda
H 指数:139论文数:1,069被引数:7.6万