Fulton T. Crews

University of North Carolina

H指数:83

被引数:2.6万

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Epigenetic Repression of the Serotonergic Neuron Phenotype Following Adolescent Binge Drinking Is Restored through Inhibition of Proinflammatory Signaling by Exercise and Glycyrrhizic Acid

青春期暴饮行为对血清素能神经元表型的表观遗传抑制作用可通过运动和甘草酸抑制促炎信号通路得到恢复

Journal of Neuroscience

IF4

2026-04-221

PRE

Adolescent Binge Ethanol Exposure Confers Lasting Adult Alcohol Tolerance due to Neuroimmune Activation: Reversal by Inhibition of HMGB1

青少年暴饮乙醇暴露通过神经免疫激活导致持续成年酒精耐受性：HMGB1抑制可逆转

Addiction Biology

IF2.6

2026-03-040

OAAI

Adolescent adversity persistently induces proinflammatory HMGB1 signaling and disrupts the basal forebrain cholinergic system in female rats

青少年期逆境持续诱导促炎HMGB1信号通路，并破坏雌性大鼠基底前脑胆碱能系统。

Neurobiology of Stress

IF3.6

2025-12-190

OAAI

Cortical reactive microglia activate astrocytes, increasing neurodegeneration in human alcohol use disorder

皮质反应性小胶质细胞激活星形胶质细胞，增加人类酒精使用障碍中的神经退行性变

Brain, Behavior, and Immunity

IF0

2025-10-300

PRE

In memoriam - George R. Breese, Ph.D

纪念-George R. Breese，Ph.D

NEUROPSYCHOPHARMACOLOGY

IF7.1

2024-11-190

Alcohol, HMGB1, and Innate Immune Signaling in the Brain

酒精，HMGB1和大脑中的先天免疫信号

ALCOHOL RESEARCH-CURRENT REVIEWS

IF9

2024-01-010

PRE

HMGB1 neuroimmune signaling and REST-G9a gene repression contribute to ethanol-induced reversible suppression of the cholinergic neuron phenotype

HMGB1神经免疫信号和REST-G9a基因抑制有助于乙醇诱导的胆碱能神经元表型的可逆抑制

MOLECULAR PSYCHIATRY

IF10.1

2023-07-043

OAAI

High-mobility group box 1 (HMGB1) crosses the BBB bidirectionally

高迁移率组盒1 (HMGB1) 双向穿过BBB

BRAIN BEHAVIOR AND IMMUNITY

IF7.6

2023-07-019

PRE

Targeting Persistent Changes in Neuroimmune and Epigenetic Signaling in Adolescent Drinking to Treat Alcohol Use Disorder in Adulthood

针对青少年饮酒中神经免疫和表观遗传信号的持续变化来治疗成年期的酒精使用障碍

PHARMACOLOGICAL REVIEWS

IF17.3

2023-03-019

OAAI

Indomethacin restores loss of hippocampal neurogenesis and cholinergic innervation and reduces innate immune expression and reversal learning deficits in adult male and female rats following adolescent ethanol exposure

吲哚美辛可恢复青春期乙醇暴露后成年雄性和雌性大鼠海马神经发生和胆碱能神经支配的丧失，并减少先天免疫表达和逆转学习缺陷

ALCOHOL-CLINICAL AND EXPERIMENTAL RESEARCH

IF2.7

2023-02-176

NADPH oxidase and endoplasmic reticulum stress is associated with neuronal degeneration in orbitofrontal cortex of individuals with alcohol use disorder

ADDICTION BIOLOGY

IF2.6

2022-12-104

Cholinergic REST-G9a gene repression through HMGB1-TLR4 neuroimmune signaling regulates basal forebrain cholinergic neuron phenotype

FRONTIERS IN MOLECULAR NEUROSCIENCE

IF3.8

2022-08-226

OAAI

Ethanol Induces Secretion of Proinflammatory Extracellular Vesicles That Inhibit Adult Hippocampal Neurogenesis Through G9a/GLP-Epigenetic Signaling

FRONTIERS IN IMMUNOLOGY

IF5.9

2022-05-139

OAAI

Increased alcohol self-administration following repeated Toll-like receptor 3 agonist treatment in male and female rats

PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

IF2.5

2022-05-0114

OAAI

The Toll-like receptor 7 agonist imiquimod increases ethanol self-administration and induces expression of Toll-like receptor related genes

ADDICTION BIOLOGY

IF2.6

2022-04-2210

Impact of adolescent intermittent ethanol exposure on interneurons and their surrounding perineuronal nets in adulthood

青少年间歇性乙醇暴露对成年后中间神经元及其周围神经周围网的影响

ALCOHOL-CLINICAL AND EXPERIMENTAL RESEARCH

IF2.7

2022-04-0119

Galantamine prevents and reverses neuroimmune induction and loss of adult hippocampal neurogenesis following adolescent alcohol exposure

JOURNAL OF NEUROINFLAMMATION

IF10.1

2021-09-1613

OAAI

Increased Toll-like Receptor-MyD88-NFκB-Proinflammatory neuroimmune signaling in the orbitofrontal cortex of human alcohol use disorder

ALCOHOL-CLINICAL AND EXPERIMENTAL RESEARCH

IF2.7

2021-08-2029

OAAI

Adolescent Alcohol Exposure Produces Protracted Cognitive-Behavioral Impairments in Adult Male and Female Rats

青少年酒精暴露会在成年雄性和雌性大鼠中产生长期的认知行为障碍

behavioral and brain sciences

IF2.8

2020-10-2833

OAAI

Hippocampal TNF-death receptors, caspase cell death cascades, and IL-8 in alcohol use disorder

海马TNF-死亡受体，半胱天冬酶细胞死亡级联和酒精使用障碍的IL-8

MOLECULAR PSYCHIATRY

IF10.1

2020-03-0532

OAAI

Fulton T. Crews

个人简介

教育背景

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