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收藏Structure-Activity Relationships and Discovery of (S)-5-(tert-Butyl)-11-(difluoromethoxy)-9-methoxy-2-oxo-1,2,5,6-tetrahydropyrido[2′,1′:2,3]imidazo[4,5-h]quinoline-3-carboxylic Acid (AB-161), a Novel Orally Available and Liver-Centric HBV RNA Destabilizer
Gotchev, Dimitar; Chen, Shuai; Dugan, Benjamin; Dorsey, Bruce D.; Wang, Xu; Sheraz, Muhammad; Kowalski, Rose; Liu, Fei; Tang, Sunny; Chiu, Tim; Harasym, Troy; Graves, Ingrid E.; Thi, Emily P.; Mason, Jeremy D.; Overholt, Nathan; Dugyala, Ravi; Lam, Angela M.; Cole, Andrew G.; Sofia, Michael J.
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收藏Discovery of C-Linked Nucleoside Analogues with Antiviral Activity against SARS-CoV-2发现对SARS-CoV-2具有抗病毒活性的C-连接核苷类似物
Mesaros, Eugen F.; Dugan, Benjamin J.; Gao, Min; Sheraz, Muhammad; McGovern-Gooch, Kayleigh; Xu, Fran; Fan, Kristi Yi; Nguyen, Duyan; Kultgen, Steven G.; Lindstrom, Aaron; Stever, Kim; Tercero, Breanna; Binder, Randall J.; Liu, Fei; Micolochick Steuer, Holly M.; Mani, Nagraj; Harasym, Troy O.; Thi, Emily P.; Cuconati, Andrea; Dorsey, Bruce D.; Cole, Andrew G.; Lam, Angela M.; Sofia, Michael J.
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收藏Preclinical Antiviral and Safety Profiling of the HBV RNA Destabilizer AB-161
Lam, Angela M.; Dugyala, Ravi R.; Sheraz, Muhammed; Liu, Fei; Thi, Emily P.; Graves, Ingrid E.; Cuconati, Andrea; Steuer, Holly Micolochick; Ardzinski, Andrzej; Overholt, Nathan; Mason, Jeremy D.; Gotchev, Dimitar; Cole, Andrew G.; Harasym, Troy O.; Sofia, Michael J.
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收藏Activation of Stimulator of Interferon Genes in Hepatocytes Suppresses the Replication of Hepatitis B Virus肝细胞干扰素基因刺激因子的激活抑制乙型肝炎病毒的复制
Guo, Fang; Tang, Liudi; Shu, Sainan; Sehgal, Mohit; Sheraz, Muhammad; Liu, Bowei; Zhao, Qiong; Cheng, Junjun; Zhao, Xuesen; Zhou, Tianlun; Chang, Jinhong; Guo, Ju-Tao
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收藏HBV core protein allosteric modulators differentially alter cccDNA biosynthesis from de novo infection and intracellular amplification pathways
Guo, Fang; Zhao, Qiong; Sheraz, Muhammad; Cheng, Junjun; Qi, Yonghe; Su, Qing; Cuconati, Andrea; Wei, Lai; Du, Yanming; Li, Wenhui; Chang, Jinhong; Guo, Ju-Tao
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