Harald John

bundeswehr institute of pharmacology and toxicology

H指数:32

被引数:3,371

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Organophosphate pesticide poisoning: benefits and limitations of oxime therapy

有机磷酸酯类农药中毒：肟类药物治疗的优势与局限性

Clinical Toxicology

IF3.3

2026-08-260

PRE

Keratin adducts in human hair prove exposure to sulfur mustard in a real case of poisoning and indicate exposure to sesquimustard and O-lost in vitro

人发中的角蛋白加合物证实了硫芥子气中毒的真实案例暴露，并表明体外暴露于赛克芥子气（sesquimustard）和O-丢失（O-lost）。

Archives of Toxicology

IF6.9

2026-02-070

PREAI

Toxic Tear Gas 2-Chloroacetophenone (CN) Forms Adducts With Endogenous Plasma Thiols In Vitro Valuable as Biomarkers of Exposure

毒害性催泪瓦斯2-氯苯乙酮（CN）在体外与内源性血浆硫醇形成加合物，可作为暴露的生物标志物

Drug Testing and Analysis

IF2.7

2025-11-040

OAAI

Phosphonylated tyrosine and cysteine disulfide adducts both generated from immunoglobulin G and human serum albumin indicate exposure to the nerve agent VX in vitro

ANALYTICAL AND BIOANALYTICAL CHEMISTRY

IF3.8

2025-02-010

OAAI

The blistering warfare agent O-mustard (agent T) generates protein-adducts with human serum albumin useful for biomedical verification of exposure and forms intramolecular cross-links

ANALYTICAL AND BIOANALYTICAL CHEMISTRY

IF3.8

2024-08-311

OAAI

Effects of the nerve agent VX on hiPSC-derived motor neurons

ARCHIVES OF TOXICOLOGY

IF6.9

2024-03-300

OAAI

The phosphylated butyrylcholinesterase-derived tetrapeptide GlyGluSerAla proves exposure to organophosphorus agents with enantioselectivity

磷酸化的丁酰胆碱酯酶衍生的四肽GlyGluSerAla证明了对映选择性的有机磷试剂的暴露

ARCHIVES OF TOXICOLOGY

IF6.9

2024-01-241

PRE

Evidence of nerve agent VX exposure in rat plasma by detection of albumin-adducts in vitro and in vivo

通过体外和体内检测白蛋白加合物证明大鼠血浆中神经毒剂VX暴露的证据

ARCHIVES OF TOXICOLOGY

IF6.9

2023-06-0110

OAAI

Isolation of human TRPA1 channel from transfected HEK293 cells and identification of alkylation sites after sulfur mustard exposure

ARCHIVES OF TOXICOLOGY

IF6.9

2022-11-122

OAAI

Highly stable peptide adducts from hard keratins as biomarkers to verify local sulfur mustard exposure of hair by high-resolution mass spectrometry

ARCHIVES OF TOXICOLOGY

IF6.9

2022-05-165

OAAI

Nontargeted High-Resolution Mass Spectrometric Workflow for the Detection of Butyrylcholinesterase-Derived Adducts with Organophosphorus Toxicants and Structural Characterization of Their Phosphyl Moiety after In-Source Fragmentation

ANALYTICAL CHEMISTRY

IF6.7

2022-01-189

Alkylation of rabbit muscle creatine kinase surface methionine residues inhibits enzyme activity in vitro

ARCHIVES OF TOXICOLOGY

IF6.9

2021-08-161

OAAI

Alkylated albumin-derived dipeptide C(-HETE)P derivatized by propionic anhydride as a biomarker for the verification of poisoning with sulfur mustard

ANALYTICAL AND BIOANALYTICAL CHEMISTRY

IF3.8

2021-07-028

OAAI

Alkylated epidermal creatine kinase as a biomarker for sulfur mustard exposure: comparison to adducts of albumin and DNA in an in vivo rat study

ARCHIVES OF TOXICOLOGY

IF6.9

2021-02-2611

OAAI

Poisoning by organophosphorus nerve agents and pesticides: An overview of the principle strategies and current progress of mass spectrometry-based procedures for verification

JOURNAL OF MASS SPECTROMETRY AND ADVANCES IN THE CLINICAL LAB

IF3.4

2021-01-0137

OAAI

Adduct of the blistering warfare agent sesquimustard with human serum albumin and its mass spectrometric identification for biomedical verification of exposure

ANALYTICAL AND BIOANALYTICAL CHEMISTRY

IF3.8

2020-09-0925

OAAI

A case report of cholinesterase inhibitor poisoning: cholinesterase activities and analytical methods for diagnosis and clinical decision making

ARCHIVES OF TOXICOLOGY

IF6.9

2020-04-1714

OAAI

Sulfur mustard alkylates steroid hormones and impacts hormone function in vitro

ARCHIVES OF TOXICOLOGY

IF6.9

2019-09-127

PREAI

Efficacy of an organophosphorus hydrolase enzyme (OpdA) in human serum and minipig models of organophosphorus insecticide poisoning

有机磷水解酶 (OpdA) 在有机磷杀虫剂中毒的人血清和小型猪模型中的功效

CLINICAL TOXICOLOGY

IF3.3

2019-08-2714

OAAI

Forensic evidence of sulfur mustard exposure in real cases of human poisoning by detection of diverse albumin-derived protein adducts

ARCHIVES OF TOXICOLOGY

IF6.9

2019-05-0837

PREAI

Harald John

个人简介

教育背景

工作经历

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