Francesca Cicchetti - Publications, H-index & Citations

Francesca Cicchetti

axe neurosciences

53H指数

182论文数

8.5K被引数

收录论文 95

发表时间

Huntington’s disease vasculopathy is barrier-type-selective and arteriolar-dominant with spatially-coupled astrogliosis and reversible by S1pr1 stimulation 亨廷顿病血管病变具有屏障类型选择性、小动脉主导性，并伴有空间偶联的星形胶质细胞增生，可通过S1pr1刺激逆转

Nature Communications

IF15.7

2026-09-12

OAAI

Krzysztof Kucharz; Rana Soylu-Kucharz; Martine Saint-Pierre; Melanie Alpaugh; Filippa Liliendahl Qvist; Maria Björkqvist; Niels Henning Skotte; Francesca Cicchetti; Martin Johannes Lauritzen

The impact of tau deletion on Huntington’s disease: an in vivo perspective tau基因缺失对亨廷顿病的影响：体内研究视角

Molecular Therapy

IF12

2025-11-28

OAAI

Eva Lepinay; Martine Saint-Pierre; Maxime Teixeira; Marta Snapyan; Abid Oueslati; Martin Parent; Melanie Alpaugh; Francesca Cicchetti

Erythrocyte-derived extracellular vesicles transcytose across the blood-brain barrier to induce Parkinson's disease-like neurodegeneration 红细胞来源的细胞外囊泡通过转胞吞作用穿过血脑屏障，以诱导帕金森病样神经退行性变。

FLUIDS AND BARRIERS OF THE CNS

IF6.2

2025-04-14

OAAI

Denis, Helena L.; Jacquet, Aurelie de Rus; Alpaugh, Melanie; Panisset, Michel; Barker, Roger A.; Boilard, Eric; Cicchetti, Francesca

Ultrasound muscular thickness-based model to identify sarcopenia in patients with portal hypertension (PH): a crosssectional single-center observational study

DIGESTIVE AND LIVER DISEASE

IF3.8

2025-02-01

PREAI

Luca, M.; Tosetti, G.; Cardone, V.; Argiento, L.; Ridolfo, S.; Acquati, E.; Cicchetti, F.; Xhepa, E.; Pavan, M.; Biondetti, P.; Angileri, A.; Stella, S.; Carrafiello, G.; Lampertico, P.

Treatment with Tau fibrils impact Huntington's disease-related phenotypes in cell and mouse models

NEUROBIOLOGY OF DISEASE

IF5.6

2024-11-01

OAAI

Salem, Shireen; Alpaugh, Melanie; Saint-Pierre, Martine; Alves-Martins-Borba, Flavia Natale; Cerquera-Cleves, Catalina; Lemieux, Mado; Ngonza-Nito, Soki Bradel; De Koninck, Paul; Melki, Ronald; Cicchetti, Francesca

Evidence of mutant huntingtin and tau-related pathology within neuronal grafts in Huntington's disease cases

NEUROBIOLOGY OF DISEASE

IF5.6

2024-08-01

OAAI

Salem, Shireen; Kilgore, Mitchell D.; Anwer, Mehwish; Maxan, Alexander; Child, Dan; Bird, Thomas D.; Keene, C. Dirk; Cicchetti, Francesca; Latimer, Caitlin

Reducing huntingtin by immunotherapy delays disease progression in a mouse model of Huntington disease (vol 190, 106376, 2024)通过免疫疗法减少亨廷顿蛋白可延迟亨廷顿病小鼠模型的疾病进展 (190卷，106376，2024)

NEUROBIOLOGY OF DISEASE

IF5.6

2024-04-01

OAAI

Bartl, Stefan; Xie, Yuanyun; Potluri, Nalini; Kesineni, Ratnesh; Hencak, Katlin; Dal Cengio, Louisa; Balazs, Katja; Oueslati, Abid; Parth, Michela; Salhat, Nina; Siddu, Alberto; Smrzka, Oskar; Cicchetti, Francesca; Staffler, Guenther; Hayden, Michael R.; Southwell, Amber L.

Additive neurorestorative effects of exercise and docosahexaenoic acid intake in a mouse model of Parkinson's disease

NEURAL REGENERATION RESEARCH

IF6.7

2024-03-01

OAAI

Kerdiles, Olivier; Mi-mba, Meryl-Farelle Oye Mintsa; Coulombe, Katherine; Tremblay, Cyntia; Emond, Vincent; St-Pierre, Martine; Rouxel, Clemence; Berthiaume, Line; Julien, Pierre; Cicchetti, Francesca; Calon, Frederic

Reducing huntingtin by immunotherapy delays disease progression in a mouse model of Huntington disease 通过免疫疗法减少亨廷顿蛋白可延缓亨廷顿病小鼠模型的疾病进展

NEUROBIOLOGY OF DISEASE

IF5.6

2024-01-01

OAAI

Bartl, Stefan; Xie, Yuanyun; Potluri, Nalini; Kesineni, Ratnesh; Hencak, Katlin; Dal Cengio, Louisa; Balazs, Katja; Oueslati, Abid; Parth, Michela; Salhat, Nina; Siddu, Alberto; Smrzka, Oskar; Cicchetti, Francesca; Hayden, Michael R.; Southwell, Amber L.; Straffler, Guenther

Tau: a biomarker of Huntington's disease

MOLECULAR PSYCHIATRY

IF10.1

2023-09-25

PREAI

Lepinay, Eva; Cicchetti, Francesca

The contribution of inflammatory astrocytes to BBB impairments in a brain-chip model of Parkinson's disease

NATURE COMMUNICATIONS

IF15.7

2023-06-20

OAAI

de Rus Jacquet, A.; Alpaugh, M.; Denis, H. L.; Tancredi, J. L.; Boutin, M.; Decaestecker, J.; Beauparlant, C.; Herrmann, L.; Saint-Pierre, M.; Parent, M.; Droit, A.; Breton, S.; Cicchetti, F.

Understanding the role of the hematopoietic niche in Huntington?s disease?s phenotypic expression: in vivo evidence using a parabiosis model

NEUROBIOLOGY OF DISEASE

IF5.6

2023-05-01

OAAI

Rieux, Marie; Alpaugh, Melanie; Salem, Shireen; Siddu, Alberto; Saint-Pierre, Martine; Denis, Helena L.; Rohweder, Heike; Herrmann, Frank; Bazenet, Chantal; Lacroix, Steve; Cicchetti, Francesca

Detection of antibodies against the huntingtin protein in human plasma 人血浆中亨廷顿蛋白抗体的检测

CELLULAR AND MOLECULAR LIFE SCIENCES

IF6.2

2023-01-18

OAAI

Denis, Helena L.; Alpaugh, Melanie; Alvarez, Claudia P. P.; Fenyi, Alexis; Barker, Roger A. A.; Chouinard, Sylvain; Arrowsmith, Cheryl H. H.; Melki, Ronald; Labib, Richard; Harding, Rachel J. J.; Cicchetti, Francesca

Prompting endogenous repair of brain injury: science fiction or reality?

MOLECULAR NEURODEGENERATION

IF17.5

2022-05-31

OAAI

de Rus Jacquet, Aurelie; Cicchetti, Francesca

Passive immunization against phosphorylated tau improves features of Huntington's disease pathology

MOLECULAR THERAPY

IF12

2022-04-01

OAAI

Alpaugh, Melanie; Masnata, Maria; Jacquet, Aurelie de Rus; Lepinay, Eva; Denis, Helena L.; Saint-Pierre, Martine; Davies, Peter; Planel, Emmanuel; Cicchetti, Francesca

Sox6 expression distinguishes dorsally and ventrally biased dopamine neurons in the substantia nigra with distinctive properties and embryonic origins

CELL REPORTS

IF6.9

2021-11-01

OAAI

Luppi, Milagros Pereira; Azcorra, Maite; Caronia-Brown, Giuliana; Poulin, Jean-Francois; Gaertner, Zachary; Gatica, Serafin; Moreno-Ramos, Oscar Andres; Nouri, Navid; Dubois, Marilyn; Ma, Yongchao C.; Ramakrishnan, Charu; Fenno, Lief; Kim, Yoon Seok; Deisseroth, Karl; Cicchetti, Francesca; Dombeck, Daniel A.; Awatramani, Rajeshwar

DNMT3A and DNMT3B Targeting as an Effective Radiosensitizing Strategy in Embryonal Rhabdomyosarcoma

CELLS

IF5.2

2021-10-30

OAAI

Camero, Simona; Vitali, Giulia; Pontecorvi, Paola; Ceccarelli, Simona; Anastasiadou, Eleni; Cicchetti, Francesca; Flex, Elisabetta; Pomella, Silvia; Cassandri, Matteo; Rota, Rossella; Marampon, Francesco; Marchese, Cinzia; Schiavetti, Amalia; Megiorni, Francesca

Prion-like properties of the mutant huntingtin protein in living organisms: the evidence and the relevance

MOLECULAR PSYCHIATRY

IF10.1

2021-10-28

PREAI

Alpaugh, Melanie; Denis, Helena L.; Cicchetti, Francesca

Clinical perception and management of Parkinson's disease during the COVID-19 pandemic: A Canadian experience

PARKINSONISM & RELATED DISORDERS

IF3.4

2021-10-01

OAAI

Jacquet, Aurelie de Rus; Bogard, Sarah; Normandeau, Catherine P.; Degroot, Clotilde; Postuma, Ronald B.; Dupre, Nicolas; Miyasaki, Janis M.; Monchi, Oury; Martino, Davide; Fon, Edward A.; Cicchetti, Francesca

IN VIVO MTHTT PROTEIN REDUCTION IN THE CNS AND PERIPHERY BY PASSIVE IMMUNIZATION WITH THE MONOCLONAL ANTIBODY C6-17

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

IF7.5

2021-09-05

PREAI

Bartl, Stefan; Xie, Yuanyun; Potluri, Nalini; Gordon, Benjamin; Willenberg, Alicia; Balash, Katja; Oueslati, Abid; Parth, Michela; Salhat, Nina; Siddu, Alberto; Smrzka, Oskar; Cicchetti, Francesca; Straffler, Gunther; Hayden, Michael R.; Southwell, Amber L.

研究方向