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A

Alan K. Hunter

Pfizer

25H指数
61论文数
1.7K被引数
收录论文 38
发表时间
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Leveraging light chain binding avidity for control of mispaired byproducts during production of asymmetric bispecific antibodies
errJOURNAL OF CHROMATOGRAPHY A
IF4
err2022-11-01
err6
errOAAI
errRezvani, Kamiyar; WuDunn, Dominique; Hunter, Alan K.; Aspelund, Matthew T.
err分享
err收藏
Formation of transient highly-charged mAb clusters strengthens interactions with host cell proteins and results in poor clearance of host cell proteins by protein A chromatography
errJOURNAL OF CHROMATOGRAPHY A
IF4
err2022-08-01
err14
PREAI
errLuo, Haibin; Du, Qun; Qian, Chen; Mlynarczyk, Michelle; Pabst, Timothy M.; Damschroder, Melissa; Hunter, Alan K.; Wang, William K.
err分享
err收藏
Identification of a CE-SDS shoulder peak as disulfide-linked fragments from common CH2 cleavages in IgGs and IgG-like bispecific antibodies
errMABS
IF7.3
err2021-11-01
err7
errOAAI
errCao, Mingyan; Jiao, Yang; Parthemore, Conner; Korman, Samuel; Ma, Jiao; Hunter, Alan; Kilby, Greg; Chen, Xiaoyu
err分享
err收藏
Challenges for design of aggregation-resistant variants of granulocyte colony-stimulating factor粒细胞集落刺激因子抗聚集变异体设计的挑战
errBIOPHYSICAL CHEMISTRY
IF2.2
err2021-10-01
err2
errOAAI
errMeric, Gulsum; Naik, Subhashchandra; Hunter, Alan K.; Robinson, Anne S.; Roberts, Christopher J.
err分享
err收藏
Role of configurational flexibility on the adsorption kinetics of bivalent bispecific antibodies on porous cation exchange resins
errJOURNAL OF CHROMATOGRAPHY A
IF4
err2021-10-01
err5
PREAI
errKimerer, Lucas K.; Pabst, Timothy M.; Hunter, Alan K.; Carta, Giorgio
err分享
err收藏
Characterization and Monitoring of a Novel Light-heavy-light Chain Mispair in a Therapeutic Bispecific Antibody
errJOURNAL OF PHARMACEUTICAL SCIENCES
IF3.8
err2021-08-01
err15
errOAAI
errCao, Mingyan; Parthemore, Conner; Jiao, Yang; Korman, Samuel; Aspelund, Matthew; Hunter, Alan; Kilby, Greg; Chen, Xiaoyu
err分享
err收藏
Chromatographic and adsorptive behavior of a bivalent bispecific antibody and associated fragments
errJOURNAL OF CHROMATOGRAPHY A
IF4
err2021-07-01
err7
PREAI
errKimerer, Lucas K.; Niu, Ben; Pabst, Timothy M.; Zhai, Weiguo; Hunter, Alan K.; Carta, Giorgio
err分享
err收藏
Development of a mechanism of action-reflective, dual target cell-based reporter bioassay for a bispecific monoclonal antibody targeting human CTLA-4 and PD-1
errMABS
IF7.3
err2021-04-18
err6
errOAAI
errChen, Weimin; Pandey, Madhu; Sun, Hong; Rolong, Andrea; Cao, Mingyan; Liu, Dengfeng; Wang, Jihong; Zeng, Lingmin; Hunter, Alan; Lin, Shihua
err分享
err收藏
Chromatographic behavior of bivalent bispecific antibodies on hydrophobic interaction chromatography columns
errJOURNAL OF CHROMATOGRAPHY A
IF4
err2020-04-01
err11
errOAAI
errKimerer, Lucas K.; Pabst, Timothy M.; Hunter, Alan K.; Carta, Giorgio
err分享
err收藏
Chromatographic behavior of bivalent bispecific antibodies on cation exchange columns. I. Experimental observations and phenomenological model
errJOURNAL OF CHROMATOGRAPHY A
IF4
err2019-09-01
err20
PREAI
errKimerer, Lucas K.; Pabst, Timothy M.; Hunter, Alan K.; Carta, Giorgio
err分享
err收藏
Chromatographic behavior of bivalent bispecific antibodies on cation exchange columns. II. Biomolecular perspectives
errJOURNAL OF CHROMATOGRAPHY A
IF4
err2019-09-01
err12
PREAI
errKimerer, Lucas K.; Pabst, Timothy M.; Hunter, Alan K.; Carta, Giorgio
err分享
err收藏
Process optimization and protein engineering mitigated manufacturing challenges of a monoclonal antibody with liquid-liquid phase separation issue by disrupting inter-molecule electrostatic interactions
errMABS
IF7.3
err2019-04-14
err13
errOAAI
errDu, Qun; Damschroder, Melissa; Pabst, Timothy M.; Hunter, Alan K.; Wang, William K.; Luo, Haibin
err分享
err收藏
Characterization and analysis of scFv-IgG bispecific antibody size variantsScfv-igg双特异性抗体大小变体的表征和分析
errMABS
IF7.3
err2018-09-20
err29
errOAAI
errCao, Mingyan; Wang, Chunlei; Chung, Wai Keen; Motabar, Dana; Wang, Jihong; Christian, Elizabeth; Lin, Shihua; Hunter, Alan; Wang, Xiangyang; Liu, Dengfeng
err分享
err收藏
A systematic approach for analysis and characterization of mispairing in bispecific antibodies with asymmetric architecture
errMABS
IF7.3
err2018-09-20
err50
errOAAI
errWang, Chunlei; Vemulapalli, Bhargavi; Cao, Mingyan; Gadre, Dhanesh; Wang, Jihong; Hunter, Alan; Wang, Xiangyang; Liu, Dengfeng
err分享
err收藏
Systematic Interpolation Method Predicts Antibody Monomer-Dimer Separation by Gradient Elution Chromatography at High Protein Loads
errBIOTECHNOLOGY JOURNAL
IF3.1
err2018-06-11
err20
PREAI
errCreasy, Arch; Reck, Jason; Pabst, Timothy; Hunter, Alan; Barker, Gregory; Carta, Giorgio
err分享
err收藏
Evaluation of recent Protein A stationary phase innovations for capture of biotherapeutics
errJOURNAL OF CHROMATOGRAPHY A
IF4
err2018-06-01
err93
errOAAI
errPabst, Timothy M.; Thai, Johnny; Hunter, Alan K.
err分享
err收藏
Separation of antibody monomer-dimer mixtures by frontal analysis通过前沿分析分离抗体单体-二聚体混合物
errJOURNAL OF CHROMATOGRAPHY A
IF4
err2017-06-01
err35
PREAI
errReck, Jason M.; Pabst, Timothy M.; Hunter, Alan K.; Carta, Giorgio
err分享
err收藏
Liquid-liquid phase separation causes high turbidity and pressure during low pH elution process in Protein A chromatography
errJOURNAL OF CHROMATOGRAPHY A
IF4
err2017-03-01
err18
errOAAI
errLuo, Haibin; Lee, Nacole; Wang, Xiangyang; Li, Yuling; Schmelzer, Albert; Hunter, Alan K.; Pabst, Timothy; Wang, William K.
err分享
err收藏
Camelid VHH affinity ligands enable separation of closely related biopharmaceuticals
errBIOTECHNOLOGY JOURNAL
IF3.1
err2016-10-20
err19
errOAAI
errPabst, Timothy M.; Wendeler, Michaela; Wang, Xiangyang; Bezemer, Sandra; Hermans, Pim; Hunter, Alan K.
err分享
err收藏
Adsorption equilibrium and kinetics of monomer-dimer monoclonal antibody mixtures on a cation exchange resin
errJOURNAL OF CHROMATOGRAPHY A
IF4
err2015-07-01
err34
PREAI
errReck, Jason M.; Pabst, Timothy M.; Hunter, Alan K.; Wang, Xiangyang; Carta, Giorgio
err分享
err收藏

研究方向

暂时未获取到该数据
合作学者
合作期刊
J
Joseph K. McLaughlin
H 指数: 88 · 论文数: 466
C
Christopher J. Roberts
H 指数: 60 · 论文数: 193
X
Xiangyang Wang
H 指数: 59 · 论文数: 439
汪
汪洋 (Yang Wang)
H 指数: 52 · 论文数: 647
G
Giorgio Carta
H 指数: 49 · 论文数: 246
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