James W. Freeman - Publications, H-index & Citations

James W. Freeman

university of texas system

37H指数

140论文数

4.5K被引数

收录论文 30

发表时间

Gemcitabine resistance of pancreatic cancer cells is mediated by IGF1R dependent upregulation of CD44 expression and isoform switching

CELL DEATH & DISEASE

IF9.6

2022-08-05

OAAI

Chen, Chen; Zhao, Shujie; Zhao, Xiangru; Cao, Lin; Karnad, Anand; Kumar, Addanki P.; Freeman, James W.

The biology and role of CD44 in cancer progression: therapeutic implications CD44在癌症进展中的生物学和作用: 治疗意义

JOURNAL OF HEMATOLOGY & ONCOLOGY

IF40.4

2018-05-10

900

OAAI

Chen, Chen; Zhao, Shujie; Karnad, Anand; Freeman, James W.

Role of CD44 as a regulator of adaptive plasticity in pancreatic cancer cells

CANCER RESEARCH

IF16.6

2017-07-01

PREAI

Chen, Chen; Zhao, Shujie; Zhao, Xiangru; Freeman, James W.

Role of CD44 in pancreatic cancer cell plasticity

CANCER RESEARCH

IF16.6

2016-12-14

PREAI

Freeman, James W.; Zhao, Shujie; Chen, Chen; Karnad, Anand

Elucidating the mechanism of the STAT3/NF-κB/EP4 signaling axis in pancreatic cancer

CANCER RESEARCH

IF16.6

2016-07-15

PREAI

Munoz, Amanda R.; Freeman, James W.; Kumar, Addanki P.

Downregulation of STAT3/NF-B potentiates gemcitabine activity in pancreatic cancer cells

MOLECULAR CARCINOGENESIS

IF3.2

2016-05-25

OAAI

Gong, Jingjing; Munoz, Amanda R.; Pingali, Subramanya; Payton-Stewart, Florastina; Chan, Daniel E.; Freeman, James W.; Ghosh, Rita; Kumar, Addanki P.

A microRNA signature identified for chemoresistance and mesenchymal phenotype is also found in advanced pancreatic cancer

CANCER RESEARCH

IF16.6

2015-06-30

PREAI

Freeman, James W.; Bera, Alakesh; Kolaparthi, Venkatasubbarao

Epigenetic modulation and attacking the hedgehog pathway Potentially synergistic therapeutic targets for pancreatic cancer 表观遗传调控和攻击hedgehog通路可能是胰腺癌的协同治疗靶点

CANCER BIOLOGY & THERAPY

IF4.6

2014-10-27

OAAI

Freeman, James W.; Wang, Yubao; Giles, Francis J.

Knockdown of RON receptor kinase delays but does not prevent tumor progression while enhancing HGF/MET signaling in pancreatic cancer cell lines

ONCOGENESIS

IF6.4

2013-10-07

OAAI

Zhao, S.; Cao, L.; Freeman, J. W.

Inhibiting signal transducer and activator of transcription-3 increases response to gemcitabine and delays progression of pancreatic cancer

MOLECULAR CANCER

IF33.9

2013-09-11

OAAI

Venkatasubbarao, Kolaparthi; Peterson, Lindsay; Zhao, Shujie; Hill, Ping; Cao, Lin; Zhou, Qing; Nawrocki, Steffan T.; Freeman, James W.

Reolysin is a novel reovirus-based agent that induces endoplasmic reticular stress-mediated apoptosis in pancreatic cancer

CELL DEATH & DISEASE

IF9.6

2013-07-18

OAAI

Carew, J. S.; Espitia, C. M.; Zhao, W.; Kelly, K. R.; Coffey, M.; Freeman, J. W.; Nawrocki, S. T.

Reovirus Therapy Induces Endoplasmic Reticular Stress and Apoptosis in RAS-activated Pancreatic Cancer

EUROPEAN JOURNAL OF CANCER

IF7.1

2012-11-01

PREAI

Carew, J. S.; Espitia, C. M.; Kelly, K. R.; Coffey, M.; Freeman, J. W.; Nawrocki, S. T.

Reolysin: A novel reovirus-based agent that induces endoplasmic reticular stress in RAS-activated pancreatic cancer

CANCER RESEARCH

IF16.6

2012-04-01

PREAI

Carew, Jennifer S.; Espitia, Claudia M.; Kelly, Kevin R.; Coffey, Matt; Freeman, James W.; Nawrocki, Steffan T.

Gemcitabine resistance is associated with EMT phenotype along with expression of cancer stem cell markers and a specific miRNA profile in the human pancreatic cancer cell line BxPC3

CANCER RESEARCH

IF16.6

2012-04-01

PREAI

Bera, Alakesh; Freeman, James W.; VenkataSubbaRao, Kolaparthi; Zhao, Shujie

Novel Function of Transcription Factor Nrf2 as an Inhibitor of RON Tyrosine Kinase Receptor-mediated Cancer Cell Invasion

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2011-09-01

OAAI

Thangasamy, Amalraj; Rogge, Jessica; Krishnegowda, Naveen K.; Freeman, James W.; Ammanamanchi, Sudhakar

Expression of oncogenic K-ras and loss of Smad4 cooperate to induce the expression of EGFR and to promote invasion of immortalized human pancreas ductal cells

INTERNATIONAL JOURNAL OF CANCER

IF4.7

2010-08-26

OAAI

Zhao, Shujie; Wang, Yubao; Cao, Lin; Ouellette, Michel M.; Freeman, James W.

Inhibition of STAT3Tyr705 phosphorylation by Smad4 suppresses transforming growth factor β-mediated invasion and metastasis in pancreatic cancer cells

CANCER RESEARCH

IF16.6

2008-06-02

126

OAAI

Zhao, Shujie; Venkatasubbarao, Kolaparthi; Lazor, Jillian W.; Sperry, Jane; Jin, Changqing; Cao, Lin; Freeman, James W.

Smad4-dependent TGF-β signaling suppresses RON receptor tyrosine kinase-dependent motility and invasion of pancreatic cancer cells

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2008-04-01

OAAI

Zhao, Shujie; Ammanamanchi, Sudhakar; Brattain, Michael; Cao, Lin; Thangasamy, Amalraj; Wang, Jing; Freeman, James W.

Farnesyl transferase inhibitor (R115777)-induced inhibition of STAT3(Tyr705) phosphorylation in human pancreatic cancer cell lines require extracellular signal-regulated kinases

CANCER RESEARCH

IF16.6

2005-04-01

PREAI

Venkatasubbarao, K; Choudary, A; Freeman, JW

Trichostatin a induces transforming growth factor ß type II receptor promoter activity and acetylation of Sp1 by recruitment of PCAF/p300 to a Sp1•NF-Y complex

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2005-03-01

127

OAAI

Huang, WQ; Zhao, SJ; Ammanamanchi, S; Brattain, M; Venkatasubbarao, K; Freeman, JW

研究方向