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Characterizing safety, toxicity, and breast cancer risk reduction using a long-term fulvestrant eluting implant Thomas, Scott; Roche, Elysia; Desai, Pujan; Pawlowska, Nela; Bauer, Diana; Gingrich, David; Hsu, Emily; Deitchman, Amelia N.; Aweeka, Fran; Munster, Pamela N. 分享 收藏
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Updated results from VERITAC evaluating vepdegestrant, a PROteolysis TArgeting Chimera (PROTAC) estrogen receptor (ER) degrader, in ER- positive/human epidermal growth factor receptor 2 (HER2)-negative advanced breast cancer VERITAC评估ER阳性/人表皮生长因子受体2 (HER2) 阴性晚期乳腺癌中蛋白水解靶向嵌合体 (PROTAC) 雌激素受体 (ER) 降解剂vepdegestrant的更新结果 Hurvitz, Sara; Schott, Anne; Ma, Cynthia; Nanda, Rita; Zahrah, George; Hunter, Natasha; Tan, Antoinette; Telli, Melinda; Mesias, Jesus Anampa; Jeselsohn, Rinath; Munster, Pamela; Zhi, Eric; Duperret, Elizabeth; Mather, Cecile; Hamilton, Erika; Han, Hyo 分享 收藏
Report on Cohort Expansion of Phase I Study to Investigate the Safety, Tolerability, Pharmacokinetics and Antitumor Activity of BB-1701 in Patients with Locally Advanced/Metastatic HER2 Low Breast Cancer Ma, Fei; Munster, Pamela; Guan, Xiaoxiang; Wang, Jingfen; Yao, Herui; Hamilton, Erika; Wang, Xian; Shi, Yehui; Liang, Xinjun; Xu, Nong; Tang, Huoling; Zhou, Yuhong; Wei, Ziping 分享 收藏
A phase 1/2, first-in-human study of STX-478 monotherapy or in combination with fulvestrant in patients with breast cancer or other advanced solid tumors (trial in progress) Montero, Alberto; Orr, Douglas; Munster, Pamela; LoRusso, Patricia; Jhaveri, Komal; Pluard, Timothy; Winer, Ira; Streit, Michael; Patterson, Monica; Roberts, Simon; Corsi-Travali, Stefani; Ewert, Courtney; Juric, Dejan 分享 收藏
A PHASE 1 SAFETY, PK AND PRELIMINARY EFFICACY STUDY OF LOCALIZED THERAPY USING BIOLEN (BICALUTAMIDE) IMPLANTS FOR EARLY-STAGE PROSTATE CANCER Kenigsberg, Alexander; Woo, Henry; Fraundorfer, Mark; Brennan, Janelle; Chin, Peter; Citrin, Deborah; Turkbey, Baris; Choyke, Peter; Wood, Bradford; Gurram, Sandeep; Desai, Pujan; Rairkar, Maithili; Munster, Pamela; Pinto, Peter 分享 收藏
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First-in-human Evaluation of a Prostate-specific Membrane Antigen-targeted Near-infrared Fluorescent Small Molecule for Fluorescence-based Identification of Prostate Cancer in Patients with High-risk Prostate Cancer Undergoing Robotic-assisted Prostatectomy Nguyen, Hao G.; van den Berg, Nynke S.; Antaris, Alexander L.; Xue, Lingru; Greenberg, Scott; Rosenthal, J. Walker; Muchnik, Anna; Klaassen, Alwin; Simko, Jeffry P.; Dutta, Sanjeev; Sorger, Jonathan M.; Munster, Pamela; Carroll, Peter R. 分享 收藏
Phase 1 dose expansion results of CYT-0851, a monocarboxylate transporter (MCT) inhibitor, in combination with capecitabine (cape) in platinum-resistant ovarian cancer Swisher, Elizabeth; Falchook, Gerald Steven; Munster, Pamela N.; Bed, Nina; Moore, Kathleen N.; Yap, Timothy A.; Spigel, David R.; Doleman, Susan; Bradley, William D.; O'Shea, Thomas J.; Renschler, Markus F.; Lynch, Ryan C. 分享 收藏
First-in-human phase 1/1b trial of the first-in-class bi-steric mTORC1-selective inhibitor RMC-5552 in patients with advanced solid tumors Schram, Alison M.; Nagash, Abdul Rafeh; Haura, Eric B.; Riess, Jonathan W.; Ulahannan, Susanna V.; Ou, Sai-Hong I.; Capasso, Anna; Munster, Pamela N.; Cheng, Michael L.; Gustafson, W. Clay; Bitman, Bojena; Kar, Sumit; Wang, Zhican; Tao, Lin; Meyerowitz, Justin G.; Burns, Howard A. 分享 收藏
A Phase 1b/2 Study of Alpelisib in Combination with Cetuximab in Patients with Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma Alpelisib联合西妥昔单抗治疗复发或转移性头颈部鳞状细胞癌的1b/2期研究 Razak, Albiruni R. Abdul; Wang, Hung-Ming; Chang, Jang-Yang; Ahn, Myung-Ju; Munster, Pamela; Blumenschein Jr, George; Solomon, Benjamin; Lim, Darren Wan-Teck; Hong, Ruey-Long; Pfister, David; Saba, Nabil F.; Lee, Se-Hoon; van Herpen, Carla; Quadt, Cornelia; Bootle, Douglas; Blumenstein, Lars; Demanse, David; Delord, Jean-Pierre 分享 收藏
Safety and efficacy of D-1553 in combination with cetuximab in KRAS G12C mutated colorectal cancer (CRC): A phase II study Xu, R-H.; Xu, Y.; Yan, D.; Munster, P.; Ruan, D.; Deng, Y.; Pan, H.; Underhill, C. R.; Richardson, G.; Nordman, I.; Lee, K-W.; Wei, S.; Li, X.; Shan, J.; Han, G.; Henderson, S.; Xie, X.; Xiang, Z.; Shi, Z.; Zhang, L. 分享 收藏
Vepdegestrant, a proteolysis targeting chimera (PROTAC) estrogen receptor (ER) degrader, in ER plus /human epidermal growth factor receptor 2 (HER2)- advanced breast cancer: Update of dose escalation results from a phase I/II trial Hamilton, E. P.; Han, H.; Schott, A.; Tan, A.; Nanda, R.; Juric, D.; Hunter, N.; Munster, P.; Fang, B.; Zahrah, G.; Ranciato, J.; Gedrich, R.; Zhi, E.; Zhang, Y.; Tan, W.; Mather, C.; Perkins, J.; Anderson, S.; Hurvitz, S. A. 分享 收藏
Pembrolizumab alone and pembrolizumab plus chemotherapy in previously treated, extrapulmonary poorly differentiated neuroendocrine carcinomas Raj, Nitya; Chan, Jennifer A.; Wang, Stephanie J.; Aggarwal, Rahul R.; Calabrese, Susan; DeMore, April; Fong, Lawrence; Grabowsky, Jennifer; Hope, Thomas A.; Kolli, Kanti Pallav; Mulvey, Claire K.; Munster, Pamela N.; Perez, Kimberly; Punn, Sippy; Reidy-Lagunes, Diane; Von Fedak, Sofia; Zhang, Li; Bergsland, Emily K. 分享 收藏
Multimodal mechanism of action of the GSK-3 inhibitor 9-ING-41 (elraglusib) includes an immunomodulatory component: preliminary results from the 1801 phase 1/2 trial Weiskittel, Taylor; McDermott, Joseph; Billadeau, Daniel; Li, Hu; Saeed, Anwaar; Mahalingam, Devalingam; Sahebjam, Solmaz; Munster, Pamela; Cavalcante, Ludimila; Giles, Frank J.; Mazar, Andrew; Carneiro, Benedito 分享 收藏
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