Marius C. Hoener - Publications, H-index & Citations

Marius C. Hoener

roche innovation center basel

51H指数

136论文数

9.0K被引数

收录论文 74

发表时间

403. Sustained administration of the full and partial agonists of trace amine associated receptor 1 (TAAR1) induces different effects on the excitability of central monoaminergic neurons 403. TAAR1（痕量胺相关受体1）的全激动剂和部分激动剂的持续给药对中枢单胺能神经元兴奋性的诱导作用不同

International Journal of Neuropsychopharmacology

IF3.7

2026-09-09

OAAI

T Khoury; D Grinchii; M C Hoener; E Dremencov

Novel selective morpholine trace amine-associated receptor 1 partial agonists show promising preclinical effects for neuropsychiatric disorders and are well tolerated in healthy volunteers 新型选择性吗啉基痕量胺相关受体1部分激动剂在神经精神疾病方面显示出有前景的预临床效果，并且在健康受试者中耐受性良好。

Molecular Psychiatry

IF10.1

2026-02-04

PREAI

Céline Fournier; Danièle Buchy; Susanne Mohr; Axel Pähler; Bjoern Jacobsen; Roger Norcross; Philippe Pflieger; Sabine Sewing; Andrea Greiter-Wilke; Basil Kuennecke; Christophe Schmitt; Mary Morrison; Maddalena Marchesi; Stefan Holiga; Irene Gerlach; Marius C. Hoener

Receptor interaction profiles of 4-alkoxy-2; 6-dimethoxyphenethylamines (Ψ derivatives) and related amphetamines 4-烷氧基-2,6-二甲氧基苯乙胺（Ψ衍生物）及相关苯丙胺的受体相互作用谱

Frontiers in Pharmacology

IF4.8

2025-11-20

OAAI

Karolina E. Kolaczynska; Daniel Trachsel; Marius C. Hoener; Matthias E. Liechti; Dino Luethi

Preclinical development of [18F]TAAR1-2203 as a PET radioligand for imaging TAAR1 expression and receptor occupancy [18F]TAAR1-2203作为PET放射性配体，用于成像TAAR1表达和受体占位的临床前开发

European Journal of Nuclear Medicine and Molecular Imaging

IF7.6

2025-11-06

OAAI

Achi Haider; Zhiwei Xiao; Jiahui Chen; Stefanie K. Pfister; Xin Zhou; Yinlong Li; Ahmad Chaudhary; Chunyu Zhao; Jian Rong; Axel Paehler; Susanne Mohr; Roger D. Norcross; Michael Honer; Linjing Mu; Luca Gobbi; Roger Schibli; Marius C. Hoener; Steven H. Liang

The 4-alkyl chain length of 2,5-dimethoxyamphetamines differentially affects in vitro serotonin receptor actions versus in vivo psychedelic-like effects 2,5-二甲基苯丙胺的4-位烷基链长度差异性地影响体外5-羟色胺受体作用与体内迷幻样效应。

Molecular Psychiatry

IF10.1

2025-11-05

OAAI

Dino Luethi; Grant C. Glatfelter; Eline Pottie; Francesca Sellitti; Alexander D. Maitland; Nicholas R. Gonzalez; Lindsay A. Kryszak; Shelley N. Jackson; Marius C. Hoener; Christophe P. Stove; Matthias E. Liechti; Martin Smieško; Michael H. Baumann; Linda D. Simmler; Deborah Rudin

Angelman syndrome patient-derived neuron screen leads to clinical ASO rugonersen targeting UBE3A-ATS with long-lasting effect in monkeys Angelman综合征患者源性神经元筛选导致靶向UBE3A-ATS且具有长效作用的临床ASO药物ronersen在猴子中取得进展

Nucleic Acids Research

IF13.1

2025-08-30

OAAI

Ravi Jagasia; Charlotte Bon; Soren V Rasmussen; Solveig Badillo; Disa Tehler; Danièle Buchy; Marco Berrera; Megana Prasad; Stormy Chamberlain; Marco Terrigno; Nikhil J Pandya; Veronica Costa; Congwei Wang; Lykke Pedersen; Meghan T Miller; Kamille Dumong Erichsen; Lars Joenson; Christoph Patsch; Joerg F Hipp; Azad Bonni; Lutz Müller; Annamaria Braendli-Baiocco; Thomas Kremer; Erich Koller; Marius C Hoener

LIGANDS OF THE DELTA-OPIOID RECEPTOR AND TRACE AMINE ASSOCIATED RECEPTOR 1 EXERT SIMILAR EFFECTS ON MONOAMINERGIC TRANSMISSION IN RATS δ-阿片受体和单胺相关受体1的配体对大鼠的单胺能传递产生相似的作用

INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

IF3.7

2025-02-12

OAAI

Grinchii, Daniil; Khoury, Talah; Hoener, Marius C.; Jezova, Daniela; Dremencov, Eliyahu

Trace amine-associated receptors (TAARs)2-9 knockout mice exhibit reduced wakefulness and disrupted REM sleep

FRONTIERS IN PSYCHIATRY

IF3.2

2025-01-29

OAAI

Park, Sunmee; Heu, Jasmine; Scheldrup, Gavin; Tisdale, Ryan K.; Sun, Yu; Haire, Meghan; Ma, Shun-Chieh; Hoener, Marius C.; Kilduff, Thomas S.

Trace amine-associated receptor 1 agonism promotes wakefulness without impairment of cognition in Cynomolgus macaques (vol 44, pg 1485, 2019)

NEUROPSYCHOPHARMACOLOGY

IF7.1

2023-06-07

OAAI

Goonawardena, Anushka V.; Morairty, Stephen R.; Dell, Ryan; Orellana, Gabriel A.; Hoener, Marius C.; Wallace, Tanya L.; Kilduff, Thomas S.

Activation of trace amine-associated receptor 1 (TAAR1) transiently reduces alcohol drinking in socially housed mice 微量胺相关受体1 (TAAR1) 的激活可暂时减少社交小鼠的饮酒

ADDICTION BIOLOGY

IF2.6

2023-05-31

OAAI

Frycz, Bartosz Adam; Nowicka, Klaudia; Konopka, Anna; Hoener, Marius Christian; Bulska, Ewa; Kaczmarek, Leszek; Stefaniuk, Marzena

Translational molecular imaging and drug development in Parkinson's disease

MOLECULAR NEURODEGENERATION

IF17.5

2023-02-10

OAAI

Haider, Ahmed; Elghazawy, Nehal H.; Dawood, Alyaa; Gebhard, Catherine; Wichmann, Thomas; Sippl, Wolfgang; Hoener, Marius; Arenas, Ernest; Liang, Steven H.

Use of the head-twitch response to investigate the structure-activity relationships of 4-thio-substituted 2,5-dimethoxyphenylalkylamines

PSYCHOPHARMACOLOGY

IF3.3

2022-12-07

OAAI

Halberstadt, Adam L.; Luethi, Dino; Hoener, Marius C.; Trachsel, Daniel; Brandt, Simon D.; Liechti, Matthias E.

TAAR1 Regulates Purinergic-induced TNF Secretion from Peripheral, But Not CNS-resident, Macrophages

JOURNAL OF NEUROIMMUNE PHARMACOLOGY

IF3.5

2022-11-16

PREAI

Barnes, David A.; Hoener, Marius C.; Moore, Craig S.; Berry, Mark D.

Effects of acute and chronic administration of trace amine-associated receptor 1 (TAAR1) ligands on in vivo excitability of central monoamine-secreting neurons in rats

MOLECULAR PSYCHIATRY

IF10.1

2022-09-01

OAAI

Grinchii, Daniil; Hoener, Marius C.; Khoury, Talah; Dekhtiarenko, Roman; Bervanlou, Reyhaneh Nejati; Jezova, Daniela; Dremencov, Eliyahu

Pharmacological characterization of 3,4-methylenedioxamphetamine (MDA) analogs and two amphetamine-based compounds: N,α-DEPEA and DPIA

EUROPEAN NEUROPSYCHOPHARMACOLOGY

IF6.7

2022-06-01

OAAI

Kolaczynska, Karolina E.; Ducret, Paula; Trachsel, Daniel; Hoener, Marius C.; Liechti, Matthias E.; Luethi, Dino

Monoamine Receptor and Transporter Interaction Profiles of 4-Alkyl-Substituted 2,5-Dimethoxyamphetamines

FASEB JOURNAL

IF4.2

2022-05-13

PREAI

Luethi, Dino; Rudin, Deborah; Hoener, Marius C.; Liechti, Mattias E.

Structure-activity Relation of Halogenated 2,5-Dimethoxyamphetamines Compared to their α-Desmethyl (2C) Analogues

FASEB JOURNAL

IF4.2

2022-05-13

PREAI

Rudin, Deborah; Luethi, Dino; Hoener, Marius C.; Liechti, Matthias E.

Acute and chronic effects of trace amine-associated receptor one ligands on the excitability of rat serotonin neurons

EUROPEAN NEUROPSYCHOPHARMACOLOGY

IF6.7

2021-12-01

PREAI

Khoury, T.; Grinchii, D.; Hoener, M.; Dremencov, E.

Antisense oligonucleotide treatment rescues UBE3A expression and multiple phenotypes of an Angelman syndrome mouse model

JCI INSIGHT

IF6.1

2021-08-09

OAAI

Milazzo, Claudia; Mientjes, Edwin J.; Wallaard, Ilse; Rasmussen, Soren Vestergaard; Erichsen, Kamille Dumong; Kakunuri, Tejaswini; van der Sman, A. S. Elise; Kremer, Thomas; Miller, Meghan T.; Hoener, Marius C.; Elgersma, Ype

Secreted retrovirus-like GAG-domain-containing protein PEG10 is regulated by UBE3A and is involved in Angelman syndrome pathophysiology

CELL REPORTS MEDICINE

IF10.6

2021-08-01

OAAI

Pandya, Nikhil J.; Wang, Congwei; Costa, Veronica; Lopatta, Paul; Meier, Sonja; Zampeta, F. Isabella; Punt, A. Mattijs; Mientjes, Edwin; Grossen, Philip; Distler, Tania; Tzouros, Manuel; Marti, Yasmina; Banfai, Balazs; Patsch, Christoph; Rasmussen, Soren; Hoener, Marius; Berrera, Marco; Kremer, Thomas; Dunkley, Tom; Ebeling, Martin; Distel, Ben; Elgersma, Ype; Jagasia, Ravi

研究方向