Paul Modrich - Publications, H-index & Citations

Paul Modrich

Duke University

93H指数

208论文数

2.9W被引数

收录论文 74

发表时间

Recognition and repair of compound DNA lesions (base damage and mismatch) by human mismatch repair and excision repair systems

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-29

193

OAAI

Mu, D; Tursun, M; Duckett, DR; Drummond, JT; Modrich, P; Sancar, A

A naturally occurring hPMS2 mutation can confer a dominant negative mutator phenotype

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28

124

OAAI

Nicolaides, NC; Littman, SJ; Modrich, P; Kinzler, KW; Vogelstein, B

Human MutLγ, the MLH1-MLH3 heterodimer, is an endonuclease that promotes DNA expansion 人mutl γ 是MLH1-MLH3的异二聚体，是一种促进DNA扩增的核酸内切酶。

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-02-03

OAAI

Kadyrova, Lyudmila Y.; Gujar, Vaibhavi; Burdett, Vickers; Modrich, Paul L.; Kadyrov, Farid A.

The mutagen and carcinogen cadmium is a high-affinity inhibitor of the zinc-dependent MutLα endonuclease

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2018-06-25

OAAI

Sherrer, Shanen M.; Penland, Elisabeth; Modrich, Paul

Interaction of proliferating cell nuclear antigen with PMS2 is required for MutLa activation and function in mismatch repair 增殖细胞核抗原与PMS2的相互作用是MutLa激活和错配修复功能所必需的

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2017-04-24

OAAI

Genschel, Jochen; Kadyrova, Lyudmila Y.; Iyer, Ravi R.; Dahal, Basanta K.; Kadyrov, Farid A.; Modrich, Paul

The C-terminal 20 Amino Acids of Drosophila Topoisomerase 2 Are Required for Binding to a BRCA1 C Terminus (BRCT) Domain-containing Protein, Mus101, and Fidelity of DNA Segregation

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2016-06-01

OAAI

Chen, Yu-tsung Shane; Wu, Jianhong; Modrich, Paul; Hsieh, Tao-shih

Mechanisms in E. coli and Human Mismatch Repair (Nobel Lecture)

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2016-05-20

OAAI

Modrich, Paul

MutL traps MutS at a DNA mismatch

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2015-08-17

OAAI

Qiu, Ruoyi; Sakato, Miho; Sacho, Elizabeth J.; Wilkins, Hunter; Zhang, Xingdong; Modrichd, Paul; Hingorani, Manju M.; Erie, Dorothy A.; Weninger, Keith R.

Hydrolytic function of Exo1 in mammalian mismatch repair

NUCLEIC ACIDS RESEARCH

IF13.1

2014-05-14

OAAI

Shao, Hongbing; Baitinger, Celia; Soderblom, Erik J.; Burdett, Vickers; Modrich, Paul

Coupling of Human DNA Excision Repair and the DNA Damage Checkpoint in a Defined in Vitro System*在定义的体外系统中，人类DNA切除修复和DNA损伤检查点的耦合 *

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2014-02-01

OAAI

Lindsey-Boltz, Laura A.; Kemp, Michael G.; Reardon, Joyce T.; Derocco, Vanessa; Iyer, Ravi R.; Modrich, Paul; Sancar, Aziz

Extrahelical (CAG)/(CTG) triplet repeat elements support proliferating cell nuclear antigen loading and MutLα endonuclease activation

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2013-07-09

OAAI

Pluciennik, Anna; Burdett, Vickers; Baitinger, Celia; Iyer, Ravi R.; Shi, Kevin; Modrich, Paul

Christian Raetz: Scientist and Friend Extraordinaire

ANNUAL REVIEW OF BIOCHEMISTRY

IF0

2013-06-02

OAAI

Dowhan, William; Nikaido, Hiroshi; Stubbe, JoAnne; Kozarich, John W.; Wickner, William T.; Russell, David W.; Garrett, Teresa A.; Brozek, Kathryn; Modrich, Paul

PARP-1 enhances the mismatch-dependence of 5'-directed excision in human mismatch repair in vitro

DNA REPAIR

IF2.7

2011-11-01

OAAI

Liu, Yiyong; Kadyrov, Farid A.; Modrich, Paul

PCNA function in the activation and strand direction of MutLα endonuclease in mismatch repair

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2010-08-16

266

OAAI

Pluciennik, Anna; Dzantiev, Leonid; Iyer, Ravi R.; Constantin, Nicoleta; Kadyrov, Farid A.; Modrich, Paul

PMS2 endonuclease activity has distinct biological functions and is essential for genome maintenance PMS2核酸内切酶活性具有独特的生物学功能，对于基因组维持至关重要

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2010-07-12

OAAI

van Oers, Johanna M. M.; Roa, Sergio; Werling, Uwe; Liu, Yiyong; Genschel, Jochen; Hou, Harry, Jr.; Sellers, Rani S.; Modrich, Paul; Scharff, Matthew D.; Edelmann, Winfried

Structure of the Endonuclease Domain of MutL: Unlicensed to Cut

MOLECULAR CELL

IF16.6

2010-07-01

122

OAAI

Pillon, Monica C.; Lorenowicz, Jessica J.; Uckelmann, Michael; Klocko, Andrew D.; Mitchell, Ryan R.; Chung, Yu Seon; Modrich, Paul; Walker, Graham C.; Simmons, Lyle A.; Friedhoff, Peter; Guarne, Alba

MutLα and Proliferating Cell Nuclear Antigen Share Binding Sites on MutSβ

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2010-04-01

OAAI

Iyer, Ravi R.; Pluciennik, Anna; Genschel, Jochen; Tsai, Miaw-Sheue; Beese, Lorena S.; Modrich, Paul

Interactions of Human Mismatch Repair Proteins MutSα and MutLα with Proteins of the ATR-Chk1 Pathway

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2010-02-01

OAAI

Liu, Yiyong; Fang, Yanan; Shao, Hongbing; Lindsey-Boltz, Laura; Sancar, Aziz; Modrich, Paul