David Oldach - Publications, H-index & Citations

David Oldach

nih national institute of allergy & infectious diseases (niaid)

35H指数

112论文数

5.5K被引数

收录论文 43

发表时间

Selective Impact on Regulatory T cell with Sustained Functional Phenotype by the IL-2 Mutein VIS171 in a Nonhuman Primate Model 选择性影响具有持续功能表型的调节性T细胞，IL-2变构蛋白VIS171在非人灵长类动物模型中的作用

American Journal of Transplantation

IF8.2

2026-03-16

PREAI

Davide Schiliró; Matt Tunbridge; Nolan J. Brown; Joshua Lopez; Tammy Tollison; Ethan Smith; Joseph Ladowski; Alessandro Martinino; Meghan Hu; Allison Schwalb; Janghoon Yoon; Rafaela Belloni; John J. O’Neil; Luke N. Robinson; Asher D. Schachter; Gregory J. Babcock; David Oldach; Xinxia Peng; H. Kay Chung; Stuart Knechtle

Polyclonal and Monoclonal Antibodies for the Treatment and Prevention of Influenza 多克隆和单克隆抗体在流感治疗与预防中的应用

JOURNAL OF INFECTIOUS DISEASES

IF4.5

2025-10-15

OAAI

Beigel, John H.; Oldach, David

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of VIS649 (Sibeprenlimab), an APRIL-Neutralizing IgG2 Monoclonal Antibody, in Healthy Volunteers

KIDNEY INTERNATIONAL REPORTS

IF5.7

2022-05-01

OAAI

Mathur, Mohit; Barratt, Jonathan; Suzuki, Yusuke; Engler, Frank; Pasetti, Marcela F.; Yarbrough, Jill; Sloan, Susan; Oldach, David

Solithromycin versus ceftriaxone plus azithromycin for the treatment of uncomplicated genital gonorrhoea (SOLITAIRE-U): a randomised phase 3 non-inferiority trial

LANCET INFECTIOUS DISEASES

IF31

2019-08-01

OAAI

Chen, Marcus Y.; McNulty, Anna; Avery, Ann; Whiley, David; Tabrizi, Sepehr N.; Hardy, Dwight; Das, Anita F.; Nenninger, Ashley; Fairley, Christopher K.; Hocking, Jane S.; Bradshaw, Catriona S.; Donovan, Basil; Howden, Benjamin P.; Oldach, David

Analyzing the Mechanisms Behind Macrolide Antibiotic-Induced Liver Injury Using Quantitative Systems Toxicology Modeling

PHARMACEUTICAL RESEARCH

IF4.3

2019-02-07

OAAI

Woodhead, Jeffrey L.; Yang, Kyunghee; Oldach, David; MacLauchlin, Chris; Fernandes, Prabhavathi; Watkins, Paul B.; Siler, Scott Q.; Howell, Brett A.

Safety and efficacy of monoclonal antibody VIS410 in adults with uncomplicated influenza A infection: Results from a randomized, double-blind, phase-2, placebo-controlled study

EBIOMEDICINE

IF10.8

2019-02-01

OAAI

Hershberger, Ellie; Sloan, Susan; Narayan, Kristin; Hay, Catherine A.; Smith, Patrick; Engler, Rank; Jeeninga, Rienk; Smits, Saskia; Trevejo, Jose; Shriver, Zach; Oldach, David

Solithromycin treatment for 13 weeks improves histological parameters in nonalcoholic steatohepatitis: results of an ongoing pilot study

JOURNAL OF HEPATOLOGY

IF33

2017-01-01

PREAI

Dobbins, R.; Gholam, P.; Ertel, S.; Furey, N.; Baskaran, G. M.; Goodman, Z.; Oldach, D.; Fernandes, P.

A Randomized Study Evaluating Oral Fusidic Acid (CEM-102) in Combination With Oral Rifampin Compared With Standard-of-Care Antibiotics for Treatment of Prosthetic Joint Infections: A Newly Identified Drug-Drug Interaction

CLINICAL INFECTIOUS DISEASES

IF7.3

2016-09-28

OAAI

Pushkin, Richard; Iglesias-Ussel, Maria D.; Keedy, Kara; MacLauchlin, Chris; Mould, Diane R.; Berkowitz, Richard; Kreuzer, Stephan; Darouiche, Rabih; Oldach, David; Fernandes, Prabha

SOLITAIRE-IV: A Randomized, Double-Blind, Multicenter Study Comparing the Efficacy and Safety of Intravenous-to-Oral Solithromycin to Intravenous-to-Oral Moxifloxacin for Treatment of Community-Acquired Bacterial Pneumonia

CLINICAL INFECTIOUS DISEASES

IF7.3

2016-07-22

OAAI

File, Thomas M., Jr.; Rewerska, Barbara; Vucinic-Mihailovic, Violeta; Gonong, Joven Roque V.; Das, Anita F.; Keedy, Kara; Taylor, David; Sheets, Amanda; Fernandes, Prabhavathi; Oldach, David; Jamieson, Brian D.

Efficacy and safety of oral solithromycin versus oral moxifloxacin for treatment of community-acquired bacterial pneumonia: a global, double-blind, multicentre, randomised, active-controlled, non-inferiority trial (SOLITAIRE-ORAL)

LANCET INFECTIOUS DISEASES

IF31

2016-04-01

PREAI

Barrera, Carlos M.; Mykietiuk, Analia; Metev, Hristo; Nitu, Mimi Floarea; Karimjee, Najumuddin; Doreski, Pablo Alexis; Mitha, Ismail; Tanaseanu, Cristina Mihaela; Molina, Joseph McDermott; Antonovsky, Yuri; Van Rensburg, Dirkie Johanna; Rowe, Brian H.; Flores-Figueroa, Jose; Rewerska, Barbara; Clark, Kay; Keedy, Kara; Sheets, Amanda; Scott, Drusilla; Horwith, Gary; Das, Anita F.; Jamieson, Brian; Fernandes, Prabhavathi; Oldach, David

LATE-BREAKING ABSTRACT: Oral solithromycin has a favorable profile versus oral moxifloxacin for treatment of adult community-acquired pneumonia (CABP) in elderly patients and those with COPD or asthma

EUROPEAN RESPIRATORY JOURNAL

IF21

2015-10-30

PREAI

Oldach, David; Luna, Carlos; Szabo, Peter; Mitha, Ismail; Tanaseanu, Cristina; Doreski, Alexis; Barrera, Carlos; Das, Anita; Keedy, Kara; Jamieson, Brian; Fernandes, Prabhavathi

Results from a Phase 3 trial in Moderate to Moderately Severe Community Acquired Bacterial Pneumonia (CABP) Treated As Outpatients With a New Oral Macrolide, Solithromycin

CHEST

IF8.6

2015-10-01

PREAI

Oldach, David; Barrera, Carlos; Rowe, Brian; Nitu, Floarea Mimi; Mykietiuk, Analia; Metev, Hristo; Laabs, Jessica; Mitha, Ismail; Tanaseanu, Cristina Mihaela; Molina, Joseph McDermott; Antonovsky, Yuri; Van Rensburg, Dirkie Johanna; Flores, Jose; Sokolowska, Barbara; Doreski, Alexis; Das, Anita; Clark, Kay; Jamieson, Brian; Sheets, Amanda; Keedy, Kara; Fernandes, Prabhavathi

Antibiotic Usage and the Development of Resistance

CLINICAL INFECTIOUS DISEASES

IF7.3

2015-03-10

OAAI

Fernandes, Prabhavathi; Oldach, David

A PHASE II, DOSE RANGING STUDY TO EVALUATE THE EFFICACY AND SAFETY OF SINGLE-DOSE ORAL SOLITHROMYCIN (CEM-101) FOR TREATMENT OF PATIENTS WITH UNCOMPLICATED UROGENITAL GONORRHOEA

SEXUALLY TRANSMITTED INFECTIONS

IF2.9

2013-07-13

OAAI

Hook, E. W., III; Jamieson, B. D.; Oldach, D.; Harbison, H.; Whittington, A.; Fernandes, P.

Randomized, Double-Blind, Multicenter Phase 2 Study Comparing the Efficacy and Safety of Oral Solithromycin (CEM-101) to Those of Oral Levofloxacin in the Treatment of Patients with Community-Acquired Bacterial Pneumonia

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2013-06-01

OAAI

Oldach, David; Clark, Kay; Schranz, Jennifer; Das, Anita; Craft, J. Carl; Scott, Drusilla; Jamieson, Brian D.; Fernandes, Prabhavathi

The protease inhibitor, GS-9256, and non-nucleoside polymerase inhibitor tegobuvir alone, with ribavirin, or pegylated interferon plus ribavirin in hepatitis C

HEPATOLOGY

IF15.8

2012-03-01

105

PREAI

Zeuzem, Stefan; Buggisch, Peter; Agarwal, Kosh; Marcellin, Patrick; Sereni, Daniel; Klinker, Hartwig; Moreno, Christophe; Zarski, Jean-Pierre; Horsmans, Yves; Mo, Hongmei; Arterburn, Sarah; Knox, Steven; Oldach, David; McHutchison, John G.; Manns, Michael P.; Foster, Graham R.

EMERGENCE AND PERSISTENCE OF NS5B MUTATIONS FOLLOWING COMBINATION TREATMENT WITH TEGOBUVIR (GS-9190) PLUS STANDARD OF CARE-LONG-TERM FOLLOW-UP FROM THE PHASE IIB STUDY GS-US-196-0103

JOURNAL OF HEPATOLOGY

IF33

2011-03-01

OAAI

Hebner, C.; Harris, J.; Oldach, D.; Miller, M. D.; Mo, H.

CHARACTERIZATION OF VIRAL RESISTANCE MUTATIONS IN GENOTYPE 1 HCV PATIENTS RECEIVING COMBINATION THERAPY WITH A PROTEASE INHIBITOR AND A POLYMERASE INHIBITOR WITH OR WITHOUT RIBAVIRIN

JOURNAL OF HEPATOLOGY

IF33

2011-03-01

OAAI

Mo, H.; Harris, J.; Bae, A.; Hebner, C.; Wong, K.; Delaney, W.; Oldach, D.; Miller, M. D.