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收藏Manufacturing a chimpanzee adenovirus-vectored SARS-CoV-2 vaccine to meet global needs
Joe, Carina C. D.; Jiang, Jinlin; Linke, Thomas; Li, Yuanyuan; Fedosyuk, Sofiya; Gupta, Gaurav; Berg, Adam; Segireddy, Rameswara R.; Mainwaring, David; Joshi, Amar; Cashen, Paul; Rees, Byron; Chopra, Nitin; Nestola, Piergiuseppe; Humphreys, Jonathan; Davies, Sarah; Smith, Nick; Bruce, Scott; Verbart, Dennis; Bormans, Daan; Knevelman, Carol; Woodyer, Mark; Davies, Lee; Cooper, Lisa; Kapanidou, Maria; Bleckwenn, Nicole; Pappas, Daniel; Lambe, Teresa; Smith, Daniel C.; Green, Catherine M.; Venkat, Raghavan; Ritchie, Adam J.; Gilbert, Sarah C.; Turner, Richard; Douglas, Alexander D. 分享 收藏 T cell and antibody responses induced by a single dose of ChAdOx1 nCoV-19 (AZD1222) vaccine in a phase 1/2 clinical trial (vol 27, pg 270, 2021)Ewer, Katie J.; Barrett, Jordan R.; Belij-Rammerstorfer, Sandra; Sharpe, Hannah; Makinson, Rebecca; Morter, Richard; Flaxman, Amy; Wright, Daniel; Bellamy, Duncan; Bittaye, Mustapha; Dold, Christina; Provine, Nicholas M.; Aboagye, Jeremy; Fowler, Jamie; Silk, Sarah E.; Alderson, Jennifer; Aley, Parvinder K.; Angus, Brian; Berrie, Eleanor; Bibi, Sagida; Cicconi, Paola; Clutterbuck, Elizabeth A.; Chelysheva, Irina; Folegatti, Pedro M.; Fuskova, Michelle; Green, Catherine M.; Jenkin, Daniel; Kerridge, Simon; Lawrie, Alison; Minassian, Angela M.; Moore, Maria; Mujadidi, Yama; Plested, Emma; Poulton, Ian; Ramasamy, Maheshi N.; Robinson, Hannah; Song, Rinn; Snape, Matthew D.; Tarrant, Richard; Voysey, Merryn; Watson, Marion E. E.; Douglas, Alexander D.; Hill, Adrian V. S.; Gilbert, Sarah C.; Pollard, Andrew J.; Lambe, Teresa 分享 收藏 Phase 1/2 trial of SARS-CoV-2 vaccine ChAdOx1 nCoV-19 with a booster dose induces multifunctional antibody responses (vol 27, pg 279, 2021)Barrett, Jordan R.; Belij-Rammerstorfer, Sandra; Dold, Christina; Ewer, Katie J.; Folegatti, Pedro M.; Gilbride, Ciaran; Halkerston, Rachel; Hill, Jennifer; Jenkin, Daniel; Stockdale, Lisa; Verheul, Marije K.; Aley, Parvinder K.; Angus, Brian; Bellamy, Duncan; Berrie, Eleanor; Bibi, Sagida; Bittaye, Mustapha; Carroll, Miles W.; Cavell, Breeze; Clutterbuck, Elizabeth A.; Edwards, Nick; Flaxman, Amy; Fuskova, Michelle; Gorringe, Andrew; Hallis, Bassam; Kerridge, Simon; Lawrie, Alison M.; Linder, Aline; Liu, Xinxue; Madhavan, Meera; Makinson, Rebecca; Mellors, Jack; Minassian, Angela; Moore, Maria; Mujadidi, Yama; Plested, Emma; Poulton, Ian; Ramasamy, Maheshi N.; Robinson, Hannah; Rollier, Christine S.; Song, Rinn; Snape, Matthew D.; Tarrant, Richard; Taylor, Stephen; Thomas, Kelly M.; Voysey, Merryn; Watson, Marion E. E.; Wright, Daniel; Douglas, Alexander D.; Green, Catherine M.; Hill, Adrian V. S.; Lambe, Teresa; Gilbert, Sarah; Pollard, Andrew J. 分享 收藏 Native-like SARS-CoV-2 Spike Glycoprotein Expressed by ChAdOx1 nCoV-19/AZD1222 VaccineWatanabe, Yasunori; Mendonca, Luiza; Allen, Elizabeth R.; Howe, Andrew; Lee, Mercede; Allen, Joel D.; Chawla, Himanshi; Pulido, David; Donnellan, Francesca; Davies, Hannah; Ulaszewska, Marta; Belij-Rammerstorfer, Sandra; Morris, Susan; Krebs, Anna-Sophia; Dejnirattisai, Wanwisa; Mongkolsapaya, Juthathip; Supasa, Piyada; Screaton, Gavin R.; Green, Catherine M.; Lambe, Teresa; Zhang, Peijun; Gilbert, Sarah C.; Crispin, Max 分享 收藏 Efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 variant of concern 202012/01 (B.1.1.7): an exploratory analysis of a randomised controlled trialChAdOx1 nCoV-19 (AZD1222) 疫苗对SARS-CoV-2相关变异202012/01 (B.1.1.7) 的疗效: 一项随机对照试验的探索性分析Emary, Katherine R. W.; Golubchik, Tanya; Aley, Parvinder K.; Ariani, Cristina, V; Angus, Brian; Bibi, Sagida; Blane, Beth; Bonsall, David; Cicconi, Paola; Charlton, Sue; Clutterbuck, Elizabeth A.; Collins, Andrea M.; Cox, Tony; Darton, Thomas C.; Dold, Christina; Douglas, Alexander D.; Duncan, Christopher J. A.; Ewer, Katie J.; Flaxman, Amy L.; Faust, Saul N.; Ferreira, Daniela M.; Feng, Shuo; Finn, Adam; Folegatti, Pedro M.; Fuskova, Michelle; Galiza, Eva; Goodman, Anna L.; Green, Catherine M.; Green, Christopher A.; Greenland, Melanie; Hallis, Bassam; Heath, Paul T.; Hay, Jodie; Hill, Helen C.; Jenkin, Daniel; Kerridge, Simon; Lazarus, Rajeka; Libri, Vincenzo; Lillie, Patrick J.; Ludden, Catherine; Marchevsky, Natalie G.; Minassian, Angela M.; McGregor, Alastair C.; Mujadidi, Yama F.; Phillips, Daniel J.; Plested, Emma; Pollock, Katrina M.; Robinson, Hannah; Smith, Andrew; Song, Rinn; Snape, Matthew D.; Sutherland, Rebecca K.; Thomson, Emma C.; Toshner, Mark; Turner, David P. J.; Vekemans, Johan; Villafana, Tonya L.; Williams, Christopher J.; Hill, Adrian V. S.; Lambe, Teresa; Gilbert, Sarah C.; Voysey, Merryn; Ramasamy, Maheshi N.; Pollard, Andrew J. 分享 收藏 When the genome bluffs: a tandem duplication event during generation of a novel Agmo knockout mouse model fools routine genotypingSailer, Sabrina; Coassin, Stefan; Lackner, Katharina; Fischer, Caroline; McNeill, Eileen; Streiter, Gertraud; Kremser, Christian; Maglione, Manuel; Green, Catherine M.; Moralli, Daniela; Moschen, Alexander R.; Keller, Markus A.; Golderer, Georg; Werner-Felmayer, Gabriele; Tegeder, Irmgard; Channon, Keith M.; Davies, Benjamin; Werner, Ernst R.; Watschinger, Katrin 分享 收藏 Endogenous aldehyde accumulation generates genotoxicity and exhaled biomarkers in esophageal adenocarcinoma食管腺癌中内源性醛积累产生遗传毒性和呼出生物标志物Antonowicz, Stefan; Bodai, Zsolt; Wiggins, Tom; Markar, Sheraz R.; Boshier, Piers R.; Goh, Yan Mei; Adam, Mina E.; Lu, Haonan; Kudo, Hiromi; Rosini, Francesca; Goldin, Robert; Moralli, Daniela; Green, Catherine M.; Peters, Chris J.; Habib, Nagy; Gabra, Hani; Fitzgerald, Rebecca C.; Takats, Zoltan; Hanna, George B. 分享 收藏 Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four randomised trialsVoysey, Merryn; Clemens, Sue Ann Costa; Madhi, Shabir A.; Weckx, Lily Y.; Folegatti, Pedro M.; Aley, Parvinder K.; Angus, Brian; Baillie, Vicky L.; Barnabas, Shaun L.; Bhorat, Qasim E.; Bibi, Sagida; Briner, Carmen; Cicconi, Paola; Clutterbuck, Elizabeth A.; Collins, Andrea M.; Cutland, Clare L.; Darton, Thomas C.; Dheda, Keertan; Dold, Christina; Duncan, Christopher J. A.; Emary, Katherine R. W.; Ewer, Katie J.; Flaxman, Amy; Fairlie, Lee; Faust, Saul N.; Feng, Shuo; Ferreira, Daniela M.; Finn, Adam; Galiza, Eva; Goodman, Anna L.; Green, Catherine M.; Green, Christopher A.; Greenland, Melanie; Hill, Catherine; Hill, Helen C.; Hirsch, Ian; Izu, Alane; Jenkin, Daniel; Joe, Carina C. D.; Kerridge, Simon; Koen, Anthonet; Kwatra, Gaurav; Lazarus, Rajeka; Libri, Vincenzo; Lillie, Patrick J.; Marchevsky, Natalie G.; Marshall, Richard P.; Mendes, Ana V. A.; Milan, Eveline P.; Minassian, Angela M.; McGregor, Alastair; Mujadidi, Yama F.; Nana, Anusha; Padayachee, Sherman D.; Phillips, Daniel J.; Pittella, Ana; Plested, Emma; Pollock, Katrina M.; Ramasamy, Maheshi N.; Ritchie, Adam J.; Robinson, Hannah; Schwarzbold, Alexandre V.; Smith, Andrew; Song, Rinn; Snape, Matthew D.; Sprinz, Eduardo; Sutherland, Rebecca K.; Thomson, Emma C.; Torok, M. Estee; Toshner, Mark; Turner, David P. J.; Vekemans, Johan; Villafana, Tonya L.; White, Thomas; Williams, Christopher J.; Douglas, Alexander D.; Hill, Adrian V. S.; Lambe, Teresa; Gilbert, Sarah C.; Pollard, Andrew J. 分享 收藏 Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UKChAdOx1 nCoV-19疫苗 (AZD1222) 抗SARS-CoV-2的安全性和有效性: 对巴西、南非和英国的四项随机对照试验的中期分析Voysey, Merryn; Clemens, Sue Ann Costa; Madhi, Shabir A.; Weckx, Lily Y.; Folegatti, Pedro M.; Aley, Parvinder K.; Angus, Brian; Baillie, Vicky L.; Barnabas, Shaun L.; Bhorat, Qasim E.; Bibi, Sagida; Briner, Carmen; Cicconi, Paola; Collins, Andrea M.; Colin-Jones, Rachel; Cutland, Clare L.; Darton, Thomas C.; Dheda, Keertan; Duncan, Christopher J. A.; Emary, Katherine R. W.; Ewer, Katie J.; Fairlie, Lee; Faust, Saul N.; Feng, Shuo; Ferreira, Daniela M.; Finn, Adam; Goodman, Anna L.; Green, Catherine M.; Green, Christopher A.; Heath, Paul T.; Hill, Catherine; Hill, Helen; Hirsch, Ian; Hodgson, Susanne H. C.; Izu, Alane; Jackson, Susan; Jenkin, Daniel; Joe, Carina C. D.; Kerridge, Simon; Koen, Anthonet; Kwatra, Gaurav; Lazarus, Rajeka; Lawrie, Alison M.; Lelliott, Alice; Libri, Vincenzo; Lillie, Patrick J.; Mallory, Raburn; Mendes, Ana V. A.; Milan, Eveline P.; Minassian, Angela M.; McGregor, Alastair; Morrison, Hazel; Mujadidi, Yama F.; Nana, Anusha; O'Reilly, Peter J.; Padayachee, Sherman D.; Pittella, Ana; Plested, Emma; Pollock, Katrina M.; Ramasamy, Maheshi N.; Rhead, Sarah; Schwarzbold, Alexandre V.; Singh, Nisha; Smith, Andrew; Song, Rinn; Snape, Matthew D.; Sprinz, Eduardo; Sutherland, Rebecca K.; Tarrant, Richard; Thomson, Emma C.; Torok, M. Estee; Toshner, Mark; Turner, David P. J.; Vekemans, Johan; Villafana, Tonya L.; Watson, Marion E. E.; Williams, Christopher J.; Douglas, Alexander D.; Hill, Adrian V. S.; Lambe, Teresa; Gilbert, Sarah C.; Pollard, Andrew J. 分享 收藏 T cell and antibody responses induced by a single dose of ChAdOx1 nCoV-19 (AZD1222) vaccine in a phase 1/2 clinical trialEwer, Katie J.; Barrett, Jordan R.; Belij-Rammerstorfer, Sandra; Sharpe, Hannah; Makinson, Rebecca; Morter, Richard; Flaxman, Amy; Wright, Daniel; Bellamy, Duncan; Bittaye, Mustapha; Dold, Christina; Provine, Nicholas M.; Aboagye, Jeremy; Fowler, Jamie; Silk, Sarah E.; Alderson, Jennifer; Aley, Parvinder K.; Angus, Brian; Berrie, Eleanor; Bibi, Sagida; Cicconi, Paola; Clutterbuck, Elizabeth A.; Chelysheva, Irina; Folegatti, Pedro M.; Fuskova, Michelle; Green, Catherine M.; Jenkin, Daniel; Kerridge, Simon; Lawrie, Alison; Minassian, Angela M.; Moore, Maria; Mujadidi, Yama; Plested, Emma; Poulton, Ian; Ramasamy, Maheshi N.; Robinson, Hannah; Song, Rinn; Snape, Matthew D.; Tarrant, Richard; Voysey, Merryn; Watson, Marion E. E.; Douglas, Alexander D.; Hill, Adrian V. S.; Gilbert, Sarah C.; Pollard, Andrew J.; Lambe, Teresa 分享 收藏 Phase 1/2 trial of SARS-CoV-2 vaccine ChAdOx1 nCoV-19 with a booster dose induces multifunctional antibody responsesBarrett, Jordan R.; Belij-Rammerstorfer, Sandra; Dold, Christina; Ewer, Katie J.; Folegatti, Pedro M.; Gilbride, Ciaran; Halkerston, Rachel; Hill, Jennifer; Jenkin, Daniel; Stockdale, Lisa; Verheul, Marije K.; Aley, Parvinder K.; Angus, Brian; Bellamy, Duncan; Berrie, Eleanor; Bibi, Sagida; Bittaye, Mustapha; Carroll, Miles W.; Cavell, Breeze; Clutterbuck, Elizabeth A.; Edwards, Nick; Flaxman, Amy; Fuskova, Michelle; Gorringe, Andrew; Hallis, Bassam; Kerridge, Simon; Lawrie, Alison M.; Linder, Aline; Liu, Xinxue; Madhavan, Meera; Makinson, Rebecca; Mellors, Jack; Minassian, Angela; Moore, Maria; Mujadidi, Yama; Plested, Emma; Poulton, Ian; Ramasamy, Maheshi N.; Robinson, Hannah; Rollier, Christine S.; Song, Rinn; Snape, Matthew D.; Tarrant, Richard; Taylor, Stephen; Thomas, Kelly M.; Voysey, Merryn; Watson, Marion E. E.; Wright, Daniel; Douglas, Alexander D.; Green, Catherine M.; Hill, Adrian V. S.; Lambe, Teresa; Gilbert, Sarah; Pollard, Andrew J. 分享 收藏 Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind, randomised, controlled, phase 2/3 trialChAdOx1 nCoV-19疫苗在年轻人和老年人中施用的prime-boost方案的安全性和免疫原性 (COV002): 单盲，随机，对照，2/3期试验Ramasamy, Maheshi N.; Minassian, Angela M.; Ewer, Katie J.; Flaxman, Amy L.; Folegatti, Pedro M.; Owens, Daniel R.; Voysey, Merryn; Aley, Parvinder K.; Angus, Brian; Babbage, Gavin; Belij-Rammerstorfer, Sandra; Berry, Lisa; Bibi, Sagida; Bittaye, Mustapha; Cathie, Katrina; Chappell, Harry; Charlton, Sue; Cicconi, Paola; Clutterbuck, Elizabeth A.; Colin-Jones, Rachel; Dold, Christina; Emary, Katherine R. W.; Fedosyuk, Sofiya; Fuskova, Michelle; Gbesemete, Diane; Green, Catherine; Hallis, Bassam; Hou, Mimi M.; Jenkin, Daniel; Joe, Carina C. D.; Kelly, Elizabeth J.; Kerridge, Simon; Lawrie, Alison M.; Lelliott, Alice; Lwin, May N.; Makinson, Rebecca; Marchevsky, Natalie G.; Mujadidi, Yama; Munro, Alasdair P. S.; Pacurar, Mihaela; Plested, Emma; Rand, Jade; Rawlinson, Thomas; Rhead, Sarah; Robinson, Hannah; Ritchie, Adam J.; Ross-Russell, Amy L.; Saich, Stephen; Singh, Nisha; Smith, Catherine C.; Snape, Matthew D.; Song, Rinn; Tarrant, Richard; Themistocleous, Yrene; Thomas, Kelly M.; Villafana, Tonya L.; Warren, Sarah C.; Watson, Marion E. E.; Douglas, Alexander D.; Hill, Adrian V. S.; Lambe, Teresa; Gilbert, Sarah C.; Faust, Saul N.; Pollard, Andrew J. 分享 收藏 Specific Mechanisms of Chromosomal Instability Indicate Therapeutic Sensitivities in High-Grade Serous Ovarian CarcinomaTamura, Naoka; Shaikh, Nadeem; Muliaditan, Daniel; Soliman, Tanya N.; McGuinness, Jennifer R.; Maniati, Eleni; Moralli, Daniela; Durin, Mary-Anne; Green, Catherine M.; Balkwill, Frances R.; Wang, Jun; Curtius, Kit; McClelland, Sarah E. 分享 收藏 分享 收藏 Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trialChAdOx1 nCoV-19疫苗抗SARS-CoV-2的安全性和免疫原性: 1/2期单盲随机对照试验的初步报告Folegatti, Pedro M.; Ewer, Katie J.; Aley, Parvinder K.; Angus, Brian; Becker, Stephan; Belij-Rammerstorfer, Sandra; Bellamy, Duncan; Bibi, Sagida; Bittaye, Mustapha; Clutterbuck, Elizabeth A.; Dold, Christina; Faust, Saul N.; Finn, Adam; Flaxman, Amy L.; Hallis, Bassam; Heath, Paul; Jenkin, Daniel; Lazarus, Rajeka; Makinson, Rebecca; Minassian, Angela M.; Pollock, Katrina M.; Ramasamy, Maheshi; Robinson, Hannah; Snape, Matthew; Tarrant, Richard; Voysey, Merryn; Green, Catherine; Douglas, Alexander D.; Hill, Adrian V. S.; Lambe, Teresa; Gilbert, Sarah C.; Pollard, Andrew J. 分享 收藏 The Configuration of RPA, RAD51, and DMC1 Binding in Meiosis Reveals the Nature of Critical Recombination IntermediatesHinch, Anjali Gupta; Becker, Philipp W.; Li, Tao; Moralli, Daniela; Zhang, Gang; Bycroft, Clare; Green, Catherine; Keeney, Scott; Shi, Qinghua; Davies, Benjamin; Donnelly, Peter 分享 收藏 A living biobank of ovarian cancer ex vivo models reveals profound mitotic heterogeneityNelson, Louisa; Tighe, Anthony; Golder, Anya; Littler, Samantha; Bakker, Bjorn; Moralli, Daniela; Baker, Syed Murtuza; Donaldson, Ian J.; Spierings, Diana C. J.; Wardenaar, Rene; Neale, Bethanie; Burghel, George J.; Winter-Roach, Brett; Edmondson, Richard; Clamp, Andrew R.; Jayson, Gordon C.; Desai, Sudha; Green, Catherine M.; Hayes, Andy; Foijer, Floris; Morgan, Robert D.; Taylor, Stephen S. 分享 收藏 分享 收藏 Migration through physical constraints is enabled by MAPK-induced cell softening via actin cytoskeleton re-organizationRudzka, Dominika A.; Spennati, Giulia; McGarry, David J.; Chim, Ya-Hua; Neilson, Matthew; Ptak, Aleksandra; Munro, June; Kalna, Gabriela; Hedley, Ann; Moralli, Daniela; Green, Catherine; Mason, Susan; Blyth, Karen; Mullin, Margaret; Yin, Huabing; Olson, Michael F. 分享 收藏 
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