Ingrid Fleming - Publications, H-index & Citations

Ingrid Fleming

goethe university frankfurt

100H指数

542论文数

3.6W被引数

收录论文 263

发表时间

Soluble epoxide hydrolase drives neurovascular dysfunction in a model of amyloidosis 可溶性环氧水解酶驱动淀粉样变性模型中的神经血管功能障碍

Brain

IF11.7

2026-05-22

PREAI

Murphy DeMeglio; Eloah S De Biasi; Peter Breunig; Michael Candlish; Christina Sauerland; Stefan Günther; Haruya Kawase; Blanca Peguera; Christine Bohnstaedt; Jochen Herms; Antonia Neubauer; Jonas J Neher; Peter R Nilsson; Jiong Hu; Susanne Hille; Oliver Müller; Amparo Acker-Palmer; Bruce D Hammock; T Michael Underhill; Stephan Junek; Stefan Offermanns; Ingrid Fleming; Jasmin K Hefendehl

Identification of unannotated microproteins involved in endothelial cell homeostasis, dysfunction and vascular disease 鉴定参与内皮细胞稳态、功能障碍和血管疾病的未注释微小蛋白

Cardiovascular Research

IF13.3

2026-05-19

OAAI

Mauro Siragusa; Johannes Graumann; Carsten Kuenne; Stefan Günther; Sylvia Jeratsch; Beyza Güven; Sebastian Süsser; Sweta Talyan; Bethlehem Bezuneh; Yves Matthess; Matteo Cartura; Xiaozhu Zhou; Haaglim Cho; Nadja Sachs; Lars Maegdefessel; Oliver J Müller; Christian Troidl; Holger M Nef; Mario Looso; Manuel Kaulich; Stefan Offermanns; Ingrid Fleming

Harnessing lipid-driven immunometabolic pathways in omental metastases to enhance immunotherapy in patients with ovarian cancer 利用网膜转移中脂质驱动的免疫代谢途径来增强卵巢癌患者的免疫治疗

Signal Transduction and Targeted Therapy

IF52.7

2026-03-04

OAAI

Meggy Suarez-Carmona; Mareike Hampel; Xin-Wen Zhang; Alexandra Pöchmann; Silke A. Grauling-Halama; Nektarios A. Valous; Pornpimol Charoentong; Dyke Ferber; Jannis Wissfeld; Alicia Höflich; Stanislas Goriely; Aurélie Detavernier; Abdulkader Azouz; Anthony Rongvaux; Sven Zukunft; Ingrid Fleming; Jürgen G. Okun; Vickie Baracos; Mathias Heikenwalder; Laurence Zitvogel; Xinyi Xu; Chenqi Xu; Michael Volkmar; Daniel Schraivogel; Lars Steinmetz; Junzo Hamanishi; Masaki Mandai; Matthias Gaida; Theresa Mokry; Johanna Nattenmüller; Oliver Sedlaczek; Nanna Monje; Roxana Schwab; Annette Hasenburg; Athanasios Mavratzas; Regina Johanna Boger; Frederik Marmé; Sarah Schott; Niels Halama

The PIEZO1 paradox: an ion channel at the crossroads of mechanics and metabolism in pulmonary disease PIEZO1悖论：在肺部疾病中连接力学与代谢的关键离子通道

Cardiovascular Research

IF13.3

2026-03-01

PREAI

Fleming, Ingrid

Soluble ST2 drives fulminant myocarditis progression via the IGF2R-YY1 mitochondrial axis 可溶性ST2通过IGF2R–YY1线粒体轴驱动爆发性心肌炎进展

European Heart Journal

IF35.6

2026-02-01

PREAI

Zhuang, Yan; Zhang, Zhuo; Li, Huihui; Abuduwufuer, Kudusi; Zhang, Donghui; Wen, Zheng; Rao, Xiaoquan; Chen, Chen; Fleming, Ingrid; Wang, Dao Wen

Lamin A/C-regulated cysteine catabolic flux modulates stem cell fate through epigenome reprogramming Lamin A/C调节的半胱氨酸分解代谢通量通过表观基因组重编程调节干细胞命运

Nature Metabolism

IF20.8

2026-01-28

OAAI

Yinuo Wang; Haojie Shi; Janina Wittig; Yonggang Ren; Julio Cordero; Matthias Dewenter; Jessica Mella; Abigail Buchwalter; Johannes Backs; Thomas Wieland; Joerg Heineke; Ingrid Fleming; Sofia-Iris Bibli; Gergana Dobreva

Sex and gender differences in coronary pathophysiology and ischaemic heart disease 性别差异在冠状动脉病理生理学和缺血性心脏病中的作用

European Heart Journal

IF35.6

2026-01-01

PREAI

Manfrini, Olivia; Tousoulis, Dimitris; Antoniades, Charalambos; Badimon, Lina; Bugiardini, Raffaele; Chieffo, Alaide; Crea, Filippo; De Luca, Giuseppe; Djordjevic-Dikic, Ana; Drenjancevic, Ines; Duncker, Dirk J.; Fleming, Ingrid; Gallinoro, Emanuele; Kunadian, Vijay; Galassi, Alfredo R.; Guzik, Tomasz J.; Masip, Josep; Merkus, Daphne; Milicic, Davor; Poss, Janine; Riou, Laurent; Sambola, Antonia; Trifunovic-Zamaklar, Danijela; Tycinska, Agnieszka; Vavlukis, Marija; Zdravkovic, Marija; Cenko, Edina; Padro, Teresa

Cystine import and oxidative catabolism fuel vascular growth and repair via nutrient-responsive histone acetylation 胱氨酸的摄取和氧化分解通过营养响应性组蛋白乙酰化促进血管生长和修复。

Cell Metabolism

IF30.9

2025-10-31

OAAI

Maria-Kyriaki Drekolia; Janina Mettner; Daiyu Wang; Fredy Delgado Lagos; Christian Koch; Dennis Hecker; Jeanette Eresch; Yifang Mao; Marion Bähr; Dieter Weichenhan; Julio Cordero; Janina Wittig; Boran Zhang; Hanyu Cui; Xiaoming Li; James A. Oo; Andreas Weigert; Mauro Siragusa; Stephan Klatt; Ingrid Fleming; Stefan Günther; Mario Looso; Ralf P. Brandes; Harald F. Langer; Andreas Papapetropoulos; Mahak Singhal; Marcel H. Schulz; Christoph Plass; Joerg Heineke; Gergana Dobreva; Jiong Hu; Sofia-Iris Bibli

Structure-Based Design of PROTACS for the Degradation of Soluble Epoxide Hydrolase 基于结构的PROTACS设计用于可溶性环氧合酶的降解

Journal of Medicinal Chemistry

IF6.8

2025-06-18

OAAI

Julia Schönfeld; Steffen Brunst; Ludmila Ciomirtan; Lena Willmer; Michel A. Chromik; Adarsh Kumar; Timo Froemel; Nick Liebisch; Arne Hackspacher; Johanna H. M. Ehrler; Lukas Wintermeier; Christina Hesse; Jan Fiedler; Jan Heering; Hinrich Freitag; Patrick Zardo; Hans-Gerd Fieguth; Astrid Brüggerhoff; Josefine Jakob; Björn Häupl; Lilia Weizel; Astrid Kaiser; Manfred Schubert-Zsilavecz; Thomas Oellerich; Ingrid Fleming; Nils H. Schebb; Robert Fürst; Aimo Kannt; Stefan Knapp; Ewgenij Proschak; Kerstin Hiesinger

The aryl hydrocarbon receptor and FOS mediate cytotoxicity induced by Acinetobacter baumannii 芳香烃受体和FOS介导鲍曼不动杆菌的细胞毒性

NATURE COMMUNICATIONS

IF15.7

2024-09-11

OAAI

Kew, Chun; Prieto-Garcia, Cristian; Bhattacharya, Anshu; Tietgen, Manuela; MacNair, Craig R.; Carfrae, Lindsey A.; Mello-Vieira, Joao; Klatt, Stephan; Cheng, Yi-Lin; Rathore, Rajeshwari; Gradhand, Elise; Fleming, Ingrid; Tan, Man-Wah; Goettig, Stephan; Kempf, Volkhard A. J.; Dikic, Ivan

Pericyte-to-Endothelial Cell Communication via Tunneling Nanotubes Is Disrupted by a Diol of Docosahexaenoic Acid 通过隧道纳米管的周细胞与内皮细胞的通讯被二十二碳六烯酸的二醇破坏

CELLS

IF5.2

2024-08-26

OAAI

Kempf, Sebastian; Popp, Ruediger; Naeem, Zumer; Froemel, Timo; Wittig, Ilka; Klatt, Stephan; Fleming, Ingrid

Inhibition of proline-rich tyrosine kinase 2 restores cardioprotection by remote ischaemic preconditioning in type 2 diabetes 抑制富含脯氨酸的酪氨酸激酶2可通过远隔缺血预处理恢复2型糖尿病的心脏保护作用

BRITISH JOURNAL OF PHARMACOLOGY

IF7.7

2024-07-02

OAAI

Erkens, Ralf; Duse, Dragos Andrei; Brum, Amanda; Chadt, Alexandra; Becher, Stefanie; Siragusa, Mauro; Quast, Christine; Muessig, Johanna; Roden, Michael; Cortese-Krott, Miriam; Ibanez, Borja; Lammert, Eckhard; Fleming, Ingrid; Jung, Christian; Al-Hasani, Hadi; Heusch, Gerd; Kelm, Malte

Hemojuvelin-mediated hepcidin induction requires both bone morphogenetic protein type I receptors ALK2 and ALK3 血巨肽介导的铁调素诱导需要I型骨形态发生蛋白受体ALK2和ALK3

BLOOD ADVANCES

IF7.1

2024-06-03

OAAI

Dogan, Deniz Y.; Urzica, Eugen I.; Hornung, Isabelle; Kastl, Philipp; Oguama, David; Fette, Franca M.; Nguyen, Lien H.; Rosenbauer, Frank; Zacharowski, Kai; Klingmueller, Ursula; Gradhand, Elise; von Knethen, Andreas; Popp, Ruediger; Fleming, Ingrid; Schrader, Lisa; Steinbicker, Andrea U.

Age-Dependent RGS5 Loss in Pericytes Induces Cardiac Dysfunction and Fibrosis 周细胞中年龄依赖性RGS5丢失诱导心功能障碍和纤维化

CIRCULATION RESEARCH

IF16.2

2024-05-10

OAAI

Tamiato, Anita; Tombor, Lukas S.; Fischer, Ariane; Muhly-Reinholz, Marion; Vanicek, Leah Rebecca; Togru, Buesra Nur; Neitz, Jessica; Glaser, Simone Franziska; Merten, Maximilian; Morales, David Rodriguez; Kwon, Jeonghyeon; Klatt, Stephan; Schumacher, Bianca; Guenther, Stefan; Abplanalp, Wesley T.; John, David; Fleming, Ingrid; Wettschureck, Nina; Dimmeler, Stefanie; Luxaen, Guillermo

Role of the soluble epoxide hydrolase in keratinocyte proliferation and sensitivity of skin to inflammatory stimuli 可溶性环氧化物水解酶在角质形成细胞增殖和皮肤对炎症刺激的敏感性中的作用

BIOMEDICINE & PHARMACOTHERAPY

IF7.5

2024-02-01

OAAI

Naeem, Zumer; Zukunft, Sven; Huard, Arnaud; Hu, Jiong; Hammock, Bruce D.; Weigert, Andreas; Fro, Timo; Fleming, Ingrid

Impaired Detoxification of Trans, Trans-2,4-Decadienal, an Oxidation Product from Omega-6 Fatty Acids, Alters Insulin Signaling, Gluconeogenesis and Promotes Microvascular Disease 反式，Trans-2，4-癸二烯醛 (一种来自Omega-6脂肪酸的氧化产物) 的解毒受损，改变胰岛素信号传导，糖异生并促进微血管疾病

ADVANCED SCIENCE

IF14.1

2023-12-07

OAAI

Qian, Xin; Klatt, Stephan; Bennewitz, Katrin; Wohlfart, David Philipp; Lou, Bowen; Meng, Ye; Buettner, Michael; Poschet, Gernot; Morgenstern, Jakob; Fleming, Thomas; Sticht, Carsten; Hausser, Ingrid; Fleming, Ingrid; Szendroedi, Julia; Nawroth, Peter Paul; Kroll, Jens

Disrupted Binding of Cystathionine γ-Lyase to p53 Promotes Endothelial Senescence 胱硫醚 γ-裂解酶与p53的结合破坏促进内皮衰老

CIRCULATION RESEARCH

IF16.2

2023-10-27

PREAI

Hu, Jiong; Leisegang, Matthias S.; Looso, Mario; Drekolia, Maria-Kyriaki; Wittig, Janina; Mettner, Janina; Karantanou, Christina; Kyselova, Anastasia; Dumbovic, Gabrjela; Li, Xiaoming; Li, Yuanyuan; Guenther, Stefan; John, David; Siragusa, Mauro; Zukunft, Sven; Oo, James A.; Wittig, Ilka; Hille, Susanne; Weigert, Andreas; Knapp, Stefan; Brandes, Ralf P.; Mueller, Oliver J.; Papapetropoulos, Andreas; Sigala, Fragiska; Dobreva, Gergana; Kojonazarov, Baktybek; Fleming, Ingrid; Bibli, Sofia-Iris

Epoxyeicosatrienoic Acids Prevent Cardiac Dysfunction in Viral Myocarditis via Interferon Type I Signaling 环氧二十碳三烯酸通过I型干扰素信号预防病毒性心肌炎的心功能障碍

CIRCULATION RESEARCH

IF16.2

2023-10-13

OAAI

Zhou, Zhou; Zhang, Min; Zhao, Chengcheng; Gao, Xu; Wen, Zheng; Wu, Junfang; Chen, Chen; Fleming, Ingrid; Hu, Jiong; Wang, Dao Wen

Perivascular adipose tissue as a source of therapeutic targets and clinical biomarkers A clinical consensus statement from the European Society of Cardiology Working Group on Coronary Pathophysiology and Micro-circulation 血管周围脂肪组织作为治疗靶点和临床生物标志物的来源欧洲心脏病学会冠状动脉病理生理学和微循环工作组的临床共识声明

EUROPEAN HEART JOURNAL

IF35.6

2023-08-21

OAAI

Antoniades, Charalambos; Tousoulis, Dimitris; Vavlukis, Marija; Fleming, Ingrid; Duncker, Dirk J.; Eringa, Etto; Manfrini, Olivia; Antonopoulos, Alexios S.; Oikonomou, Evangelos; Padro, Teresa; Trifunovic-Zamaklar, Danijela; De Luca, Giuseppe; Guzik, Tomasz; Cenko, Edina; Djordjevic-Dikic, Ana; Crea, Filippo

ADPGK-AS1 long noncoding RNA switches macrophage metabolic and phenotypic state to promote lung cancer growth ADPGK-AS1长链非编码RNA开关巨噬细胞代谢和表型状态促进肺癌生长

EMBO JOURNAL

IF8.3

2023-08-07

OAAI

Karger, Annika; Mansouri, Siavash; Leisegang, Matthias S.; Weigert, Andreas; Guenther, Stefan; Kuenne, Carsten; Wittig, Ilka; Zukunft, Sven; Klatt, Stephan; Aliraj, Blerina; Klotz, Laura, V; Winter, Hauke; Mahavadi, Poornima; Fleming, Ingrid; Ruppert, Clemens; Witte, Biruta; Alkoudmani, Ibrahim; Gattenloehner, Stefan; Grimminger, Friedrich; Seeger, Werner; Pullamsetti, Soni Savai; Savai, Rajkumar

研究方向