未登录 PDE5 and PDE10 inhibition activates cGMP/PKG signaling to block Wnt/β-catenin transcription, cancer cell growth, and tumor immunity Piazza, Gary A.; Ward, Antonio; Chen, Xi; Maxuitenko, Yulia; Coley, Alex; Aboelella, Nada S.; Buchsbaum, Donald J.; Boyd, Michael R.; Keeton, Adam B.; Zhou, Gang 分享 收藏
A novel PDE10/β-catenin pathway inhibitor, MCI-030, for the treatment of colorectal cancer Ward, Antonio B.; Chen, Xi; Valiyaveettil, Jacob; Lee, Kevin; Chang, Wen-Chi L.; Maxuitenko, Yulia; Ramirez-Alcantara, Veronica; Berry, Kristy; da Silva, Luciana Madeira; Zhu, Bing; Mattox, Tyler; Boyd, Michael R.; Keeton, Adam B.; Clapper, Margie L.; Cooper, Harry S.; Piazza, Gary A. 分享 收藏
A novel RAS inhibitor, MCI-062, inhibits colon tumor growth in vivo and activates antitumor immunity Keeton, Adam B.; Ward, Antonio; Chen, Xi; Valiyaveettil, Jacob; Zhu, Bing; Ramirez-Alcantara, Veronica; Maxuitenko, Yulia; Berry, Kristy; Mattox, Tyler E.; Boyd, Michael R.; Piazza, Gary A. 分享 收藏
A novel PDE10/beta-catenin inhibitor, MCI-048, suppresses lung tumorigenesis to block metastasis Zhu, Bing; Ramirez-Alcantara, Veronica; Ward, Antonio; Berry, Kristy; Keeton, Adam B.; Boyd, Michael R.; Maxuitenko, Yulia; Chen, Xi; Piazza, Gary A. 分享 收藏
Characterization of a novel class of RAS inhibitory compounds with potent anti-tumor activity Ward, Antonio; Chen, Xi; Valiyaveettil, Jacob; Zhu, Bing; Ramirez-Alcantara, Veronica; Lee, Kevin J.; Lindsey, Ashley; Berry, Kristy; Mattox, Tyler E.; McConnell, Kate; Boyd, Michael R.; Piazza, Gary A.; Keeton, Adam B. 分享 收藏
DC070-547, a novel Ras inhibitor potently and selectivity inhibits colon tumor growth in vitro and in vivo Ramirez-Alcantara, Veronica; Keeton, Adam B.; Zhu, Bing; Lee, Kevin J.; Canzoneri, Joshua; Lindsey, Ashley S.; Barnes, Luciana Madeira da Silva; Berry, Kristy; Valiyaveettil, Jacob; Chen, Xi; Boyd, Michael R.; Piazza, Gary 分享 收藏
Discovery and in vitro and in vivo characterization of a novel, small-molecule Ras inhibitor class Keeton, Adam B.; Zhu, Bing; Lee, Kevin J.; Canzoneri, Joshua C.; Sigler, Sara C.; Lindsey, Ashley S.; Ramirez-Alcantara, Veronica; Barnes, Luciana; Mattox, Tyler E.; McConnell, Kate; Berry, Kristy L.; Valiyaveettil, Jacob; Chen, Xi; Boyd, Michael R.; Piazza, Gary A. 分享 收藏
A novel Ras inhibitor potently and selectively suppresses lung tumor cell growth by blocking Ras-Raf binding Zhu, Bing; Chen, Xi; Ramirez-Alcantara, Veronica; Lee, Kevin; Valiyaveettil, Jacob; Canzoneri, Joshua; Sigler, Sara; Berry, Kristy; Lindsey, Ashley; Keeton, Adam; Boyd, Michael R.; Piazza, Gary A. 分享 收藏
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A novel class of Ras selective inhibitors Canzoneri, Joshua C.; Chen, Xi; Keeton, Adam B.; Lee, Kevin; Gary, Bernard; Butler, Ethan B.; Grizzle, William E.; Wilson, Landon; Barnes, Stephen; Boyd, Michael R.; Piazza, Gary A. 分享 收藏
Validation of phosphodiesterase 10A as a cancer target Lee, Kevin; Li, Nan; Chen, Xi; Zhu, Bing; Yet, Larry; da Silva, Luciana Madeira; Russo, Suzanne; Keeton, Adam B.; Boyd, Michael R.; Piazza, Gary A. 分享 收藏
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Candidaspongiolides, distinctive analogues of tedanolide from sponges of the genus Candidaspongia Meragelman, Tamara L.; Willis, Richard H.; Woldemichael, Girma M.; Heaton, Andrew; Murphy, Peter T.; Snader, Kenneth M.; Newman, David J.; Van Soest, Rob; Boyd, Michael R.; Cardellina, John H., II; McKee, Tawnya C. 分享 收藏
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