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M

Matthew T. Eddy

university of florida

H指数:27

被引数:2,625

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Structural insight into the activation of adenosine A2AR/A2BR by the dual-agonist MRS3997

MRS3997作为双重激动剂对腺苷A2AR/A2BR活化的结构洞察

Communications Biology

IF5.1

2026-09-230

OA

An Integrative Biophysical and Computational Workflow Uncovers New Allosteric Sites and Modulators of the Human A2A Adenosine Receptor

整合生物物理与计算工作流程揭示人源A2A腺苷受体新的别构位点及调节剂

ACS Chemical Biology

IF3.8

2026-04-100

PRE

Solvent Reorganization in Stabilized Protein–Polymer Conjugates Visualized by Two-Dimensional Infrared and Nuclear Magnetic Resonance Spectroscopy

溶剂重组在稳定化蛋白质-聚合物缀合物中的可视化：二维红外和核磁共振光谱学研究

IF8.7

2026-02-250

OA

The influence of lipids and biological membranes on the conformational equilibria of GPCRs: Insights from NMR spectroscopy

脂质和生物膜对GPCRs构象平衡的影响：核磁共振光谱学的见解

Current Opinion in Structural Biology

IF7

2025-06-270

PRE

The Conformational Equilibria of a Human GPCR Compared between Lipid Vesicles and Aqueous Solutions by Integrative 19 F-NMR

通过整合19F-NMR比较脂质体和水溶液中的人体GPCR构象平衡

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2025-05-160

PRE

Development of an In Situ G Protein-Coupled Receptor Fragment Molecule Screening Approach with High-Resolution Magic Angle Spinning Nuclear Magnetic Resonance

ACS CHEMICAL BIOLOGY

IF3.8

2025-01-210

PRE

Interaction networks within disease-associated GaS variants characterized by an integrative biophysical approach

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2024-08-010

OAAI

Single-molecule visualization of human A2A adenosine receptor activation by a G protein and constitutively activating mutations

COMMUNICATIONS BIOLOGY

IF5.1

2023-11-305

OAAI

Illuminating GPCR signaling mechanisms by NMR spectroscopy with stable-isotope labeled receptors

CURRENT OPINION IN PHARMACOLOGY

IF4.2

2023-10-012

OAAI

Conserved Protein-Polymer Interactions across Structurally Diverse Polymers Underlie Alterations to Protein Thermal Unfolding

ACS CENTRAL SCIENCE

IF10.4

2023-03-144

OAAI

Anionic phospholipids control mechanisms of GPCR-G protein recognition

NATURE COMMUNICATIONS

IF15.7

2023-02-1328

OAAI

Global insights into the fine tuning of human A2AAR conformational dynamics in a ternary complex with an engineered G protein viewed by NMR

IF6.9

2022-12-014

OAAI

Atomic-Scale View of Protein-PEG Interactions that Redirect the Thermal Unfolding Pathway of PEGylated Human Galectin-3

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2022-08-254

OA

New Insights into the Structure-Function Relationships of G Proteins Containing Disease-Associated Mutations

IF4.2

2022-05-130

PRE

Structural Insights into Activation of a Human G Protein-Coupled Receptor by Membrane Phospholipids

IF4.2

2021-05-140

PRE

Structural biology of human GPCR drugs and endogenous ligands - insights from NMR spectroscopy

IF4.3

2020-08-014

OAAI

Adenosine A2Areceptor antagonists: from caffeine to selective non-xanthines

BRITISH JOURNAL OF PHARMACOLOGY

IF7.7

2020-06-1958

OAAI

Studying Structural Plasticity Underlying GPCR Function

BIOPHYSICAL JOURNAL

IF3.1

2019-02-010

OAAI

A2A adenosine receptor functional states characterized by 19F-NMR

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2018-11-2193

OAAI

GPCR drug discovery: integrating solution NMR data with crystal and cryo-EM structures

NATURE REVIEWS DRUG DISCOVERY

IF101.8

2018-11-09183

OAAI