Yao‐Chang Chen - Publications, H-index & Citations

Yao‐Chang Chen

National Defense Medical Center

50H指数

316论文数

1.2W被引数

收录论文 128

发表时间

Neuregulin 1β enhances pulmonary vein arrhythmogenesis by modulating electrophysiological characteristics, calcium and sodium homeostasis via the AKT/CaMKII pathway Neuregulin 1β通过调节电生理特性、钙和钠稳态，经由AKT/CaMKII通路增强肺静脉的致心律失常作用。

European Journal of Clinical Investigation

IF3.6

2025-06-02

PREAI

Yao-Chang Chen; Wei-Shiang Lin; Shih-Yu Huang; Yen-Yu Lu; Satoshi Higa; Shih-Ann Chen; Yi-Jen Chen

Phosphodiesterase 10A Inhibitor Modulates Right Ventricular Outflow Tract Electrophysiological Activities and Calcium Homeostasis via the cGMP/PKG Pathway 磷odiesterase 10A抑制剂通过cGMP/PKG通路调节右心室流出道电生理活动及钙离子稳态。

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

IF4.2

2025-03-11

OAAI

Lin, Feng-Zhi; Chen, Yao-Chang; Lin, Wei-Shiang; Lu, Yen-Yu

PCSK9 Enhances Cardiac Fibrogenesis via the Activation of Toll-like Receptor and NLRP3 Inflammasome Signaling PCSK9通过激活Toll样受体和NLRP3炎性小体信号通路增强心脏纤维化

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

IF4.9

2025-02-23

OAAI

Chung, Cheng-Chih; Kao, Yu-Hsun; Chen, Yao-Chang; Lin, Yung-Kuo; Higa, Satoshi; Hsu, Kai-Cheng; Chen, Yi-Jen

Indoxyl Sulfate Induces Ventricular Arrhythmias Attenuated by Secretoneurin in Right Ventricular Outflow Tract Cardiomyocytes

CARDIOVASCULAR TOXICOLOGY

IF3.7

2025-01-21

OAAI

Hung, Yuan; Cheng, Chen-Chuan; Lu, Yen-Yu; Huang, Shih-Yu; Chen, Yao-Chang; Lin, Fong-Jhih; Lin, Wei-Shiang; Kao, Yu-Hsun; Lin, Yung-Kuo; Chen, Shih-Ann; Chen, Yi-Jen

Impact of red-lime and white-lime betel quid on oral cell lines: Cytotoxicity and effects on fibronectin and type I collagen expression

JOURNAL OF DENTAL SCIENCES

IF3.1

2024-10-01

OAAI

Wu, Chia-Chen; Kao, Yu-Hsun; Kim, Yong-Deok; Ting, Chun-Chan; Chen, Hangshen; Wu, Feng-Cheng; Miura, Keiichiro; Ogasawara, Toru; Hoshi, Kazuto; Lo, Wen-liang; Chen, Yao-Chang; Jeng, Jiiang-Huei; Ko, Edward Chengchuan

Ibrutinib, a Bruton's tyrosine kinase inhibitor, regulates ventricular electromechanical activities and enhances arrhythmogenesis

EUROPEAN JOURNAL OF PHARMACOLOGY

IF4.7

2024-08-01

PREAI

Liu, Chih-Min; Lin, Fong-Jhih; Chhay, Chheng; Chen, Yao-Chang; Lin, Yung-Kuo; Lu, Yen -Yu; Chan, Chao -Shun; Higa, Satoshi; Chen, Shih-Ann; Chen, Yi-Jen

Interleukin-33/ST2 axis involvement in atrial remodeling and arrhythmogenesis

TRANSLATIONAL RESEARCH

IF5.9

2024-06-01

PREAI

Cheng, Tzu-Yu; Chen, Yao-Chang; Li, Shao-Jung; Lin, Fong-Jhih; Lu, Yen-Yu; Lee, Ting-, I; Lee, Ting-Wei; Higa, Satoshi; Kao, Yu-Hsun; Chen, Yi-Jen

Targeting NLRP3 signaling reduces myocarditis-induced arrhythmogenesis and cardiac remodeling

JOURNAL OF BIOMEDICAL SCIENCE

IF12.1

2024-04-22

OAAI

Chin, Chye-Gen; Chen, Yao-Chang; Lin, Fong-Jhih; Lin, Yung-Kuo; Lu, Yen-Yu; Cheng, Tzu-Yu; Chen, Shih-Ann; Chen, Yi-Jen

Empagliflozin suppressed cardiac fibrogenesis through sodium-hydrogen exchanger inhibition and modulation of the calcium homeostasis

CARDIOVASCULAR DIABETOLOGY

IF10.6

2023-02-06

OAAI

Chung, Cheng-Chih; Lin, Yung-Kuo; Chen, Yao-Chang; Kao, Yu-Hsun; Yeh, Yung-Hsin; Trang, Nguyen Ngoc; Chen, Yi-Jen

Modulation of post-pacing action potential duration and contractile responses on ventricular arrhythmogenesis in chloroquine-induced long QT syndrome

EUROPEAN JOURNAL OF PHARMACOLOGY

IF4.7

2023-02-01

PREAI

Liu, Chih-Min; Lin, Fong-Jhih; Chen, Yao-Chang; Lin, Yung-Kuo; Lu, Yen-Yu; Chan, Chao-Shun; Higa, Satoshi; Chen, Shih-Ann; Chen, Yi-Jen

Gender Difference in Lithium-Induced Sodium Current Dysregulation and Ventricular Arrhythmogenesis in Right Ventricular Outflow Tract Cardiomyocytes

BIOMEDICINES

IF3.9

2022-10-28

OAAI

Liu, Ching-Han; Chen, Yao-Chang; Lu, Yen-Yu; Lin, Yung-Kuo; Higa, Satoshi; Chen, Shih-Ann; Chen, Yi-Jen

Disturbed Cardiac Metabolism Triggers Atrial Arrhythmogenesis in Diabetes Mellitus: Energy Substrate Alternate as a Potential Therapeutic Intervention

CELLS

IF5.2

2022-09-18

OAAI

Lkhagva, Baigalmaa; Lee, Ting-Wei; Lin, Yung-Kuo; Chen, Yao-Chang; Chung, Cheng-Chih; Higa, Satoshi; Chen, Yi-Jen

Effect of macrophage migration inhibitory factor on pulmonary vein arrhythmogenesis through late sodium current

EUROPACE

IF7.4

2022-09-03

OAAI

Chin, Chye-Gen; Chen, Yao-Chang; Lin, Yung-Kuo; Lu, Yen-Yu; Cheng, Wan-Li; Chung, Cheng-Chih; Chen, Shih-Ann; Chen, Yi-Jen

Klotho Modulates Pro-Fibrotic Activities in Human Atrial Fibroblasts through Inhibition of Phospholipase C Signaling and Suppression of Store-Operated Calcium Entry

BIOMEDICINES

IF3.9

2022-07-01

OAAI

Hung, Yuan; Chung, Cheng-Chih; Chen, Yao-Chang; Kao, Yu-Hsun; Lin, Wei-Shiang; Chen, Shih-Ann; Chen, Yi-Jen

Galectin-3 enhances atrial remodelling and arrhythmogenesis through CD98 signalling

ACTA PHYSIOLOGICA

IF5.6

2022-01-17

PREAI

Cheng, Wan-Li; Chen, Yao-Chang; Li, Shao-Jung; Lee, Ting-, I; Lee, Ting-Wei; Higa, Satoshi; Chung, Cheng-Chih; Kao, Yu-Hsun; Chen, Shih-Ann; Chen, Yi-Jen

Regional Diversities in Fibrogenesis Weighed as a Key Determinant for Atrial Arrhythmogenesis

BIOMEDICINES

IF3.9

2021-12-14

OAAI

Chung, Cheng-Chih; Chin, Chye-Gen; Lin, Yung-Kuo; Chen, Yao-Chang; Cheng, Wan-Li; Yeh, Yung-Hsin; Kao, Yu-Hsun; Chen, Yi-Jen

Vascular endothelial growth factor modulates pulmonary vein arrhythmogenesis via vascular endothelial growth factor receptor 1/NOS pathway 血管内皮生长因子通过血管内皮生长因子受体1/NOS途径调节肺静脉心律失常

EUROPEAN JOURNAL OF PHARMACOLOGY

IF4.7

2021-11-01

PREAI

Chang, Jun-Hei; Cheng, Chen-Chuan; Lu, Yen-Yu; Chung, Cheng-Chih; Yeh, Yung-Hsin; Chen, Yao-Chang; Higa, Satoshi; Chen, Shih-Ann; Chen, Yi-Jen

Ceramide modulates electrophysiological characteristics and oxidative stress of pulmonary vein cardiomyocytes

EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

IF3.6

2021-10-25

PREAI

Huang, Shih-Yu; Lu, Yen-Yu; Lin, Yung-Kuo; Chen, Yao-Chang; Chen, Yi-Ann; Chung, Cheng-Chih; Lin, Wei-Shiang; Chen, Shih-Ann; Chen, Yi-Jen

Calcium Regulation on the Atrial Regional Difference of Collagen Production Activity in Atrial Fibrogenesis

BIOMEDICINES

IF3.9

2021-06-17

OAAI

Chung, Cheng-Chih; Lin, Yung-Kuo; Chen, Yao-Chang; Kao, Yu-Hsun; Yeh, Yung-Hsin; Chen, Yi-Jen

Effects of phosphodiesterase-1 inhibitor on pulmonary vein electrophysiology and arrhythmogenesis phosphodiesterase-1抑制剂对肺静脉电生理和心律失常发生的影响

EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

IF3.6

2021-05-18

PREAI

Yugo, Dony; Chen, Yao-Chang; Lin, Yung-Kuo; Liu, Chih Min; Huang, Jen Hung; Chen, Shih-Ann; Chen, Yi-Jen

研究方向