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J

John D. Isaacs

newcastle university - uk

88H指数
712论文数
2.7W被引数
收录论文 193
发表时间
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Immune reset and immune retune: approaching cure?免疫重置和免疫恢复: 接近治愈？
errNature Reviews Rheumatology
IF32.7
err2026-02-16
err0
PREAI
errJohn D. Isaacs
err分享
err收藏
Long-term outcomes of abatacept in individuals at risk of developing rheumatoid arthritis (ALTO): a randomised, double-blind, placebo-controlled trial
errThe Lancet Rheumatology
IF0
err2026-01-20
err0
errOAAI
errAndrew P Cope; Marianna Jasenecova; Joana C Vasconcelos; Sumera Qureshi; Karin A van Schie; Andrew Filer; Karim Raza; Maria Antonietta D’Agostino; Iain B McInnes; Stefan Siebert; John D Isaacs; Arthur G Pratt; Benjamin A Fisher; Christopher D Buckley; Paul Emery; Kulveer Mankia; Pauline Ho; Maya H Buch; Coziana Ciurtin; Dirkjan van Schaardenburg
err分享
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Rheumatoid arthritis and osteoarthritis patients demonstrate comparable rates of major adverse cardiovascular events: a single-centre retrospective cohort study类风湿关节炎和骨关节炎患者表现出相似的主要不良心血管事件发生率：一项单中心回顾性队列研究
errRheumatology Advances in Practice
IF2.1
err2026-01-01
err0
PREAI
errLin, Chung M. A.; Tabaqchali, Hadeel M.; White, Stephen; Pratt, Arthur G.; Isaacs, John D.; Cooles, Faye A. H.
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Patterns of steroid use in patients with established rheumatoid arthritis commencing treatment with biologic or targeted synthetic DMARDs类风湿关节炎患者使用生物制剂或靶向合成DMARDs治疗时的糖皮质激素使用模式
errRheumatology Advances in Practice
IF2.1
err2026-01-01
err0
errOAAI
errStadler, Michael; Bindra, Shae; Cheung, Annie; Yap, Chuan Fu; Bluett, James; Plant, Darren; Nair, Nisha; Hyrich, Kimme; Morgan, Ann; Wilson, Anthony G.; Isaacs, John D.; Barton, Anne
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Skeletal muscle effects of Janus kinase inhibition in rheumatoid arthritis (RAMUS): a single-arm, experimental medicine study类风湿关节炎中JAK激酶抑制对骨骼肌的影响（RAMUS）：一项单臂实验性药物研究
errThe Lancet Rheumatology
IF0
err2025-10-15
err0
errOAAI
errJoshua L Bennett; Kieren G Hollingsworth; Arthur G Pratt; Abbie E A Degnan; Gráinne S Gorman; Catherine Feeney; Najib Naamane; Jérémie Nsengimana; Avan A Sayer; Amy E Anderson; John D Isaacs
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Machine Learning Analysis of Whole-Blood Transcriptomics Data in Rheumatoid Arthritis Patients Treated with Adalimumab Identifies Predictive Biomarkers of Response类风湿关节炎患者接受阿达木单抗治疗后，全血转录组学数据的机器学习分析可识别出反应的预测生物标志物
errArthritis & Rheumatology
IF10.9
err2025-05-26
err0
errOAAI
errChuan Fu Yap; Nisha Nair; Ann W. Morgan; John D. Isaacs; Anthony G. Wilson; Kimme Hyrich; Guillermo Barturen; María Riva-Torrubia; Marta Gut; Ivo Gut; Marta E. Alarcón Riquelme; Anne Barton; Darren Plant
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Pre-treatment GlycA measurement provides no additional predictive utility beyond routine clinical measures in patients with rheumatoid arthritis治疗前GlycA测量在类风湿关节炎患者中，不提供超越常规临床指标的额外预测价值。
errRHEUMATOLOGY
IF4.4
err2025-05-13
err0
PREAI
errLing, Stephanie F.; Yap, Chuan Fu; Nair, Nisha; Verstappen, Suzanne M. M.; Morgan, Ann W.; Isaacs, John D.; Wilson, Anthony G.; Hyrich, Kimme L.; Barton, Anne
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The DESTINIES Study: an online Delphi study to build international consensus on the medical conditions and procedures that confer immunosuppression and their respective COVID-19 risk profilesDESTINIES研究：一项在线德尔菲研究，旨在就赋予免疫抑制的医疗条件和程序及其各自的COVID-19风险特征建立国际共识
errECLINICALMEDICINE
IF10
err2025-05-01
err0
errOAAI
errLeston, Meredith; Ordonez-Mena, Jose M.; Joy, Mark; Hobbs, F. D. Richard; de Lusignan, Simon; Teh, Benjamin W.; de Groot, Ingrid; McInnes, Iain; El Sahly, Hana M.; Isaacs, John; Andersson, Monique; Raffi, Francois; Lim, Wei Shen; Conway, Richard; Siebert, Stefan; Buchan, Iain; Underwood, Martin; Lowe, David; Hoerger, Michael; Griffiths, Christopher E. M.; Alunno, Alessia; Lee, Lennard Y. W.
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Patient-reported outcomes as early warning signals of flare following drug cessation in rheumatoid arthritis患者报告结局作为药物停用后类风湿关节炎复发的早期预警信号
errRHEUMATOLOGY
IF4.4
err2025-04-28
err0
PREAI
errGumber, Leher; Rayner, Fiona; Bigirumurame, Theophile; Dyke, Bernard; Melville, Andrew R.; Kerrigan, Sean; McGucken, Andrew; Naamane, Najib; Pritchard, Jonathan; Buckley, Christopher D.; Filer, Andrew; McInnes, Iain; Raza, Karim; Siebert, Stefan; Wason, James; Fai-Ng, Wan; Anderson, Amy E.; Isaacs, John D.; Baker, Kenneth F.; Pratt, Arthur G.
err分享
err收藏
Patient-reported outcomes as early warning signs of flare following drug cessation in rheumatoid arthritis患者报告结局作为药物停用后类风湿关节炎复发的早期预警信号
errRMD OPEN
IF4.7
err2025-04-01
err0
errOAAI
errGumber, Leher; Rayner, Fiona; Bigirumurame, Theophile; Dyke, Bernard; Melville, Andrew; Kerrigan, Sean; McGucken, Andrew; Naamane, Najib; Prichard, Jonathan; Buckley, Christopher D.; Filer, Andrew; McInnes, Iain B.; Raza, Karim; Siebert, Stefan; Wason, James M. S.; Ng, Wan-Fai; Anderson, Amy E.; Isaacs, John D.; Baker, Kenneth F.; Pratt, Arthur G.
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Bruton's tyrosine kinase - A new target for immune mediated inflammatory diseases?布鲁顿酪氨酸激酶——免疫介导性炎症疾病的新靶点？
errSEMINARS IN ARTHRITIS AND RHEUMATISM
IF4.4
err2025-02-01
err0
errOAAI
errIsaacs, J
err分享
err收藏
A phase 1 experimental medicine study of anti-CD3 monoclonal antibody in rheumatoid arthritis
errIMMUNOTHERAPY ADVANCES
IF4.9
err2025-01-01
err0
errOAAI
errLawson, Catherine A.; Harry, Rachel; Griffiths, Bridget; Hale, Geoff; Waldmann, Herman; Isaacs, John D.
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Deep phenotyping of T regulatory cells in psoriatic arthritis highlights targetable mechanisms of disease
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2025-01-01
err0
PREAI
errMctaggart, Tegan; Lim, Jing Xuan; Smith, Katie J.; Heaney, Bronagh; Mcdonald, David; Hulme, Gillian; Hussain, Rafiqul; Coxhead, Jonathan; Degnan, Abbie E. A.; Isaacs, John; Pratt, Arthur; Amarnath, Shoba
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Monitoring immunE DysregulAtion foLLowing Immune checkpOint-inhibitioN (MEDALLION): protocol for an observational cancer immunotherapy cohort study监测免疫检查点抑制后的免疫失调 (MEDALLION): 观察性癌症免疫疗法队列研究的方案
errBMC CANCER
IF3.4
err2024-06-14
err1
errOAAI
errGault, Abigail; Hogarth, Linda; Williams, Kristian C.; Greystoke, Alastair; Rajan, Neil; Speight, Ally; Lamb, Christopher A.; Bridgewood, Alison; Brown-Schofield, Lisa-Jayne; Rayner, Fiona; Isaacs, John D.; Nsengimana, Jeremie; Stewart, Christopher J.; Anderson, Amy E.; Plummer, Ruth; Pratt, Arthur G.
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DISSECTING EARLY RA PATIENT TRAJECTORIES THROUGH TIME-INDEPENDENT DISEASE STATE IDENTIFICATION IDENTIFIES DISTINCT PATTERNS DISSECTED BY INFLAMMATION IN BLOOD OR JOINTS通过非时间依赖性疾病状态识别来剖析早期类风湿关节炎患者的病程，可识别出受血液或关节炎症影响的独特模式
errANNALS OF THE RHEUMATIC DISEASES
IF20.6
err2024-06-01
err0
PREAI
errSteinz, N.; Maarseveen, T. D.; Cope, A.; Isaacs, J.; Winkler, A.; Huizinga, T.; Yann, A.; Knevel, R.
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QUIESCENT HUMAN BLOOD MONOCYTE STATES ARE PRE-COMMITTED TO AN INFLAMMATORY SYNOVIAL TRANSCRIPTIONAL PROGRAM静息状态的人体单核细胞状态是预先决定于炎症滑膜的转录程序
errANNALS OF THE RHEUMATIC DISEASES
IF20.6
err2024-06-01
err0
PREAI
errAmies, E.; Christofi, M.; Mulhearn, B.; Marshall, L.; Sutcliffe, M.; Hyrich, K.; Morgan, A.; Wilson, A. G.; Isaacs, J.; Plant, D.; Barton, A.; Hussell, T.; Raychaudhuri, S.; Martin, P.; Viatte, S.
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HEALTHY AND PATHOLOGIC T-CELL AUTOREACTIVITY IN RA健康与病理T细胞自身反应性在RA
errANNALS OF THE RHEUMATIC DISEASES
IF20.6
err2024-06-01
err0
PREAI
errStanway, J.; Anderson, A. E.; Pratt, A.; Isaacs, J.
err分享
err收藏
Population Pharmacokinetic Analysis and Simulation of Alternative Dosing Regimens for Biosimilars to Adalimumab and Etanercept in Patients with Rheumatoid Arthritis
errPHARMACEUTICS
IF5.5
err2024-05-23
err0
errOAAI
errLing, Stephanie F.; Ogungbenro, Kayode; Darwich, Adam S.; Ariff, Amirah Binti Mohammad; Nair, Nisha; Bluett, James; Morgan, Ann W.; Isaacs, John D.; Wilson, Anthony G.; Hyrich, Kimme L.; Barton, Anne; Plant, Darren
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Abatacept in individuals at high risk of rheumatoid arthritis (APIPPRA): a randomised, double-blind, multicentre, parallel, placebo-controlled, phase 2b clinical trialAbatacept治疗类风湿关节炎高危人群 (APIPPRA): 一项随机、双盲、多中心、平行、安慰剂对照、2b期临床试验
errLANCET
IF88.5
err2024-03-01
err34
errOAAI
errCope, Andrew P.; Jasenecova, Marianna; Vasconcelos, Joana C.; Filer, Andrew; Raza, Karim; Qureshi, Sumera; D'Agostino, Maria Antonietta; Mcinnes, Iain B.; Isaacs, John; Pratt, Arthur G.; Fisher, Benjamin A.; Buckley, Christopher; Emery, Paul; Ho, Pauline; Buch, Maya H.; Ciurtin, Coziana; van Schaardenburg, Dirkjan; Huizinga, Thomas; Toes, Rene; Georgiou, Evangelos; Kelly, Joanna; Murphy, Caroline; Prevost, A. Toby
err分享
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CAR T Cells - A New Horizon for Autoimmunity?
errNEW ENGLAND JOURNAL OF MEDICINE
IF78.5
err2024-02-22
err3
PREAI
errIsaacs, John D.
err分享
err收藏

研究方向

暂无研究方向
合作学者
合作期刊
J
Johann S. de Bono
H 指数: 160 · 论文数: 2.5K
P
Paul Emery
H 指数: 158 · 论文数: 1.6K
D
Désirée van der Heijde
H 指数: 158 · 论文数: 1.3K
I
Iain B. McInnes
H 指数: 144 · 论文数: 1.3K
T
T. Huizinga
H 指数: 140 · 论文数: 2.0K
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