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C

Chang‐Mei Liu

chinese academy of sciences

28H指数
153论文数
3.2K被引数
收录论文 80
发表时间
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Histone modifications and chromatin landscapes in microglial function: Developmental imprinting and disease-associated reprogramming组蛋白修饰和染色质景观在小胶质细胞功能中的作用：发育印记和疾病相关重编程
errAgeing Research Reviews
IF12.4
err2026-09-18
err0
PREAI
errXiao Li; Rong-Liang Guo; Zhao-Qian Teng; Pei-Pei Liu; Chang-Mei Liu
err分享
err收藏
Targeting FBXO48 with BC1618 promotes axon regeneration and alleviates symptoms of Parkinson’s disease靶向FBXO48的BC1618促进轴突再生并缓解帕金森病症状
errJournal of Advanced Research
IF13
err2026-07-25
err0
errOAAI
errYong-Quan Sun; Pei-Pei Liu; Chang-Ping Li; Zhen-Gang Liu; Lai-Yang Zhou; Ning-Li Wang; Feng-Quan Zhou; Zhao-Qian Teng; Chang-Mei Liu
err分享
err收藏
Loss of Echs1 in neural stem and progenitor cells impairs neurogenesis via ER stress activation and lipid metabolic reprogramming神经干细胞和祖细胞中Echs1的缺失通过内质网应激激活和脂质代谢重编程损害神经发生
errNature Communications
IF15.7
err2026-07-01
err0
errOAAI
errChun-Hui Duan; Pei-Pei Liu; Xin Sun; Wen-Hui Ma; Jia-Ying Pang; Zi-Han Zhang; Xiao Li; Lin-Fei Jiao; Hong-Zhen Du; Zhao-Qian Teng; Hou-Zao Chen; Chang-Mei Liu
err分享
err收藏
Targeting OTUD7A-HINT1 deubiquitination activates mTOR signaling for CNS regeneration靶向OTUD7A-HINT1去泛素化激活mTOR信号通路以促进中枢神经系统再生
errCell Death & Disease
IF9.6
err2026-06-20
err0
errOAAI
errZhen-Gang Liu; Yong-Quan Sun; Lai-Yang Zhou; Ze-Yu Liu; Ling-Wei Zhao; Feng-Quan Zhou; Bo-Yin Zhang; Chang-Mei Liu
err分享
err收藏
Photoenzymatic catalysis enables enantioselective radical dearomative spirocyclization光酶催化实现了对映选择性自由基去芳构化螺环化反应
errNature Communications
IF15.7
err2025-12-23
err0
errOAAI
errChangtong Zhu; Yan Zhang; Zhiwei Deng; Luyun Ji; Xiaorui Chen; Dejing Yin; Changmei Liu; Zhengshan Luo; Yijian Rao; Zhenbo Yuan
err分享
err收藏
Engineering C-glycosyltransferase UGT708A60 to enhance the activity and thermostability for the highly efficient biosynthesis of nothofagin通过改造C-糖基转移酶UGT708A60来增强其活性和热稳定性，以实现高效率地生物合成异鼠李素。
errFood Bioscience
IF5.9
err2025-11-17
err0
PREAI
errGuangyao Li; Weilun Zhang; Zhiwei Deng; Changmei Liu; Zhengshan Luo; Yan Zhang; Zhenbo Yuan; Yijian Rao
err分享
err收藏
Design an artificially concise biocatalytic cascade for the manufacture of Rebaudioside M from a naturally derived steviol glycosides mixture设计一种人工合成的生物催化级联反应，用于从天然来源的甜菊糖苷混合物中制备Rebaudioside M。
errGreen Chem.
IF9.2
err2025-11-07
err0
PREAI
errZhengshan Luo; Xupeng Guo; Zhiwei Deng; Dong Guo; Yan Zhang; Changmei Liu; Zhenbo Yuan; Yijian Rao
err分享
err收藏
Structure-guided engineering of glycosyltransferase UGT94B1 coupled with UDP-glucose regeneration enables highly efficient biosynthesis of rebaudioside D结构导向的糖基转移酶UGT94B1工程改造与UDP-葡萄糖再生相结合，实现了甜菊糖苷D的高效生物合成
errMolecular Catalysis
IF4.9
err2025-11-02
err0
PREAI
errZhengshan Luo; Xupeng Guo; Zhiwei Deng; Lingang Song; Dong Guo; Yan Zhang; Changmei Liu; Zhenbo Yuan; Yijian Rao
err分享
err收藏
A Modular Chemoenzymatic Cascade Simplifies Divergent Synthesis of Natural and Unnatural Benzylisoquinoline Alkaloids一种模块化化学酶级联简化了天然和非天然苄基异喹啉类生物碱的多样化合成
errAdvanced Science
IF14.1
err2025-10-20
err0
errOAAI
errHuiling Liu; Zhenbo Yuan; Yue Gao; Fei Li; Zhiwei Deng; Yan Zhang; Zhengshan Luo; Changmei Liu; Yijian Rao
err分享
err收藏
Improving the thermostability of glycosyltransferase UGT94E13 by rational design for highly efficient biosynthesis of rebaudioside M8通过理性设计提高糖基转移酶UGT94E13的热稳定性，以实现甜菊苷M8的高效生物合成
errFood Bioscience
IF5.9
err2025-09-29
err0
PREAI
errHua Jiang; Guangyao Li; Weilun Zhang; Zhiwei Deng; Mengliang Yang; Changmei Liu; Zhengshan Luo; Yan Zhang; Yijian Rao; Zhenbo Yuan
err分享
err收藏
Improving the catalytic activity of glycosyltransferase UGT88F1 for highly efficient biosynthesis of phlorizin through structure-guided engineering通过结构导向工程提高糖基转移酶UGT88F1的催化活性，以实现高效率地生物合成木酚素葡萄糖苷。
errFood Bioscience
IF5.9
err2025-09-16
err0
PREAI
errXupeng Guo; Zhiwei Deng; Yizhe Yang; Baoxu Zhang; Yan Zhang; Zhenbo Yuan; Changmei Liu; Yijian Rao; Zhengshan Luo
err分享
err收藏
Preserving blood-retinal barrier integrity: a path to retinal ganglion cell protection in glaucoma and traumatic optic neuropathy
errCELL REGENERATION
IF4.7
err2025-04-02
err0
errOAAI
errZhou, Lai-Yang; Liu, Zhen-Gang; Sun, Yong-Quan; Li, Yan-Zhong; Teng, Zhao-Qian; Liu, Chang-Mei
err分享
err收藏
Modular Chemoenzymatic Cascade for Highly Diastereo- and Enantioselective Synthesis of 1,3-Disubstituted Tetrahydroisoquinolines模块化化学生物酶级联反应用于高效非对映选择性和对映选择性合成1,3-二取代四氢异喹啉类化合物
errACS CATALYSIS
IF13.1
err2025-03-19
err0
PREAI
errZhang, HH; Zhang, Y; Zhu, CT; Deng, ZW; Ji, LY; Yin, DJ; Liu, CM; Luo, ZS; Yuan, ZB; Rao, YJ
err分享
err收藏
Roles of Kdm6a and Kdm6b in Regulation of Mammalian Neural RegenerationKdm6a和Kdm6b在哺乳动物神经再生调控中的作用
errADVANCED SCIENCE
IF0
err2025-02-14
err1
errOAAI
errYang, SG; Li, CP; Wang, XW; Huang, T; Qian, C; Li, Q; Zhao, LR; Zhou, SY; Ding, CY; Nie, R; Saijilafu; Hong, YC; Liu, CM; Zhou, FQ
err分享
err收藏
Highly Efficient Biosynthesis of Rebaudioside M9 through Enzyme Screening and Structure-Guided Engineering通过酶筛选和结构引导工程高效合成莱鲍迪苷M9
errJOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
IF6.2
err2025-01-30
err0
PREAI
errGuo, Xupeng; Zhang, Yan; Deng, Zhiwei; Chen, Yilin; Yuan, Zhenbo; Liu, Changmei; Rao, Yijian; Luo, Zhengshan
err分享
err收藏
Marcks overexpression in retinal ganglion cells promotes optic nerve regeneration
errCELL DEATH & DISEASE
IF9.6
err2024-12-18
err0
errOAAI
errPeng, Xue-Qi; Li, Yan-Zhong; Gu, Chen; He, Xuan-Cheng; Li, Chang-Ping; Sun, Yong-Quan; Du, Hong-Zhen; Teng, Zhao-Qian; Liu, Chang-Mei
err分享
err收藏
An EED/PRC2-H19 Loop Regulates Cerebellar Development
errADVANCED SCIENCE
IF14.1
err2024-11-05
err0
errOAAI
errLiu, Pei-Pei; Han, Xiao; Li, Xiao; Dai, Shang-Kun; Xu, Ya-Jie; Jiao, Lin-Fei; Du, Hong-Zhen; Zhao, Li-Hua; Li, Rong-Feng; Teng, Zhao-Qian; Yang, Yun-Gui; Liu, Chang-Mei
err分享
err收藏
MARK2 variants cause autism spectrum disorder via the downregulation of WNT/b-catenin signaling pathway
errAMERICAN JOURNAL OF HUMAN GENETICS
IF8.1
err2024-11-01
err1
errOAAI
errGong, Maolei; Li, Jiayi; Qin, Zailong; Wilke, Matheus Vernet Machado Bressan; Liu, Yijun; Li, Qian; Liu, Haoran; Liang, Chen; Morales-Rosado, Joel A.; Cohen, Ana S. A.; Hughes, Susan S.; Sullivan, Bonnie R.; Waddell, Valerie; van den Boogaard, Marie-Jose H.; van Jaarsveld, Richard H.; van Binsbergen, Ellen; van Gassen, Koen L.; Wang, Tianyun; Hiatt, Susan M.; Amaral, Michelle D.; Kelley, Whitley, V; Zhao, Jianbo; Feng, Weixing; Ren, Changhong; Yu, Yazhen; Boczek, Nicole J.; Ferber, Matthew J.; Lahner, Carrie; Elliott, Sherr; Ruan, Yiyan; Mignot, Cyril; Keren, Boris; Xie, Hua; Wang, Xiaoyan; Popp, Bernt; Zweier, Christiane; Piard, Juliette; Coubes, Christine; Mau-Them, Frederic Tran; Safraou, Hana; Innes, A. Micheil; Gauthier, Julie; Michaud, Jacques L.; Koboldt, Daniel C.; Sylvie, Odent; Willems, Marjolaine; Tan, Wen-Hann; Cogne, Benjamin; Rieubland, Claudine; Braun, Dominique; Mclean, Scott Douglas; Platzer, Konrad; Zacher, Pia; Oppermann, Henry; Evenepoel, Lucie; Blanc, Pierre; El Khattabi, Laila; Haque, Neshatul; Dsouza, Nikita R.; Zimmermann, Michael T.; Urrutia, Raul; Klee, Eric W.; Shen, Yiping; Du, Hongzhen; Rappaport, Leonard; Liu, Chang-Mei; Chen, Xiaoli
err分享
err收藏
Loss of microglial Arid1a exacerbates microglial scar formation via elevated CCL5 after traumatic brain injury
errCELL COMMUNICATION AND SIGNALING
IF8.9
err2024-09-30
err0
errOAAI
errKe, Jin-Peng; He, Bao-Dong; Gong, Mao-Lei; Yan, Zhong-Ze; Du, Hong-Zhen; Teng, Zhao-Qian; Liu, Chang-Mei
err分享
err收藏
Lhx2 promotes axon regeneration of adult retinal ganglion cells and rescues neurodegeneration in mouse models of glaucoma
errCELL REPORTS MEDICINE
IF10.6
err2024-05-01
err0
errOAAI
errLi, Chang -Ping; Wu, Shen; Sun, Yong-Quan; Peng, Xue-Qi; Gong, Maolei; Du, Hong-Zhen; Zhang, Jingxue; Teng, Zhao-Qian; Wang, Ningli; Liu, Chang-Mei
err分享
err收藏

研究方向

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合作学者
合作期刊
F
Fred H. Gage
H 指数: 219 · 论文数: 1.1K
黄
黄威 (Wei Huang)
H 指数: 217 · 论文数: 6.0K
李红 封面图
李红 (Hong Li)
H 指数: 153 · 论文数: 2.0K
王
王剑 (Jian Wang)
H 指数: 100 · 论文数: 1.8K
刘
刘丹 (Dan Liu)
H 指数: 89 · 论文数: 1.9K
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