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R

Rosemary J. Akhurst

University of California System
H指数:54
被引数:1.5万

个人简介

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Integrin αvβ8 on T cells suppresses anti-tumor immunity in multiple models and is a promising target for tumor immunotherapy
CELL REPORTS
IF6.9
2021-07-0137
OAAI
Dodagatta-Marri, Eswari; Ma, Hsiao-Yen; Liang, Benjia; Li, John; Meyer, Dominique S.; Chen, Szu-Ying; Sun, Kai-Hui; Ren, Xin; Zivak, Bahar; Rosenblum, Michael D.; Headley, Mark B.; Pinzas, Lauren; Reed, Nilgun, I; Del Cid, Joselyn S.; Hann, Byron C.; Yang, Sharon; Giddabasappa, Anand; Noorbehesht, Kavon; Yang, Bing; Dal Porto, Joseph; Tsukui, Tatsuya; Niessen, Kyle; Atakilit, Amha; Akhurst, Rosemary J.; Sheppard, Dean
α-PD-1 therapy elevates Treg/Th balance and increases tumor cell pSmad3 that are both targeted by -TGF antibody to promote durable rejection and immunity in squamous cell carcinomas

Α-pd-1治疗可提高Treg/Th平衡并增加肿瘤细胞pSmad3，这两者均被-TGF抗体靶向，以促进鳞状细胞癌的持久排斥和免疫力

JOURNAL FOR IMMUNOTHERAPY OF CANCER
IF10.6
2019-03-04144
OAAI
Dodagatta-Marri, E.; Meyer, D. S.; Reeves, M. Q.; Paniagua, R.; To, M. D.; Binnewies, M.; Broz, M. L.; Mori, H.; Wu, D.; Adoumie, M.; Del Rosario, R.; Li, O.; Buchmann, T.; Liang, B.; Malato, J.; Arce Vargus, F.; Sheppard, D.; Hann, B. C.; Mirza, A.; Quezada, S. A.; Rosenblum, M. D.; Krummel, M. F.; Balmain, A.; Akhurst, R. J.
Genetic variants of Adam17 differentially regulate TGFβ signaling to modify vascular pathology in mice and humans
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2014-05-0841
OAAI
Kawasaki, Kyoko; Freimuth, Julia; Meyer, Dominique S.; Lee, Marie M.; Tochimoto-Okamoto, Akiko; Benzinou, Michael; Clermont, Frederic F.; Wu, Gloria; Roy, Ritu; Letteboer, Tom G. W.; van Amstel, Johannes Kristian Ploos; Giraud, Sophie; Dupuis-Girod, Sophie; Lesca, Gaeten; Westermann, Cornelius J. J.; Coffey, Robert J., Jr.; Akhurst, Rosemary J.
Mouse and human strategies identify PTPN14 as a modifier of angiogenesis and hereditary haemorrhagic telangiectasia (vol 3, pg 616, 2012)
NATURE COMMUNICATIONS
IF15.7
2012-10-230
OAAI
Benzinou, Michael; Clermont, Frederic F.; Letteboer, Tom G. W.; Kim, Jai-Hyun; Espejel, Silvia; Harradine, Kelly A.; Arbelaez, Juan; Luu, Minh Thu; Roy, Ritu; Quigley, David; Higgins, Mamie Nakayama; Zaid, Musa; Aouizerat, Bradley E.; van Amstel, Johannes Kristian Ploos; Giraud, Sophie; Dupuis-Girod, Sophie; Lesca, Gaetan; Plauchu, Henri; Hughes, Christopher C. W.; Westermann, Cornelius J. J.; Akhurst, Rosemary J.
Mouse and human strategies identify PTPN14 as a modifier of angiogenesis and hereditary haemorrhagic telangiectasia
NATURE COMMUNICATIONS
IF15.7
2012-01-1056
OAAI
Benzinou, Michael; Clermont, Frederic F.; Letteboer, Tom G. W.; Kim, Jai-hyun; Espejel, Silvia; Harradine, Kelly A.; Arbelaez, Juan; Minh Thu Luu; Roy, Ritu; Quigley, David; Higgins, Mamie Nakayama; Zaid, Musa; Aouizerat, Bradley E.; van Amstel, Johannes Kristian Ploos; Giraud, Sophie; Dupuis-Girod, Sophie; Lesca, Gaetan; Plauchu, Henri; Hughes, Christopher C. W.; Westermann, Cornelius J. J.; Akhurst, Rosemary J.

研究方向

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R
Rik Derynck
H 指数:126论文数:252被引数:7.1万
A
Allan Balmain
H 指数:73论文数:332被引数:2.4万
F
Frederic F. Clermont
H 指数:10论文数:21被引数:496
D
Dominique S. Meyer
H 指数:19论文数:65被引数:1,464
D
David A. Quigley
H 指数:40论文数:441被引数:5,998
D
Dean Sheppard
H 指数:114论文数:494被引数:4.5万
E
Elise F. Saunier
H 指数:15论文数:47被引数:1,275
M
Minh Thu Luu
H 指数:4论文数:17被引数:181
S
Sophie Dupuis‐Girod
H 指数:46论文数:201被引数:9,600
R
Ritu Roy
H 指数:35论文数:206被引数:5,334