Wayne W. Hancock - Publications, H-index & Citations

Wayne W. Hancock

University of Pennsylvania

104H指数

609论文数

3.7W被引数

收录论文 255

发表时间

Differential effects of HDAC8 targeting on Foxp3+Tregs and effector T cells promote antitumor immunity HDAC8靶向对Foxp3+Tregs和效应T细胞的差异性影响促进抗肿瘤免疫

JCI Insight

IF6.1

2026-02-09

OAAI

Kong, Fanhua; Xiong, Van; Wang, Liqing; Han, Rongxiang; Fazelinia, Hossein; Roof, Jennifer; Spruce, Lynn; Beeler, Aaron B.; Hancock, Wayne W.

CAR T cells targeting CCR4 selectively deplete human Tregs ex vivo and in vivo 靶向CCR4的CAR T细胞在体外和体内选择性耗竭人Tregs

Blood Advances

IF7.1

2026-02-01

PREAI

Tilsed, Caitlin M.; Fong, Karen P.; Shi, Xinyi; Akimova, Tatiana; Wang, Liqing; Noguera-Ortega, Estela; Krouse, Ryan; Bermudez, Andres; Singhal, Sunil; Young, Regina; Eruslanov, Evgeniy; Watanabe, Keisuke; Hancock, Wayne W.; June, Carl H.; Albelda, Steven M.

Class IIa HDACs forced degradation allows resensitization of oxaliplatin-resistant FBXW7-mutated colorectal cancer IIa类HDACs的强制降解可使奥沙利铂耐药的FBXW7突变结直肠癌重新敏感化

Molecular Oncology

IF4.5

2025-10-31

OAAI

Vanessa Tolotto; Nicolò Gualandi; Ylenia Cortolezzis; Raffaella Picco; Monica Colitti; Francesca D'Este; Mariachiara Gani; Wayne W. Hancock; Giovanni Terrosu; Cristina Degrassi; Francesca Agostini; Claudio Brancolini; Luigi E. Xodo; Eros Di Giorgio

#1035 Differential impacts of APRIL and APRIL/BAFF inhibition on immune populations: implications for IgAN treatment and protective immunity #1035 APRIL和APRIL/BAFF抑制对免疫细胞群体的差异化影响：对IgAN治疗和保护性免疫的启示

Nephrology Dialysis Transplantation

IF5.6

2025-10-21

OAAI

Kirk J Rowley; Vinay Singh; Anna Roberts; Katherine A Heang; Prashanna Balaji Venkatasubramanian; Jacob Vinay Konakondla; Daved Fared; Michelle Lu; Brett Hurst; Wayne W Hancock; Gregory J Babcock; Luke N Robinson

MEF2D regulates T-cell function via CD70-CD27 signaling and promotes immune evasion in hepatocellular carcinoma MEF2D通过CD70-CD27信号通路调节T细胞功能，并促进肝细胞癌的免疫逃逸。

JOURNAL OF IMMUNOLOGY

IF3.4

2025-09-01

PREAI

Kong, Fanhua; Wang, Liqing; Lu, Zhongshan; Zhou, Jiakang; Ye, Qifa; Hancock, Wayne W.; Xiong, Yan

New Approaches to Old Techniques in Cell Handling for Microscopy 细胞显微术中细胞处理旧技术的创新方法

Cells 2025, Vol. 14, Page 1271

IF5.2

2025-08-26

PREAI

Zhanna Bartosh; Veenu Aishwarya; Wayne W. Hancock; Tatiana Akimova

Mitochondrial DNA lineages determine tumor progression through T cell reactive oxygen signaling 线粒体DNA谱系通过T细胞反应性氧信号调控肿瘤进展

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2025-01-03

OAAI

Yardeni, Tal; Olali, Arnold Z.; Chen, Hsiao-Wen; Wang, Liqing; Halton, Jeffrey A.; Zenab, Angi; Morrow, Ryan; Butic, Arrienne; Murdock, Deborah G.; Waymire, Katrina G.; Macgregor, Grant R.; Boursi, Ben; Beier, Ulf H.; Hancock, Wayne W.; Wallace, Douglas C.

Differential Effects of HDAC6 Inhibition Versus Knockout During Hepatic Ischemia-Reperfusion Injury Highlight Importance of HDAC6 C-terminal Zinc-finger Ubiquitin-binding Domain

TRANSPLANTATION

IF5

2024-09-24

PREAI

Concors, Seth J.; Hernandez, Paul T.; OBrien, Ciaran; DePaolo, John; Murken, Douglas R.; Aufhauser, David D.; Wang, Zhonglin; Xiong, Yan; Krumeich, Lauren; Ge, Guanghui; Beier, Ulf H.; Bhatti, Tricia R.; Kozikowski, Alan P.; Avelar, Leandro A. Alves; Kurz, Thomas; Hancock, Wayne W.; Levine, Matthew H.

Antisense targeting of FOXP3+Tregs to boost anti-tumor immunity

FRONTIERS IN IMMUNOLOGY

IF5.9

2024-08-21

OAAI

Akimova, Tatiana; Wang, Liqing; Bartosh, Zhanna; Christensen, Lanette M.; Eruslanov, Evgeniy; Singhal, Sunil; Aishwarya, Veenu; Hancock, Wayne W.

T-regulatory cells require Sin3a for stable expression of Foxp3 调节性T细胞需要Sin3a才能稳定表达Foxp3

FRONTIERS IN IMMUNOLOGY

IF5.9

2024-08-02

OAAI

Christensen, Lanette M.; Akimova, Tatiana; Wang, Liqing; Han, Rongxiang; Samanta, Arabinda; Di Giorgio, Eros; Hancock, Wayne W.

Foxp3 depends on Ikaros for control of regulatory T cell gene expression and function Foxp3依赖Ikaros控制调节性T细胞基因的表达和功能

ELIFE

IF0

2024-04-24

OAAI

Thomas, Rajan M.; Pahl, Matthew C.; Wang, Liqing; Grant, Struan F. A.; Hancock, Wayne W.; Wells, Andrew D.

MEF2D regulates T cell function via the CD70-CD27 signaling axis and promotes immune escape in hepatocellular carcinomas

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Kong, Fanhua; Wang, Liqing; Ye, Qifa; Xiong, Yan; Hancock, Wayne W.

HDAC8 targeting impairs Foxp3+Treg cell function and promotes antitumor immunity

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Kong, Fanhua; Wang, Liqing; Beeler, Aaron; Hancock, Wayne W.

Targeting CD4+FOXP3+Tregs to enhance anti-tumor immunity

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Akimova, Tatiana; Wang, Liqing; Bartosh, Zhanna; Eruslanov, Evgeniy; Albelda, Steven; Singhal, Sunil; Aishwarya, Veenu; Hancock, Wayne W.

Unexpected role of the NuRD component, Chd4, in Foxp3+Treg cells and its relevance to tumor immunotherapy

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Hancock, Wayne W.; Wang, Liqing; Minisini, Martina; di Giorgio, Eros; Babic, Ivan; Nurmemmedov, Elmar

FOXP3+regulatory T cells are associated with the severity and prognosis of sarcoidosis FOXP3调节性T细胞与结节病的严重程度和预后有关

FRONTIERS IN IMMUNOLOGY

IF5.9

2023-12-20

OAAI

Patterson, Karen C.; Miller, Wallace T.; Hancock, Wayne W.; Akimova, Tatiana

Methyl-CpG binding domain 2 (Mbd2) is an epigenetic regulator of autism-risk genes and cognition 甲基-CpG结合域2 (Mbd2) 是自闭症风险基因和认知的表观遗传调节剂

TRANSLATIONAL PSYCHIATRY

IF6.2

2023-07-13

OAAI

Lax, Elad; Do Carmo, Sonia; Enuka, Yehoshua; Sapozhnikov, Daniel M.; Welikovitch, Lindsay A.; Mahmood, Niaz; Rabbani, Shafaat A.; Wang, Liqing; Britt, Jonathan P.; Hancock, Wayne W.; Yarden, Yosef; Szyf, Moshe

Sin3A Controls FoxP3+Treg Production, Stability and Function

JOURNAL OF IMMUNOLOGY

IF3.4

2023-05-01

OAAI

Christensen, Lanette M.; Akimova, Tatiana; Han, Rongxaing; Wang, Liqing; Samanta, Arabinda; Hancock, Wayne W.

Sirtuin-1 Targeting Promotes Foxp3+ T-Regulatory Cell Function and Prolongs Allograft Survival

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-20

185

OAAI

Beier, Ulf H.; Wang, Liqing; Bhatti, Tricia R.; Liu, Yujie; Han, Rongxiang; Ge, Guanghui; Hancock, Wayne W.

Histone Deacetylase 6 and Heat Shock Protein 90 Control the Functions of Foxp3+ T-Regulatory Cells

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-20

249

OAAI

de Zoeten, Edwin F.; Wang, Liqing; Butler, Kyle; Beier, Ulf H.; Akimova, Tatiana; Sai, Hong; Bradner, James E.; Mazitschek, Ralph; Kozikowski, Alan P.; Matthias, Patrick; Hancock, Wayne W.

研究方向