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S

Steven Grant

Virginia Commonwealth University

H指数:89

被引数:3.5万

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Leveraging venetoclax-induced autophagy to enhance AUTAC-mediated Mcl1 degradation and overcome resistance in acute myeloid leukaemia

利用维奈克拉诱导的自噬来增强AUTAC介导的Mcl1降解并克服急性髓系白血病中的耐药性

British Journal of Haematology

IF3.8

2026-09-060

OAAI

Generation and preclinical assessment of depemokimab, an enhanced IL-5 antagonist monoclonal antibody

depemokimab的生成及临床前评估，depemokimab是一种增强型IL-5拮抗剂单克隆抗体。

IF3.6

2025-11-290

OAAI

Hypochlorous Acid-Gated Hydrolysis of a Phosphinate Ester Dye in Living Cells

次氯酸调控的磷亚酸酯染料在活细胞中的水解

Journal of the American Chemical Society

IF15.6

2025-10-220

OAAI

Geranylgeranyl transferase-1 inhibitor GGTI-2417 enhances the anti-tumour efficacy of histone deacetylase inhibitors in different T-cell lymphoma lines

法尼基转移酶-1抑制剂GGTI-2417增强组蛋白去乙酰化酶抑制剂在不同T细胞淋巴瘤系中的抗肿瘤效果

British Journal of Haematology

IF3.8

2025-10-050

PRE

A phase I study of MLN4924 and belinostat in relapsed/refractory acute myeloid leukemia or myelodysplastic syndrome

一项关于MLN4924和belinostat在复发/难治性急性髓系白血病或骨髓增生异常综合征中的I期研究

CANCER CHEMOTHERAPY AND PHARMACOLOGY

IF2.3

2025-01-173

OA

Glutaminase inhibition in combination with azacytidine in myelodysplastic syndromes: a phase 1b/2 clinical trial and correlative analyses

谷氨酰胺酶抑制联合氮杂胞苷治疗骨髓增生异常综合征: 1b/2期临床试验及相关分析

IF28.5

2024-09-190

PRE

Dinardo, Courtney D.; Verma, Divij; Baran, Natalia; Bhagat, Tushar D.; Skwarska, Anna; Lodi, Alessia; Saxena, Kapil; Cai, Tianyu; Su, Xiaoping; Guerra, Veronica A.; Poigaialwar, Gowri; Kuruvilla, Vinitha M.; Konoplev, Sergej; Gordon-Mitchell, Shanisha; Pradhan, Kith; Aluri, Srinivas; Hackman, G. Lavender; Chaudhry, Sovira; Collins, Meghan; Sweeney, Shannon R.; Busquets, Jonathan; Rathore, Atul Singh; Deng, Qing; Green, Michael R.; Grant, Steven; Demo, Susan; Choudhary, Gaurav S.; Sahu, Srabani; Agarwal, Beamon; Spodek, Mason; Thiruthuvanathan, Victor; Will, Britta; Steidl, Ulrich; Tippett, George D.; Burger, Jan; Borthakur, Gautam; Jabbour, Elias; Pemmaraju, Naveen; Kadia, Tapan; Kornblau, Steven; Daver, Naval G.; Naqvi, Kiran; Short, Nicholas J.; Garcia-Manero, Guillermo; Tiziani, Stefano; Verma, Amit; Konopleva, Marina

Azaphosphinate Dyes: A Low Molecular Weight Near-Infrared Scaffold for Development of Photoacoustic or Fluorescence Imaging Probes

氮杂膦酸酯染料: 用于开发光声或荧光成像探针的低分子量近红外支架

CHEMISTRY-A EUROPEAN JOURNAL

IF3.7

2024-02-022

OA

Coadministration of AZD 4573 and gilteritinib exhibits a potent activity in FLT3 inhibitor-sensitive and -resistant AML cells

MOLECULAR CANCER THERAPEUTICS

IF5.5

2023-12-010

PRE

Single Atom Stabilization of Phosphinate Ester-Containing Rhodamines Yields Cell Permeable Probes for Turn-On Photoacoustic Imaging

CHEMISTRY-A EUROPEAN JOURNAL

IF3.7

2023-11-103

OA

Non-canonical role for the ataxia-telangiectasia-Rad3 pathway in STAT3 activation in human multiple myeloma cells

CELLULAR ONCOLOGY

IF4.8

2023-05-015

OAAI

Bile acid regulation of C/EBPβ, CREB, and c-Jun function, via the extracellular signal-regulated kinase and c-Jun NH2-terminal kinase pathways, modulates the apoptotic response of hepatocytes

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27151

OAAI

The kinase inhibitor sorafenib induces cell death through a process involving induction of endoplasmic reticulum stress

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27245

OAAI

Blockade of histone deacetylase inhibitor-induced RelA/p65 acetylation and NF-κB activation potentiates apoptosis in leukemia cells through a process mediated by oxidative damage, XIAP downregulation, and c-jun n-terminal kinase 1 activation

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27230

OA

Bim Upregulation by Histone Deacetylase Inhibitors Mediates Interactions with the Bcl-2 Antagonist ABT-737: Evidence for Distinct Roles for Bcl-2, Bcl-xL, and Mcl-1

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-21104

OAAI

Dual mTORC1/2 Inhibition Synergistically Enhances AML Cell Death in Combination with the BCL2 Antagonist Venetoclax

CLINICAL CANCER RESEARCH

IF10.2

2023-01-187

OA

Mechanisms of myeloid leukemogenesis: Current perspectives and therapeutic objectives

IF5.7

2023-01-0117

OAAI

Disrupting autophagy in FLT3-mutant acute myeloid leukemia

IF7.9

2022-11-171

OAAI

Mechanisms underlying synergism between circularized tumor necrosis factor-related apoptosis inducing ligand and bortezomib in bortezomib-sensitive or -resistant myeloma cells

HEMATOLOGICAL ONCOLOGY

IF3.9

2022-07-142

OAAI

Chk1 Inhibition Potently Blocks STAT3 Tyrosine705 Phosphorylation, DNA-Binding Activity, and Activation of Downstream Targets in Human Multiple Myeloma Cells

MOLECULAR CANCER RESEARCH

IF4.7

2022-03-036

OA

IAP and HDAC inhibitors interact synergistically in myeloma cells through noncanonical NF-κB- and caspase-8-dependent mechanisms

IF7.1

2021-10-0112

OA