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F

Friedemann Schmidt

sanofi research and development
H指数:21
被引数:1,545

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Quantitative systems toxicology: modelling to mechanistically understand and predict drug safety

定量系统毒理学: 建模以机械地理解和预测药物安全性

Nature Reviews Drug Discovery
IF101.8
2025-10-270
PRE
Christopher E. Goldring; Giusy Russomanno; Carmen Pin; Panuwat Trairatphisan; Kylie A. Beattie; Ciarán P. Fisher; Janet Piñero; Richard J. Brennan; Diana Clausznitzer; Ian M. Copple; Theo M. de Kok; Carrie A. Duckworth; Laura I. Furlong; Barbara Füzi; Attila Gabor; Louis Gall; Jan Hengstler; Henning Hermjakob; Fiona Hunter; Danyel Jennen; Mikko Koskinen; Steven J. Kunnen; Lieve Lammens; Sebastian Lobentanzer; Marcel Mohr; Elisa Passini; D. Mark Pritchard; Rahuman S. Malik-Sheriff; Blanca Rodríguez; Eric I. Rossman; Julio Saez-Rodríguez; Friedemann Schmidt; Rowena Sison-Young; Inari Soininen; Sean Turner; Bob van de Water; Johan G. C. van Hasselt; Filippo Venezia; Jeffrey A. Willy; Derek J. Leishman; James L. Stevens; Loic Laplanche
Quantitative assessment of the usability of electromechanical human-based modelling and simulation to replace Langendorff isolated rabbit heart experiments in the preclinical setting

量化评估机电人源建模与仿真在预临床环境中替代Langendorff离体兔心实验的可用性

Frontiers in Pharmacology
IF4.8
2025-10-240
OAAI
Maxx Holmes†; Hector Martinez-Navarro†; Marcel Mohr; Jean-Marie Chambard; Veronique Ballet; Eva Vermersch; Ambroise Garry; Friedemann Schmidt; Blanca Rodriguez
The state of the art in secondary pharmacology and its impact on the safety of new medicines (May, 10.1038/s41573-024-00942-3, 2024)

次要药理学的最新技术及其对新药安全性的影响 (10.1038/s41573-024-00942-3，2024 5月)

NATURE REVIEWS DRUG DISCOVERY
IF101.8
2024-06-170
OA
Brennan, Richard J.; Jenkinson, Stephen; Brown, Andrew; Delaunois, Annie; Dumotier, Berengere; Pannirselvam, Malar; Rao, Mohan; Ribeiro, Lyn Rosenbrier; Schmidt, Friedemann; Sibony, Alicia; Timsit, Yoav; Sales, Vicencia Toledo; Armstrong, Duncan; Lagrutta, Armando; Mittlestadt, Scott W.; Naven, Russell; Peri, Ravikumar; Roberts, Sonia; Vergis, James M.; Valentin, Jean-Pierre
The state of the art in secondary pharmacology and its impact on the safety of new medicines

二级药理学的最新技术及其对新药安全性的影响

NATURE REVIEWS DRUG DISCOVERY
IF101.8
2024-05-216
PRE
Brennan, Richard J.; Jenkinson, Stephen; Brown, Andrew; Delaunois, Annie; Dumotier, Berengere; Pannirselvam, Malar; Rao, Mohan; Ribeiro, Lyn Rosenbrier; Schmidt, Friedemann; Sibony, Alicia; Timsit, Yoav; Sales, Vicencia Toledo; Armstrong, Duncan; Lagrutta, Armando; Mittlestadt, Scott W.; Naven, Russell; Peri, Ravikumar; Roberts, Sonia; Vergis, James M.; Valentin, Jean-Pierre
Developing a pragmatic consensus procedure supporting the ICH S1B(R1) weight of evidence carcinogenicity assessment
FRONTIERS IN TOXICOLOGY
IF4.6
2024-04-053
OAAI
Bassan, Arianna; Steigerwalt, Ronald; Keller, Douglas; Beilke, Lisa; Bradley, Paul M.; Bringezu, Frank; Brock, William J.; Burns-Naas, Leigh Ann; Chambers, Jon; Cross, Kevin; Dorato, Michael; Elespuru, Rosalie; Fuhrer, Douglas; Hall, Frances; Hartke, Jim; Jahnke, Gloria D.; Kluxen, Felix M.; Mcduffie, Eric; Schmidt, Friedemann; Valentin, Jean-Pierre; Woolley, David; Zane, Doris; Myatt, Glenn J.
Mechanistic investigations of the liver toxicity of the free fatty acid receptor 1 agonist fasiglifam (TAK875) and its primary metabolites
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
IF2.8
2019-05-0822
PREAI
Ackerson, Timothy; Amberg, Alexander; Atzrodt, Jens; Arabeyre, Catherine; Defossa, Elisabeth; Dorau, Martina; Dudda, Angela; Dwyer, Jacquelyn; Holla, Wolfgang; Kissner, Thomas; Kohlmann, Markus; Kuerzel, Ulrich; Panczel, Jozsef; Rajanna, Shibani; Riedel, Jens; Schmidt, Friedemann; Waese, Kerstin; Weitz, Dietmar; Derdau, Volker

研究方向

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A
Andreas Czich
H 指数:21论文数:49被引数:1,367
J
Jan Wenzel
H 指数:15论文数:31被引数:5,615
G
Gerhard Heßler
H 指数:27论文数:103被引数:2,963
R
Richard Brennan
H 指数:33论文数:126被引数:4,800
J
Jean‐Pierre Valentin
H 指数:45论文数:364被引数:6,227
B
Blanca Rodríguez
H 指数:73论文数:775被引数:2.3万
N
Nis Halland
H 指数:25论文数:64被引数:3,143
M
Marcel Mohr
H 指数:5论文数:21被引数:88
S
Stefan M. Kast
H 指数:29论文数:135被引数:2,728
A
Alexander Amberg
H 指数:32论文数:73被引数:7,720