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K

Kathryn A. Whitehead

carnegie mellon university

40H指数
112论文数
1.3W被引数
收录论文 68
发表时间
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PEG-associated efficacy loss in lipid nanoparticles persists across formulation modifications for mRNA deliveryPEG相关脂质纳米颗粒在mRNA递送中的效损失在配方改良中持续存在
errDrug Delivery and Translational Research
IF5.5
err2026-10-12
err0
errOAAI
errMariah L. Arral; Namit Chaudhary; Katherine C. Fein; Alexandra N. Newby; Saigopalakrishna S. Yerneni; Jilian R. Melamed; Samuel T. LoPresti; Daria M. Strelkova Petersen; Kathryn A. Whitehead
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err收藏
Author Correction: Influence of protein aggregates, extracellular vesicles, and lipoprotein fusion on ionizable lipid nanoparticles protein corona analysis作者更正：蛋白质聚集物、外泌体和脂蛋白融合对可电离脂质纳米颗粒蛋白冠分析的影响
errNature Communications
IF15.7
err2026-09-10
err0
errOAAI
errBabak Borhan; Amanda M. Murray; Amir Ata Saei; Bahareh Ghaffari; James E. Jackson; Naseeha Mohammed; Michael J. Mitchell; Hojatollah Vali; Kathryn A. Whitehead; Morteza Mahmoudi
err分享
err收藏
Influence of protein aggregates, extracellular vesicles, and lipoprotein fusion on ionizable lipid nanoparticles protein corona analysis蛋白质聚集物、外泌体及脂蛋白融合对可电离脂质纳米颗粒蛋白冠分析的影响
errNature Communications
IF15.7
err2026-06-12
err0
errOAAI
errBabak Borhan; Amanda M. Murray; Amir Ata Saei; Bahareh Ghaffari; James E. Jackson; Naseeha Mohammed; Michael J. Mitchell; Hojatollah Vali; Kathryn A. Whitehead; Morteza Mahmoudi
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err收藏
Enhanced Epigenetic Modulation via mRNA-Encapsulated Lipid Nanoparticles Enables Targeted Anti-inflammatory Control通过封装mRNA的脂质纳米颗粒增强表观遗传调控，实现靶向抗炎控制
errACS Synthetic Biology
IF3.9
err2026-01-01
err0
errOAAI
errMokhtari, Tahere; Taheri, Mohammad N.; Akhlaghi, Sarah; Aryannejad, Armin; Xiang, Yuda; Mahajan, Vineet; Keshavarz, Kamyar; Kiani, Amirreza; Yang, Samantha; Lopresti, Samuel; Legraw, Ryan; Whitehead, Kathryn A.; Kiani, Samira
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The great lipid hunt伟大的脂质搜寻
errNature Chemical Engineering
IF0
err2025-12-01
err0
PREAI
errWhitehead, Kathryn A.
err分享
err收藏
Designing around immune memory to counter PEG immunogenicity围绕免疫记忆设计以对抗PEG免疫原性
errNature Materials
IF38.5
err2025-10-15
err0
PREAI
errNamit Chaudhary; Kathryn A. Whitehead
err分享
err收藏
Limiting endosomal damage sensing reduces inflammation triggered by lipid nanoparticle endosomal escape限制内体损伤传感可减少由脂质纳米颗粒内体逃逸引发的炎症
errNature Nanotechnology
IF34.9
err2025-08-11
err0
PREAI
errSerena Omo-Lamai; Yufei Wang; Manthan N. Patel; Aleksa Milosavljevic; Daniel Zuschlag; Subhajit Poddar; Jichuan Wu; Liuqian Wang; Fengyi Dong; Carolann Espy; Aparajeeta Majumder; Eno-Obong Essien; Mengwen Shen; Breana Channer; Tyler E. Papp; Michael Tobin; Rhea Maheshwari; Sumin Jeong; Sofia Patel; Anit Shah; Shruthi Murali; Liam S. Chase; Marco E. Zamora; Mariah L. Arral; Oscar A. Marcos-Contreras; Jacob W. Myerson; Christopher A. Hunter; Dennis Discher; Peter J. Gaskill; Andrew Tsourkas; Vladimir R. Muzykantov; Igor Brodsky; Sunny Shin; Kathryn A. Whitehead; Hamideh Parhiz; Jeremy Katzen; Jonathan J. Miner; Dirk Trauner; Jacob S. Brenner
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Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal-Organic Frameworks纳米金属有机框架用于mRNA封装和基因传递的合成策略
errADVANCED FUNCTIONAL MATERIALS
IF19
err2025-05-19
err0
errOAAI
errLawson, HD; Nguyen, HH; Lee, KJ; Wongsuwan, N; Tupe, A; Lu, MR; Arral, ML; Behre, A; Ling, ZH; Whitehead, KA; Feinberg, AW; Ren, X; Zheng, SY
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Maternal milk cell components are uptaken by infant liver macrophages via extracellular vesicle mediated transport婴儿肝脏巨噬细胞通过细胞外囊泡介导的运输吸收母体乳汁细胞成分
errFASEB JOURNAL
IF4.2
err2025-01-21
err0
errOAAI
errDoerfler, Rose; Yerneni, Saigopalakrishna; Lopresti, Samuel; Chaudhary, Namit; Newby, Alexandra; Melamed, Jilian R.; Malaney, Angela; Whitehead, Kathryn A.
err分享
err收藏
ENGINEERING MRNA THERAPIES FOR BRAIN TUMORS
errNEURO-ONCOLOGY
IF13.4
err2024-11-11
err0
PREAI
errYerneni, Saigopalakrishna; Azambuja, Juliana Hofstatter; Strelkova-Petersen, Daria; Gallagher, Brendan; Kim, Julie Shin; Chaudhary, Namit; Zhao, Yongxin; Lucas, Peter; McAllister-Lucas, Linda; Pardi, Norbert; Weissman, Drew; Whitehead, Kathryn
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Amine headgroups in ionizable lipids drive immune responses to lipid nanoparticles by binding to the receptors TLR4 and CD1d可电离脂质中的胺头基通过与受体TLR4和CD1d结合来驱动对脂质纳米颗粒的免疫反应
errNATURE BIOMEDICAL ENGINEERING
IF26.6
err2024-10-03
err3
PREAI
errChaudhary, Namit; Kasiewicz, Lisa N.; Newby, Alexandra N.; Arral, Mariah L.; Yerneni, Saigopalakrishna S.; Melamed, Jilian R.; Lopresti, Samuel T.; Fein, Katherine C.; Petersen, Daria M. Strelkova; Kumar, Sushant; Purwar, Rahul; Whitehead, Kathryn A.
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A translational framework to DELIVER nanomedicines to the clinic将纳米药物提供给临床的翻译框架
errNATURE NANOTECHNOLOGY
IF34.9
err2024-09-06
err4
PREAI
errJoyce, Paul; Allen, Christine J.; Alonso, Maria Jose; Ashford, Marianne; Bradbury, Michelle S.; Germain, Matthieu; Kavallaris, Maria; Langer, Robert; Lammers, Twan; Peracchia, Maria Teresa; Popat, Amirali; Prestidge, Clive A.; Rijcken, Cristianne J. F.; Sarmento, Bruno; Schmid, Ruth B.; Schroeder, Avi; Subramaniam, Santhni; Thorn, Chelsea R.; Whitehead, Kathryn A.; Zhao, Chun-Xia; Santos, Helder A.
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Branched-Tail Lipid Nanoparticles for Intravenous mRNA Delivery to Lung Immune, Endothelial, and Alveolar Cells in Mice分支尾脂质纳米颗粒用于小鼠肺免疫，内皮和肺泡细胞的静脉内mRNA递送
errADVANCED HEALTHCARE MATERIALS
IF9.6
err2024-07-02
err1
PREAI
errPetersen, Daria M. Strelkova; Weiss, Ryan M.; Hajj, Khalid A.; Yerneni, Saigopalakrishna S.; Chaudhary, Namit; Newby, Alexandra N.; Arral, Mariah L.; Whitehead, Kathryn A.
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Lipid nanoparticle structure and delivery route during pregnancy dictate mRNA potency, immunogenicity, and maternal and fetal outcomes
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2024-03-04
err7
errOAAI
errChaudhary, Namit; Newby, Alexandra N.; Arral, Mariah L.; Yerneni, Saigopalakrishna S.; Lopresti, Samuel T.; Doerfler, Rose; Petersen, Daria M. Strelkova; Montoya, Catalina; Kim, Julie S.; Fox, Bethany; Coon, Tiffany; Malaney, Angela; Sadovsky, Yoel; Whitehead, Kathryn A.
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Non-Viral RNA Delivery During Pregnancy: Opportunities and Challenges
errSMALL
IF12.1
err2023-12-25
err2
errOAAI
errChaudhary, Namit; Newby, Alexandra N.; Whitehead, Kathryn A.
err分享
err收藏
Spray dried lipid nanoparticle formulations enable intratracheal delivery of mRNA喷雾干燥的脂质纳米颗粒制剂能够实现mRNA的气管内递送
errJOURNAL OF CONTROLLED RELEASE
IF11.5
err2023-11-01
err15
PREAI
errFriis, Kristina Pagh; Gracin, Sandra; Oag, Steven; Leijon, Alexandra; Sand, Elin; Lindberg, Botilda; Lazaro-Ibanez, Elisa; Lindqvist, Johnny; Whitehead, Kathryn A.; Bak, Annette
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Placental drug transport and fetal exposure during pregnancy is determined by drug molecular size, chemistry, and conformation
errJOURNAL OF CONTROLLED RELEASE
IF11.5
err2023-09-01
err4
errOAAI
errFein, Katherine C.; Arral, Mariah L.; Kim, Julie S.; Newby, Alexandra N.; Whitehead, Kathryn A.
err分享
err收藏
Enabling mRNA medicine for brain tumors
errCANCER RESEARCH
IF16.6
err2023-04-04
err1
PREAI
errYerneni, Saigopalakrishna S.; Azambuja, Juliana H.; Lucas, Peter C.; McAllister-Lucas, Linda; Whitehead, Kathryn A.
err分享
err收藏
Ionizable lipid nanoparticles deliver mRNA to pancreatic ? cells via macrophage-mediated gene transfer可电离脂质纳米粒将mRNA递送至胰腺？细胞通过巨噬细胞介导的基因转移
errSCIENCE ADVANCES
IF12.5
err2023-01-27
err61
errOAAI
errMelamed, Jilian R.; Yerneni, Saigopalakrishna S.; Arral, Mariah L.; LoPresti, Samuel T.; Chaudhary, Namit; Sehrawat, Anuradha; Muramatsu, Hiromi; Alameh, Mohamad-Gabriel; Pardi, Norbert; Weissman, Drew; Gittes, George K.; Whitehead, Kathryn A.
err分享
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Factor XII Silencing Using siRNA Prevents Thrombus Formation in a Rat Model of Extracorporeal Life Support
errASAIO JOURNAL
IF2.3
err2022-12-27
err3
errOAAI
errUmei, Nao; Shin, Suji; Lai, Angela; Miller, Jennifer; Roberts, Kalliope; Strelkova, Daria; Chaudhary, Namit; Ichiba, Shingo; Sakamoto, Atsuhiro; Whitehead, Kathryn; Cook, Keith
err分享
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研究方向

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