未登录 Safety and Immunogenicity of a Severe Acute Respiratory Syndrome Coronavirus 2 Spike Subunit Vaccine Stabilized in the Prefusion Conformation by a Second-Generation Molecular Clamp and Evaluated in Adults Aged 18-55 Years: A Randomized, Double-Blind, Active Comparator, Phase I Trial 一项利用第二代分子夹稳定前融合构象的严重急性呼吸综合征冠状病毒2刺突亚单位疫苗的安全性与免疫原性研究：一项在18-55岁成人中进行的随机、双盲、活性对照、I期临床试验 Chappell, Keith J.; Mordant, Francesca L.; Amarilla, Alberto A.; Modhiran, Naphak; Liang, Benjamin; Li, Zheyi; Lackenby, Julia A.; Jaberolansar, Noushin; O'Donnell, Jake; Kienzle, Vivian; Kommajosyula, Varsha; Tardiota, Nicolas; Bennet, Jillian K.; Henderson, Christina L.; Dalrymple, Rhiannon L.; Goh, Justin; Hoger, Kym; Gillard, Marianne; Jones, Martina L.; Hughes, Karen; Hughes, Ben; Barnes, James; Reading, Patrick C.; Ranasinghe, Charani; Subbarao, Kanta; Munro, Trent P.; Young, Paul R.; Watterson, Daniel 分享 收藏
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Harnessing metabolic plasticity in CHO cells for enhanced perfusion cultivation 利用CHO细胞的代谢可塑性来增强灌注培养 Noebel, Matthias; Barry, Craig; Macdonald, Michael A.; Baker, Kym; Shave, Evan; Mahler, Stephen; Munro, Trent; Martinez, Veronica S.; Nielsen, Lars K.; Marcellin, Esteban 分享 收藏
Long-term safety and immunogenicity of an MF59- adjuvanted spike glycoprotein-clamp vaccine for SARS-CoV-2 in adults aged 18-55 years or >56 years: 12-month results from a randomised, double-blind, placebo-controlled, phase 1 trial Chappell, Keith J.; Mordant, Francesca L.; Amarilla, Alberto A.; Modhiran, Naphak; Liang, Benjamin; Li, Zheyi; Wijesundara, Danushka K.; Lackenby, Julia A.; Grif, Paul; Bennet, Jillian K.; Hensen, Luca; Zhang, Wuji; Nguyen, Thi H. O.; Tran, Mai H.; Tapley, Peter; Barnes, James; Reading, Patrick C.; Kedzierska, Katherine; Ranasinghe, Charani; Subbarao, Kanta; Watterson, Daniel; Young, Paul R.; Munro, Trent P. 分享 收藏
mRNA vaccine quality analysis using RNA sequencing Gunter, Helen M.; Idrisoglu, Senel; Singh, Swati; Han, Dae Jong; Ariens, Emily; Peters, Jonathan R.; Wong, Ted; Cheetham, Seth W.; Xu, Jun; Rai, Subash Kumar; Feldman, Robert; Herbert, Andy; Marcellin, Esteban; Tropee, Romain; Munro, Trent; Mercer, Tim R. 分享 收藏
Broad immunity to SARS-CoV-2 variants of concern mediated by a SARS-CoV-2 receptor-binding domain protein vaccine SARS-CoV-2受体结合域蛋白疫苗介导的对SARS-CoV-2相关变异的广泛免疫 Deliyannis, Georgia; Gherardin, Nicholas A.; Wong, Chinn Yi; Grimley, Samantha L.; Cooney, James P.; Redmond, Samuel J.; Ellenberg, Paula; Davidson, Kathryn C.; Mordant, Francesca L.; Smith, Tim; Gillard, Marianne; Lopez, Ester; McAuley, Julie; Tan, Chee Wah; Wang, Jing J.; Zeng, Weiguang; Littlejohn, Mason; Zhou, Runhong; Chan, Jasper Fuk-Woo; Chen, Zhi-wei; Hartwig, Airn E.; Bowen, Richard; Mackenzie, Jason M.; Vincan, Elizabeth; Torresi, Joseph; Kedzierska, Katherine; Pouton, Colin W.; Gordon, Tom P.; Wang, Lin-fa; Kent, Stephen J.; Wheatley, Adam K.; Lewin, Sharon R.; Subbarao, Kanta; Chung, Amy W.; Pellegrini, Marc; Munro, Trent; Nolan, Terry; Rockman, Steven; Jackson, David C.; Purcell, Damian F. J.; Godfrey, Dale I. 分享 收藏
RNA trafficking signals in human immunodeficiency virus type 1 Mouland, AJ; Xu, HB; Cui, HY; Krueger, W; Munro, TP; Prasol, M; Mercier, J; Rekosh, D; Smith, R; Barbarese, E; Cohen, EA; Carson, JH 分享 收藏
SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike protein Albornoz, Eduardo A.; Amarilla, Alberto A.; Modhiran, Naphak; Parker, Sandra; Li, Xaria X.; Wijesundara, Danushka K.; Aguado, Julio; Zamora, Adriana Pliego; McMillan, Christopher L. D.; Liang, Benjamin; Peng, Nias Y. G.; Sng, Julian D. J.; Saima, Fatema Tuj; Fung, Jenny N.; Lee, John D.; Paramitha, Devina; Parry, Rhys; Avumegah, Michael S.; Isaacs, Ariel; Lo, Martin W.; Miranda-Chacon, Zaray; Bradshaw, Daniella; Salinas-Rebolledo, Constanza; Rajapakse, Niwanthi W.; Wolvetang, Ernst J.; Munro, Trent P.; Rojas-Fernandez, Alejandro; Young, Paul R.; Stacey, Katryn J.; Khromykh, Alexander A.; Chappell, Keith J.; Watterson, Daniel; Woodruff, Trent M. 分享 收藏
Engineering death resistance in CHO cells for improved perfusion culture CHO细胞的工程抗死亡能力，以改善灌注培养 MacDonald, Michael A.; Nobel, Matthias; Martinez, Veronica S.; Baker, Kym; Shave, Evan; Gray, Peter P.; Mahler, Stephen; Munro, Trent; Nielsen, Lars K.; Marcellin, Esteban 分享 收藏
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Modeling apoptosis resistance in CHO cells with CRISPR-mediated knockouts of Bak1, Bax, and Bok 通过CRISPR介导的Bak1，Bax和Bok敲除模拟CHO细胞的凋亡抗性 MacDonald, Michael A.; Barry, Craig; Groves, Teddy; Martinez, Veronica S.; Gray, Peter P.; Baker, Kym; Shave, Evan; Mahler, Stephen; Munro, Trent; Marcellin, Esteban; Nielsen, Lars K. 分享 收藏
A call to action for translational sciences in COVID-19 and future pandemics 在COVID-19和未来的流行病中呼吁转化科学的行动 Wan, Kanny K.; Davis, Danielle; Lee, Taylor N.; Ford-Scheimer, Stephanie L.; Andreu, Antonio L.; Bietrix, Florence; Bryans, Justin; Castro, Marco T.; Chiba, Nobuyoshi; Faupel-Badger, Jessica M.; Haynes, Brittany; Hirasawa, Ryutaro; Morel, Carlos M.; Souza, Thiago Moreno L.; Morrow, David; Munro, Trent; Newman, Stuart; Ussi, Anton E.; Zorzal, Poliana B.; Hall, Matthew D.; Lo, Donald C.; Cutillo, Christine M. 分享 收藏
Perfusion culture of Chinese Hamster Ovary cells for bioprocessing applications 用于生物加工应用的中国仓鼠卵巢细胞的灌注培养 MacDonald, Michael A.; Nobel, Matthias; Recinos, Dinora Roche; Martinez, Veronica S.; Schulz, Benjamin L.; Howard, Christopher B.; Baker, Kym; Shave, Evan; Lee, Yih Yean; Marcellin, Esteban; Mahler, Stephen; Nielsen, Lars Keld; Munro, Trent 分享 收藏
Safety and immunogenicity of an MF59-adjuvanted spike glycoprotein-clamp vaccine for SARS-CoV-2: a randomised, double-blind, placebo-controlled, phase 1 trial Chappell, Keith J.; Mordant, Francesca L.; Li, Zheyi; Wijesundara, Danushka K.; Ellenberg, Paula; Lackenby, Julia A.; Cheung, Stacey T. M.; Modhiran, Naphak; Avumegah, Michael S.; Henderson, Christina L.; Hoger, Kym; Griffin, Paul; Bennet, Jillian; Hensen, Luca; Zhang, Wuji; Nguyen, Thi H. O.; Marrero-Hernandez, Sara; Selva, Kevin J.; Chung, Amy W.; Tran, Mai H.; Tapley, Peter; Barnes, James; Reading, Patrick C.; Nicholson, Suellen; Corby, Stavroula; Holgate, Thomas; Wines, Bruce D.; Hogarth, P. Mark; Kedzierska, Katherine; Purcell, Damian F. J.; Ranasinghe, Charani; Subbarao, Kanta; Watterson, Daniel; Young, Paul R.; Munro, Trent P. 分享 收藏
Mutational and biophysical robustness in a prestabilized monobody Chandler, Peter G.; Tan, Li Lynn; Porebski, Benjamin T.; Green, James S.; Riley, Blake T.; Broendum, Sebastian S.; Hoke, David E.; Falconer, Robert J.; Munro, Trent P.; Buckle, Malcolm; Jackson, Colin J.; Buckle, Ashley M. 分享 收藏
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