Alphonsus H. C. Ng - Publications, H-index & Citations

Alphonsus H. C. Ng

Institute for Systems Biology

28H指数

60论文数

4.5K被引数

收录论文 30

发表时间

Sequential transcriptional waves and NF-κB-driven chromatin remodeling direct drug-induced dedifferentiation in cancer 顺序转录波和nf-κb驱动的染色质重塑直接药物诱导的癌症去分化

Nature Communications

IF15.7

2026-04-15

OAAI

Yapeng Su; Chunmei Liu; Xiang Lu; Hui-Yu Chuang; Guideng Li; Shiqun Shao; Yan Kong; Jihoon W. Lee; Rachel H. Ng; Stephanie Wong; Lidia Robert; Charles Warden; Victoria Liu; Jie Chen; Zhuo Wang; Guangrong Qin; Yin Tang; Hanjun Cheng; Alphonsus H. C. Ng; Daniel Chen; Songming Peng; Min Xue; Dazy Johnson; Yu Xu; Jinhui Wang; Xiwei Wu; Ilya Shmulevich; Qihui Shi; Raphael Levine; Antoni Ribas; David Baltimore; Jun Guo; James R. Heath; Wei Wei

Organ-specific immunity: A tissue analysis framework for investigating local immune responses to SARS-CoV-2

CELL REPORTS

IF6.9

2023-10-01

OAAI

Ng, Alphonsus H. C.; Hu, Huiqian; Wang, Kai; Scherler, Kelsey; Warren, Sarah E.; Zollinger, Daniel R.; McKay-Fleisch, Jill; Sorg, Kristina; Beechem, Joseph M.; Ragaglia, Emily; Lacy, J. Matthew; Smith, Kelly D.; Marshall, Desiree A.; Bundesmann, Michael M.; de Castilla, Diego Lopez; Corwin, David; Yarid, Nicole; Knudsen, Beatrice S.; Lu, Yue; Goldman, Jason D.; Heath, James R.

Large libraries of single-chain trimer peptide-MHCs enable antigen-specific CD8+T cell discovery and analysis

COMMUNICATIONS BIOLOGY

IF5.1

2023-05-16

OAAI

Chour, William; Choi, Jongchan; Xie, Jingyi; Chaffee, Mary E. E.; Schmitt, Thomas M. M.; Finton, Kathryn; DeLucia, Diana C. C.; Xu, Alexander M. M.; Su, Yapeng; Chen, Daniel G. G.; Zhang, Rongyu; Yuan, Dan; Hong, Sunga; Ng, Alphonsus H. C.; Butler, Jonah Z. Z.; Edmark, Rick A. A.; Jones, Lesley C. C.; Murray, Kim M. K. M.; Peng, Songming; Li, Guideng; Strong, Roland K. K.; Lee, John K. K.; Goldman, Jason D. D.; Greenberg, Philip D. D.; Heath, James R. R.

Monitoring of neoantigens and adoptively transferred personalized neoTCR T cell populations in the tumor and PBMCs of patients with solid tumors

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Foy, Susan; Wang, Cliff; Yuen, Benjamin; Said, Sara; Quach, Boi; Hoover, Jonathan; Nayak, Saparya; Hunter, Theresa; Pan, Zheng; Smith, Chad; Borrman, Tyler; Stawiski, Eric; Ng, Alphonsus H. C.; Lu, Yue; Heath, James; Mandl, Stefanie

A PHASE I STUDY OF PERSONALIZED ADOPTIVE TCR T CELL THERAPY IN PATIENTS WITH SOLID TUMORS: SAFETY, EFFICACY, AND T CELL TRAFFICKING TO TUMORS OF NON-VIRALLY GENE EDITED T CELLS

JOURNAL FOR IMMUNOTHERAPY OF CANCER

IF10.6

2022-12-08

OAAI

Foy, Susan; Jacoby, Kyle; Bota, Daniela; Hunter, Theresa; Schoenfeld, Adam; Pan, Zheng; Stawiski, Eric; Ma, Yan; Lu, William; Peng, Songming; Wang, Clifford; Yuen, Benjamin; Dalmas, Olivier; Heeringa, Katharine; Sennino, Barbara; Conroy, Andy; Bethune, Michael; Mende, Ines; White, William; Kukreja, Monica; Gunturu, Swetha; Humphrey, Emily; Hussaini, Adeel; An, Duo; Quach, Boi; Ng, Alphonsus; Lu, Yue; Smith, Chad; Campbell, Katie; Anaya, Daniel; Skrdlant, Lindsey; Huang, Eva; Mendoza, Ventura; Mathur, Jyoti; Dengler, Luke; Purandare, Bhamini; Moot, Robert; Yi, Michael; Funke, Roel; Sibley, Alison; Stallings-Schmitt, Todd; Oh, David; Chmielowski, Bartosz; Abedi, Mehrdad; Yuan, Yuan; Sosman, Jeff; Lee, Sylvia; Williams, Claire; Kim, Sean; Keefe, Matthwe; Leon, Michael; Kim, Youngmi; Reeves, Jason; Goldman, Wes; Baltimore, David; Heath, James; Franzusoff, Alex; Ribas, Antoni; Rao, Arati; Mandl, Stefanie

Non-viral precision T cell receptor replacement for personalized cell therapy 用于个性化细胞治疗的非病毒精确T细胞受体替代

NATURE REVIEWS DRUG DISCOVERY

IF101.8

2022-11-10

130

OAAI

Foy, Susan P. P.; Jacoby, Kyle; Bota, Daniela A. A.; Hunter, Theresa; Pan, Zheng; Stawiski, Eric; Ma, Yan; Lu, William; Peng, Songming; Wang, Clifford L. L.; Yuen, Benjamin; Dalmas, Olivier; Heeringa, Katharine; Sennino, Barbara; Conroy, Andy; Bethune, Michael T. T.; Mende, Ines; White, William; Kukreja, Monica; Gunturu, Swetha; Humphrey, Emily; Hussaini, Adeel; An, Duo; Litterman, Adam J. J.; Quach, Boi Bryant; Ng, Alphonsus H. C.; Lu, Yue; Smith, Chad; Campbell, Katie M. M.; Anaya, Daniel; Skrdlant, Lindsey; Huang, Eva Yi-Hsuan; Mendoza, Ventura; Mathur, Jyoti; Dengler, Luke; Purandare, Bhamini; Moot, Robert; Yi, Michael C. C.; Funke, Roel; Sibley, Alison; Stallings-Schmitt, Todd; Oh, David Y. Y.; Chmielowski, Bartosz; Abedi, Mehrdad; Yuan, Yuan; Sosman, Jeffrey A. A.; Lee, Sylvia M. M.; Schoenfeld, Adam J. J.; Baltimore, David; Heath, James R. R.; Franzusoff, Alex; Ribas, Antoni; Rao, Arati V. V.; Mandl, Stefanie J. J.

Resolution of tissue signatures of therapy response in patients with recurrent GBM treated with neoadjuvant anti-PD1

NATURE COMMUNICATIONS

IF15.7

2021-06-29

OAAI

Lu, Yue; Ng, Alphonsus H. C.; Chow, Frances E.; Everson, Richard G.; Helmink, Beth A.; Tetzlaff, Michael T.; Thakur, Rohit; Wargo, Jennifer A.; Cloughesy, Timothy F.; Prins, Robert M.; Heath, James R.

Raman-guided subcellular pharmaco-metabolomics for metastatic melanoma cells

NATURE COMMUNICATIONS

IF15.7

2020-09-24

114

OAAI

Du, Jiajun; Su, Yapeng; Qian, Chenxi; Yuan, Dan; Miao, Kun; Lee, Dongkwan; Ng, Alphonsus H. C.; Wijker, Reto S.; Ribas, Antoni; Levine, Raphael D.; Heath, James R.; Wei, Lu

Strategies to improve the sensitivity and ranking ability of neoantigen prediction methods: Report on the results of the Tumor nEoantigen SeLection Alliance (TESLA)

CANCER RESEARCH

IF16.6

2020-08-15

PREAI

Wells, Daniel K.; Dang, Kristen; Hubbard-Lucey, Vanessa M.; Sheehan, Kathleen C.; Lamb, Andrew; Ward, Jeffrey P.; Sidney, John; Blazquez, Ana B.; Rech, Andrew J.; Zaretsky, Jesse; Anduix, Begonya Comin; Ng, Alphonsus H.; Chour, William; Yu, Thomas, V; Rizvi, Hira; Chen, Jia; Manning, Patrice; Merghoub, Taha; Guinney, Justin; Kolom, Adam; Selinsky, Cheryl; Ribas, Antoni; Hellmannn, Matthew D.; Schumacher, Ton N.; Hacohen, Nir; Kvistborg, Pia; Sette, Alessandro; Heath, James R.; Bhardwaj, Nina; Ramsdell, Fred; Schreiber, Robert D.; Defranoux, Nadine A.

4D electron microscopy of T cell activation T细胞活化的4D电子显微镜

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2019-10-14

OAAI

Lu, Yue; Yoo, Byung-Kuk; Ng, Alphonsus H. C.; Kim, Jungwoo; Yeom, Sinchul; Tang, Jau; Lin, Milo M.; Zewail, Ahmed H.; Heath, James R.

Sensitive Detection and Analysis of Neoantigen-Specific T Cell Populations from Tumors and Blood

CELL REPORTS

IF6.9

2019-09-01

OAAI

Peng, Songming; Zaretsky, Jesse M.; Ng, Alphonsus H. C.; Chour, William; Bethune, Michael T.; Choi, Jongchan; Hsu, Alice; Holman, Elizabeth; Ding, Xiaozhe; Guo, Katherine; Kim, Jungwoo; Xu, Alexander M.; Heath, John E.; Noh, Won Jun; Zhou, Jing; Su, Yapeng; Lu, Yue; McLaughlin, Jami; Cheng, Donghui; Witte, Owen N.; Baltimore, David; Ribas, Antoni; Heath, James R.

MATE-Seq: microfluidic antigen-TCR engagement sequencing

LAB ON A CHIP

IF5.4

2019-01-01

OAAI

Ng, Alphonsus H. C.; Peng, Songming; Xu, Alexander M.; Noh, Won Jun; Guo, Katherine; Bethune, Michael T.; Chour, William; Choi, Jongchan; Yang, Sung; Baltimore, David; Heath, James R.

A digital microfluidic system for serological immunoassays in remote settings

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2018-04-25

134

PREAI

Ng, Alphonsus H. C.; Fobel, Ryan; Fobel, Christian; Lamanna, Julian; Rackus, Darius G.; Summers, Aimee; Dixon, Christopher; Dryden, Michael D. M.; Lam, Charis; Ho, Man; Mufti, Nooman S.; Lee, Victor; Asri, Mohd Afiq Mohd; Sykes, Edward A.; Chamberlain, M. Dean; Joseph, Rachael; Ope, Maurice; Scobie, Heather M.; Knipes, Alaine; Rota, Paul A.; Marano, Nina; Chege, Paul M.; Njuguna, Mary; Nzunza, Rosemary; Kisangau, Ngina; Kiogora, John; Karuingi, Michael; Burton, John Wagacha; Borus, Peter; Lam, Eugene; Wheeler, Aaron R.

Towards a personalized approach to aromatase inhibitor therapy: a digital microfluidic platform for rapid analysis of estradiol in core-needle-biopsies

LAB ON A CHIP

IF5.4

2017-01-01

PREAI

Abdulwahab, Sara; Ng, Alphonsus H. C.; Chamberlain, M. Dean; Ahmado, Hend; Behan, Lucy-Ann; Gomaa, Hala; Casper, Robert F.; Wheeler, Aaron R.

Electrochemiluminescence on digital microfluidics for microRNA analysis

BIOSENSORS & BIOELECTRONICS

IF10.5

2016-03-01

PREAI

Shamsi, Mohtashim H.; Choi, Kihwan; Ng, Alphonsus H. C.; Chamberlain, M. Dean; Wheeler, Aaron R.