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收藏分享 收藏 分享 收藏 分享 收藏 分享 收藏 Recurrent CACNA1HE282K is a gain-of-function mutation associated with primary hyperaldosteronism复发性CACNA1HE282K是与原发性醛固酮增多症相关的功能获得性突变
Li, Ruyi; Jiang, Yiran; Chen, Qiujing; Zhao, Yaxue; Lu, Kechen; Nie, Aifang; Zhang, Cui; Su, Tingwei; Jiang, Lei; Zhou, Weiwei; Zhong, Xu; Wu, Luming; Han, Rulai; Ye, Lei; Wang, Weiqing 分享 收藏 分享 收藏 分享 收藏 Integrating Single-Cell Transcriptome-Wide Mendelian Randomization and Differentially Expressed Gene Analyses to Prioritize Dynamic Immune-Related Drug Targets for Cancers整合单细胞转录组范围的孟德尔随机化和差异表达基因分析，以优先考虑癌症的动态免疫相关药物靶标Zheng, Jie; Yang, Qian; Liu, Haoyu; Zhao, Huiling; Wang, Shuangyuan; Liu, Yi; Wu, Xueyan; Ding, Yilan; Ying, Hui; Ye, Youqiu; Huang, Xi; Ye, Lei; Zheng, Ruizhi; Lin, Hong; Li, Mian; Wang, Tiange; Zhao, Zhiyun; Xu, Min; Duan, Yi; Guo, Hao; Yuan, Zhongshang; Haycock, Philip; Davey Smith, George; Martin, Richard M.; Ning, Guang; Hu, Fang; Wang, Weiqing; Gaunt, Tom R.; Lu, Jieli; Bi, Yufang 分享 收藏 分享 收藏 Sleep Phenotypes, Genetic Susceptibility, and Risk of Obesity in Patients With Type 2 Diabetes: A National Prospective Cohort Study睡眠表型、遗传易感性与2型糖尿病患者肥胖风险：一项国家前瞻性队列研究Xi, Lei; Li, Li; Fu, Songbo; Dai, Yuancheng; Shi, Juan; Yu, Yanmei; Peng, Ying; Qiu, Hongmei; Kuang, Jinsong; Lu, Hongyun; Shao, Huige; Yuan, Chunlei; Wang, Xiaohu; Zhang, Ping; Li, Sheli; Pan, Yanhui; Hu, Ling; Zhao, Zhigang; Chen, Yunxia; Kuang, Jian; Shu, Yi; Qian, Jinhua; Mao, Qibin; Zhang, Jieji; Liu, Yan; Yang, Hong; Yan, Zhaoli; Xie, Weici; Zhang, Qian; Zhang, Ping; Wu, Hongji; Gao, Ling; Jin, Yongjun; Xu, Ning; Xu, Chaoyang; Sun, Xiaohui; Feng, Zhimin; Zhang, Qing; Li, Lin; Ning, Guang; Zhang, Yifei; Cao, Yanan; Wang, Weiqing 分享 收藏 Life's Essential 8 cardiovascular health, cardiovascular-kidney-metabolic syndrome stages, and incident cardiovascular events: a nationwide 10-year prospective cohort study in China生命 Essential 8 心血管健康，心血管-肾脏-代谢综合征分期，以及心血管事件的发生：一项在中国进行的为期10年的全国性前瞻性队列研究Li, Mian; Xu, Min; Ding, Yi; Lin, Hong; Qin, Guijun; Wang, Tiange; Xu, Yu; Chen, Yuhong; Wang, Shuangyuan; Zhao, Zhiyun; Zheng, Jie; Yan, Li; Shi, Lixin; Gao, Zhengnan; Chen, Lulu; Zeng, Tianshu; Hu, Ruying; Ye, Zhen; Yu, Xuefeng; Chen, Gang; Su, Qing; Mu, Yiming; Tang, Xulei; Wan, Qin; Wang, Guixia; Shen, Feixia; Gu, Xuejiang; Luo, Zuojie; Qin, Yingfen; Chen, Li; Hou, Xinguo; Huo, Yanan; Li, Qiang; Qiao, Hong; Zhang, Yinfei; Liu, Chao; Wang, Youmin; Wu, Shengli; Yang, Tao; Deng, Huacong; Zhao, Jiajun; Ning, Guang; Lu, Jieli; Wang, Weiqing; Bi, Yufang 分享 收藏 分享 收藏 Chain effect of lifecourse reproductive characteristics and body fat and muscle on cardiovascular disease in women: a Mendelian randomization study女性生命历程生殖特征、体脂和肌肉对心血管疾病的链式效应：一项孟德尔随机化研究Liu, Dong; Dou, Chun; Ye, Chaojie; Kong, Lijie; Zhu, Zheng; Chen, Mingling; Zheng, Jie; Xu, Min; Xu, Yu; Li, Mian; Zhao, Zhiyun; Lu, Jieli; Chen, Yuhong; Ning, Guang; Wang, Weiqing; Bi, Yufang; Wang, Tiange 分享 收藏 Identifying PDAP1 as a Biological Target on Human Longevity: Integration of Mendelian Randomization, Cohort, and Cell Experiments Validation StudyHou, Tianzhichao; Sha, Zimo; Wang, Qi; Zhu, Yuanyue; Zhu, Zheng; Dai, Huajie; Zhu, Yijie; Wang, Tiange; Li, Mian; Zhao, Zhiyun; Xu, Yu; Lu, Jieli; Zheng, Jie; Ye, Jing; Wang, Weiqing; Ning, Guang; Bi, Yufang; Hu, Weiguo; Xu, Min 分享 收藏 Addition of thoracic radiotherapy to a PD-L1 inhibitor plus chemotherapy regimen delays brain metastasis onset in extensive-stage small cell lung cancer patients without baseline brain metastasis将胸腺放射治疗添加到PD-L1抑制剂联合化疗方案中，可延迟无基线脑转移的广泛期小细胞肺癌患者的脑转移发生时间。Huang, Baiyang; Liu, Senyuan; Wang, Kaiyue; Zhao, Jiarui; Li, Min; Wang, Xingpeng; Wang, Weiqing; Wang, Xiaohan; Yu, Jinming; Meng, Xue 分享 收藏 Single-cell transcriptome-wide Mendelian randomization and colocalization reveals immune-mediated regulatory mechanisms and drug targets for COVID-19单细胞转录组范围孟德尔随机化和共定位揭示了COVID-19的免疫介导调控机制和药物靶点Ying, Hui; Wu, Xueyan; Jia, Xiaojing; Yang, Qianqian; Liu, Haoyu; Zhao, Huiling; Chen, Zhihe; Xu, Min; Wang, Tiange; Li, Mian; Zhao, Zhiyun; Zheng, Ruizhi; Wang, Shuangyuan; Lin, Hong; Xu, Yu; Lu, Jieli; Wang, Weiqing; Ning, Guang; Zheng, Jie; Bi, Yufang 分享 收藏 Shared genetic architecture of type 2 diabetes with muscle mass and function and frailty reveals comorbidity etiology and pleiotropic druggable targetsDou, Chun; Liu, Dong; Kong, Lijie; Chen, Mingling; Ye, Chaojie; Zhu, Zheng; Zheng, Jie; Xu, Min; Xu, Yu; Li, Mian; Zhao, Zhiyun; Lu, Jieli; Chen, Yuhong; Ning, Guang; Wang, Weiqing; Bi, Yufang; Wang, Tiange 分享 收藏 
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