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B

Barton F. Haynes

Duke University School of Medicine
H指数:144
被引数:7.7万
浏览量:0

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Humans and rhesus macaques share maturation pathways of HIV-1 envelope-reactive V3-glycan bnAb lineages

人类和恒河猴共享HIV-1包膜反应性V3-糖基bnAb谱系的成熟途径

Science Translational Medicine
IF14.6
2026-07-080
PRE
Matthew Clark; Hui Li; Mitchell Martin; Tyler D. Evangelous; Sophie M.-C. Gobeil; Madison Berry; Kshitij Wagh; Elena E. Giorgi; Michael P. Hogarty; Chengyan Zhao; Shuyi Wang; Lorie Marchitto; Wenge Ding; Younghoon Park; Juliette Rando; John Carey; Andrew J. Connell; Ashwin N. Skelly; Yue Chen; Seth Rohr; Samantha Balgobin; Chuancang Jiang; Sravani Venkatayogi; Katayoun Mansouri; Robert J. Edwards; Jared Lindenberger; Bhavna Hora; Nicole Doria-Rose; John Mascola; Marit J. van Gils; Rogier W. Sanders; Bette Korber; Beatrice Hahn; Kevin O. Saunders; Priyamvada Acharya; Kevin Wiehe; Barton F. Haynes; George M. Shaw; Wilton B. Williams
Enhanced B cell priming induces broadly neutralizing HIV-1 apex antibodies

增强B细胞初始刺激诱导广泛中和HIV-1顶点抗体

Nature
IF48.5
2026-06-300
PRE
Lorie Marchitto; Kshitij Wagh; Ryan S. Roark; Severin Coleon; Hui Li; Ashwin N. Skelly; Michael P. Hogarty; Rumi Habib; Wenge Ding; Kasirajan Ayyanathan; Weimin Liu; Zizhang Sheng; Yicheng Guo; Joena Bal; Lena M. Smith; Laura L. Sutherland; Younghoon Park; Andrew J. Connell; Frederic Bibollet-Ruche; Emily Lewis; Samantha J. Plante; Macy J. Akeley; Jinery Lora; Chengyan Zhao; John W. Carey; Christian L. Martella; Yingying Li; Mary S. Campion; Melinda G. Lituchy; Rebecca A. Osbaldeston; Colette G. Gordon; Amie Albertus; Justin Su; Chiaki Noguchi; Ying K. Tam; Christopher Barbosa; Bo Liang; Khaled Amereh; Xuduo Li; Agnes A. Walsh; Darrell J. Irvine; Raiees Andrabi; Robert J. Edwards; Edward F. Kreider; Drew Weissman; Lawrence Shapiro; Peter D. Kwong; Bette T. Korber; Barton F. Haynes; Kevin O. Saunders; Beatrice H. Hahn; George M. Shaw
Mechanistic and antigenic boundaries of Henipavirus and Parahenipavirus glycoproteins

亨尼帕病毒和副亨尼帕病毒糖蛋白的机制和抗原边界

Nature Communications
IF15.7
2026-06-190
OAAI
Aaron J. May; Muralikrishna Lella; Jared Lindenberger; Alex Berkman; Ujjwal Kumar; Kejun Liu; Moumita Dutta; Maggie Barr; Rob Parks; Xiaozhi Lu; Madison Berry; Amanda Powell; Amelia G. Thompson; Sravya Sowdamini Nakka; Camila T. França; Xiao Huang; Arpita Mrigwani; Kijun Song; Victor Ilevbare; Salam Sammour; Chan Soo Park; Radha Devkota Adhikari; Priyanka Devkota; Katarzyna Janowska; Yanshun Liu; Garrett Scapellato; Taylor N. Spence; Katayoun Mansouri; Kevin Wiehe; Nancy J. Sullivan; Rosemarie Mason; Robert J. Edwards; Kevin O. Saunders; Barton F. Haynes; Priyamvada Acharya
Induction of broadly neutralizing HIV antibodies by a two-step mechanism informs vaccine design

通过两步机制诱导广谱中和HIV抗体为疫苗设计提供信息

Science
IF45.8
2026-05-070
PRE
Ashwin N. Skelly; Harry B. Gristick; Hui Li; Edem Gavor; Andrew J. Connell; Edward F. Kreider; Lorie Marchitto; Michael P. Hogarty; Maddy L. Newby; Joel D. Allen; Weimin Liu; Anthony P. West; Kasirajan Ayyanathan; Mary S. Campion; Kaitlyn Winters; Colette G. Gordon; Rebecca A. Osbaldeston; Macy J. Akeley; Emily Lewis; Yingying Li; Ajay Singh; Kendra Cruickshank; Younghoon Park; Chengyan Zhao; Xuduo Li; Khaled Amereh; Elizabeth Van Itallie; John W. Carey; Amie Albertus; Andrew T. DeLaitsch; Jennifer R. Keeffe; Melinda G. Lituchy; Agnes A. Walsh; Daniel J. Morris; Rumi Habib; Frederic Bibollet-Ruche; Nitesh Mishra; Gabriel Avillion; Nicholas S. Koranda; Samantha J. Plante; Christian L. Martella; Jinery Lora; Eric J. D. Wang; Mark G. Lewis; Malcolm A. Martin; Michel C. Nussenzweig; Michael S. Seaman; Darrell J. Irvine; Kevin J. Wiehe; Barton F. Haynes; Kshitij Wagh; Bette Korber; Raiees Andrabi; Max Crispin; Drew Weissman; Pamela J. Bjorkman; Beatrice H. Hahn; George M. Shaw
Env-antibody coevolution identifies B cell priming as the principal bottleneck to HIV V2 apex broadly neutralizing antibody development

Env-antibody共进化识别B细胞初始为HIV V2顶点广谱中和抗体发展的主要瓶颈

Science Immunology
IF16.3
2026-02-130
PRE
Rumi Habib; Ryan S. Roark; Hui Li; Andrew Jesse Connell; Michael P. Hogarty; Kshitij Wagh; Shuyi Wang; Lorie Marchitto; Ashwin N. Skelly; John W. Carey; Kirsten J. Sowers; Kasirajan Ayyanathan; Samantha J. Plante; Frederic Bibollet-Ruche; Younghoon Park; Colby J. Agostino; Ajay Singh; Christian L. Martella; Emily Lewis; Juliette M. Rando; Neha Chohan; Jinery Lora; Wenge Ding; Mary S. Campion; Chengyan Zhao; Weimin Liu; Yingying Li; Xuduo Li; Bo Liang; Rohan Roy Chowdhury; Khaled Amereh; Elizabeth Van Itallie; Zizhang Sheng; Amrit R. Ghosh; Katharine J. Bar; Wilton B. Williams; Kevin Wiehe; Kevin O. Saunders; Robert J. Edwards; Derek W. Cain; Mark G. Lewis; Facundo D. Batista; Dennis R. Burton; Raiees Andrabi; Daniel W. Kulp; Barton F. Haynes; Bette Korber; Lawrence Shapiro; Peter D. Kwong; Beatrice H. Hahn; George M. Shaw
ALFQ adjuvanted HIV-1 envelope protein vaccination elicits durable functional antibody and cellular responses in nonhuman primates

ALFQ佐剂HIV-1包膜蛋白疫苗接种在非人灵长类动物中诱导了持久的抗体和细胞免疫应答。

npj Vaccines
IF6.5
2025-12-190
OAAI
Shikha Shrivastava; Joshua M. Carmen; Jiae Kim; Kristina K. Peachman; Shraddha Basu; Ryan Alving; Danielle Nettere; Gautam Kundu; Lauren Yum; Mohammad Arif Rahman; Shalini Jha; Hung V. Trinh; Lorean Rosado; Phuong Nguyen; Elaine Morrison; Isabella Swafford; Kawthar Machmach; Jessica S. Bolton; Adam Yates; Elina Misicka; Zoltan Beck; Simona Mutascio; Ousman Jobe; Michelle Zemil McCrea; Lindsay Wieczorek; Elke S. Bergmann-Leitner; Victoria Polonis; Dominic Paquin-Proulx; Justin Pollara; Gary R. Matyas; Carl R. Alving; Rasmi Thomas; Genoveffa Franchini; Guido Ferrari; Barton F. Haynes; Julie A. Ake; Mangala Rao
Glycan-reactive antibodies isolated from human HIV-1 vaccine trial participants show broad pathogen cross-reactivity

来自人类HIV-1疫苗试验参与者的糖链反应性抗体显示出广泛的病原体交叉反应性

JOURNAL OF VIROLOGY
IF3.8
2025-11-010
PRE
Jamieson, Parker J.; Shen, Xiaoying; Abu-Shmais, Alexandra A.; Wasdin, Perry T.; Janowska, Katarzyna; Edwards, Robert J.; Scapellato, Garrett; Bukenya, Maurice; Bass, Lindsay E.; Richardson, Simone I.; Manamela, Nelia P.; Liu, Shuying; Barr, Maggie; Adams, Lindsey; Paola Velez-Castro, Cristina; Mccarthy, Caitlin; Alexander, Caroline A.; Gillespie, Rebecca A.; Mimms, Jessica; Suryadevara, Naveenchandra; Sornberger, Ty A.; Zost, Seth J.; Parks, Robert; Flaherty, Shelby; Janke, Alexis K.; Howard, Bethany N.; Suresh, Yukthi P.; Ruprecht, Ruth M.; Crowe, James E.; Carnhan, Robert H.; Bailey, Justin R.; Kanekiyo, Masaru; Lingwood, Daniel; Haynes, Barton F.; Moore, Penny L.; Bonami, Rachel H.; Tomaras, Georgia D.; Archarya, Priyamvada; Montefiori, David C.; Kalams, Spyros A.; Lu, Shan; Georgiev, Ivelin S.
Acquisition of quaternary trimer interaction as a key step in the lineage maturation of a broad and potent HIV-1 neutralizing antibody

四聚体三聚体相互作用的形成作为广谱强效HIV-1中和抗体谱系成熟过程中的关键步骤

Structure
IF4.3
2025-05-230
PRE
Qingbo Liu; Ruth J. Parsons; Kevin Wiehe; Robert J. Edwards; Kevin O. Saunders; Peng Zhang; Huiyi Miao; Kedamawit Tilahun; Julia Jones; Yue Chen; Bhavna Hora; Wilton B. Williams; David Easterhoff; Xiao Huang; Katarzyna Janowska; Katayoun Mansouri; Barton F. Haynes; Priyamvada Acharya; Paolo Lusso
Engineering immunogens that select for specific mutations in HIV broadly neutralizing antibodies
NATURE COMMUNICATIONS
IF15.7
2024-11-030
OAAI
Henderson, Rory; Anasti, Kara; Manne, Kartik; Stalls, Victoria; Saunders, Carrie; Bililign, Yishak; Williams, Ashliegh; Bubphamala, Pimthada; Montani, Maya; Kachhap, Sangita; Li, Jingjing; Jaing, Chuancang; Newman, Amanda; Cain, Derek W.; Lu, Xiaozhi; Venkatayogi, Sravani; Berry, Madison; Wagh, Kshitij; Korber, Bette; Saunders, Kevin O.; Tian, Ming; Alt, Fred; Wiehe, Kevin; Acharya, Priyamvada; Alam, S. Munir; Haynes, Barton F.
Comparison of the immunogenicity of mRNA-encoded and protein HIV-1 Env-ferritin nanoparticle designs
JOURNAL OF VIROLOGY
IF3.8
2024-09-171
PRE
Mu, Zekun; Whitley, Jill; Martik, Diana; Sutherland, Laura; Newman, Amanda; Barr, Maggie; Parks, Robert; Wiehe, Kevin; Cain, Derek W.; Hodges, Katrina Z.; Venkatayogi, Sravani; Lee, Esther M.; Smith, Lena; Mansouri, Katayoun; Edwards, Robert J.; Wang, Yunfei; Rountree, Wes; Alameh, Mohamad-Gabriel; Tam, Ying; Barbosa, Christopher; Tomai, Mark; Lewis, Mark G.; Santrai, Sampa; Maughan, Maureen; Tian, Ming; Alt, Frederick W.; Weissman, Drew; Saunders, Kevin O.; Haynes, Barton F.
SARS-CoV-2 Omicron XBB lineage spike structures, conformations, antigenicity, and receptor recognition
MOLECULAR CELL
IF16.6
2024-07-010
OAAI
Zhang, Qianyi E.; Lindenberger, Jared; Parsons, Ruth J.; Thakur, Bhishem; Parks, Rob; Park, Chan Soo; Huang, Xiao; Sammour, Salam; Janowska, Katarzyna; Spence, Taylor N.; Edwards, Robert J.; Martin, Mitchell; Williams, Wilton B.; Gobeil, Sophie; Montefiori, David C.; Korber, Bette; Saunders, Kevin O.; Haynes, Barton F.; Henderson, Rory; Acharya, Priyamvada
Vaccine-mediated protection against Merbecovirus and Sarbecovirus challenge in mice
CELL REPORTS
IF6.9
2023-10-016
OAAI
Martinez, David R.; Schafer, Alexandra; Gavitt, Tyler D.; Mallory, Michael L.; Lee, Esther; Catanzaro, Nicholas J.; Chen, Haiyan; Gully, Kendra; Scobey, Trevor; Korategere, Pooja; Brown, Alecia; Smith, Lena; Parks, Robert; Barr, Maggie; Newman, Amanda; Bowman, Cindy; Powers, John M.; Soderblom, Erik J.; Mansouri, Katayoun; Edwards, Robert J.; Baric, Ralph S.; Haynes, Barton F.; Saunders, Kevin O.
Germline-targeting HIV-1 Env vaccination induces VRC01-class antibodies with rare insertions
CELL REPORTS MEDICINE
IF10.6
2023-04-0115
OAAI
Caniels, Tom G.; Medina-Ramirez, Max; Zhang, Jinsong; Sarkar, Anita; Kumar, Sonu; LaBranche, Alex; Derking, Ronald; Allen, Joel D.; Snitselaar, Jonne L.; Capella-Pujol, Joan; Sanchez, Ivan del Moral; Yasmeen, Anila; Diaz, Marilyn; Aldon, Yoann; Bijl, Tom P. L.; Venkatayogi, Sravani; Beem, Joshua S. Martin; Newman, Amanda; Jiang, Chuancang; Lee, Wen-Hsin; Pater, Maarten; Burger, Judith A.; Breemen, Marielle J. van; Taeye, Steven W. de; Rantalainen, Kimmo; LaBranche, Celia; Saunders, Kevin O.; Montefiori, David; Ozorowski, Gabriel; Ward, Andrew B.; Crispin, Max; Moore, John P.; Klasse, Per Johan; Haynes, Barton F.; Wilson, Ian A.; Wiehe, Kevin; Verkoczy, Laurent; Sanders, Rogier W.
A Germline-Targeting Chimpanzee SIV Envelope Glycoprotein Elicits a New Class of V2-Apex Directed Cross-Neutralizing Antibodies
MBIO
IF4.7
2023-02-284
OAAI
Bibollet-Ruche, Frederic; Russell, Ronnie M. M.; Ding, Wenge; Liu, Weimin; Li, Yingying; Wagh, Kshitij; Wrapp, Daniel; Habib, Rumi; Skelly, Ashwin N. N.; Roark, Ryan S. S.; Sherrill-Mix, Scott; Wang, Shuyi; Rando, Juliette; Lindemuth, Emily; Cruickshank, Kendra; Park, Younghoon; Baum, Rachel; Carey, John W. W.; Connell, Andrew Jesse; Li, Hui; Giorgi, Elena E. E.; Song, Ge S. S.; Ding, Shilei; Finzi, Andres; Newman, Amanda; Hernandez, Giovanna E. E.; Machiele, Emily; Cain, Derek W. W.; Mansouri, Katayoun; Lewis, Mark G. G.; Montefiori, David C. C.; Wiehe, Kevin J. J.; Alam, S. Munir; Teng, I-Ting; Kwong, Peter D. D.; Andrabi, Raiees; Verkoczy, Laurent; Burton, Dennis R. R.; Korber, Bette T. T.; Saunders, Kevin O. O.; Haynes, Barton F. F.; Edwards, Robert J. J.; Shaw, George M. M.; Hahn, Beatrice H. H.

研究方向

暂未获取到该数据
D
David C. Montefiori
H 指数:142论文数:1,160被引数:8.6万
G
Georgia D. Tomaras
H 指数:87论文数:535被引数:2.9万
S
S. Munir Alam
H 指数:73论文数:233被引数:1.9万
H
Hua‐Xin Liao
H 指数:66论文数:218被引数:1.4万
M
M. Anthony Moody
H 指数:73论文数:434被引数:1.6万
K
Kevin O. Saunders
H 指数:50论文数:210被引数:9,686
G
Guido Ferrari
H 指数:70论文数:503被引数:1.8万
R
Robert Parks
H 指数:58论文数:165被引数:1.1万
G
George M. Shaw
H 指数:121论文数:399被引数:5.5万
B
Beatrice H. Hahn
H 指数:140论文数:663被引数:8.1万