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Safety and Efficacy of the Combination Lurbinectedin plus Doxorubicin from a Phase 1b Trial in Patients with Advanced/Metastatic Soft-Tissue Sarcoma 来自晚期/转移性软组织肉瘤患者的1b期试验的Lurbinectedin联合阿霉素的安全性和有效性 Cote, Gregory M.; Haddox, Candace L.; Choy, Edwin; Merriam, Priscilla A.; Mazzola, Emanuele; Venkataraman, Vinayak; Alcindor, Thierry; Wagner, Andrew J.; Demetri, George D.; George, Suzanne 分享 收藏
Afamitresgene autoleucel for advanced synovial sarcoma and myxoid round cell liposarcoma (SPEARHEAD-1): an international, open-label, phase 2 trial Afamitresgene autoleucel用于晚期滑膜肉瘤和粘液样圆形细胞脂肪肉瘤 (SPEARHEAD-1): 一项国际，开放标签，2期试验 D'Angelo, Sandra P.; Araujo, Dejka M.; Razak, Albiruni R. Abdul; Agulnik, Mark; Attia, Steven; Blay, Jean -Yves; Garcia, Irene Carrasco; Charlson, John A.; Choy, Edwin; Demetri, George; Druta, Mihaela; Forcade, Edouard; Ganjoo, Kristen N.; Glod, John; Keedy, Vicki L.; Le Cesne, Axel; Liebner, David A.; Moreno, Victor; Pollack, Seth M.; Schuetze, Scott M.; Schwartz, Gary K.; Strauss, Sandra J.; Tap, William; Thistlethwaite, Fiona; Morales, Claudia Maria Valverde; Wagner, Michael J.; Wilky, Breelyn A.; Mcalpine, Cheryl; Hudson, Laura; Navenot, Jean -Marc; Wang, Tianjiao; Bai, Jane; Rafail, Stavros; Wang, Ruoxi; Sun, Amy; Fernandes, Lilliam; Van Winkle, Erin; Elefant, Erica; Lunt, Colin; Norry, Elliot; Williams, Dennis; Biswas, Swethajit; Van Tine, Brian A. 分享 收藏
Targeting casein kinase 1 alpha (CK1 alpha) and transcriptional CDKs (CDK7/9) in human liposarcomas Liu, Renyan; Solimini, Nicole L.; Bhola, Patrick; Branigan, Timothy B.; Hao, Jie; Wang, Xin; Alharthi, Roshen; Yorsz, Michael; Soni, Shaili; Hu, Cing-siang; Snir-Alkalay, Irit; Gokhale, Prafulla; Letai, Anthony; Ben-Neriah, Yinon Yinon; Demetri, George D.; Shapiro, Geoffrey I. 分享 收藏
Clinical Outcomes Among Immunotherapy-Treated Patients With Primary Cardiac Soft Tissue Sarcomas: A Multicenter Retrospective Study Nassar, Amin H.; El-Am, Edward; Denu, Ryan; Abou Alaiwi, Sarah; El Zarif, Talal; Macaron, Walid; Abdel-Wahab, Noha; Desai, Aakash; Smith, Caleb; Parikh, Kaushal; Abbasi, Muhannad; Farhat, Elias Bou; Williams, James M.; Collins, Jeremy D.; Al-Hader, Ahmad; McKay, Rana R.; Malvar, Carmel; Sabra, Mohamad; Zhong, Caiwei; El Alam, Raquelle; Chehab, Omar; Lima, Joao; Phan, Minh; Pria, Hanna Ferreira Dalla; Trevino, Alexandra; Neilan, Tomas G.; Kwan, Jennifer M.; Ravi, Vinod; Deshpande, Hari; Demetri, George; Choueiri, Toni K.; Naqash, Abdul Rafeh 分享 收藏
Impact of supraphysiologic MDM2 expression on chromatin networks and therapeutic responses in sarcoma 超生理MDM2表达对肉瘤染色质网络和治疗反应的影响 Bevill, Samantha M.; Casani-Galdon, Salvador; El Farran, Chadi A.; Cytrynbaum, Eli G.; Macias, Kevin A.; Oldeman, Sylvie E.; Oliveira, Kayla J.; Moore, Molly M.; Hegazi, Esmat; Adriaens, Carmen; Najm, Fadi J.; Demetri, George D.; Cohen, Sonia; Mullen, John T.; Riggi, Nicolo; Johnstone, Sarah E.; Bernstein, Bradley E. 分享 收藏
Concurrent inhibition of CDK2 adds to the anti-tumour activity of CDK4/6 inhibition in GIST Schaefer, Inga-Marie; Hemming, Matthew L.; Lundberg, Meijun Z.; Serrata, Matthew P.; Goldaracena, Isabel; Liu, Ninning; Yin, Peng; Paulo, Joao A.; Gygi, Steven P.; George, Suzanne; Morgan, Jeffrey A.; Bertagnolli, Monica M.; Sicinska, Ewa T.; Chu, Chen; Zheng, Shanshan; Marino-Enriquez, Adrian; Hornick, Jason L.; Raut, Chandrajit P.; Ou, Wen-Bin; Demetri, George D.; Saka, Sinem K.; Fletcher, Jonathan A. 分享 收藏
Biomarker correlates with response to NY-ESO-1 TCR T cells in patients with synovial sarcoma Gyurdieva, Alexandra; Zajic, Stefan; Chang, Ya-Fang; Houseman, E. Andres; Zhong, Shan; Kim, Jaegil; Nathenson, Michael; Faitg, Thomas; Woessner, Mary; Turner, David C.; Hasan, Aisha N.; Glod, John; Kaplan, Rosandra N.; D'Angelo, Sandra P.; Araujo, Dejka M.; Chow, Warren A.; Druta, Mihaela; Demetri, George D.; Van Tine, Brian A.; Grupp, Stephan A.; Fine, Gregg D.; Eleftheriadou, Ioanna 分享 收藏
Updated Integrated Analysis of the Efficacy and Safety of Entrectinib in Patients With NTRK Fusion-Positive Solid Tumors Demetri, George D.; De Braud, Filippo; Drilon, Alexander; Siena, Salvatore; Patel, Manish R.; Cho, Byoung Chul; Liu, Stephen, V; Ahn, Myung-Ju; Chiu, Chao-Hua; Lin, Jessica J.; Goto, Koichi; Lee, Jeeyun; Bazhenova, Lyudmila; John, Thomas; Fakih, Marwan; Chawla, Sant P.; Dziadziuszko, Rafal; Seto, Takashi; Heinzmann, Sebastian; Pitcher, Bethany; Chen, David; Wilson, Timothy R.; Rolfo, Christian 分享 收藏
E3 ubiquitin ligase Atrogin-1 mediates adaptive resistance to KIT-targeted inhibition in gastrointestinal stromal tumor Garcia-Valverde, Alfonso; Rosell, Jordi; Sayols, Sergi; Gomez-Peregrina, David; Pilco-Janeta, Daniel F.; Olivares-Rivas, Ivan; de Alava, Enrique; Maurel, Joan; Rubio-Casadevall, Jordi; Esteve, Anna; Gut, Marta; Valverde, Claudia; Barretina, Jordi; Carles, Joan; Demetri, George D.; Fletcher, Jonathan A.; Arribas, Joaquin; Serrano, Cesar 分享 收藏
Characteristics and outcomes of patients (pts) with NTRK fusion-positive (NTRK plus ) metastatic/locally advanced (LA) solid tumours receiving non-TRK inhibitor (TRKi) standard of care (SoC), and prognostic value of NTRK fusions in clinical practice Demetri, G. D.; Peters, S.; Hibbar, D. P.; Davies, J.; Maund, S. L.; Veronese, L.; Liu, H.; Humblet, O.; Perez, L. 分享 收藏
Pharmacokinetic-pharmacodynamic guided optimisation of dose and schedule of CGM097, an HDM2 inhibitor, in preclinical and clinical studies Bauer, Sebastian; Demetri, George D.; Halilovic, Ensar; Dummer, Reinhard; Meille, Christophe; Tan, Daniel S. W.; Guerreiro, Nelson; Jullion, Astrid; Ferretti, Stephane; Jeay, Sebastien; Van Bree, Laurence; Hourcade-Potelleret, Florence; Wuerthner, Jens U.; Fabre, Claire; Cassier, Philippe A. 分享 收藏
Patient-reported outcomes from STARTRK-2: a global phase II basket study of entrectinib for ROS1 fusion-positive non-small-cell lung cancer and NTRK fusion-positive solid tumours Paz-Ares, L.; Barlesi, F.; Siena, S.; Ahn, M-J; Drilon, A.; Conley, A.; Rolfo, C.; Wolf, J.; Seto, T.; Doebele, R.; Kapre, A.; Chen, D.; McCallum, S.; Osborne, S.; Demetri, G. 分享 收藏
Ultra-rare sarcomas: A consensus paper from the Connective Tissue Oncology Society community of experts on the incidence threshold and the list of entities Stacchiotti, Silvia; Frezza, Anna Maria; Blay, Jean-Yves; Baldini, Elizabeth H.; Bonvalot, Sylvie; Bovee, Judith V. M. G.; Callegaro, Dario; Casali, Paolo G.; Chiang, RuRu Chun-ju; Demetri, George D.; Demicco, Elisabeth G.; Desai, Jayesh; Eriksson, Mikael; Gelderblom, Hans; George, Suzanne; Gounder, Mrinal M.; Gronchi, Alessandro; Gupta, Abha; Haas, Rick L.; Hayes-Jardon, Andrea; Hohenberger, Peter; Jones, Kevin B.; Jones, Robin L.; Kasper, Bernd; Kawai, Akira; Kirsch, David G.; Kleinerman, Eugene S.; Le Cesne, Axel; Lim, Jiwon; Chirlaque Lopez, Maria Dolores; Maestro, Roberta; Marcos-Gragera, Rafael; Martin-Broto, Javier; Matsuda, Tomohiro; Mir, Olivier; Patel, Shreyaskumar R.; Raut, Chandrajit P.; Razak, Albiruni R. A.; Reed, Damon R.; Rutkowski, Piotr; Sanfilippo, Roberta G.; Sbaraglia, Marta; Schaefer, Inga-Marie; Strauss, Dirk C.; Sundby Hall, Kirsten; Tap, William D.; Thomas, David M.; van der Graaf, Winette T. A.; van Houdt, Winan J.; Visser, Otto; von Mehren, Margaret; Wagner, Andrew J.; Wilky, Breelyn A.; Won, Young-Joo; Fletcher, Christopher D. M.; Dei Tos, Angelo P.; Trama, Annalisa 分享 收藏
FDA Oncology Center of Excellence Project Renewal: Engaging the Oncology Community to Update Product Labeling for Older Oncology Drugs Kluetz, Paul G.; Keegan, Patricia; Demetri, George D.; Thornton, Katherine; Sul, Joohee; Kim, Janice; Katzen, Harvey; Burke, Laurie Beth; Harvey, R. Donald; Alebachew, Elleni; Agrawal, Sundeep; Nair, Abhilasha; Donoghue, Martha; Pierce, William F.; Shord, Stacy S.; Gao, Jennifer J.; Pazdur, Richard 分享 收藏
Identification and Therapeutic Targeting of GPR20, Selectively Expressed in Gastrointestinal Stromal Tumors, with DS-6157a, a First-in-Class Antibody-Drug Conjugate Iida, Kenji; Ahmed, Amr H. Abdelhamid; Nagatsuma, Akiko Kawano; Shibutani, Tomoko; Yasuda, Satoru; Kitamura, Michiko; Hattori, Chiharu; Abe, Manabu; Hasegawa, Jun; Iguchi, Takuma; Karibe, Tsuyoshi; Nakada, Takashi; Inaki, Koichiro; Kamei, Reiko; Abe, Yuki; Nomura, Taisei; Andersen, Jessica L.; Santagata, Sandro; Hemming, Matthew L.; George, Suzanne; Doi, Toshihiko; Ochiai, Atsushi; Demetri, George D.; Agatsuma, Toshinori 分享 收藏
Real-world outcomes of patients with locally advanced or metastatic epithelioid sarcoma Gounder, Mrinal M.; Merriam, Priscilla; Ratan, Ravin; Patel, Shreyaskumar R.; Chugh, Rashmi; Villalobos, Victor M.; Thornton, Mark; Van Tine, Brian A.; Abdelhamid, Amr H.; Whalen, Jennifer; Yang, Jay; Rajarethinam, Anand; Duh, Mei Sheng; Bobbili, Priyanka J.; Huynh, Lynn; Totev, Todor, I; Lax, Angela K.; Agarwal, Shefali; Demetri, George D. 分享 收藏
Diagnosis and management of tropomyosin receptor kinase (TRK) fusion sarcomas: expert recommendations from the World Sarcoma Network Demetri, G. D.; Antonescu, C. R.; Bjerkehagen, B.; Bovee, J. V. M. G.; Boye, K.; Chacon, M.; Dei Tos, A. P.; Desai, J.; Fletcher, J. A.; Gelderblom, H.; George, S.; Gronchi, A.; Haas, R. L.; Hindi, N.; Hohenberger, P.; Joensuu, H.; Jones, R. L.; Judson, I; Kang, Y-K; Kawai, A.; Lazar, A. J.; Le Cesne, A.; Maestro, R.; Maki, R. G.; Martin, J.; Patel, S.; Penault-Llorca, F.; Raut, C. Premanand; Rutkowski, P.; Safwat, A.; Sbaraglia, M.; Schaefer, I-M; Shen, L.; Serrano, C.; Schoffski, P.; Stacchiotti, S.; Sundby Hall, K.; Tap, W. D.; Thomas, D. M.; Trent, J.; Valverde, C.; van der Graaf, W. T. A.; von Mehren, M.; Wagner, A.; Wardelmann, E.; Naito, Y.; Zalcberg, J.; Blay, J-Y 分享 收藏
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