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Tumor break load quantitates structural variant-associated genomic instability with biological and clinical relevance across cancers 肿瘤破碎负荷定量分析了跨癌症中与结构变异相关的基因组不稳定性，具有生物学和临床相关性。 Lakbir, Soufyan; de Wit, Renske; de Bruijn, Ino; Kundra, Ritika; Madupuri, Ramyasree; Gao, Jianjiong; Schultz, Nikolaus; Meijer, Gerrit A.; Heringa, Jaap; Abeln, Sanne 分享 收藏
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High Prevalence of Chromosomal Rearrangements and LINE Retrotranspositions Detected in Formalin-Fixed, Paraffin-Embedded Colorectal Cancer Tissue Rubio-Alarcon, Carmen; Stelloo, Ellen; Vessies, Daan C. L.; Erve, Iris van't; Mekkes, Nienke J.; Swennenhuis, Joost; Lakbir, Soufyan; van Bree, Elisabeth J.; Tijssen, Marianne; Diemen, Pien Delis-van; Lanfermeijer, Mirthe; Linders, Theodora; van den Broek, Daan; Punt, Cornelis J. A.; Heringa, Jaap; Meijer, Gerrit A.; Abeln, Sanne; Feitsma, Harma; Fijneman, Remond J. A. 分享 收藏
Faecal Volatile Organic Compounds to Detect Colorectal Neoplasia in Lynch Syndrome-A Prospective Longitudinal Multicentre Study 粪便挥发性有机化合物可检测Lynch综合征中的结肠直肠肿瘤-一项前瞻性纵向多中心研究 van Liere, Elsa L. S. A.; Ramsoekh, Dewkoemar; Daulton, Emma; Dakkak, Maya; van Lingen, Joris M.; Stewart, Trenton K.; Bosch, Sofie; Carvalho, Beatriz; Dekker, Evelien; Jacobs, Maarten A. J. M.; Koornstra, Jan Jacob; Kuijvenhoven, Johan P.; van Leerdam, Monique E.; de Meij, Tim G. J.; Meijer, Gerrit A.; Spaander, Manon C. W.; Covington, James A.; de Boer, Nanne K. H. 分享 收藏
Genomic and transcriptomic characterization of peritoneal, lung and liver metastases of colorectal carcinoma reveals site-specific differences 结直肠癌腹膜、肺和肝转移的基因组学和转录组学特征揭示了位点特异性差异 Crnovrsanin, N.; Lakbir, S.; de Wit, R.; Ketelaars, S.; Kok, N.; Snaebjornsson, P.; Meijer, G.; Abeln, S.; Fijneman, R. 分享 收藏
Cancer treatment monitoring using cell-free DNA fragmentomes 基于游离DNA片段组的癌症治疗监测 Fijneman, R.; Rinaldi, L.; Skidmore, Z.; Alipanahi, B.; Keefer, L.; Erve, I. van 't; Lumbard, K.; Carey, J.; Chesnick, B.; Cristiano, S.; Dracopoli, N.; Scharpf, R.; Meijer, G.; Leal, A. I. C.; Velculescu, V. 分享 收藏
Early evaluation of the effectiveness and cost-effectiveness of ctDNA-guided selection for adjuvant chemotherapy in stage II colon cancer ctDNA指导的 ⅱ 期结肠癌辅助化疗选择的有效性和成本-效果的早期评价 Kramer, Astrid; Greuter, Marjolein J. E.; Schraa, Suzanna J.; Vink, Geraldine R.; Phallen, Jillian; Velculescu, Victor E.; Meijer, Gerrit A.; van den Broek, Daan; Koopman, Miriam; Roodhart, Jeanine M. L.; Fijneman, Remond J. A.; Retel, Valesca P.; Coupe, Veerle M. H. 分享 收藏
Polyketide synthase positive Escherichia coli one-time measurement in stool is not informative of colorectal cancer risk in a screening setting 在筛查环境中，粪便中聚酮化合物合酶阳性大肠杆菌的一次性测量不能提供结直肠癌风险的信息 de Klaver, Willemijn; de Wit, Meike; Bolijn, Anne; Tijssen, Marianne; Delis-van Diemen, Pien; Lemmens, Margriet; Spaander, Manon C. W.; Dekker, Evelien; van Leerdam, Monique E.; Coupe, Veerle M. H.; van Boxtel, Ruben; Clevers, Hans; Carvalho, Beatriz; Meijer, Gerrit A. 分享 收藏
The impact of DNA structural variants on PRKN gene function and colorectal cancer pathogenesis van Bree, Elisabeth J.; Lakbir, Soufyan; Rubio-Alarcon, Carmen; de Wit, Renske; Bolijn, Anne; Delis-van Diemen, Pien; Tijssen, Marianne; Stelloo, Ellen; Feitsma, Harma; Meijer, Gerrit A.; Carvalho, Beatriz; Abeln, Sanne; Fijneman, Remond J. 分享 收藏
Monitoring treatment response in patients with metastatic colorectal cancer using cfDNA fragmentomics testing: The DOLPHIN trial van Steijn, Denise E.; Fijneman, Remond J.; Vink, Geraldine R.; Roodhart, Jeanine M.; Koopman, Miriam; Lahaye, Max J.; Braat, Manon N. G.; Coupe, Veerle M.; van den Broek, Daan A.; Meijer, Gerrit A.; Wang, Haoyue; Greuter, Marjolein J.; Lissenberg-Witte, Birgit I.; Rinaldi, Lorenzo; Peters, E.; Konicki, Alissa; Dracopoli, Nicholas C.; Kok, Niels F.; Velculescu, Victor E. 分享 收藏
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Clinical validity of post-surgery circulating tumor DNA testing in stage III colon cancer patients treated with adjuvant chemotherapy: The PROVENC3 study Alarcon, Carmen Rubio; Georgiadis, Andrew; Franken, Ingrid A.; Wang, Haoyue; van Nassau, Sietske C.; Schraa, Suzanna J.; van der Kruijssen, Dave E.; van Rooijen, Karlijn; Linders, Theodora C.; Delis-van Diemen, Pien; Alkemade, Maartje; Bolijn, Anne; Tijssen, Marianne; Lemmens, Margriet; Meiqari, Lana; Ketelaars, Steven L.; Mosquera, Adria Closa; van Dongen, Miranda M.; Lanfermeijer, Mirthe; Lissenberg-Witte, Birgit I.; Bosch, Linda J.; Bisschop-Snetselaar, Teunise; Adriaans, Bregje; Greer, Amy; Riley, David; White, James R.; Greco, Christopher; Cox, Liam; Fox, Jesse; Victor, Kaitlin; Leech, Catherine; Angiuoli, Samuel V.; Kok, Niels F.; Punt, Cornelis J.; van den Broek, Daan; Koopman, Miriam; Meijer, Gerrit A.; Velculescu, Victor E.; Roodhart, Jeanine M.; Coupe, Veerle M.; Sausen, Mark; Vink, Geraldine R.; Fijneman, Remond J. 分享 收藏
Comparison of FIT and cell-free DNA analyses for detection of individuals with colorectal cancer in population based screening Wisse, Pieter Henk Abraham; Rubio-Alarcon, Carmen; Schraa, Suzanna J.; Mosquera, Adria C.; Sausen, Mark; Fijneman, Remond J.; Vink, Geraldine R.; de Wit, Meike; Phallen, Jillian; Velculescu, Victor E.; Carvalho, Beatriz; Meijer, Gerrit A. 分享 收藏
Chromatin landscapes of colorectal cancer development and cfDNA fragmentation Vulpescu, Nicholas A.; Foda, Zachariah H.; Wisse, Pieter H.; Medina, Jamie E.; Adleff, Vilmos; Fijneman, Remond J.; Scharpf, Robert B.; Meijer, Gerrit A.; Carvalho, Beatriz; Velculescu, Victor E. 分享 收藏
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