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Sarcoid-like reactions in patients treated with checkpoint inhibitors for advanced solid tumors 接受免疫检查点抑制剂治疗晚期实体瘤患者的类肉瘤样反应 Nykaza, Ian; Murciano-Goroff, Yonina R.; Desilets, Antoine; Harada, Guilherme; Postow, Michael A.; Callahan, Margaret K.; Lee, Chung-Han; Rudin, Charles M.; Kelsen, David Paul; Stadler, Zsofia K.; Wibmer, Andreas G.; Hechtman, Jaclyn F.; Drilon, Alexander; Friedman, Claire F. 分享 收藏
Extracellular vesicles from the lung pro-thrombotic niche drive cancer-associated thrombosis and metastasis via integrin beta 2 肺促血栓形成微环境中的外泌体通过整合素β2驱动肿瘤相关血栓形成和转移 Lucotti, Serena; Ogitani, Yusuke; Kanific, Candia M.; Geri, Jacob; Kim, Young Hun; Gu, Jinghua; Balaji, Uthra; Bojmar, Linda; Shaashua, Lee; Song, Yi; Cioffi, Michele; Lauritzen, Pernille; Joseph, Oveen M.; Asao, Tetsuhiko; Grandgenett, Paul M.; Hollingsworth, Michael A.; Peralta, Christopher; Pagano, Alexandra E.; Molina, Henrik; Lengel, Harry B.; Dunne, Elizabeth G.; Jing, Xiaohong; Schmitter, Madeleine; Borriello, Lucia; Miller, Thomas; Zhang, Haiying; Romin, Yevgeniy; Manova, Katia; Paul, Doru; Remmel, H. Lawrence; O'Reilly, Eileen M.; Janagin, William R.; Kelsen, David; Castellino, Sharon M.; Giulino-Roth, Lisa; Jones, David R.; Condeelis, John S.; Pascual, Virginia; Bussel, James B.; Boudreau, Nancy; Matei, Irina; Entenberg, David; Bromberg, Jacqueline F.; Simeone, Diane M.; Lyden, David 分享 收藏
Phase II trial of Pembrolizumab and OLApaRib (POLAR) maintenance for select patients (pts) with metastatic pancreatic cancer (mPC) with (A) homologous recombination deficiency (HRD), (B) non-core HRD (ncHRD) and (C) exceptional response to platinum II期临床试验，评估Pembrolizumab和OLApaRib（POLAR）用于具有同源重组缺陷（HRD）、非核心同源重组缺陷（ncHRD）以及对铂类药物有例外反应的转移性胰腺癌（mPC）患者的维持治疗。 Park, W.; Connor, C. O'; Chou, J.; Schwartz, C.; Larsen, M.; Varghese, A.; Yu, K.; Balogun, F.; Yang, J.; Katz, S.; Kelsen, D.; Umeda, S.; Bandlamudi, C.; Riaz, N.; Berger, M.; Balachandran, V.; Peer, D.; Capanu, M.; Iacobuzio-Donahue, C.; O'Reilly, E. M. 分享 收藏
Multi-parametric atlas of the pre-metastatic liver for prediction of metastatic outcome in early-stage pancreatic cancer Bojmar, Linda; Zambirinis, Constantinos P.; Hernandez, Jonathan M.; Chakraborty, Jayasree; Shaashua, Lee; Kim, Junbum; Johnson, Kofi Ennu; Hanna, Samer; Askan, Gokce; Burman, Jonas; Ravichandran, Hiranmayi; Zheng, Jian; Jolissaint, Joshua S.; Srouji, Rami; Song, Yi; Choubey, Ankur; Kim, Han Sang; Cioffi, Michele; van Beek, Elke; Sigel, Carlie; Jessurun, Jose; Velasco Riestra, Paulina; Blomstrand, Hakon; Joensson, Carolin; Joensson, Anette; Lauritzen, Pernille; Buehring, Weston; Ararso, Yonathan; Hernandez, Dylanne; Vinagolu-Baur, Jessica P.; Friedman, Madison; Glidden, Caroline; Firmenich, Laetitia; Lieberman, Grace; Mejia, Dianna L.; Nasar, Naaz; Mutvei, Anders P.; Paul, Doru M.; Bram, Yaron; Costa-Silva, Bruno; Basturk, Olca; Boudreau, Nancy; Zhang, Haiying; Matei, Irina R.; Hoshino, Ayuko; Kelsen, David; Sagi, Irit; Scherz, Avigdor; Scherz-Shouval, Ruth; Yarden, Yosef; Oren, Moshe; Egeblad, Mikala; Lewis, Jason S.; Keshari, Kayvan; Grandgenett, Paul M.; Hollingsworth, Michael A.; Rajasekhar, Vinagolu K.; Healey, John H.; Bjoernsson, Bergthor; Simeone, Diane M.; Tuveson, David A.; Iacobuzio-Donahue, Christine A.; Bromberg, Jaqueline; Vincent, C. Theresa; O'Reilly, Eileen M.; DeMatteo, Ronald P.; Balachandran, Vinod P.; D'Angelica, Michael I.; Kingham, T. Peter; Allen, Peter J.; Simpson, Amber L.; Elemento, Olivier; Sandstroem, Per; Schwartz, Robert E.; Jarnagin, William R.; Lyden, David 分享 收藏
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Clinical and molecular characterization of Lynch syndrome-associated pancreas adenocarcinoma (PDAC) Harrold, Emily; O'Connor, Catherine A.; Lin, David; Gazzo, Andrea; Walch, Henry; Ranganathan, Megha; Catchings, Amanda; Kane, Sarah; Keane, Fergus; Thurtle-Schmidt, Deborah M.; Balogun, Fiyinfolu; Varghese, Anna; Yu, Kenneth; Kelsen, David; Latham, Alicia; Weigelt, Britta; Park, Wungki; Stadler, Zsofia; O'Reilly, Eileen M. 分享 收藏
Clinico-genomic characterization of N=2,460 pancreatic adenocarcinoma identifies KRASMUT dosage as prognostic of overall survival across disease stages Varghese, Anna M.; Perry, Maria A.; Muldoon, Daniel; Nandakumar, Subhiksha; Erakky, Amanda; Nguyen, Bastien; Zucker, Amanda; Ozkan, Hulya Sahin; Basturk, Olca; Chakravarty, Debyani; Kelsen, David P.; Park, Wungki; Yu, Kenneth H.; Wei, Alice C.; Schultz, Nikolaus; Berger, Michael F.; Iacobuzio-Donahue, Christine; Bandlamudi, Chaitanya; O'Reilly, Eileen M. 分享 收藏
Deep genomic and single cell molecular profiles define immunogenic pancreatic cancer Park, Wungki; Umeda, Shigeaki; O'Connor, Catherine; Zhang, Haochen; Sharma, Roshan; Richards, Allison; Zhu, Yingjie; Karnoub, Elias-Ramzey; Pei, Xin; Varghese, Anna M.; Soares, Kevin; Sanchez, Alejandro Jimenez; Sahin, Hulya Ozkan; Yu, Kenneth; Balachandran, Vinod P.; Chou, Joanne; Keane, Fergus; Kelsen, David; Basturk, Olca; Bandlamudi, Chaitanya; Capanu, Marinela; Nawy, Tal; Berger, Michael; Chaligne, Ronan; Abou-Alfa, Ghassan; Reis-Filho, Jorge S.; Riaz, Nadeem; Pe'er, Dana; Iacobuzio-Donahue, Christine A.; O'Reilly, Eileen M. 分享 收藏
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A novel approach to convert non-resectable pancreatic cancer with major artery involvement using endovascular activation of Padeliporfin by vascular-targeted photodynamic therapy Preise, Dina; Cohen, Yaniv; Alpert, Genia; Sacks, Zachary; Yechezkel, Tamar; Kudinova, Natalia; Morag, Eyal; Willenz, Ehud; Rothman, Julia; Brook, Keren; Krasnopolskaya, Inna; Agemy, Lilach; Zilber, Sofia; Yarmohammadi, Hooman; Kelsen, David; Perry, David; Scherz, Avigdor 分享 收藏
Integrated clinical and genomic analysis identifies driver events and molecular evolution of colitis-associated cancers Chatila, Walid K.; Walch, Henry; Hechtman, Jaclyn F.; Moyer, Sydney M.; Sgambati, Valeria; Faleck, David M.; Srivastava, Amitabh; Tang, Laura; Benhamida, Jamal; Ismailgeci, Dorina; Campos, Carl; Wu, Fan; Chang, Qing; Vakiani, Efsevia; de Stanchina, Elisa; Weiser, Martin R.; Widmar, Maria; Yantiss, Rhonda K.; Shah, Manish A.; Bass, Adam J.; Stadler, Zsofia K.; Katz, Lior H.; Mellinghoff, Ingo K.; Sethi, Nilay S.; Schultz, Nikolaus; Ganesh, Karuna; Kelsen, David; Yaeger, Rona 分享 收藏
Perioperative liver biopsy captures features of the liver pre-metastatic niche and predicts metastatic outcome after pancreatic cancer resection Bojmar, Linda; Zambirinis, Constantinos P.; Hernandez, Jonathan; Chakraborty, Jayasree; Hanna, Samer; Simeone, Diane; Kelsen, David; Zhang, Haiying; Matei, Irina R.; Sandstrom, Per; Schwartz, Robert; Jarnagin, William R.; Lyden, David 分享 收藏
BRCA mutational status shapes the stromal microenvironment of pancreatic cancer linking clusterin expression in cancer associated fibroblasts with HSF1 signaling BRCA突变状态塑造了胰腺癌的基质微环境，将癌症相关成纤维细胞中的簇蛋白表达与HSF1信号联系起来 Shaashua, Lee; Ben-Shmuel, Aviad; Pevsner-Fischer, Meirav; Friedman, Gil; Levi-Galibov, Oshrat; Nandakumar, Subhiksha; Barki, Debra; Nevo, Reinat; Brown, Lauren E.; Zhang, Wenhan; Stein, Yaniv; Lior, Chen; Kim, Han Sang; Bojmar, Linda; Jarnagin, William R.; Lecomte, Nicolas; Mayer, Shimrit; Stok, Roni; Bishara, Hend; Hamodi, Rawand; Levy-Lahad, Ephrat; Golan, Talia; Porco, John A., Jr.; Iacobuzio-Donahue, Christine A.; Schultz, Nikolaus; Tuveson, David A.; Lyden, David; Kelsen, David; Scherz-Shouval, Ruth 分享 收藏
Circulating tumor and invasive cell expression profiling predicts effective therapy in pancreatic cancer Yu, Kenneth H.; Park, Jennifer; Mittal, Avni; Abou-Alfa, Ghassan K.; El Dika, Imane; Epstein, Andrew S.; Ilson, David H.; Kelsen, David P.; Ku, Geoffrey Y.; Li, Jia; Park, Wungki; Varghese, Anna M.; Chou, Joanne F-L; Capanu, Marinela; Cooper, Brandon; Bartlett, Andrew; McCarthy, Devan; Sangar, Vineet; McCarthy, Brian; O'Reilly, Eileen M. 分享 收藏
PD-L1 expression and overall survival in Asian and western patients with gastric cancer 亚洲和西方胃癌患者的PD-L1表达和总生存率 Rha, Sun Young; Ku, Geoffrey Y.; Kim, Hyo Song; Chung, Hyun Cheol; Amlashi, Fatemeh Ghazanfari; Maru, Dipen Maheshbhai; Fein, Carly A.; Tang, Laura H.; Zhou, Wei; Wu, Ting; Peter, Senaka A.; Kelsen, David P.; Ajani, Jaffer A. 分享 收藏
Different hotspot p53 mutants exert distinct phenotypes and predict outcome of colorectal cancer patients Hassin, Ori; Nataraj, Nishanth Belugali; Shreberk-Shaked, Michal; Aylon, Yael; Yaeger, Rona; Fontemaggi, Giulia; Mukherjee, Saptaparna; Maddalena, Martino; Avioz, Adi; Iancu, Ortal; Mallel, Giuseppe; Gershoni, Anat; Grosheva, Inna; Feldmesser, Ester; Ben-Dor, Shifra; Golani, Ofra; Hendel, Ayal; Blandino, Giovanni; Kelsen, David; Yarden, Yosef; Oren, Moshe 分享 收藏
Pancreas cancer and BRCA: A critical subset of patients with improving therapeutic outcomes Momtaz, Parisa; O'Connor, Catherine A.; Chou, Joanne F.; Capanu, Marinela; Park, Wungki; Bandlamudi, Chaitanya; Berger, Michael F.; Kelsen, David P.; Suehnholz, Sarah P.; Chakravarty, Debyani; Yu, Kenneth H.; Varghese, Anna M.; Zervoudakis, Alice; Li, Jia; Ku, Geoffrey Y.; Park, Jennifer S.; Shcherba, Marina; Harding, James J.; Goldberg, Zoe; Abou-Alfa, Ghassan K.; Salo-Mullen, Erin E.; Stadler, Zsofia K.; Iacobuzio-Donahue, Christine A.; O'Reilly, Eileen M. 分享 收藏
Early-Onset Pancreas Cancer: Clinical Descriptors, Genomics, and Outcomes Varghese, Anna M.; Singh, Isha; Singh, Rituraj; Kunte, Siddharth; Chou, Joanne F.; Capanu, Marinela; Wong, Winston; Lowery, Maeve A.; Stadler, Zsofia K.; Salo-Mullen, Erin; Saadat, Lily, V; Wei, Alice C.; Reyngold, Marsha; Basturk, Olca; Benayed, Ryma; Mandelker, Diana; Iacobuzio-Donahue, Christine A.; Kelsen, David P.; Park, Wungki; Yu, Kenneth H.; O'Reilly, Eileen M. 分享 收藏
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