Michael M. Gottesman - Publications, H-index & Citations

Michael M. Gottesman

national institutes of health

107H指数

698论文数

6.5W被引数

收录论文 144

发表时间

Cisplatin resistance in an ovarian cancer model is mediated by microtubule dynamics regulator TPPP3 in synergy with tubulin code rewiring 顺铂耐药性在卵巢癌模型中由微管动力学调节剂TPPP3与微管代码重编程协同介导

Cell Reports

IF6.9

2026-06-04

OAAI

Sachi Horibata; Kishore K. Mahalingan; Ruchi Patel; Yu Fan; Jordan M. Hotz; Adriana Ponton-Almodovar; Keith MacRenaris; Yan Li; Daoud Meerzaman; Michael M. Gottesman; Antonina Roll-Mecak

Abcb5-deficient mice show a subtle, pleiotropic phenotype indicating a role for this transporter in intermediary metabolism ABCB5缺陷小鼠表现出一种细微的、多效性的表型，表明该转运蛋白在中间代谢中发挥作用。

iScience

IF4.1

2025-09-20

OAAI

Jean-Pierre Gillet; Louise Gerard; Wilfred Vieira; Marie Fourrez; Florence Gaudray; Birgit Rathkolb; Jan Rozman; Tanja Klein-Rodewald; Lore Becker; Antonio Aguilar-Pimentel; Marion Horsch; Nadine Spielmann; Cornelia Prehn; Benoît Bihin; Johannes Beckers; Helmut Fuchs; Valérie Gailus-Durner; Martin Hrabe de Angelis; Eileen Southon; Lino Tessarollo; Di Xia; Michael M. Gottesman

Exploiting the therapeutic vulnerability of IDH-mutant gliomas with zotiraciclib 利用Zotiraciclib靶向IDH突变型胶质瘤的治疗易感性

ISCIENCE

IF4.1

2025-04-01

OAAI

Pang, Ying; Li, Qi; Sergi, Zach; Yu, Guangyang; Kim, Olga; Lu, Peng; Chan, Marina; Sang, Xueyu; Wang, Herui; Ranjan, Alice; Robey, Robert W.; Soheilian, Ferri; Tran, Bao; Nunez, Felipe J.; Zhang, Meili; Song, Hua; Zhang, Wei; Davis, Dionne; Gilbert, Mark R.; Gottesman, Michael M.; Liu, Zhenggang; Thomas, Craig J.; Castro, Maria G.; Gujral, Taranjit S.; Wu, Jing

Abcg2a is the functional homolog of human ABCG2 expressed at the zebrafish blood-brain barrier (vol 21,27,2024)

FLUIDS AND BARRIERS OF THE CNS

IF6.2

2025-01-03

OAAI

Thomas, Joanna R.; Frye, William J. E.; Robey, Robert W.; Warner, Andrew C.; Butcher, Donna; Matta, Jennifer L.; Morgan, Tamara C.; Edmondson, Elijah F.; Salazar, Paula B.; Ambudkar, Suresh V.; Gottesman, Michael M.

Identification of NanoLuciferase Substrates Transported by Human ABCB1 and ABCG2 and Their Zebrafish Homologs at the Blood-Brain Barrier

MOLECULAR PHARMACOLOGY

IF3

2024-12-01

PREAI

Quinlan, John A.; Sabbineni, Sashank; Robey, Robert W.; Lipsey, Crystal C.; Inglut, Collin T.; Thomas, Joanna R.; Walker, Joel R.; Zhou, Wenhui; Huang, Huang-Chiao; Fischell, Michael M. Gottesman

TARGETING MITOCHONDRIAL PROTEASE IN DIFFUSE GLIOMAS

NEURO-ONCOLOGY

IF13.4

2024-11-11

PREAI

Kim, Olga; Sergi, Zach; Yu, Guangyang; Li, Qi; Lu, Peng; Hsia, Ru-Ching; Robey, Robert; Chari, Raj; Wang, Herui; Tran, Bao; Andresson, Thorkell; Gottesman, Michael; Liu, Zhenggang; Graves, Lee; Iwanowicz, Edwin; Wu, Jing

Self-Assembled Verteporfin Nanoparticles for Photodynamic and Light-Independent Therapy in Glioblastoma 自组装versporfin纳米颗粒用于胶质母细胞瘤的光动力和不依赖光的治疗

ADVANCED NANOBIOMED RESEARCH

IF4.4

2024-09-28

OAAI

Quinlan, John A.; Baumiller, Kaylin; Gaur, Anandita; Chiou, Wen-An; Robey, Robert W.; Gottesman, Michael M.; Huang, Huang-Chiao

A whole-genome CRISPR screen identifies the spindle accessory checkpoint as a locus of nab-paclitaxel resistance in a pancreatic cancer cell line

SCIENTIFIC REPORTS

IF3.9

2024-07-10

OAAI

Mondal, Priya; Alyateem, George; Mitchell, Allison V.; Gottesman, Michael M.

Ibrutinib disrupts blood-tumor barrier integrity and prolongs survival in rodent glioma model

ACTA NEUROPATHOLOGICA COMMUNICATIONS

IF5.7

2024-04-08

OAAI

Lim, Sanghee; Kwak, Minhye; Kang, Jeonghan; Cesaire, Melissa; Tang, Kayen; Robey, Robert W.; Frye, William J. E.; Karim, Baktiar; Butcher, Donna; Lizak, Martin J.; Dalmage, Mahalia; Foster, Brandon; Nuechterlein, Nicholas; Eberhart, Charles; Cimino, Patrick J.; Gottesman, Michael M.; Jackson, Sadhana

Abcg2a is the functional homolog of human ABCG2 expressed at the zebrafish blood-brain barrier

FLUIDS AND BARRIERS OF THE CNS

IF6.2

2024-03-15

OAAI

Carrier-Free, Amorphous Verteporfin Nanodrug for Enhanced Photodynamic Cancer Therapy and Brain Drug Delivery 无载体，无定形的vivaporfin纳米药物，用于增强光动力癌症治疗和脑药物递送

ADVANCED SCIENCE

IF14.1

2024-03-06

OAAI

Quinlan, John A.; Inglut, Collin T.; Srivastava, Payal; Rahman, Idrisa; Stabile, Jillian; Gaitan, Brandon; Del Valle, Carla Arnau; Baumiller, Kaylin; Gaur, Anandita; Chiou, Wen-An; Karim, Baktiar; Connolly, Nina; Robey, Robert W.; Woodworth, Graeme F.; Gottesman, Michael M.; Huang, Huang-Chiao

Identification of two novel heterodimeric ABC transporters in melanoma: ABCB5β/B6 and ABCB5β/B9

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2024-02-01

OAAI

Gerard, Louise; Duvivier, Laurent; Fourrez, Marie; Salazar, Paula; Sprimont, Lindsay; Xia, Di; Ambudkar, Suresh, V; Gottesman, Michael M.; Gillet, Jean-Pierre

Progress in characterizing ABC multidrug transporters in zebrafish

DRUG RESISTANCE UPDATES

IF21.7

2024-01-01

PREAI

Thomas, Joanna R.; Frye, William J. E.; Robey, Robert W.; Gottesman, Michael M.

The Methyltransferases METTL7A and METTL7B Confer Resistance to Thiol-Based Histone Deacetylase Inhibitors 甲基转移酶METTL7A和METTL7B赋予对基于硫醇的组蛋白脱乙酰酶抑制剂的抗性

MOLECULAR CANCER THERAPEUTICS

IF5.5

2023-12-27

OAAI

Robey, Robert W.; Fitzsimmons, Christina M.; Guiblet, Wilfried M.; Frye, William J. E.; Dalmasy, Jose M. Gonzalez; Wang, Li; Russell, Drake A.; Huff, Lyn M.; Perciaccante, Andrew J.; Ali-Rahmani, Fatima; Lipsey, Crystal C.; Wade, Heidi M.; Mitchell, Allison V.; Maligireddy, Siddhardha S.; Terrero, David; Butcher, Donna; Edmondson, Elijah F.; Jenkins, Lisa M.; Nikitina, Tatiana; Zhurkin, Victor B.; Tiwari, Amit K.; Piscopio, Anthony D.; Totah, Rheem A.; Bates, Susan E.; Arda, H. Efsun; Gottesman, Michael M.; Batista, Pedro J.

Combined inhibition of topoisomerase I and poly(ADP-ribose) polymerase: A synergistic therapeutic strategy for glioblastoma with phosphatase and tensin homolog deficiency

NEURO-ONCOLOGY ADVANCES

IF4.1

2023-08-21

OAAI

Kim, Olga; Butler, Madison; Sergi, Zach; Robey, Robert W.; Zhang, Meili; Chari, Raj; Pang, Ying; Yu, Guangyang; Zhang, Wei; Song, Hua; Davis, Dionne; Hawley, Robert G.; Wen, Xinyu; Wang, Herui; Quezado, Martha; Tran, Bao; Merchant, Mythili; Ranjan, Alice; Furnari, Frank B.; Khan, Javed; Gilbert, Mark R.; Ryan Miller, Christopher; Gottesman, Michael M.; Pommier, Yves; Wu, Jing

IBRUTINIB DISRUPTS BLOOD-TUMOR BARRIER INTEGRITY TO ENHANCE CNS DRUG DELIVERY AND RODENT GLIOMA MODEL SURVIVAL

NEURO-ONCOLOGY

IF13.4

2023-06-12

OAAI

Lim, Sanghee; Kwak, Minhye; Tang, Kayen; Cesaire, Melissa; Robey, Robert; Gottesman, Michael; Jackson, Sadhana

Use of CRISPR-based screens to identify mechanisms of chemotherapy resistance

CANCER GENE THERAPY

IF5

2023-04-07

OAAI

Alyateem, George; Wade, Heidi M.; Bickert, Aaron A.; Lipsey, Crystal C.; Mondal, Priya; Smith, MacKinzie D.; Labib, Rania M.; Mock, Beverly A.; Robey, Robert W.; Gottesman, Michael M.

Characterization and tissue localization of zebrafish homologs of the human ABCB1 multidrug transporter

SCIENTIFIC REPORTS

IF3.9

2021-12-17

OAAI

Robey, Robert W.; Robinson, Andrea N.; Ali-Rahmani, Fatima; Huff, Lyn M.; Lusvarghi, Sabrina; Vahedi, Shahrooz; Hotz, Jordan M.; Warner, Andrew C.; Butcher, Donna; Matta, Jennifer; Edmondson, Elijah F.; Lee, Tobie D.; Roth, Jacob S.; Lee, Olivia W.; Shen, Min; Tanner, Kandice; Hall, Matthew D.; Ambudkar, Suresh, V; Gottesman, Michael M.

Dual Inhibition of Histone Deacetylases and the Mechanistic Target of Rapamycin Promotes Apoptosis in Cell Line Models of Uveal Melanoma

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

IF4.7

2021-09-17

OAAI

Patel, Ruchi P.; Thomas, Joanna R.; Curt, Katherine M.; Fitzsimmons, Christina M.; Batista, Pedro J.; Bates, Susan E.; Gottesman, Michael M.; Robey, Robert W.

Reversing the direction of drug transport mediated by the human multidrug transporter P-glycoprotein 逆转人多药转运蛋白P-糖蛋白介导的药物转运方向

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-11-09

OAAI

Sajid, Andaleeb; Lusvarghi, Sabrina; Murakami, Megumi; Chufan, Eduardo E.; Abel, Biebele; Gottesman, Michael M.; Durell, Stewart R.; Ambudkar, Suresh, V

研究方向