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Biomarkers of success of anti-PD-(L)1 immunotherapy for non-small cell lung cancer derived from RNA- and whole-exome sequencing: results of a prospective observational study on a cohort of 85 patients Poddubskaya, Elena; Suntsova, Maria; Lyadova, Marina; Luppov, Daniil; Guryanova, Anastasia; Lyadov, Vladimir; Garazha, Andrew; Sorokin, Maksim; Semenova, Anna; Shatalov, Vitaly; Biakhova, Maria; Simonov, Alexander; Moisseev, Aleksey; Buzdin, Anton 分享 收藏
Bioinformatic and clinical experimental assay uncovers resistance and susceptibility mechanisms of human glioblastomas to temozolomide and identifies new combined and individual survival biomarkers outperforming MGMT promoter methylation Modestov, Alexander; Zolotovskaia, Marianna; Suntsova, Maria; Zakharova, Galina; Seryakov, Aleksander; Jovcevska, Ivana; Mlakar, Jernej; Poddubskaya, Elena; Moisseev, Aleksey; Vykhodtsev, Grigory; Roumiantsev, Sergey; Sorokin, Maksim; Tkachev, Victor; Simonov, Aleksander; Buzdin, Anton 分享 收藏
Tislelizumab plus chemotherapy versus placebo plus chemotherapy as first line treatment for advanced gastric or gastro-oesophageal junction adenocarcinoma: RATIONALE-305 randomised, double blind, phase 3 trial Tislelizumab加化疗与安慰剂加化疗作为晚期胃或胃食管交界处腺癌的一线治疗: 原理305的随机，双盲，3期试验 Qiu, Miao-Zhen; Oh, Do-Youn; Kato, Ken; Arkenau, Tobias; Tabernero, Josep; Correa, Marcia Cruz; Zimina, Anastasia, V; Bai, Yuxian; Shi, Jianhua; Lee, Keun-Wook; Wang, Jufeng; Poddubskaya, Elena; Pan, Hongming; Rha, Sun Young; Zhang, Ruixing; Hirano, Hidekazu; Spigel, David; Yamaguchi, Kensei; Chao, Yee; Wyrwicz, Lucjan; Disel, Umut; Cid, Roberto Pazo; Fornaro, Lorenzo; Evesque, Ludovic; Wang, Hongwei; Xu, Yaling; Li, Jiang; Sheng, Tao; Yang, Silu; Li, Liyun; Moehler, Markus; Xu, Rui-Hua 分享 收藏
Datopotamab deruxtecan (Dato-DXd) vs docetaxel in previously treated advanced/metastatic (adv/met) non-small cell lung cancer (NSCLC): Results of the randomized phase III study TROPION-Lung01 Ahn, M-J.; Lisberg, A. E.; Paz-Ares, L.; Cornelissen, R.; Girard, N.; Pons-Tostivint, E.; Vicente Baz, D.; Sugawara, S.; Cobo Dols, M.; Perol, M.; Mascaux, C.; Poddubskaya, E.; Kitazono, S.; Hayashi, H.; Sands, J.; Hall, R.; Zhang, Y.; Zebger-Gong, H.; Uema, D.; Okamoto, I. 分享 收藏
Datopotamab deruxtecan (Dato-DXd) vs docetaxel in previously treated advanced/metastatic (adv/met) non-small cell lung cancer (NSCLC): Results of the randomized phase III study TROPION-Lung01 Ahn, M. J.; Lisberg, A.; Paz-Ares, L.; Cornelissen, R.; Girard, N.; Pons-Tostivint, E.; Baz, D. Vicente; Sugawara, S.; Dols, M. Cobo; Perol, M.; Mascaux, C.; Poddubskaya, E.; Kitazono, S.; Hayashi, H.; Sands, J.; Hall, R.; Zhang, Y.; Zebger-Gong, H.; Uema, D.; Okamoto, I. 分享 收藏
Human Blood Serum Can Diminish EGFR-Targeted Inhibition of Squamous Carcinoma Cell Growth through Reactivation of MAPK and EGFR Pathways Kamashev, Dmitri; Shaban, Nina; Lebedev, Timofey; Prassolov, Vladimir; Suntsova, Maria; Raevskiy, Mikhail; Gaifullin, Nurshat; Sekacheva, Marina; Garazha, Andrew; Poddubskaya, Elena; Sorokin, Maksim; Buzdin, Anton 分享 收藏
A phase II open-label trial of avelumab plus axitinib in previously treated non-small-cell lung cancer or treatment-naive, cisplatin-ineligible urothelial cancer Galffy, G.; Lugowska, I.; Poddubskaya, E., V; Cho, B. C.; Ahn, M. -J.; Han, J. -Y.; Su, W. -C.; Hauke, R. J.; Dyar, S. H.; Lee, D. H.; Serwatowski, P.; Estelles, D. L.; Holden, V. R.; Kim, Y. J.; Vladimirov, V.; Horvath, Z.; Ghose, A.; Goldman, A.; di Pietro, A.; Wang, J.; Murphy, D. A.; Alhadab, A.; Laskov, M. 分享 收藏
Pan-cancer antagonistic inhibition pattern of ATM-driven G2/M checkpoint pathway vs other DNA repair pathways Zolotovskaia, Marianna A.; Modestov, Alexander A.; V. Suntsova, Maria; Rachkova, Anastasia A.; V. Koroleva, Elena; V. Poddubskaya, Elena; Sekacheva, Marina I.; Tkachev, Victor S.; V. Garazha, Andrew; Glusker, Alexander A.; Seryakov, Aleksander P.; Vladimirova, Uliana S.; Rumiantsev, Pavel O.; Moisseev, Aleksey A.; Zharkov, Dmitry O.; V. Kuzmin, Denis; Zhao, Xiaowen; Prassolov, Vladimir S.; V. Shegay, Petr; Li, Xinmin; Steinbichler, Teresa B.; Kim, Ella; Sorokin, Maxim I.; Wang, Ye; Buzdin, Anton A. 分享 收藏
First-line nivolumab plus ipilimumab for metastatic non-small cell lung cancer, including patients with ECOG performance status 2 and other special populations: CheckMate 817 一线nivolumab联合ipilimumab治疗转移性非小细胞肺癌，包括ECOG表现状态2和其他特殊人群的患者: CheckMate 817 Ready, Neal E.; Audigier-Valette, Clarisse; Goldman, Jonathan W.; Felip, Enriqueta; Ciuleanu, Tudor-Eliade; Campelo, Maria Rosario Garcia; Jao, Kevin; Barlesi, Fabrice; Bordenave, Stephanie; Rijavec, Erika; Urban, Laszlo; Aucoin, Jean-Sebastien; Zannori, Cristina; Vermaelen, Karim; Frontera, Osvaldo Aren; Fontecedro, Alessandra Curioni; Sanchez-Gastaldo, Amparo; Juan-Vidal, Oscar; Linardou, Helena; Poddubskaya, Elena; Spigel, David R.; Ahmed, Samreen; Maio, Michele; Li, Sunney; Chang, Han; Fiore, Joseph; Acevedo, Angelic; Paz-Ares, Luis 分享 收藏
Personalized targeted therapy prescription in colorectal cancer using algorithmic analysis of RNA sequencing data Sorokin, Maxim; Zolotovskaia, Marianna; Nikitin, Daniil; Suntsova, Maria; Poddubskaya, Elena; Glusker, Alexander; Garazha, Andrew; Moisseev, Alexey; Li, Xinmin; Sekacheva, Marina; Naskhletashvili, David; Seryakov, Alexander; Wang, Ye; Buzdin, Anton 分享 收藏
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Experimental and Meta-Analytic Validation of RNA Sequencing Signatures for Predicting Status of Microsatellite Instability Sorokin, Maksim; Rabushko, Elizaveta; Efimov, Victor; Poddubskaya, Elena; Sekacheva, Marina; Simonov, Alexander; Nikitin, Daniil; Drobyshev, Aleksey; Suntsova, Maria; Buzdin, Anton 分享 收藏
RNA Sequencing Data for FFPE Tumor Blocks Can Be Used for Robust Estimation of Tumor Mutation Burden in Individual Biosamples Sorokin, Maxim; Gorelyshev, Alexander; Efimov, Victor; Zotova, Evgenia; Zolotovskaia, Marianna; Rabushko, Elizaveta; Kuzmin, Denis; Seryakov, Alexander; Kamashev, Dmitry; Li, Xinmin; Poddubskaya, Elena; Suntsova, Maria; Buzdin, Anton 分享 收藏
Trial comparing the safety, efficacy and immunogenicity of trastuzumab biosimilar candidate (TX05) with originator trastuzumab in HER2+early breast cancer Krivorotko, P.; Manikhas, A.; Moiseenko, F.; Poddubskaya, E.; Neciosup, S. P.; Gopichand, M.; Osynskyi, D.; Haynes, T.; Lai, J.; Mills, B. J. 分享 收藏
Efficacy, Safety and Immunogenicity of MB02 (Bevacizumab Biosimilar) versus Reference Bevacizumab in Advanced Non-Small Cell Lung Cancer: A Randomized, Double-Blind, Phase III Study (STELLA) Trukhin, Dmytro; Poddubskaya, Elena; Andric, Zoran; Makharadze, Tamta; Bellala, Ravi Shankar; Charoentum, Chaiyut; Yanez Ruiz, Eduardo P.; Fulop, Andrea; Ali, Irfhan Ali Hyder; Syrigos, Kostas; Katgi, Nuran; Lopez Chuken, Yamil Alonso; Rumyana, Ilieva; Reyes-Igama, Jasmin; Costamilan, Rita de Cassia; Del Campo Garcia, Ana; Florez, Amalia; Paravisini, Alexandra; Millan, Susana 分享 收藏
Abnormal promoter DNA hypermethylation of the integrin, nidogen, and dystroglycan genes in breast cancer Strelnikov, Vladimir V.; Kuznetsova, Ekaterina B.; Tanas, Alexander S.; Rudenko, Viktoria V.; Kalinkin, Alexey, I; Poddubskaya, Elena, V; Kekeeva, Tatiana, V; Chesnokova, Galina G.; Trotsenko, Ivan D.; Larin, Sergey S.; Kutsev, Sergey, I; Zaletaev, Dmitry, V; Nemtsova, Marina, V; Simonova, Olga A. 分享 收藏
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