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Patrick Doherty

university of london

69H指数
218论文数
1.6W被引数
收录论文 51
发表时间
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A Single Domain Shark Antibody Targeting the Transferrin Receptor 1 Delivers a TrkB Agonist Antibody to the Brain and Provides Full Neuroprotection in a Mouse Model of Parkinson's Disease靶向转铁蛋白受体1的单域鲨鱼抗体将TrkB激动剂抗体递送至大脑，并在帕金森病小鼠模型中提供完全的神经保护
errPHARMACEUTICS
IF5.5
err2022-06-24
err20
errOAAI
errClarke, Emily; Stocki, Pawel; Sinclair, Elizabeth H.; Gauhar, Aziz; Fletcher, Edward J. R.; Krawczun-Rygmaczewska, Alicja; Duty, Susan; Walsh, Frank S.; Doherty, Patrick; Rutkowski, Julia Lynn
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Online medical school-a win for accessibility?
errBMJ-BRITISH MEDICAL JOURNAL
IF42.7
err2022-01-18
err3
errOAAI
errDoherty, Patrick
err分享
err收藏
Genetic Manipulation of sn-1-Diacylglycerol Lipase and CB1 Cannabinoid Receptor Gain-of-Function Uncover Neuronal 2-Linoleoyl Glycerol Signaling in Drosophila melanogastersn-1-Diacylglycerol脂肪酶和CB1大麻素受体功能获得的遗传操作揭示了果蝇中的神经元2-亚油酸甘油信号传导
errCANNABIS AND CANNABINOID RESEARCH
IF2.7
err2021-04-01
err11
errOAAI
errTortoriello, Giuseppe; Beiersdorf, Johannes; Romani, Susana; Williams, Gareth; Cameron, Gary A.; Mackie, Ken; Williams, Michael J.; Di Marzo, Vincenzo; Keimpema, Erik; Doherty, Patrick; Harkany, Tibor
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Alzheimer's Disease Progression in the 5 x FAD Mouse Captured with a Multiplex Gene Expression Array用多重基因表达阵列捕获的5 x FAD小鼠的阿尔茨海默氏病进展
errJOURNAL OF ALZHEIMERS DISEASE
IF3.1
err2019-12-12
err5
PREAI
errGatt, Ariana; Whitfield, David R.; Ballard, Clive; Doherty, Patrick; Williams, Gareth
err分享
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2-Linoleoylglycerol Is a Partial Agonist of the Human Cannabinoid Type 1 Receptor that Can Suppress 2-Arachidonolyglycerol and Anandamide Activity2-亚油酸甘油是1型人类大麻素受体的部分激动剂，可以抑制2-花生四烯酸甘油和Anandamide活性
errCANNABIS AND CANNABINOID RESEARCH
IF2.7
err2019-12-01
err14
errOAAI
errLu, Leanne; Williams, Gareth; Doherty, Patrick
err分享
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Drug repurposing for Alzheimer's disease based on transcriptional profiling of human iPSC-derived cortical neurons基于人iPSC衍生的皮质神经元转录谱的阿尔茨海默病药物再利用
errTRANSLATIONAL PSYCHIATRY
IF6.2
err2019-09-06
err38
errOAAI
errWilliams, Gareth; Gatt, Ariana; Clarke, Earl; Corcoran, Jonathan; Doherty, Patrick; Chambers, David; Ballard, Clive
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No transcriptional evidence for active Nav channels in two classes of cancer cell在两个课程的癌细胞中没有活跃的Nav通道的转录证据
errCHANNELS
IF3.2
err2019-07-22
err1
errOAAI
errHompoonsup, Supanida; Chambers, David; Doherty, Patrick; Williams, Gareth
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Targeted repositioning identifies drugs that increase fibroblast growth factor 20 production and protect against 6-hydroxydopamine-induced nigral cell loss in rats靶向重新定位可确定增加成纤维细胞生长因子20产生并防止6-羟基多巴胺诱导的大鼠黑质细胞丢失的药物
errSCIENTIFIC REPORTS
IF3.9
err2019-06-06
err21
errOAAI
errFletcher, Edward J. R.; Jamieson, Aran D.; Williams, Gareth; Doherty, Patrick; Duty, Susan
err分享
err收藏
Nanoscale Structural Plasticity of the Active Zone Matrix Modulates Presynaptic Function活性区基质的纳米级结构可塑性调节突触前功能
errCELL REPORTS
IF6.9
err2017-03-01
err60
errOAAI
errGlebov, Oleg O.; Jackson, Rachel E.; Winterflood, Christian M.; Owen, Dylan M.; Barker, Ellen A.; Doherty, Patrick; Ewers, Helge; Burrone, Juan
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A novel live cell assay to measure diacylglycerol lipase α activity一种用于测量二酰基甘油脂肪酶 α 活性的新型活细胞测定法
errBIOSCIENCE REPORTS
IF4.7
err2016-05-06
err3
errOAAI
errSingh, Praveen K.; Markwick, Rachel; Howell, Fiona V.; Williams, Gareth; Doherty, Patrick
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Programming of neural cells by (endo) cannabinoids: from physiological rules to emerging therapies(endo) 大麻素对神经细胞的编程: 从生理规则到新兴疗法
errNATURE REVIEWS NEUROSCIENCE
IF26.7
err2014-11-20
err224
errOAAI
errMaccarrone, Mauro; Guzman, Manuel; Mackie, Ken; Doherty, Patrick; Harkany, Tibor
err分享
err收藏
Diacylglycerol lipase α manipulation reveals developmental roles for intercellular endocannabinoid signaling
errSCIENTIFIC REPORTS
IF3.9
err2013-06-28
err28
errOAAI
errKeimpema, Erik; Alpar, Alan; Howell, Fiona; Malenczyk, Katarzyna; Hobbs, Carl; Hurd, Yasmin L.; Watanabe, Masahiko; Sakimura, Kenji; Kano, Masanobu; Doherty, Patrick; Harkany, Tibor
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Nerve growth factor scales endocannabinoid signaling by regulating monoacylglycerol lipase turnover in developing cholinergic neurons神经生长因子通过调节发育中的胆碱能神经元中的单酰基甘油脂肪酶周转来调节内源性大麻素信号传导
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2013-01-14
err39
errOAAI
errKeimpema, Erik; Tortoriello, Giuseppe; Alpar, Alan; Capsoni, Simona; Arisi, Ivan; Calvigioni, Daniela; Hu, Sherry Shu-Jung; Cattaneo, Antonino; Doherty, Patrick; Mackie, Kenneth; Harkany, Tibor
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RalA promotes a direct exocyst-Par6 interaction to regulate polarity in neuronal developmentRalA促进直接exocyst-Par6相互作用以调节神经元发育中的极性
errJOURNAL OF CELL SCIENCE
IF3.6
err2013-01-01
err46
errOAAI
errDas, Amlan; Gajendra, Sangeetha; Falenta, Katarzyna; Oudin, Madeleine J.; Peschard, Pascal; Feng, Shanshan; Wu, Bin; Marshall, Christopher J.; Doherty, Patrick; Guo, Wei; Lalli, Giovanna
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The diacylglycerol lipases: structure, regulation and roles in and beyond endocannabinoid signalling二酰基甘油脂肪酶: 内源性大麻素信号传导中的结构，调控和作用
errPHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
IF4.7
err2012-12-05
err127
errOAAI
errReisenberg, Melina; Singh, Praveen K.; Williams, Gareth; Doherty, Patrick
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Amyloid precursor protein (APP) contributes to pathology in the SOD1G93A mouse model of amyotrophic lateral sclerosis淀粉样蛋白前体蛋白 (APP) 有助于肌萎缩性侧索硬化症SOD1G93A小鼠模型的病理
errHUMAN MOLECULAR GENETICS
IF3.2
err2012-06-07
err53
errOAAI
errBryson, J. Barney; Hobbs, Carl; Parsons, Michael J.; Bosch, Karen D.; Pandraud, Amelie; Walsh, Frank S.; Doherty, Patrick; Greensmith, Linda
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The COX-2 inhibitors, meloxicam and nimesulide, suppress neurogenesis in the adult mouse brainCOX-2抑制剂美洛昔康和尼美舒利抑制成年小鼠大脑中的神经发生
errBRITISH JOURNAL OF PHARMACOLOGY
IF7.7
err2010-03-10
err61
errOAAI
errGoncalves, Maria Beatriz; Williams, Emma-Jane; Yip, Ping; Yanez-Munoz, Rafael J.; Williams, Gareth; Doherty, Patrick
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Overcoming Amino-Nogo-induced Inhibition of Cell Spreading and Neurite Outgrowth by 12-O-Tetradecanoylphorbol-13-acetate-type Tumor Promoters通过12 O-Tetradecanoylphorbol-13-acetate-type肿瘤启动子克服氨基Nogo诱导的细胞扩散和神经突生长抑制
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2010-02-01
err18
errOAAI
errDeng, Kangwen; Gao, Ying; Cao, Zixuan; Graziani, Edmund I.; Wood, Andrew; Doherty, Patrick; Walsh, Frank S.
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A retinoic acid receptor β agonist (CD2019) overcomes inhibition of axonal outgrowth via phosphoinositide 3-kinase signalling in the injured adult spinal cord视黄酸受体 β 激动剂 (CD2019) 通过受伤的成人脊髓中的磷酸肌醇3-激酶信号传导克服了轴突生长的抑制
errNEUROBIOLOGY OF DISEASE
IF5.6
err2010-01-01
err53
errOAAI
errAgudo, Marta; Yip, Ping; Davies, Meirion; Bradbury, Elizabeth; Doherty, Patrick; McMahon, Stephen; Maden, Malcolm; Corcoran, Jonathan P. T.
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Ganglioside inhibition of neurite outgrowth requires Nogo receptor function - Identification of interaction sites and development of novel antagonists神经节苷脂抑制神经突生长需要Nogo受体功能-相互作用位点的鉴定和新型拮抗剂的开发
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2008-06-01
err53
errOAAI
errWilliams, Gareth; Wood, Andrew; Williams, Emma-Jane; Gao, Ying; Mercado, Mary L.; Katz, Alan; Joseph-McCarthy, Diane; Bates, Brian; Ling, Huai-Ping; Aulabaugh, Ann; Zaccardi, Joe; Xie, Yuhong; Pangalos, Menelas N.; Walsh, Frank S.; Doherty, Patrick
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研究方向

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